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Rinsho byori. The Japanese journal of clinical pathology最新文献

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[Candida]. (念珠菌)。
Rinsho byori. The Japanese journal of clinical pathology Pub Date : 2020-02-08 DOI: 10.32388/j7tz6u
I. Furuta
{"title":"[Candida].","authors":"I. Furuta","doi":"10.32388/j7tz6u","DOIUrl":"https://doi.org/10.32388/j7tz6u","url":null,"abstract":"The incidence of candidiasis has steadily increased with the number of patients with opportunistic infection. Candidiasis is often observed in patients with leukemia, malignant lymphoma and aplastic anemia, all of whom show immunodeficiency. Factors contributing to the increased incidence of candida infections include the overuse of broad-spectrum antimicrobial agents, and the prolonged survival of patients with immunodeficiency. Candida is a major causative organism of nosocomial infection, as are P. aeruginosa and methicillin-resistant Staphylococcus aureus. The number isolated was greater in the order of C. albicans > C. glabrata > C. tropicalis > C. parapsilosis > C. krusei. C. albicans, which was detected most frequency, was isolated from 60-70% of all samples every year. Isolated frequencies of C. albicans were 66-77% from sputum, 43-70% from urine, and 62-72% from vaginal swabs. In regard to annual changes in deep-seated candidiasis among autopsied cases, the incidence reached a peak in the 1985 to 1988 period, and thereafter decreased. The number of cases with infection of the stomach was largest, followed by the esophagus, the lung and kidney. These cases with deep-seated candidiasis showed low values or levels of lymphocyte, neutrophil, hemoglobin, hemoglobin total protein and total cholesterol.","PeriodicalId":21457,"journal":{"name":"Rinsho byori. The Japanese journal of clinical pathology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79515002","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Bleeding time]. (出血时间)。
Rinsho byori. The Japanese journal of clinical pathology Pub Date : 2020-02-07 DOI: 10.32388/pesssh
H. Takami, Y. Tamai, K. Kariya, Y. Sawada
{"title":"[Bleeding time].","authors":"H. Takami, Y. Tamai, K. Kariya, Y. Sawada","doi":"10.32388/pesssh","DOIUrl":"https://doi.org/10.32388/pesssh","url":null,"abstract":"Bleeding time indicates the interaction of the platelets with the damaged vessel wall and the subsequent formation of the primary hemostatic plug. Bleeding time has been widely used in the diagnosis of bleeding disorders, especially thrombocytopenia, abnormalities in platelet function, vascular disorders, and von Willebrand's disease. There are a number of methods to perform the bleeding time test, but there are significant problems concerning sensitivity, specificity, and reproducibility. To study the inhibitory effects of monoclonal antibodies (anti-vWF, anti-GPIb, and anti-GPIIb/IIIa) on primary hemostasis, these antibodies were infused to normal pigs. Anti-vWF and anti-GPIb antibodies markedly prolonged the bleeding time and inhibited hemostatic plug formation. The anti-GPIIb/IIIa antibody completely inhibited ADP-and collagen-induced platelet aggregation, but no or only mild prolongation of bleeding time was observed. The quantitative bleeding time which measures both the time and the amount of blood loss is useful in the diagnosis of hemorrhagic disorders and in judging the efficacy of the treatment. It will provide important information to understand the mechanism of primary hemostasis.","PeriodicalId":21457,"journal":{"name":"Rinsho byori. The Japanese journal of clinical pathology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81472969","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Aldolase].
Rinsho byori. The Japanese journal of clinical pathology Pub Date : 2020-02-02 DOI: 10.32388/b1cp95
E. Satoyoshi, Y. Homma, T. Sugawara
{"title":"[Aldolase].","authors":"E. Satoyoshi, Y. Homma, T. Sugawara","doi":"10.32388/b1cp95","DOIUrl":"https://doi.org/10.32388/b1cp95","url":null,"abstract":"Aldolase (EC 4.1.2.13) plays an important role in glucose metabolism. Aldolase has a molecular weight of 160 kDa and has three isozymes, namely aldolase A, B and C. The enzyme is probably present in all cells; it occurs in particularly large quantities in the muscles, liver and brain. An increase in serum aldolase is found in myotonic muscular disease, such as progressive muscular dystrophy and polymyositis. The enzyme rises in myocardial infarction, reaches a maximum within 24-48 hours and returns to normal in the course of five days. In these muscular diseases, aldolase A isozyme is elevated. Aldolase activity, especially B isozyme, in serum rises to very high levels in acute hepatitis, but is slightly elevated in cirrhosis, chronic hepatitis and obstructive jaundice. Aldolase becomes elevated in serum with malignant tumors, and isozyme A is predominant in serum. Erythrocytes are also rich in aldolase, and the enzyme rises in hemolytic anemia.","PeriodicalId":21457,"journal":{"name":"Rinsho byori. The Japanese journal of clinical pathology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-02-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80151797","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 6
[Microparticle].
Rinsho byori. The Japanese journal of clinical pathology Pub Date : 2020-02-02 DOI: 10.32388/tjzvbe
S. Nomura
{"title":"[Microparticle].","authors":"S. Nomura","doi":"10.32388/tjzvbe","DOIUrl":"https://doi.org/10.32388/tjzvbe","url":null,"abstract":"","PeriodicalId":21457,"journal":{"name":"Rinsho byori. The Japanese journal of clinical pathology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-02-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79590367","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
[Telomerase]. (端粒酶)。
Rinsho byori. The Japanese journal of clinical pathology Pub Date : 2020-02-02 DOI: 10.32388/3a8fv8
N. Tsuji, N. Watanabe
{"title":"[Telomerase].","authors":"N. Tsuji, N. Watanabe","doi":"10.32388/3a8fv8","DOIUrl":"https://doi.org/10.32388/3a8fv8","url":null,"abstract":"Telomerase, an intranuclear enzyme, binds to telomeres at chromosome ends, helps to elongate telomere length and is closely linked to attainment of cellular immortality, a step in carcinogenesis. Since telomerase activity has been detected in several human tumors and hematopoietic malignancies, this enzyme is thought to be a useful marker for cancer diagnosis. Among the components of telomerase, human telomerase catalytic subunit(hTERT) is the most important regulatory factor for telomerase activity. Therefore, quantitation of hTERT mRNA expression may be a new approach to measuring telomerase activity.","PeriodicalId":21457,"journal":{"name":"Rinsho byori. The Japanese journal of clinical pathology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-02-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81837785","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Correlation of the Blood Test Results Obtained Between Assays Using Microliter-Scale Fingertip Blood Samples Collected with a Novel Blood Collection Device and Conventional Venous Blood Assays]. [新型采血装置采集指尖微量血样与传统静脉血检测血液检测结果的相关性]。
Rinsho byori. The Japanese journal of clinical pathology Pub Date : 2017-03-01
Hajime Iwasawa, Tomoaki Nishimura, Shota Nemotc, Naoki Aikawa, Kiyoaki Watanabe
{"title":"[Correlation of the Blood Test Results Obtained Between Assays Using Microliter-Scale Fingertip Blood Samples Collected with a Novel Blood Collection Device and Conventional Venous Blood Assays].","authors":"Hajime Iwasawa,&nbsp;Tomoaki Nishimura,&nbsp;Shota Nemotc,&nbsp;Naoki Aikawa,&nbsp;Kiyoaki Watanabe","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In this study, we investigated the correlations of values of biochemical and hematological tests obtained using microliter-scale fingertip blood samples collected with a newly developed blood collection device with those using conventional venous blood. Eighty volunteer subjects were enrolled in the study. Blood sam- ples were drawn from the fingertip of the ring finger by a single puncture and 60 μL of each sample was promptly and accurately aspirated into a blood collection chip. Then the chip was tightly sealed with chip container and was shaken to mix the contents without dispersing. For biochemical tests except of HbAlc, blood was collected without anticoagulant and centrifuged to obtain 15 μL of serum which was then diluted with 190 pL of physiological saline for the assay. For hematological tests and HbAlc, the sample was as- sayed with blood collected using EDTA-2K. As a result, a good correlation of the test values was obtained between the assay with fingertip blood and that with venous blood. The correlation coefficients were found to be 0.97 in TG, T-CHO, HDL-C, LDL-C, GLU, ALT, γ-GTP, UA, BUN and HbAlc and ≥ 0.95 for WBC, RBC, Hgb, and Hct. These results suggest that our microliter-scale blood testing can be comparable to the assay using venous blood and may be useful as a rapid and simple test for determination of basic clinical tests near the reference intervals. [Original].</p>","PeriodicalId":21457,"journal":{"name":"Rinsho byori. The Japanese journal of clinical pathology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36996871","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[The Resources and Management Necessary for the Activities of a Disaster Medical Assistance Team]. [灾害医疗援助队活动所需的资源和管理]。
Rinsho byori. The Japanese journal of clinical pathology Pub Date : 2017-03-01
Kenichi Kushibiki
{"title":"[The Resources and Management Necessary for the Activities of a Disaster Medical Assistance Team].","authors":"Kenichi Kushibiki","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>It may not be common for laboratory tests to be employed immediately after a disaster in front-line healthcare settings. However, this is not because laboratory tests are not needed in post-disaster healthcare settings, but because the implementation of triage, which prioritizes the saving of lives, is the initial aim of a Disaster Medical Assistance Team (DMAT). Disaster response ability has been reported to be exerted according to the level of experience. After the Great East Japan earthquake, by the cooperation of related societies and organizations, diagnostic reagents and instruments were supplied to 3 core university hospitals in the affected areas, contributing to building a system whereby necessary medical items could be obtained in three affected Prefectures of the Tohoku region. We should always remember that front-line medical care activities in affected areas are possible due to the backup provided by logistic support teams. The more the system for DMAT is improved, the more effective the support system will be after the super-acute phase of a disaster. [Review].</p>","PeriodicalId":21457,"journal":{"name":"Rinsho byori. The Japanese journal of clinical pathology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36996874","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Blood Transfusion Inspection]. [输血检查]。
Rinsho byori. The Japanese journal of clinical pathology Pub Date : 2017-03-01
Daisuke Ide
{"title":"[Blood Transfusion Inspection].","authors":"Daisuke Ide","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Nearly one-half of all hematopoietic progenitor cell transplantation (HCT) procedures involve recipient- donor ABO incompatibility. ABO-incompatible HCT places the recipient at an increased risk of acute and delayed hemolytic reactions, delayed RBC engraftment, and pure red blood cell aplasia. Additionally, clinical and laboratory evaluations for potential non-ABO, minor RBC antigen-antibody discrepancies may be benefi- cial to facilitate safe transfusions before, during, and after transplantation. It is important for medical tech- nologists to play a role in ABO-incompatible HCT as members of the medical team. Medical technologists should obtain accurate laboratory data and analyze the outcomes in patients receiving ABO-incompatible HCT.</p>","PeriodicalId":21457,"journal":{"name":"Rinsho byori. The Japanese journal of clinical pathology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37171538","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[An Overview of JSLM Guidelines 2015 -So Far and Hereafter-]. [2015年JSLM指南概述-至今和以后-]。
Rinsho byori. The Japanese journal of clinical pathology Pub Date : 2017-03-01
Taiyi Furukawa
{"title":"[An Overview of JSLM Guidelines 2015 -So Far and Hereafter-].","authors":"Taiyi Furukawa","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In the Japanese Society of Laboratory Medicine, we publish guidelines as part of the societies activities and conduct revisions every three years. The current version \"guidelines of laboratory medicine JSLM 2015\" was published at the time of an academic meeting in 2015. The overall constitution is Chapter 1: Inspection approach, Chapter 2: Symptoms, and Chapter 3: Diseases, and the first chapter is the most unique part of these guidelines. Although this constitution has changed little since the 2012 version, the contents of each part cover most of the announcements from the different medical societies concerned and are updated. The guidelines were evaluated and criticized by various users from the point of view of how this kind of resource should be. I think that the desirable direction of these guidelines is to effectively identify the part for \"a medical student, medical education\" and the part for \"the reference of medical tests outside one's specialty\", while expanding the part of medical treatment guidelines consistent with EBM. [Review].</p>","PeriodicalId":21457,"journal":{"name":"Rinsho byori. The Japanese journal of clinical pathology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37157445","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Practice of Disaster Medicine and Clinical Laboratory Tests]. 灾害医学实践与临床检验
Rinsho byori. The Japanese journal of clinical pathology Pub Date : 2017-03-01
Kunihiro Mimura, Satoshi Matsumura
{"title":"[Practice of Disaster Medicine and Clinical Laboratory Tests].","authors":"Kunihiro Mimura,&nbsp;Satoshi Matsumura","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In recent years, Japan has been hit by natural disasters such as earthquakes, typhoons, torrential rains, and heavy snow every year without exception. When such disasters occur, human lives are put at risk. These emergency situations are an unrivaled sphere of activity for physicians, nurses, and emergency life-saving technicians, and the need for these workers becomes the focus of society; however, for advanced rescue in the acute phase of disasters and to prevent disease onset in the chronic phase, clinical laboratory tests are expected to play a major role in developing more accurate diagnoses and promoting prompt medical care. In this paper, I examine whether clinical laboratory tests are beneficial for practicing disaster medicine.</p>","PeriodicalId":21457,"journal":{"name":"Rinsho byori. The Japanese journal of clinical pathology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36996873","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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