Sakarya Medical Journal最新文献

{"title":"COMPARISON OF GALACTOGRAPHY, ULTRASONOGRAPHY AND CONTRAST ENHANCED MAGNETIC RESONANCE IMAGING FINDINGS WITH PATHOLOGY RESULTS IN PATIENTS WITH PATHOLOGIC NIPPLE DISCHARGE","authors":"S. Doğan, Emel Durmuş, Figen Öztürk","doi":"10.31832/smj.1430107","DOIUrl":"https://doi.org/10.31832/smj.1430107","url":null,"abstract":"Objective: The purpose of this study was to evaluate the lesion detection rates of imaging methods by comparing galactography, ultrasonography(US) and contrast enhanced-magnetic resonance imaging(CE-MRI) findings with pathology results in patients with pathologic nipple discharge(PND). \u0000Materials and Methods: Fifty-two female patients with PND were included the study. Radiologic imaging and pathology results of patients were evaluated retrospectively. The lesion detection rates of galactography, US and CE-MRI were evaluated. Galactography findings were evaluated according to modified Galactogram Image Classification System(GICS) and compared with the pathology results. \u0000Results: Galactography was applied in 48 patients. While in 45(93.8%) of 48 patients lesion that causes PND was found on galactography. All of the patients had breast US. In 48(92.3%) patients, causing lesion was found on US. CE-MRI was performed in 33 of 52 patients, and lesion was found in 30 patients(90.9%). Lesion detection rates of galactography, US and CE-MRI findings were similar. \u0000Pathology results of 48 patients(92.3%) were benign, and the results of 3 patients(5.8%) were malignant. The result of 1 patient(2%), there was no lesion on pathologic examination. The sensitivity of galactography, US and CE-MRI were 93.6%, 92.2% and 90.6%, respectively. In the double and triple combinations of imaging methods regarding the lesion detection, sensitivity was found as 100%. \u0000There was no significant relationship between modified GICS scores and pathology results. \u0000Conclusion: The lesion detection rates of galactography, US, and CE-MRI were similar. When imaging methods are used in double and triple combinations, lesion detection rates could be increase.","PeriodicalId":21405,"journal":{"name":"Sakarya Medical Journal","volume":"14 9","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141348549","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Insights into Myelin Oligodendrocyte Glycoprotein Associated Disease (MOGAD): Prevalence, Clinical Manifestations, and Treatment Responses in a Four-Year Retrospective Cohort Study","authors":"Abdulkadir Tunç, Alihan Abdullah Akbaş, Ömer Elçi, Beyzanur Bozkurt, Vasfiye Sezer","doi":"10.31832/smj.1438799","DOIUrl":"https://doi.org/10.31832/smj.1438799","url":null,"abstract":"Introduction: This study aims to delineate the prevalence, clinical characteristics, diagnostic findings, and treatment outcomes of Myelin Oligodendrocyte Glycoprotein Associated Disease (MOGAD) in a cohort over four years, providing a basis for improved diagnostic criteria and therapeutic strategies. \u0000Materials and Methods: In a retrospective cohort study at a tertiary care center, we analyzed medical records of 90 patients presenting with CNS demyelinating symptoms, focusing on those diagnosed with MOGAD based on the International MOGAD Panel criteria. Data on clinical presentation, serum Anti-MOG antibody testing, MRI, VEP scans, CSF analysis, and treatment outcomes were evaluated. \u0000Results: Among the cohort of 90 patients, 7 patients were identified with positive Anti-MOG antibodies, indicating a prevalence of 7.8%. Clinical manifestations varied widely, including optic neuritis, myelitis, and cerebral cortical encephalitis. Diagnostic findings highlighted the absence of oligoclonal bands in CSF analysis and diverse MRI lesions. Most patients responded well to immunosuppressive treatments, though relapses occurred in two cases. The study underscores the heterogeneity of MOGAD presentations and the importance of personalized treatment approaches. \u0000Conclusion: Our findings contribute to the growing understanding of MOGAD, emphasizing its distinct clinical and diagnostic features compared to other CNS demyelinating disorders. The study advocates for the integration of MOG antibody testing in clinical practice to enhance diagnostic accuracy and patient outcomes. Future research should aim at longitudinal and multicentric studies to validate our findings and further refine MOGAD management strategies.","PeriodicalId":21405,"journal":{"name":"Sakarya Medical Journal","volume":" 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140998184","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Psikiyatrik Tanı Alan Çocuk ve Ergenlerin Annelerinin Kaygı-Depresyon ve Suçluluk-Utanç Düzeylerinin Çocuğun Tanısı ile İlişkisi","authors":"Esin Cerit, Dılsad Miniksar","doi":"10.31832/smj.1398723","DOIUrl":"https://doi.org/10.31832/smj.1398723","url":null,"abstract":"Amaç: Araştırmada, psikiyatrik tanısı olan çocuk ve ergenlerin annelerinin depresyon, kaygı ve suçluluk -utanç düzeylerinin çocuğun tıbbi tanısı ile ilişkisinin belirlenmesi amaçlanmıştır. \u0000Gereç ve Yöntemler: Araştırma kesitsel desende, ilişki arayıcı bir çalışmadır. 15.10.2021-15.02.2022 tarihleri arasında ***Üniversitesi Sağlık Uygulama ve Araştırma Merkezi, Çocuk ve Ergen Psikiyatrisi Polikliniğine başvuran 92 hastanın annesi üzerinde yapılmıştır. Veriler, Kişisel Bilgi Formu, Beck Depresyon Envanteri, Beck Anksiyete Ölçeği, Suçluluk Utanç Ölçeği ile toplanmıştır. Çalışma verileri değerlendirilirken kategorik değişkenler için frekans dağılımı (sayı, yüzde), sayısal değişkenler için tanımlayıcı istatistikler (ortalama, standart sapma, minimum, maksimum) verilmiştir. Bağımsız Örneklem t Testi, Tek Yönlü Varyans Analizi, Mann Whitney U testi, Pearson Korelasyon Analizi ve basit doğrusal regresyon analizi verilerin analizinde kullanılmıştır. \u0000Bulgular: Annelerin çocuklarının psikiyatrik tanısına göre BDÖ ve BAÖ puan ortalamaları arasında istatistiksel olarak anlamlı farklılık olduğu saptanmıştır (p","PeriodicalId":21405,"journal":{"name":"Sakarya Medical Journal","volume":"9 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140770525","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effectiveness Of Platelet Markers In Estimating The Amount Of Intraoperative Bleeding In Vertebra Surgery","authors":"Seliman Çeti̇nbulut, Onur Palabıyık, H. Kocayiğit, Ayça TAŞ TUNA, Davut Ceylan","doi":"10.31832/smj.1421647","DOIUrl":"https://doi.org/10.31832/smj.1421647","url":null,"abstract":"AIMS: One of the most important steps in perioperative bleeding management is the predetermination of the patient at risk. Even if there is no hemostatic abnormality in vertebral surgery, which is a major surgery, severe bleeding can be encountered and many perioperative blood transfusions might be required. To date, there are no studies in the literature examining platelet markers in terms of predictivity in intraoperative bleeding during vertebral surgeries. In this study; we investigated the effectiveness of preoperative mean platelet volume (MPV), platelet distribution width (PDW), plateletcrit (PCT), mean platelet volume lymphocyte count ratio (MPVLR), and platelet count to lymphocyte count ratio (PLR) values in predicting the amount of intraoperative bleeding in patients who will undergo vertebral surgery. \u0000METHODS: After the approval from the ethics committee, patients who were planned for vertebral surgery by the neurosurgeon were identified. Patient demographic data such as gender, age, ASA score and body mass index (BMI), MPV, PDW, PCT, MPVLR, and PLR values were recorded. Total surgery time, the number of vertebral transpedicular screwing, and laminectomy levels performed as surgical procedures were recorded. The amount of intraoperative bleeding was determined by calculating the amount of blood accumulated in the aspirator and the amount of blood collected by the sponge during surgery. \u0000RESULTS: Of the 63 patients included in the study, 60.3% (n=38) were female and 39.7% (n=25) were male. The mean age of the patients was 54.7 ± 11 years and the mean BMI was 29.6 ± 4.6. No correlation was found between the amount of bleeding and gender, age, MPV, PDW, PCT, MPVLR, or PLR values. A significantly high correlation was found between amount of bleeding and BMI, duration of surgery, and the number of transpedicular screwing segments. \u0000CONCLUSION: Platelet markers do not appear to have an effect on the amount of bleeding. However, as the BMI increases, the duration of surgery prolongs and the number of transpedicular screw segments increases for which the amount of bleeding increases.","PeriodicalId":21405,"journal":{"name":"Sakarya Medical Journal","volume":"28 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140250899","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Percutaneous Endoscopic Gastrostomy Experience: Early and Late Complications","authors":"E. B. Özşenel, Guldan Kahveci, Zuhal Çalişkan, Sema UÇAK BASAT","doi":"10.31832/smj.1388895","DOIUrl":"https://doi.org/10.31832/smj.1388895","url":null,"abstract":"Background \u0000This study retrospectively evaluated the early and late complications of patients who had a percutaneous endoscopic gastrostomy (PEG) tube placed, discussed complication frequency of different diseases and finally pointed on some advices to reduce complications. \u0000 \u0000Methods \u0000The study was conducted with 99 patients who had a PEG tube placed in the endoscopy unit of a training and research hospital. Patients’ age, gender, diagnosis, types of early and late complications, and complication development rates were evaluated. \u0000 \u0000Results \u0000Mean age of the patients was 70.42±16.75(18-94) years and 48.5% were male. Early complications occurred in 11.1%, of which 6.05% were bleeding at the entry site of the PEG tube, and 5.05% were peristomal infection. 39.4% of the patients had late complications, including tube dislodgement in 18%, infection in 8.1%, aspiration pneumonia in 7.1% and other complications in 6%. No complications were observed in 51.5% of the patients, and early or late complications were observed in 48.5% of the patients. 2% of the patients had both early and late complications. The incidence of late complications was significantly higher in patients with Alzheimer’s disease (p=0.027). \u0000 \u0000Conclusion \u0000In the follow-up of patients who had a PEG tube placed in the previous six months, the most common early complication was bleeding in 6.05%, and the most common late complication was tube dislodgement in 18%. Despite its potential complications, the PEG tube is a safe method for long-term enteral feeding. Alzheimer patients are at risk for late complications more than other diseases.","PeriodicalId":21405,"journal":{"name":"Sakarya Medical Journal","volume":"16 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140250459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Effect Of Proximal Femoral Nail End Position In The Femoral Canal On Clinical And Radiological Outcomes Of Intertrochanteric Fractures","authors":"Mehmet Fevzi Çakmak, Levent Horoz","doi":"10.31832/smj.1350817","DOIUrl":"https://doi.org/10.31832/smj.1350817","url":null,"abstract":"Amaç : İntertrokanterik femurkırıklarında intramedüller çivi tedavisi son yıllarda yaygın olarak kullanılmaktadır. İntertrokanterik kırıkların intramedüller tespitinden sonra mekanik komplikasyon oranları %2-13 arasındadır. Proksimal femoral çivi uygulamasının mekanik başarısızlığına ilişkin risk faktörleri arasında lag vidası konumu, uç-apeks mesafesi, redüksiyon kalitesi ve femur boynu/şaft açısı yer alır. Çalışmamız femoral çivi ucunun femoral kanaldaki konumunun mekanik başarısızlık oranlarına ve radyolojik parametrelere etkisini değerlendirmeyi amaçlamaktadır. \u0000Gereç ve Yöntem : Haziran 2019 ile Eylül 2022 tarihleri arasında intertrokanterik kırık nedeniyle proksimal femur çivisi uygulanan 118 hastanın verileri analiz edildi. Hastalar femur kanalındaki proksimal femoral çivi ucunun pozisyonuna göre üç gruba ayrıldı. Ameliyat sonrası ve takip radyografilerinde uç apeks mesafesi, femur boynu/şaft açısı, redüksiyon kalitesi, lag vida konumu, kaynama süresi ve komplikasyonlar değerlendirildi. \u0000Bulgular : Çalışmaya dahil edilen tüm hastalar değerlendirildiğinde 9 hastada femur boynundan sıyrıldığı görüldü. Medial grupta sıyrılma oranları anlamlı olarak daha yüksekti (n=7, p=0,003). FNSA açısından her üç grupta da birbirinden istatistiksel olarak anlamlı farklar mevcuttu (","PeriodicalId":21405,"journal":{"name":"Sakarya Medical Journal","volume":"46 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140259223","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of the Damage Results of Bullet and Pellet Ammunition in Firearm Injuries Causing Bone Fractures in the Extremities","authors":"Ahmet Atilla Abdioğlu, Kemal Paksoy, Oğuzhan Aslan, Sercan Karadeni̇z, İsmail Yükünç, K. Öner","doi":"10.31832/smj.1399230","DOIUrl":"https://doi.org/10.31832/smj.1399230","url":null,"abstract":"Objective \u0000The spectrum of firearm injuries (FI) is broad and challenging for physicians in terms of diagnosis and treatment. The bullets and pellet ammunition used in FI exhibit different ballistic patterns and cause quite different damage to the body. The aim of this study was to compare the outcomes of bullet and pellet injuries causing bone fractures in the extremities. \u0000Methods \u0000The files of patients who were injured in their extremities due to civilian FI between 2016 and 2020 and who were followed up by the orthopedic clinic due to bone fractures were retrospectively analyzed. Age, gender, injured extremity, presence of infection, presence of vascular injury, presence of nerve injury, total number of operations, length of hospital stay and permanent sequelae were evaluated. Cases with missing files were excluded from the study. Evaluation criteria were compared under two main headings for bullet and pellet ammunition types. \u0000Results \u0000There were a total of 40 cases with a mean age of 43.5 years. The mean follow-up period was 41.5(24-61) months. 39 of the cases were male and 1 was female. There were 28 bullet injuries and 12 pellet injuries. Thirty-two of the cases were lower extremity injuries and 8 were upper extremity injuries. There were significant differences between ammunition type and number of operations (p=0.032).The length of hospital stay was significantly higher in the pellet group (p=0.024, p=0.024. Overall, 12.5% infection, 10% vascular damage, 17.5% nerve damage and 30% permanent sequelae occurred as a result of treatments. There were no significant differences between the groups in terms of infection, vascular injury, nerve injury and permanent sequelae. \u0000Conclusion \u0000When comparing the clinical outcomes of bullets and pellet ammunition, there were many differences in the severity of the injury and the treatment process.","PeriodicalId":21405,"journal":{"name":"Sakarya Medical Journal","volume":"14 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140262234","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Türkiye'de Cerrahi Alanına Yönelik Hasta Şikayetleri: Dijital Platformdaki Yorumların Analizi","authors":"Adem Şentürk, Mevlüt Yordanagi̇l","doi":"10.31832/smj.1402643","DOIUrl":"https://doi.org/10.31832/smj.1402643","url":null,"abstract":"Aim: The purpose of the research is to examine patient complaints made on the internet site \"sikayetvar\" regarding the field of surgery in Turkey. The study also aims to identify common themes in patient complaints about the surgery department, better define the patient population making complaints, and systematically examine the reasons for complaints. \u0000Materials and Methods: In the research designed as a retrospective, the complaints made to the complaintvar.com website were examined using the content analysis method, which is one of the qualitative research methods. In the research, 359 posts on the internet about the general surgery department in Turkey, made on the complaintvar.com site, between January 1, 2023 and November 1, 2023, were examined. Complaints made; They are classified according to gender, whether they are public or private hospitals, whether they are inpatients, outpatients or emergency patients, type of surgical procedure, whether only surgical intervention is performed, whether they are related to other departments, the number of views of the complaint and the subject of the complaint. \u0000Results: In the study, 335 (93.3%) of the complaints were related to the procedures performed in general surgery. It was observed that they received a response to 74 (20.6%) of the complaints. It was observed that the complaints from all outpatient clinic patients were significantly higher than the complaints from ward, surgery and endoscopy patients (p","PeriodicalId":21405,"journal":{"name":"Sakarya Medical Journal","volume":"144 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139842914","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Türkiye'de Cerrahi Alanına Yönelik Hasta Şikayetleri: Dijital Platformdaki Yorumların Analizi","authors":"Adem Şentürk, Mevlüt Yordanagi̇l","doi":"10.31832/smj.1402643","DOIUrl":"https://doi.org/10.31832/smj.1402643","url":null,"abstract":"Aim: The purpose of the research is to examine patient complaints made on the internet site \"sikayetvar\" regarding the field of surgery in Turkey. The study also aims to identify common themes in patient complaints about the surgery department, better define the patient population making complaints, and systematically examine the reasons for complaints. \u0000Materials and Methods: In the research designed as a retrospective, the complaints made to the complaintvar.com website were examined using the content analysis method, which is one of the qualitative research methods. In the research, 359 posts on the internet about the general surgery department in Turkey, made on the complaintvar.com site, between January 1, 2023 and November 1, 2023, were examined. Complaints made; They are classified according to gender, whether they are public or private hospitals, whether they are inpatients, outpatients or emergency patients, type of surgical procedure, whether only surgical intervention is performed, whether they are related to other departments, the number of views of the complaint and the subject of the complaint. \u0000Results: In the study, 335 (93.3%) of the complaints were related to the procedures performed in general surgery. It was observed that they received a response to 74 (20.6%) of the complaints. It was observed that the complaints from all outpatient clinic patients were significantly higher than the complaints from ward, surgery and endoscopy patients (p","PeriodicalId":21405,"journal":{"name":"Sakarya Medical Journal","volume":"1 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139783035","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Penı̇sı̇lı̇n ile Oluşturulan Deneysel Epilepsi Modelinde Seftrı̇aksonun Etkı̇sı̇: Elektrofı̇zyolojı̇k Bı̇r Çalışma","authors":"Zeynep KASAP ACUNGİL, Şeyma Özsoy","doi":"10.31832/smj.1369398","DOIUrl":"https://doi.org/10.31832/smj.1369398","url":null,"abstract":"Introduction: Epilepsy is a set of chronic neurological disorders characterized by seizures associated with abnormal and uncontrolled neuronal activity of the brain. Glutamate is the main excitatory neurotransmitter in the central nervous system. Excitatory amino acid transporter-2 (EAAT2), one of the major glutamate transporters, is responsible for total glutamate intake. Ceftriaxone is a β-lactam antibiotic that increases EAAT-2 expression and functional activity. This study aims to investigate the effects of ceftriaxone on penicillin-induced epileptiform activity by using electrocorticography (ECoG) in anesthetized rats. \u0000Materials and Methods: In this study, 35 Wistar male rats were used. The rats were divided into five groups of 7. In group 1, 2.5 μL 500 IU of penicillin intracranially (i.c.) and 1 ml saline solution and intraperitoneally (i.p.) were given, respectively. In group 2, 200 mg/kg, i.p. of ceftriaxone was administered 30 minutes after penicillin. In group 3, 400 mg/kg of ceftriaxone was administered i.p. 30 minutes after penicillin. 500 mg/kg of sodium valproate was administered i.p. following 30 minutes of penicillin in group 4. In group 5, 400 mg/kg, i.p. of ceftriaxone and 500 mg/kg, i.p. of sodium valproate were administered 30 minutes after penicillin. The rats were placed in a stereotaxic device after the procedure, and electrocorticogram recordings were captured for 180 minutes. \u0000Results: The acute treatment of ceftriaxone reduced spike-wave frequency and spike-wave amplitude of penicillin-induced epileptiform activity in the rats. \u0000Conclusion: These findings suggest that acute ceftriaxone had an anticonvulsant effect on penicillin-induced focal onset epileptic activity. Ceftriaxone may has an anti-epileptogenic potential.","PeriodicalId":21405,"journal":{"name":"Sakarya Medical Journal","volume":" 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139792080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}