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Rinsho Yakuri\/japanese Journal of Clinical Pharmacology and Therapeutics最新文献

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Elimination of Ritodrine in Mothers Pregnant with Twins and Their Neonatal Twins 双胞胎母亲及其新生儿双胞胎停用利托卡因
Rinsho Yakuri\/japanese Journal of Clinical Pharmacology and Therapeutics Pub Date : 2017-05-31 DOI: 10.3999/JSCPT.48.91
Satoko Fujieda, Mitsuaki Keira, M. Soma, Yoichi Sasaki, A. Konda, Yuji Mukai, T. Toda, N. Inotsume, H. Yoshida
{"title":"Elimination of Ritodrine in Mothers Pregnant with Twins and Their Neonatal Twins","authors":"Satoko Fujieda, Mitsuaki Keira, M. Soma, Yoichi Sasaki, A. Konda, Yuji Mukai, T. Toda, N. Inotsume, H. Yoshida","doi":"10.3999/JSCPT.48.91","DOIUrl":"https://doi.org/10.3999/JSCPT.48.91","url":null,"abstract":"- 94 Abstract This study aimed to clarify the individual elimination kinetics of serum ritodrine in women pregnant with twins and their twin neonates. Serum ritodrine concentrations in 10 twin pregnant women and their twin neonates were measured by liquid chro-matography-tandem mass spectrometry ( LC - MS ／ MS ) using 100 m L of serum. The ritodrine elimination half-life in mothers was 5 . 0 ± 2 . 2 ( 3 . 7 - 11 . 1 ) h ［ mean ± SD ( range )] , while the half-lives of ritodrine in the first and second newborns were 9 . 0 ± 8 . 4 ( 4 . 2 - 29 . 6 ) and 7 . 2 ± 4 . 3 ( 4 . 3 - 13 . 2 ) h, respectively. Large individual differences in the half-life of ritodrine were observed in both mothers and their newborns. Since ritodrine remained in newborn serum for 24 - 48 h after birth, newborns need to be carefully monitored for ritodrine-related complications during","PeriodicalId":21491,"journal":{"name":"Rinsho Yakuri\\/japanese Journal of Clinical Pharmacology and Therapeutics","volume":"19 1","pages":"91-94"},"PeriodicalIF":0.0,"publicationDate":"2017-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86654717","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Feasibility of Converting Data of National Center Biobank Network Catalog to Analysis Data Model 国家中心生物库网络目录数据转换为分析数据模型的可行性
Rinsho Yakuri\/japanese Journal of Clinical Pharmacology and Therapeutics Pub Date : 2017-05-31 DOI: 10.3999/JSCPT.48.95
Iori Sakakibara, K. Ide, Y. Kawasaki
{"title":"Feasibility of Converting Data of National Center Biobank Network Catalog to Analysis Data Model","authors":"Iori Sakakibara, K. Ide, Y. Kawasaki","doi":"10.3999/JSCPT.48.95","DOIUrl":"https://doi.org/10.3999/JSCPT.48.95","url":null,"abstract":"In Japan, the National Center Biobank Network (NCBN), comprising six National Centers (NCs), is one of several operating biobank projects that were launched in 2012 as a clinical basic facility project for next-generation medicine. The NCBN is a network-type and federal-type morphological biobank that uses wide-ranging joint research projects to provide bioresources in cooperation with industry, academia, and the government. 5) Information related to biological specimens (blood, deoxyribonucleic acid[DNA], ribonucleic acid[RNA], blood serum, etc.)is collected and stored at each NC, and patient medical data are collected and controlled at a central biobank in a searchable database. 6) However, at present, limited information can be shared among the six NCs, which is mainly due to the lack of standardization of this information in a universal data format. This variation in data formats has caused many problems for collections at the central biobank owing to independent interpretations at each NC and non-compliant entry methods. Consequently, the NCBN catalog data are not currently utilized by outside researchers. The Clinical Data Interchange Standards Consortium (CDISC) standards are a collection of standard specifications regulated by the CDISC, such as definitions of clinical trial content, communications protocols, and standard formats for electronic application data. In 2004, the U.S. Food and Drug 臨床薬理 Jpn J Clin Pharmacol Ther 2017; 48(3): 95-98 95","PeriodicalId":21491,"journal":{"name":"Rinsho Yakuri\\/japanese Journal of Clinical Pharmacology and Therapeutics","volume":"231 1","pages":"95-98"},"PeriodicalIF":0.0,"publicationDate":"2017-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77484634","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
2 .薬疹:実地診療から 2 .药疹:从实地诊疗开始
Rinsho Yakuri\/japanese Journal of Clinical Pharmacology and Therapeutics Pub Date : 2017-03-31 DOI: 10.3999/JSCPT.48.58
川久保洋
{"title":"2 .薬疹:実地診療から","authors":"川久保洋","doi":"10.3999/JSCPT.48.58","DOIUrl":"https://doi.org/10.3999/JSCPT.48.58","url":null,"abstract":"","PeriodicalId":21491,"journal":{"name":"Rinsho Yakuri\\/japanese Journal of Clinical Pharmacology and Therapeutics","volume":"18 1","pages":"58-66"},"PeriodicalIF":0.0,"publicationDate":"2017-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82075970","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
4 ．薬物有害反応と患者・被験者保護 4 ．薬物有害反応と患者・被験者保護
Rinsho Yakuri\/japanese Journal of Clinical Pharmacology and Therapeutics Pub Date : 2017-03-31 DOI: 10.3999/jscpt.48.73
Toshiyuki Sasaguri
{"title":"4 ．薬物有害反応と患者・被験者保護","authors":"Toshiyuki Sasaguri","doi":"10.3999/jscpt.48.73","DOIUrl":"https://doi.org/10.3999/jscpt.48.73","url":null,"abstract":"","PeriodicalId":21491,"journal":{"name":"Rinsho Yakuri\\/japanese Journal of Clinical Pharmacology and Therapeutics","volume":"110 1","pages":"73-78"},"PeriodicalIF":0.0,"publicationDate":"2017-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89830923","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ethnic and Gender Differences in Genetic Polymorphisms of Tumor Necrosis Factor (TNF) -α in a Japanese Population 日本人群中肿瘤坏死因子(TNF) -α遗传多态性的种族和性别差异
Rinsho Yakuri\/japanese Journal of Clinical Pharmacology and Therapeutics Pub Date : 2017-03-31 DOI: 10.3999/JSCPT.48.21
Jun Hakamata, M. Hashiguchi, T. Tsuru, Takanori Tanaka, S. Irie, Mikiko Shimizu, M. Mochizuki
{"title":"Ethnic and Gender Differences in Genetic Polymorphisms of Tumor Necrosis Factor (TNF) -α in a Japanese Population","authors":"Jun Hakamata, M. Hashiguchi, T. Tsuru, Takanori Tanaka, S. Irie, Mikiko Shimizu, M. Mochizuki","doi":"10.3999/JSCPT.48.21","DOIUrl":"https://doi.org/10.3999/JSCPT.48.21","url":null,"abstract":"","PeriodicalId":21491,"journal":{"name":"Rinsho Yakuri\\/japanese Journal of Clinical Pharmacology and Therapeutics","volume":"29 3 1","pages":"21-26"},"PeriodicalIF":0.0,"publicationDate":"2017-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82731849","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
1 ．薬剤性腎障害について―ガイドラインの目指すもの― 1。关于药物性肾损伤——指南的目标——
Rinsho Yakuri\/japanese Journal of Clinical Pharmacology and Therapeutics Pub Date : 2017-03-31 DOI: 10.3999/JSCPT.48.52
秀一 鶴岡
{"title":"1 ．薬剤性腎障害について―ガイドラインの目指すもの―","authors":"秀一 鶴岡","doi":"10.3999/JSCPT.48.52","DOIUrl":"https://doi.org/10.3999/JSCPT.48.52","url":null,"abstract":"","PeriodicalId":21491,"journal":{"name":"Rinsho Yakuri\\/japanese Journal of Clinical Pharmacology and Therapeutics","volume":"30 1","pages":"52-57"},"PeriodicalIF":0.0,"publicationDate":"2017-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77592451","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
ビソプロロール・テープ剤 8 時間貼付時におけるビソプロロールの放出性と体内動態の評価 对贴布8小时时的比索比洛的释放性和体内动态的评价
Rinsho Yakuri\/japanese Journal of Clinical Pharmacology and Therapeutics Pub Date : 2017-03-31 DOI: 10.3999/JSCPT.48.27
小林 真理子, 知 三星, 一彦 長井, 裕貴 片桐, 大輔 本間, 修治 山﨑, 仁志 山田, 喜正 土下, 哲史 堀, 健太 澤井, 量子 神谷, 弘樹 播磨, 梅蕾 張馬, 賢一 渡邊, 一彦 田中, 和行 上野
{"title":"ビソプロロール・テープ剤 8 時間貼付時におけるビソプロロールの放出性と体内動態の評価","authors":"小林 真理子, 知 三星, 一彦 長井, 裕貴 片桐, 大輔 本間, 修治 山﨑, 仁志 山田, 喜正 土下, 哲史 堀, 健太 澤井, 量子 神谷, 弘樹 播磨, 梅蕾 張馬, 賢一 渡邊, 一彦 田中, 和行 上野","doi":"10.3999/JSCPT.48.27","DOIUrl":"https://doi.org/10.3999/JSCPT.48.27","url":null,"abstract":"","PeriodicalId":21491,"journal":{"name":"Rinsho Yakuri\\/japanese Journal of Clinical Pharmacology and Therapeutics","volume":"49 1","pages":"27-30"},"PeriodicalIF":0.0,"publicationDate":"2017-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80548033","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
3 ．心毒性：QT 延長と心抑制 3。心毒性:QT延长和心抑制
Rinsho Yakuri\/japanese Journal of Clinical Pharmacology and Therapeutics Pub Date : 2017-03-31 DOI: 10.3999/JSCPT.48.67
直樹 松本
{"title":"3 ．心毒性：QT 延長と心抑制","authors":"直樹 松本","doi":"10.3999/JSCPT.48.67","DOIUrl":"https://doi.org/10.3999/JSCPT.48.67","url":null,"abstract":"","PeriodicalId":21491,"journal":{"name":"Rinsho Yakuri\\/japanese Journal of Clinical Pharmacology and Therapeutics","volume":"2016 1","pages":"67-72"},"PeriodicalIF":0.0,"publicationDate":"2017-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88919417","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
5 ．肺毒性：呼吸器系の薬物有害反応 5 ．肺毒性：呼吸器系の薬物有害反応
Rinsho Yakuri\/japanese Journal of Clinical Pharmacology and Therapeutics Pub Date : 2017-03-31 DOI: 10.3999/jscpt.48.79
和博 原田
{"title":"5 ．肺毒性：呼吸器系の薬物有害反応","authors":"和博 原田","doi":"10.3999/jscpt.48.79","DOIUrl":"https://doi.org/10.3999/jscpt.48.79","url":null,"abstract":"","PeriodicalId":21491,"journal":{"name":"Rinsho Yakuri\\/japanese Journal of Clinical Pharmacology and Therapeutics","volume":"31 1","pages":"79-83"},"PeriodicalIF":0.0,"publicationDate":"2017-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76441720","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Relationship between Serious Traffic Accidents and Medications in Patients with Parkinson's Disease 帕金森病患者严重交通事故与用药的关系
Rinsho Yakuri\/japanese Journal of Clinical Pharmacology and Therapeutics Pub Date : 2017-01-01 DOI: 10.3999/JSCPT.48.167
R. Ando, Chieko Yamasaki, H. Iwaki, T. Tsujii, H. Yabe, N. Nishikawa, M. Nagai, M. Nomoto
{"title":"Relationship between Serious Traffic Accidents and Medications in Patients with Parkinson's Disease","authors":"R. Ando, Chieko Yamasaki, H. Iwaki, T. Tsujii, H. Yabe, N. Nishikawa, M. Nagai, M. Nomoto","doi":"10.3999/JSCPT.48.167","DOIUrl":"https://doi.org/10.3999/JSCPT.48.167","url":null,"abstract":"","PeriodicalId":21491,"journal":{"name":"Rinsho Yakuri\\/japanese Journal of Clinical Pharmacology and Therapeutics","volume":"2 1","pages":"167-171"},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83667864","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
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