血小板标记物在估计椎体手术术中出血量中的有效性

Seliman Çeti̇nbulut, Onur Palabıyık, H. Kocayiğit, Ayça TAŞ TUNA, Davut Ceylan
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摘要

目的:围手术期出血处理最重要的步骤之一是预先确定高危患者。椎体手术是一项大手术,即使没有止血异常,也可能出现严重出血,围手术期可能需要多次输血。迄今为止,还没有文献研究血小板标记物对椎体手术术中出血的预测性。在本研究中,我们调查了术前平均血小板体积(MPV)、血小板分布宽度(PDW)、血小板比容(PCT)、平均血小板体积淋巴细胞计数比值(MPVLR)和血小板计数与淋巴细胞计数比值(PLR)在预测椎体手术患者术中出血量方面的有效性。方法:经伦理委员会批准后,确定了计划由神经外科医生进行脊椎手术的患者。记录患者的人口统计学数据,如性别、年龄、ASA 评分和体重指数(BMI)、MPV、PDW、PCT、MPVLR 和 PLR 值。记录手术总时间、椎体经关节螺钉拧入数和椎板切除术层数。术中出血量通过计算吸血器中的积血量和手术中海绵收集的血量来确定。结果:在纳入研究的 63 名患者中,女性占 60.3%(38 人),男性占 39.7%(25 人)。患者的平均年龄为 54.7 ± 11 岁,平均体重指数为 29.6 ± 4.6。出血量与性别、年龄、MPV、PDW、PCT、MPVLR 或 PLR 值之间没有相关性。出血量与体重指数(BMI)、手术时间和经关节螺钉节段数之间存在明显的高度相关性。结论:血小板标记物似乎对出血量没有影响。然而,随着体重指数(BMI)的增加,手术时间延长,经关节螺钉节段数增加,出血量也随之增加。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Effectiveness Of Platelet Markers In Estimating The Amount Of Intraoperative Bleeding In Vertebra Surgery
AIMS: One of the most important steps in perioperative bleeding management is the predetermination of the patient at risk. Even if there is no hemostatic abnormality in vertebral surgery, which is a major surgery, severe bleeding can be encountered and many perioperative blood transfusions might be required. To date, there are no studies in the literature examining platelet markers in terms of predictivity in intraoperative bleeding during vertebral surgeries. In this study; we investigated the effectiveness of preoperative mean platelet volume (MPV), platelet distribution width (PDW), plateletcrit (PCT), mean platelet volume lymphocyte count ratio (MPVLR), and platelet count to lymphocyte count ratio (PLR) values in predicting the amount of intraoperative bleeding in patients who will undergo vertebral surgery. METHODS: After the approval from the ethics committee, patients who were planned for vertebral surgery by the neurosurgeon were identified. Patient demographic data such as gender, age, ASA score and body mass index (BMI), MPV, PDW, PCT, MPVLR, and PLR values were recorded. Total surgery time, the number of vertebral transpedicular screwing, and laminectomy levels performed as surgical procedures were recorded. The amount of intraoperative bleeding was determined by calculating the amount of blood accumulated in the aspirator and the amount of blood collected by the sponge during surgery. RESULTS: Of the 63 patients included in the study, 60.3% (n=38) were female and 39.7% (n=25) were male. The mean age of the patients was 54.7 ± 11 years and the mean BMI was 29.6 ± 4.6. No correlation was found between the amount of bleeding and gender, age, MPV, PDW, PCT, MPVLR, or PLR values. A significantly high correlation was found between amount of bleeding and BMI, duration of surgery, and the number of transpedicular screwing segments. CONCLUSION: Platelet markers do not appear to have an effect on the amount of bleeding. However, as the BMI increases, the duration of surgery prolongs and the number of transpedicular screw segments increases for which the amount of bleeding increases.
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