Scottish Medical Journal最新文献_第2页

Optimising the use of colonoscopy to improve risk stratification for colorectal cancer in symptomatic patients: A decision-curve analysis. 优化结肠镜检查的使用，改善无症状患者的结直肠癌风险分层：决策曲线分析。

IF 1.4 4区医学

Scottish Medical Journal Pub Date : 2024-08-01 Epub Date: 2024-07-23 DOI: 10.1177/00369330241266080

James Lucocq, Emma Barron, Heather Holmes, Peter D Donnelly, Neil Cruickshank

{"title":"Optimising the use of colonoscopy to improve risk stratification for colorectal cancer in symptomatic patients: A decision-curve analysis.","authors":"James Lucocq, Emma Barron, Heather Holmes, Peter D Donnelly, Neil Cruickshank","doi":"10.1177/00369330241266080","DOIUrl":"10.1177/00369330241266080","url":null,"abstract":"Objectives: Pressured healthcare resources make risk stratification and patient prioritisation fundamental issues for the investigation of colorectal cancer (CRC) in symptomatic patients. The present study uses machine learning algorithms and decision strategies to improve the appropriate use of colonoscopy.Design: All symptomatic patients in a single health board (2018-2021) proceeding to colonoscopy to investigate for CRC were included. Machine learning algorithms (NeuralNetwork, randomForest, Logistic regression, Naïve-Bayes and Adaboost) were used to risk-stratify patients for CRC using demographics, symptoms, quantitative faecal immunochemical test (qFIT) and haematological tests. Decision curve analyses were performed to determine the optimal decision strategies.Results: 3776 patients were included (median age, 65; M:F,0.9:1.0) and CRC was identified in 217 patients (5.7%). qFIT > 400 μg Hb/g was the most important variable (%IncMSE = 78.5). RandomForrest had the highest area under curve (0.91) and accuracy (0.80) for CRC. When utilising decision curve analysis (DCA), 30%, 46% and 54% of colonoscopies were saved at accepted CRC probabilities of 1%, 2% and 3%, respectively. RandomForrest modelling had superior net clinical benefit compared to default colonoscopy strategies.Conclusions: MLA-derived decision strategies that account for patient and referrer risk preference reduce colonoscopy demand and carry net clinical benefit compared to default colonoscopy strategies.","PeriodicalId":21683,"journal":{"name":"Scottish Medical Journal","volume":" ","pages":"61-71"},"PeriodicalIF":1.4,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141752632","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ribosome-binding protein-1 (RRBP1) expression in prostate carcinomas and its relationship with clinicopathological prognostic factors. 前列腺癌中核糖体结合蛋白-1（RRBP1）的表达及其与临床病理预后因素的关系。

IF 1.4 4区医学

Scottish Medical Journal Pub Date : 2024-08-01 Epub Date: 2024-05-06 DOI: 10.1177/00369330241245730

Didar Gursoy Kuzuluk, Ilke Evrim Secinti, Tugce Erturk, Sibel Hakverdi, Sadik Gorur, Dilan Ozatlan

{"title":"Ribosome-binding protein-1 (RRBP1) expression in prostate carcinomas and its relationship with clinicopathological prognostic factors.","authors":"Didar Gursoy Kuzuluk, Ilke Evrim Secinti, Tugce Erturk, Sibel Hakverdi, Sadik Gorur, Dilan Ozatlan","doi":"10.1177/00369330241245730","DOIUrl":"10.1177/00369330241245730","url":null,"abstract":"Introduction: Studies in recent years have shown that ribosome-binding protein-1 (RRBP1) is expressed at high rates in many cancers and that it may be a potential prognostic biomarker. The objective of the present study is to determine the RRBP1 expression level in prostatic carcinoma and neighboring non-neoplastic prostate tissue, the relationship between its expression level with prognostic factors, and the role of RRBP1 in the development of prostate cancer.Materials and methods: The study included 45 patients who were diagnosed with prostatic carcinoma and underwent radical prostatectomy in our center between the years 2010 and 2021. Pathology reports were reviewed. Mann-Whitney U test was used for the comparison of RRBP1 and GADPH values of the cases (control and tumoral tissue) between the primary tumor stage (pT) and Gleason score (GS) groups. Hierarchical regression analysis was used to explain the effective variables in explaining the RRBP1 value of the research cases.Results: According to the Mann-Whitney U test, mean and median RRBP1-T values of the cases with GS ≥ 8 were detected to be statistically significantly higher than the mean and median RRBP1-T values of the cases with GS < 8.Conclusion: We found out that RRBP1 was expressed at higher rates in patients with high GS and advanced-stage patients. This result indicated that RRBP1 expression may be important in predicting the prognosis of prostate carcinoma.","PeriodicalId":21683,"journal":{"name":"Scottish Medical Journal","volume":" ","pages":"83-87"},"PeriodicalIF":1.4,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140865195","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Is it time to phase out digital rectal examination (DRE) in prostate cancer screening and diagnosis? 在前列腺癌筛查和诊断中逐步淘汰数字直肠检查 (DRE) 的时机是否成熟？

IF 1.4 4区医学

Scottish Medical Journal Pub Date : 2024-08-01 DOI: 10.1177/00369330241279889

Danny Darlington Carbin, Sidharth Misra, Krishnaji Patil, Venkata Ramana Murthy Kusuma

引用次数: 0

Impact of sarcopenia on outcomes of bladder cancer undergoing radical cystectomy: A systematic review and meta-analysis. 肌肉疏松症对接受根治性膀胱切除术的膀胱癌患者预后的影响：系统回顾与荟萃分析。

IF 2.7 4区医学

Scottish Medical Journal Pub Date : 2024-05-01 Epub Date: 2024-02-29 DOI: 10.1177/00369330241234690

Fanyi Qin, Jiacheng Wu

{"title":"Impact of sarcopenia on outcomes of bladder cancer undergoing radical cystectomy: A systematic review and meta-analysis.","authors":"Fanyi Qin, Jiacheng Wu","doi":"10.1177/00369330241234690","DOIUrl":"10.1177/00369330241234690","url":null,"abstract":"Objective: To provide synthesized evidence on the association between sarcopenia and risk of mortality, recurrence and postoperative complications in patients with bladder cancer and undergoing radical cystectomy (RC).Methods: Only studies with observational design that investigated the association between sarcopenia and outcomes of interest among patients with bladder cancer undergoing RC were included. The outcomes of interest were mortality, recurrence, and postoperative complications. The systematic search was conducted using three large databases, that is, PubMed, EMBASE, and Scopus. A random effects model was used for the analysis and pooled effect sizes were reported as odds ratio (OR) or hazards ratio (HR) along with 95% confidence intervals (CIs).Results: A total of 21 studies with 4997 patients were included. Compared to non-sarcopenic subjects, those with sarcopenia had increased risk of all-cause mortality (HR 1.45, 95% CI: 1.32, 1.61), cancer-specific mortality (HR 1.74, 95% CI: 1.49, 2.03) and a lower recurrence free survival (HR 1.84, 95% CI: 1.30, 2.62). Patients with sarcopenia also had higher risk of developing complications within 90 days postoperatively (OR 1.77, 95% CI: 1.23, 2.55).Conclusion: Sarcopenia among patients with bladder cancer and managed using RC is associated with adverse survival outcomes and an increased risk of postoperative complications.","PeriodicalId":21683,"journal":{"name":"Scottish Medical Journal","volume":" ","pages":"26-36"},"PeriodicalIF":2.7,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139997389","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Challenges and expectations of international medical graduates moving to the UK: An online survey. 移居英国的国际医学毕业生面临的挑战和期望：在线调查。

IF 2.7 4区医学

Scottish Medical Journal Pub Date : 2024-05-01 Epub Date: 2024-02-19 DOI: 10.1177/00369330241229922

Jenni Lane, Nitin Shrotri, Bhaskar K Somani

{"title":"Challenges and expectations of international medical graduates moving to the UK: An online survey.","authors":"Jenni Lane, Nitin Shrotri, Bhaskar K Somani","doi":"10.1177/00369330241229922","DOIUrl":"10.1177/00369330241229922","url":null,"abstract":"Introduction: International medical graduates (IMGs) account for 41% of the UK doctor's workforce but often work in isolated roles, receive minimal constructive feedback regarding their work and offered limited opportunities for career progression. We conducted a survey researching the views of IMGs or doctors from ethnic minority backgrounds on the support given to them.Methods: A survey was carried out on physician demographics, grade and date of first NHS appointment, familiarity and support offered in NHS, induction and study leave, Professional and Linguistic Assessments Board exams and General Medical Council (GMC) referrals. It was drafted via surveymonkey.co.uk platform and circulated via relevant closed medical groups.Results: A total of 173 IMGs and 16 British trained doctors (controls) took the survey. In the IMGs first job, there was no dedicated supervisor, mentor, induction, shadowing period and study leave for 56%, 86%, 52%, 59% and 52%, respectively. Suggestions given for improvements included teaching sessions, mentors, work orientation, supernumerary period and paid induction by 80%, 78%, 76%, 61% and 41% respectively. While 59% of participants knew of another IMG referred to the GMC, the primary reasons given were lack of knowledge of NHS, bias, communication difficulties and cultural differences.Conclusion: This paper reflects the views of doctors regarding the support given to IMGs during their first NHS appointment and subsequent jobs in the NHS. IMGs require a focused and detailed induction, mentorship, educational and clinical supervision throughout their transition to the NHS.","PeriodicalId":21683,"journal":{"name":"Scottish Medical Journal","volume":" ","pages":"53-58"},"PeriodicalIF":2.7,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139906415","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The effect of virtual reality glasses applied during intrauterine device insertion on pain, anxiety and satisfaction: Randomized controlled study. 放置宫内节育器时使用虚拟现实眼镜对疼痛、焦虑和满意度的影响：随机对照研究。

IF 2.7 4区医学

Scottish Medical Journal Pub Date : 2024-05-01 Epub Date: 2024-03-06 DOI: 10.1177/00369330241234688

Tuğba Öz, Nurdan Demirci

{"title":"The effect of virtual reality glasses applied during intrauterine device insertion on pain, anxiety and satisfaction: Randomized controlled study.","authors":"Tuğba Öz, Nurdan Demirci","doi":"10.1177/00369330241234688","DOIUrl":"10.1177/00369330241234688","url":null,"abstract":"Background and aim: This study was carried out to determine the effect of the use of \"virtual reality glasses,\" on anxiety, pain, and satisfaction level in order to reduce anxiety and pain during intrauterine device (IUD) insertion, which is a painful and stressful procedure for women and to divert attention to increase satisfaction.Methods: This randomized controlled study in the gynecology clinic of a state hospital with 80 women who were accepted to participate in the study. Data were collected using structured patient information form, numerical pain rating scale, state-trait anxiety inventory, patient satisfaction evaluation form, and virtual reality glasses.Results: Post-procedural pain scores in the control group after IUD application were higher than post-procedural pain in the virtual reality group. Measurements of post-procedure anxiety in the control group were higher than measurements of post-procedural in the virtual reality group. Satisfaction levels of women with virtual reality glasses during IUD insertion were also found to be high.Conclusions: It was determined that the use of virtual reality glasses, one of the methods of distraction during IUD insertion, was effective in reducing pain and anxiety and increasing patient satisfaction.","PeriodicalId":21683,"journal":{"name":"Scottish Medical Journal","volume":" ","pages":"37-44"},"PeriodicalIF":2.7,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140050356","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Generating evidence, reporting implementation of innovations through use of technology in healthcare: Core purposes of multidisciplinary journal. 通过在医疗保健领域使用技术来生成证据、报告创新的实施情况：多学科期刊的核心宗旨。

IF 2.7 4区医学

Scottish Medical Journal Pub Date : 2024-05-01 DOI: 10.1177/00369330241252024

Ghulam Nabi

引用次数: 0

Scottish Society of Physicians 65th Annual Meeting. 苏格兰医师协会第 65 届年会。

IF 2.7 4区医学

Scottish Medical Journal Pub Date : 2024-05-01 DOI: 10.1177/00369330231225894

引用次数: 0

Patient information videos via QR codes: An innovative and sustainable approach in ophthalmology. 通过 QR 码播放患者信息视频：眼科领域的创新和可持续方法。

IF 1.4 4区医学

Scottish Medical Journal Pub Date : 2024-05-01 Epub Date: 2024-03-01 DOI: 10.1177/00369330241236945

Sirjhun Patel, Wei Han Ong, Caroline Cobb, Stewart Gillan

{"title":"Patient information videos via QR codes: An innovative and sustainable approach in ophthalmology.","authors":"Sirjhun Patel, Wei Han Ong, Caroline Cobb, Stewart Gillan","doi":"10.1177/00369330241236945","DOIUrl":"10.1177/00369330241236945","url":null,"abstract":"Background: We explore an innovative approach by transforming patient information leaflet (PILs) into Quick Response (QR) code linked patient information videos (PIVs) in ophthalmology. Our objectives are to assess the subjective utility of a PIV on glaucoma and analyse the use of QR codes as a delivery method.Methods: A prospective study was conducted in Ninewells Hospital, NHS Tayside. A glaucoma PIV was created and linked to a QR code provided to 130 glaucoma patients. Pre- and post-video questionnaires evaluated the patients' perception of using a QR code and subjective improvement in their understanding of glaucoma.Results: Out of 102 responses collected, 55% of patients had no prior experience with QR codes. However, 81% of patients were able to watch the PIV. The average view duration of the video was 3:26, with 82.5% view retention. Statistically significant improvement in glaucoma knowledge was observed across all six areas questioned (p < 0.001) using a 5-point Likert scale. Overall, 70% of patients preferred PIVs over PILs, and 77% acknowledged that PIVs could be a sustainable alternative.Conclusion: QR codes for delivering PIVs were well-received, with patients finding them easy to use. Our PIV on glaucoma effectively enhanced patients' understanding of the condition.","PeriodicalId":21683,"journal":{"name":"Scottish Medical Journal","volume":" ","pages":"45-52"},"PeriodicalIF":1.4,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139997390","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Retraction notice 撤稿通知

IF 2.7 4区医学

Scottish Medical Journal Pub Date : 2024-04-24 DOI: 10.1177/00369330241240826

引用次数: 0