胰腺胰岛素瘤:我们 15 年的手术经验

IF 1.4 4区 医学 Q2 MEDICINE, GENERAL & INTERNAL
Scottish Medical Journal Pub Date : 2024-11-01 Epub Date: 2024-10-16 DOI:10.1177/00369330241289009
Furkan Karahan, Serkan Karaıslı, Arif Atay, Osman Nuri Dilek, Mehmet Hacıyanlı
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引用次数: 0

摘要

背景:胰岛素瘤是一种罕见的胰腺内分泌肿瘤:胰岛素瘤是一种罕见的胰腺内分泌肿瘤。大多数是良性、散发性和单发的。手术是唯一可治愈的治疗方法。在本研究中,我们介绍了散发性和良性胰岛素瘤围手术期的治疗经验:方法:我们对 2008 年至 2023 年期间在本诊所接受胰岛素瘤手术的患者进行了回顾性研究。对人口统计学数据、首选放射学方法、手术方法以及发病率和死亡率数据进行了评估。研究排除了恶性、侵袭性或家族性多发性内分泌肿瘤突变的患者:19名患者接受了手术,中位年龄为49岁(33-85岁)。最常见的症状是低血糖。74%的病例在术前通过计算机断层扫描确定了肿瘤位置。88%的患者通过触诊和术中超声检查确定了肿瘤位置。最常见的手术方法是切除肿瘤(53%)。三名患者(17%)出现胰瘘。虽然接受去核手术的患者严重发病率较低,但瘘管形成率较高:结论:胰岛素瘤的准确定位对确定适当的手术方法至关重要。去核手术成功率高、发病率低,是适合患者的推荐手术方式。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Pancreatic insulinomas: Our 15-year surgical experience.

Background: Insulinomas are rare endocrine tumors of the pancreas. The majority are benign, sporadic, and solitary. Surgery is the only curative treatment. In this study, we present our experiences with the perioperative management of sporadic and benign pancreatic insulinomas.

Methods: Patients who underwent surgery for pancreatic insulinoma in our clinic between 2008 and 2023 were retrospectively reviewed. Demographic data, preferred radiological methods, surgical procedures, and morbidity and mortality data were evaluated. Patients with malignant, invasive, or familial multiple endocrine neoplasia mutations were excluded from the study.

Results: Nineteen patients underwent surgery, with a median age of 49 years (range: 33-85). Symptoms related to hypoglycemia were the most commonly observed. The tumor location was identified preoperatively in 74% of cases using computed tomography. Palpation and intraoperative ultrasound identified the tumor location in 88% of patients. Enucleation (53%) were the most common surgical procedures. Pancreatic fistula occurred in three patients (17%). While serious morbidity was lower in patients who underwent enucleation, the rate of fistula formation was higher.

Conclusion: The accurate localization of insulinomas plays a crucial role in determining the appropriate surgical procedure. With high success rates and lower morbidity, enucleation is the recommended procedure for suitable patients.

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来源期刊
Scottish Medical Journal
Scottish Medical Journal 医学-医学:内科
CiteScore
4.80
自引率
3.70%
发文量
42
审稿时长
>12 weeks
期刊介绍: A unique international information source for the latest news and issues concerning the Scottish medical community. Contributions are drawn from Scotland and its medical institutions, through an array of international authors. In addition to original papers, Scottish Medical Journal publishes commissioned educational review articles, case reports, historical articles, and sponsoring society abstracts.This journal is a member of the Committee on Publications Ethics (COPE).
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