发布求助
文献互助 智能选刊 最新文献

Rinsho Yakuri\/japanese Journal of Clinical Pharmacology and Therapeutics最新文献

筛选
英文 中文
Clinical Pharmacology of Therapeutic Antibodies for Precision Medicine 精准医学治疗性抗体的临床药理学
Rinsho Yakuri\/japanese Journal of Clinical Pharmacology and Therapeutics Pub Date : 2017-01-01 DOI: 10.3999/JSCPT.48.99
A. Yonezawa
{"title":"Clinical Pharmacology of Therapeutic Antibodies for Precision Medicine","authors":"A. Yonezawa","doi":"10.3999/JSCPT.48.99","DOIUrl":"https://doi.org/10.3999/JSCPT.48.99","url":null,"abstract":"","PeriodicalId":21491,"journal":{"name":"Rinsho Yakuri\\/japanese Journal of Clinical Pharmacology and Therapeutics","volume":"4 1","pages":"99-103"},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89235158","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Quantitative Analysis of Perception Changes in Clinical Trial Participants During Clinical Trials 临床试验中受试者知觉变化的定量分析
Rinsho Yakuri\/japanese Journal of Clinical Pharmacology and Therapeutics Pub Date : 2017-01-01 DOI: 10.3999/JSCPT.48.41
Asumi Kojima, S. Yamazaki, T. Yoshio
{"title":"Quantitative Analysis of Perception Changes in Clinical Trial Participants During Clinical Trials","authors":"Asumi Kojima, S. Yamazaki, T. Yoshio","doi":"10.3999/JSCPT.48.41","DOIUrl":"https://doi.org/10.3999/JSCPT.48.41","url":null,"abstract":"","PeriodicalId":21491,"journal":{"name":"Rinsho Yakuri\\/japanese Journal of Clinical Pharmacology and Therapeutics","volume":"38 1","pages":"41-49"},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89706379","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
A Retrospective Clinical Comparison of Subtype Nonselective and Selective α 1 -Adrenoceptor Antagonists for Lower Urinary Tract Symptoms in Male Patients with Hypertension and Benign Prostatic Hyperplasia 非选择性和选择性α 1 -肾上腺素能受体拮抗剂治疗男性高血压合并良性前列腺增生患者下尿路症状的回顾性临床比较
Rinsho Yakuri\/japanese Journal of Clinical Pharmacology and Therapeutics Pub Date : 2017-01-01 DOI: 10.3999/JSCPT.48.1
M. Kimura, M. Yono, Y. Inoue, K. Furukawa, Mai Fujiyama, T. Oyama, M. Hori, S. Tsuji, Takanori Tanaka, S. Irie
{"title":"A Retrospective Clinical Comparison of Subtype Nonselective and Selective α 1 -Adrenoceptor Antagonists for Lower Urinary Tract Symptoms in Male Patients with Hypertension and Benign Prostatic Hyperplasia","authors":"M. Kimura, M. Yono, Y. Inoue, K. Furukawa, Mai Fujiyama, T. Oyama, M. Hori, S. Tsuji, Takanori Tanaka, S. Irie","doi":"10.3999/JSCPT.48.1","DOIUrl":"https://doi.org/10.3999/JSCPT.48.1","url":null,"abstract":"Antagonists for Lower Urinary Tract Symptoms Although doxazosin, a subtype nonselective a 1 -adrenoceptor antagonist, has been shown to improve hypertension and benign prostatic hyperplasia, it is recommended that the two disease entities should be treated independently with the best available drugs. Therefore, we compared the efficacy and safety of three a 1 -adrenoceptor antagonists with different selectivity for the a 1 -adrenoceptor subtypes; doxazosin, silodosin and tamsulosin, for lower urinary tract symptoms in male patients with hypertension and benign prostatic hyperplasia. In a retrospective study, the medical records of 58 hypertensive patients with benign prostatic hyperplasia treated with doxazosin, silodosin plus amlodipine, or tamsulosin plus amlodipine between January 2013 and December 2015 were evaluated. International Prostate Symptom Score ( I-PSS ) , QOL score and maximum urinary flow rate were assessed at baseline and after a 12-week treatment period in all patients. Treatment with doxazosin and amlodipine resulted in a significant reduction in blood pressure from baseline. Doxazosin, silodosin and tamsulosin were similarly effective in improving total I-PSS, QOL score and maximum urinary flow rate. While dizziness was reported in 1 of the 21 patients receiving doxazosin, abnormal ejaculation was reported with subtype selective a 1 -adrenoceptor antagonists but not with doxazosin. Our data demonstrate that all three a 1 -adrenoceptor antagonists have similar clinical efficacy and that there are slight differences in the adverse event profiles of these drugs. These findings suggest that doxazosin is a safe and effective treatment in hypertensive patients with benign prostatic hyperplasia.","PeriodicalId":21491,"journal":{"name":"Rinsho Yakuri\\/japanese Journal of Clinical Pharmacology and Therapeutics","volume":"12 1","pages":"1-7"},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81529028","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Report of the 2nd Annual Meeting of the Kinki Region of the JSCPT 联委会近畿地区第二次年会报告
Rinsho Yakuri\/japanese Journal of Clinical Pharmacology and Therapeutics Pub Date : 2017-01-01 DOI: 10.3999/jscpt.48.181
Yoichi Yamamoto
{"title":"Report of the 2nd Annual Meeting of the Kinki Region of the JSCPT","authors":"Yoichi Yamamoto","doi":"10.3999/jscpt.48.181","DOIUrl":"https://doi.org/10.3999/jscpt.48.181","url":null,"abstract":"","PeriodicalId":21491,"journal":{"name":"Rinsho Yakuri\\/japanese Journal of Clinical Pharmacology and Therapeutics","volume":"31 24","pages":"181-184"},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91404518","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
4. Drug Development for Refractory Pediatric Intrahepatic Cholestasis by Drug-Repositioning 4. 药物重新定位治疗难治性小儿肝内胆汁淤积症的药物开发
Rinsho Yakuri\/japanese Journal of Clinical Pharmacology and Therapeutics Pub Date : 2017-01-01 DOI: 10.3999/JSCPT.48.117
Hisamitsu Hayashi
{"title":"4. Drug Development for Refractory Pediatric Intrahepatic Cholestasis by Drug-Repositioning","authors":"Hisamitsu Hayashi","doi":"10.3999/JSCPT.48.117","DOIUrl":"https://doi.org/10.3999/JSCPT.48.117","url":null,"abstract":"","PeriodicalId":21491,"journal":{"name":"Rinsho Yakuri\\/japanese Journal of Clinical Pharmacology and Therapeutics","volume":"1 1","pages":"117-119"},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86255170","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
6．Adverse Effects on Brain Function of Psychotropic Drugs, Corticosteroids and Interferon 6．精神药物、皮质类固醇及干扰素对脑功能的不良影响
Rinsho Yakuri\/japanese Journal of Clinical Pharmacology and Therapeutics Pub Date : 2017-01-01 DOI: 10.3999/JSCPT.48.84
K. Kaneko
{"title":"6．Adverse Effects on Brain Function of Psychotropic Drugs, Corticosteroids and Interferon","authors":"K. Kaneko","doi":"10.3999/JSCPT.48.84","DOIUrl":"https://doi.org/10.3999/JSCPT.48.84","url":null,"abstract":"","PeriodicalId":21491,"journal":{"name":"Rinsho Yakuri\\/japanese Journal of Clinical Pharmacology and Therapeutics","volume":"51 1","pages":"84-90"},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84579403","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Investigation of the Development History and Status of Risk Identification for Drugs that Received First Global Approved in Japan 在日本首次获得全球批准的药物的发展历史和风险识别现状的调查
Rinsho Yakuri\/japanese Journal of Clinical Pharmacology and Therapeutics Pub Date : 2017-01-01 DOI: 10.3999/JSCPT.48.9
Yuhei Kanda, Akane Takayama, M. Narukawa
{"title":"Investigation of the Development History and Status of Risk Identification for Drugs that Received First Global Approved in Japan","authors":"Yuhei Kanda, Akane Takayama, M. Narukawa","doi":"10.3999/JSCPT.48.9","DOIUrl":"https://doi.org/10.3999/JSCPT.48.9","url":null,"abstract":"","PeriodicalId":21491,"journal":{"name":"Rinsho Yakuri\\/japanese Journal of Clinical Pharmacology and Therapeutics","volume":"41 1","pages":"9-14"},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90900581","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
The Timing of Decision-Making and Informed Consent ： Patients' Perspective and Experiences of Clinical Trials in Japan 决策和知情同意的时机:日本临床试验的患者观点和经验
Rinsho Yakuri\/japanese Journal of Clinical Pharmacology and Therapeutics Pub Date : 2017-01-01 DOI: 10.3999/JSCPT.48.31
H. Nakada, Sachie Yoshida, E. Arita, K. Muto
{"title":"The Timing of Decision-Making and Informed Consent ： Patients' Perspective and Experiences of Clinical Trials in Japan","authors":"H. Nakada, Sachie Yoshida, E. Arita, K. Muto","doi":"10.3999/JSCPT.48.31","DOIUrl":"https://doi.org/10.3999/JSCPT.48.31","url":null,"abstract":"","PeriodicalId":21491,"journal":{"name":"Rinsho Yakuri\\/japanese Journal of Clinical Pharmacology and Therapeutics","volume":"14 1","pages":"31-39"},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78306136","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Patient Registry and Biobank for Reverse Translational Research on Neurodegenerative Diseases 神经退行性疾病逆向转化研究的患者登记和生物库
Rinsho Yakuri\/japanese Journal of Clinical Pharmacology and Therapeutics Pub Date : 2017-01-01 DOI: 10.3999/JSCPT.48.141
M. Katsuno, A. Hashizume, Harumasa Nakamura, K. Ono, K. Yuji, M. Yamada, Takuya Watanabe, K. Ichimaru, Naoto Kato, Takahiro Inoue, M. Kusama, H. Mizushima, Y. Fujimoto, M. Akimoto, Kiyoshi Kobayashi, K. Ohwaki, Koji Uesugi
{"title":"Patient Registry and Biobank for Reverse Translational Research on Neurodegenerative Diseases","authors":"M. Katsuno, A. Hashizume, Harumasa Nakamura, K. Ono, K. Yuji, M. Yamada, Takuya Watanabe, K. Ichimaru, Naoto Kato, Takahiro Inoue, M. Kusama, H. Mizushima, Y. Fujimoto, M. Akimoto, Kiyoshi Kobayashi, K. Ohwaki, Koji Uesugi","doi":"10.3999/JSCPT.48.141","DOIUrl":"https://doi.org/10.3999/JSCPT.48.141","url":null,"abstract":"","PeriodicalId":21491,"journal":{"name":"Rinsho Yakuri\\/japanese Journal of Clinical Pharmacology and Therapeutics","volume":"46 1","pages":"141-147"},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76290183","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
2. Drug Development for Hereditary Protein Misfolding Diseases 2. 遗传性蛋白质错误折叠疾病的药物开发
Rinsho Yakuri\/japanese Journal of Clinical Pharmacology and Therapeutics Pub Date : 2017-01-01 DOI: 10.3999/JSCPT.48.110
H. Kai, M. Suico, T. Shuto
{"title":"2. Drug Development for Hereditary Protein Misfolding Diseases","authors":"H. Kai, M. Suico, T. Shuto","doi":"10.3999/JSCPT.48.110","DOIUrl":"https://doi.org/10.3999/JSCPT.48.110","url":null,"abstract":"","PeriodicalId":21491,"journal":{"name":"Rinsho Yakuri\\/japanese Journal of Clinical Pharmacology and Therapeutics","volume":"23 1","pages":"110-113"},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88851054","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
首页 上一页
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整，为了账户安全，请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们：info@booksci.cn Book学术提供免费学术资源搜索服务，方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号：481959085
Book学术官方微信