Scientific Journal for Damietta Faculty of Science最新文献_第7页

Role of Methotrexate and Thyme in Physiological Changes of Male Rat 甲氨蝶呤和百里香在雄性大鼠生理变化中的作用

Scientific Journal for Damietta Faculty of Science Pub Date : 2021-12-01 DOI: 10.21608/sjdfs.2021.240753

eman Khalifaa, N. Omar

引用次数: 0

EFFECTS OF MAGNETIC-ACTIVATED SPERM CELL SORTING TECHNIQUE IN BLASTOCYST FORMATION AFTER INTRACYTOPLASMIC SPERM INJECTION 磁激活精子细胞分选技术对胞浆内精子注射后囊胚形成的影响

Scientific Journal for Damietta Faculty of Science Pub Date : 2021-12-01 DOI: 10.21608/sjdfs.2021.239486

May Elzanatey, Amoura Abou ElNaga, H. El-Gammal, M. El-Zayat

{"title":"EFFECTS OF MAGNETIC-ACTIVATED SPERM CELL SORTING TECHNIQUE IN BLASTOCYST FORMATION AFTER INTRACYTOPLASMIC SPERM INJECTION","authors":"May Elzanatey, Amoura Abou ElNaga, H. El-Gammal, M. El-Zayat","doi":"10.21608/sjdfs.2021.239486","DOIUrl":"https://doi.org/10.21608/sjdfs.2021.239486","url":null,"abstract":"Many sperm preparation procedures are used in intracytoplasmic sperm injection (ICSI), including migration, density gradient centrifugation, and filtering. Magnetic-activated cell sorting (MACS) is a type of magnetic separation that has been used in a variety of biomedical and biological studies. To examine the fertilisation rate, cleavage, and development of Blastocystes in two sperm preparation procedures for ICSI, MACS and density gradient centrifugation (DGC). The research was carried out in the Royal Center in Mansoura, Dakahlia Governorate, Egypt. Fifty patients receiving ICSI had their sperm samples taken. The sperm were separated into two groups using traditional DGC. One group served as DGC, while the other served as MACS. The number of oocytes harvested, the number of metaphase II oocytes injected, fertilisation rates, cleavage rates, and embryo quality were all compared. between MACS and groups. quality, statistically significant difference between the two groups in terms of the of quality and of MII a statistically significant negative connection. in the DGC group, a statistically significant negative connection between sperm DNA fragmentation (SDF) and fertilisation rate. MACS sperm selection of human spermatozoa is a safe, straightforward, and effective procedure for sperm preparation in a clinical environment for ICSI..","PeriodicalId":21655,"journal":{"name":"Scientific Journal for Damietta Faculty of Science","volume":"2014 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86600513","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Impact of Ottelione on Gamma-glutamyl transferase and Hematological markers in mice with Liver Fibrosis Ottelione对肝纤维化小鼠γ -谷氨酰转移酶及血液学指标的影响

Scientific Journal for Damietta Faculty of Science Pub Date : 2021-12-01 DOI: 10.21608/sjdfs.2021.209357

R. Zahran, L. El-Sayed, S. Ayyad

引用次数: 0

Exogenous Application of the Polyamine Spermine Delays Natural Leaf Senescence in Wheat Through Protecting Chlorophyll from Degradation and Preventing Oxidative Stress 外源施用多胺精胺通过保护叶绿素降解和防止氧化胁迫延缓小麦叶片自然衰老

Scientific Journal for Damietta Faculty of Science Pub Date : 2021-09-01 DOI: 10.21608/sjdfs.2021.195589

N. Hassan, H. Ebeed, H. S. Ahmed

引用次数: 0

Comparative Studies on Cladophora Glomerata and Chaetomorpha Vieillardi (Cladophoraceae) at North Delta-Egypt 埃及北三角洲地区Cladophora Glomerata与Chaetomorpha Vieillardi的比较研究

Scientific Journal for Damietta Faculty of Science Pub Date : 2021-09-01 DOI: 10.21608/sjdfs.2021.195582

S. Ahmed, M. Deyab, Radwa S. El-Shanawany, M. El-Adl

{"title":"Comparative Studies on Cladophora Glomerata and Chaetomorpha Vieillardi (Cladophoraceae) at North Delta-Egypt","authors":"S. Ahmed, M. Deyab, Radwa S. El-Shanawany, M. El-Adl","doi":"10.21608/sjdfs.2021.195582","DOIUrl":"https://doi.org/10.21608/sjdfs.2021.195582","url":null,"abstract":"This study aims to compare between the marine alga Chaetomorpha vieillardi and the freshwater alga Cladophora glomerata. Water samples and massive growth of two species were collected from Port Said marine water pond and Ras El-Bar freshwater pond, respectively in 2019. The highly massive growth of Ch. vieillardi and C. glomerata, due to the trophic status and optimal physico-chemical properties of their habitats, causes ecological and economic problems. The very high massive growth of two species leads to relatively complete elimination of dissolved oxygen (DO) at the middle and bottom level of water during the second half of the night. Loss of DO values led to great loss of aquaculture. Although both algal species were belonging to the same family, yet they prefer different habitats where, Ch. vieillardi formed bloom in marine water but C. glomerata in freshwater. The significant variation in the biochemical, phytochemical compositions and heavy metal bioaccumulation capacity of Ch. vieillardi and C. glomerata could be attributed to the variation in biological properties of two species and the physicochemical characteristics of their habitats. Ch. vieillardi has higher carbohydrate and lipid content compared to C. glomerata. Most heavy metals accumulated in C. glomerata was more than that in Ch. vieillardi, but Cu and Fe were highly accumulated in Ch. vieillardi.","PeriodicalId":21655,"journal":{"name":"Scientific Journal for Damietta Faculty of Science","volume":"20 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85601951","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Qualitative and Quantitative Phytochemical Composition of Sargassum Vulgare at Hurghada Red Sea Coast - Egypt 埃及赫尔格达红海沿岸普通马尾藻的定性和定量植物化学成分

Scientific Journal for Damietta Faculty of Science Pub Date : 2021-09-01 DOI: 10.21608/sjdfs.2021.195585

S. Ahmed, M. Deyab, Fatma S. El-Ashry, M. El-Adl

引用次数: 3

Ulva species Blooms and its Biochemical Composition in Relation to Aquatic Environmental Properties at North Damietta- Egypt 埃及北部达米埃塔的藻华及其生化组成与水环境特性的关系

Scientific Journal for Damietta Faculty of Science Pub Date : 2021-09-01 DOI: 10.21608/sjdfs.2021.195590

S. Ahmed, M. Deyab, Amira A.M. Al Afefy, M. El-Adl

引用次数: 0

Phytochemical Components of Two Cyanobacterial Local Strains 两种蓝藻本地菌株的植物化学成分

Scientific Journal for Damietta Faculty of Science Pub Date : 2021-09-01 DOI: 10.21608/sjdfs.2021.195593

M. Deyab, M. El-sheekh, R. Hasan, A. Elsadany, S. Ahmed

引用次数: 4

Association of ITPA Gene Expression and Hematological Abnormalities Induced by Dual therapy in HCV-infected Patients hcv感染患者ITPA基因表达与双重治疗诱导的血液学异常的关系

Scientific Journal for Damietta Faculty of Science Pub Date : 2021-09-01 DOI: 10.21608/sjdfs.2021.195591

N. Elarabany, N. Omar, Mostafa M. Elshaer, A. AbdelKhalek, Maitha Rashed

{"title":"Association of ITPA Gene Expression and Hematological Abnormalities Induced by Dual therapy in HCV-infected Patients","authors":"N. Elarabany, N. Omar, Mostafa M. Elshaer, A. AbdelKhalek, Maitha Rashed","doi":"10.21608/sjdfs.2021.195591","DOIUrl":"https://doi.org/10.21608/sjdfs.2021.195591","url":null,"abstract":"The combination therapy has been the standard treatment for chronic hepatitis C virus (HCV) infection, but many patients have side effects due to this therapy. Recently, new direct-acting antivirals (DAAs) have enhanced the response rate, especially in difficult-to-treat patients infected with HCV genotypes (GT) 1 or 4, and have made adverse effects less common. RBV plays continually an important role in HCV therapy even with the introduction of DAAs. Hemolytic anemia is a common side effect in HCV-infected patients on combination therapy, affecting up to 30 % of patients, which needs to followup hemoglobin and dose modification in up to 15 % of patients. RBV-induced anemia primarily results in the reduction of adenosine triphosphate (ATP) levels in erythrocytes, affecting ATP-dependent oxidative metabolism. Genetic variations in the inosine triphosphatase (ITPA ) gene, which encodes an inosine triphosphate pyrophosphohydrolase (ITPase), protect from hemolytic anemia during dual therapy. These ITPA variants affect ITPase functionality, causing a drop in its activity, resulting in an accumulation of inosine triphosphate (ITP) in erythrocytes and the prevention of oxidative stress. The functional variants in ITPA gene leads to ITPase deficiency and a strong accumulation of ITP in erythrocytes, which is associated with lower RBV-toxicity. These genetic variants have been associated with protection from anemia.","PeriodicalId":21655,"journal":{"name":"Scientific Journal for Damietta Faculty of Science","volume":"29 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90497579","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Possible Therapeutic Role of Bone Marrow-Derived Mesenchymal Stem Cells in a Rat Model of Hepatocellular Carcinoma 骨髓来源间充质干细胞在大鼠肝细胞癌模型中的可能治疗作用

Scientific Journal for Damietta Faculty of Science Pub Date : 2021-09-01 DOI: 10.21608/sjdfs.2021.195596

F. El-Taweel, Sara El-helf, M. Helal, Hatem El-mezayn

{"title":"Possible Therapeutic Role of Bone Marrow-Derived Mesenchymal Stem Cells in a Rat Model of Hepatocellular Carcinoma","authors":"F. El-Taweel, Sara El-helf, M. Helal, Hatem El-mezayn","doi":"10.21608/sjdfs.2021.195596","DOIUrl":"https://doi.org/10.21608/sjdfs.2021.195596","url":null,"abstract":"Hepatocellular carcinoma (HCC) is one of the most common types of cancer and its high mortality and short survival time causes a serious worldwide health burden. Chemotherapy as 5-Flourouracil (5-FU) is used as the first-choice treatment for HCC, however it is associated with resistance, low efficacy and has side effects. Consequently, the administration of mesenchymal stem cells (MSCs) as a novel therapy for HCC holds great promise. MSCs can differentiate into hepatocytes, reduce liver inflammation, promote hepatic regeneration and secrete protective cytokines. This is the first study that sheds new light on the role of MSCs alone or together with 5-FU in HCC. In this study, Bone marrow derived-MSCs were prepared and HCC model was induced via treating rats with N-diethylnitrosamine (DEN). The effect of treatments was evaluated by biochemical, tumor markers, macroscopical, and histopathological analysis. Also, cell cycle, apoptosis assay, KI67 and CD95 were performed by Flowcytometry. The administration of MSCs together with 5-FU yields a decrease in the liver enzymes with down-regulation of tumor markers as well as improvement of histopathological picture. In addition, such treatment decreased cell proliferation that associated with the down-regulation of KI67 expression. Furthermore, MSCs did not mediate the apoptosis pathway together with reduction of CD95 expression and cell cycle arrest at G0/G1 phase. In conclusion, MSCs exerted antitumor effects by inhibiting proliferation, modulating the cell cycle in G0/G1 phase and improved the toxic effect of 5FU via improvement of liver enzymes and decreased tumor markers.","PeriodicalId":21655,"journal":{"name":"Scientific Journal for Damietta Faculty of Science","volume":"40 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80105372","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0