IF 4.8 2区医学

Rhinology Pub Date : 2025-03-10 DOI: 10.4193/Rhin24.507

Y Hirayama, M S Shahid, H A Finney, J Muzaffar, M S Haque, R Accorona, H Iftikhar

{"title":"Comparison of outcomes for Draf IIB vs Draf III in endoscopic frontal sinus surgery: a comprehensive systematic review and meta-analysis.","authors":"Y Hirayama, M S Shahid, H A Finney, J Muzaffar, M S Haque, R Accorona, H Iftikhar","doi":"10.4193/Rhin24.507","DOIUrl":"https://doi.org/10.4193/Rhin24.507","url":null,"abstract":"Background: Understanding the factors associated with increased rates of restenosis following Draf procedures is crucial for developing targeted strategies to mitigate complications such as mucocele formation, reduce the need for revision surgeries, and improve long-term patient outcomes.Methodology: A systematic search was conducted using Embase, Medline, CINAHL, AMED, PubMed, and the Cochrane Database on January 17th, 2024. Research articles published in English language were included. Abstracts were independently screened by two reviewers, and data were extracted and assessed for quality in adherence to PRISMA guidelines. Meta- and sub-group analyses were conducted using the REML model and random-effects model to address high heterogeneity and I² values.Results: A total of 96 studies met the inclusion criteria. For the Draf IIB subgroup (15 studies, 239 sinuses), the restenosis rate was 7%, compared to 20% in the Draf III subgroup (40 studies, 1,910 sinuses). Revision surgery rates were 5% for Draf IIB versus 12% for Draf III. Adjuvant interventions, such as steroid-impregnated stents, were associated with improved outcomes, showing an ostium patency OR of 2.20.Conclusion: Draf IIB had superior outcomes compared to Draf III with respect to restenosis and revision surgery. The use of steroid-impregnated stents appears effective in reducing restenosis rates.","PeriodicalId":21361,"journal":{"name":"Rhinology","volume":" ","pages":""},"PeriodicalIF":4.8,"publicationDate":"2025-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143586602","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pocket guide: biologics in upper and lower airways in adults. 袖珍指南：成人上下气道生物制剂。

IF 4.8 2区医学

Rhinology Pub Date : 2025-03-05 DOI: 10.4193/Rhin24.510

W J Fokkens, V Backer, V J Lund, P J Barnes, M Bernal-Sprekelsen, L Bjermer, E de Corso, D M Conti, M E Cornet, Z Diamant, R Djukanovic, M Gaga, P Gevaert, J K Han, C Hopkins, G Joos, B N Landis, S Lau, S E Lee, J Mullol, A T Peters, G K Scadding, S Schneider, B Senior, I D Pavord, S Quirce, D Ryan, M E Wechsler, P W Hellings

引用次数: 0

Caudal septoplasty, a literature review. 尾隔成形术，文献综述。

IF 4.8 2区医学

Rhinology Pub Date : 2025-03-05 DOI: 10.4193/Rhin24.415

A Javed, A Alburaiki, A Kamber Zaidi, M U Farooq, J Limbrick, S Anari

{"title":"Caudal septoplasty, a literature review.","authors":"A Javed, A Alburaiki, A Kamber Zaidi, M U Farooq, J Limbrick, S Anari","doi":"10.4193/Rhin24.415","DOIUrl":"https://doi.org/10.4193/Rhin24.415","url":null,"abstract":"Background: Caudal septal deviation accounts for around five percent of patients with septal deviations that require surgery. The caudal septum provides support to the nasal tip and the deviations can narrow the nasal airway and lead to marked asymmetry in nostril shape. Over-resection of this area can compromise the structural support leading to tip collapse or saddle nose deformity. This necessitates alternative techniques to submucosal resection for surgical correction of caudal septal deviations.Methodology: This study provides a review of different surgical techniques, including open and closed septoplasty in the literature to address caudal septal deviation. Each technique is described along with a surgical illustration, its advantages, limitations, and examples of case studies with surgical outcomes.Results: The submucosal resection is a commonly used method but can only be used if the septal deviation is not involving the L-strut. Other methods include scoring, swinging door, doorstop, and suturing techniques either as a stand-alone or used combined with cutting techniques. Batten graft can be used alone or in conjunction with the other methods. Extracorporeal septoplasty is used in cases of severe deformity.Conclusions: There is a variety of methods to address caudal septal deviation. Correcting the caudal septal deviation requires proper pre-operative planning and accurate execution of surgical techniques. More research on surgical outcomes is needed to improve the evidence base.","PeriodicalId":21361,"journal":{"name":"Rhinology","volume":" ","pages":""},"PeriodicalIF":4.8,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143557852","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Safety and feasibility of the endoscopic endonasal approach to anterior skull base tumour resections in young children. 幼儿前颅底肿瘤切除术采用内窥镜鼻内入路的安全性和可行性。

IF 4.8 2区医学

Rhinology Pub Date : 2025-03-05 DOI: 10.4193/Rhin24.494

M Castellanos, D K Lerner, S A Hamimi, A D Workman, J E Douglas, M A Kohanski, P B Storm, J N Palmer, N D Adappa

引用次数: 0

The prevalence of primary chronic rhinosinusitis in young adults from a Swedish birth cohort.

IF 4.8 2区医学

Rhinology Pub Date : 2025-03-05 DOI: 10.4193/Rhin24.048

K Åberg, A Asarnoj, S K Georén, L O Cardell, I Kull, A Bergström, M Holmström, M van Hage, M Westman

{"title":"The prevalence of primary chronic rhinosinusitis in young adults from a Swedish birth cohort.","authors":"K Åberg, A Asarnoj, S K Georén, L O Cardell, I Kull, A Bergström, M Holmström, M van Hage, M Westman","doi":"10.4193/Rhin24.048","DOIUrl":"https://doi.org/10.4193/Rhin24.048","url":null,"abstract":"Background: Chronic rhinosinusitis (CRS) is common worldwide but scarcely studied among young adults. The aim was to investigate prevalence, clinical features, comorbidity, and mucosal inflammatory patterns of CRS among 24-year-olds in a populationbased study.Method: 3037 subjects from the birth cohort BAMSE (Barn/children Allergy Milieu Stockholm Epidemiology) had complete questionnaire answers on CRS at the 24-year-follow-up. Subjects fulfilling the European Position Paper on Rhinosinusitis (EPOS) criteria of CRS at 16 and/or 24 years (n=141), were invited to a clinical examination. We examined 81 subjects. Sixty-eight subjects were included, of whom 40 had CRSsNP, 2 CRSwNP and 26 CRS symptoms only. Twenty-three controls without CRS from BAMSE were included. Nasal endoscopy was performed, IgE against airborne allergens and cytokine gene expression in nasal lavage (NAL) were analyzed.Results: The questionnaire-based CRS prevalence was 4.1%, of which 2.2% was endoscopically verified. Sensitization to airborne allergens was more often seen among CRSsNP and \"CRS symptoms only\", compared to controls. Among CRS subjects overall, the proportion of asthma, AR, atopic eczema, and sensitization to airborne allergens was significantly higher compared to the rest of the cohort. The gene expression of IL-1b and IL-8 in NAL was elevated among CRSsNP and \"CRS symptoms only\" compared to controls, with a trend for TNF-a and MPO.Conclusions: The prevalence of primary CRS was estimated to 2-4%. There was a significant association between CRS and atopic diseases in this age group. The NAL profile showed signs of type-1 inflammation.","PeriodicalId":21361,"journal":{"name":"Rhinology","volume":" ","pages":""},"PeriodicalIF":4.8,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143557879","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The alchemy of precision and innovation: treating chronic airway inflammatory conditions in 2025.

IF 4.8 2区医学

Rhinology Pub Date : 2025-03-05 DOI: 10.4193/Rhin25.902

M B Soyka

引用次数: 0

Remission in chronic rhinosinusitis with nasal polyps (CRSwNP). 伴有鼻息肉的慢性鼻炎（CRSwNP）病情缓解。

IF 4.8 2区医学

Rhinology Pub Date : 2025-02-21 DOI: 10.4193/Rhin24.457

P W Hellings, E De Corso, V Backer, M Bernal-Sprekelsen, Y Chan, D M Conti, M E Cornet, W J Fokkens, P Gevaert, J Han, C Hopkins, B N Landis, S Lau, S Lee, V J Lund, J Mullol, A Peters, S Schneider, B Senior

引用次数: 0

Analysis of clinical characteristics of fungus ball based on the number of involved sinuses.

IF 4.8 2区医学

Rhinology Pub Date : 2025-02-21 DOI: 10.4193/Rhin23.501

T Yang, C Liu, Y Wang, J Zhou, Y Li, H Wei

{"title":"Analysis of clinical characteristics of fungus ball based on the number of involved sinuses.","authors":"T Yang, C Liu, Y Wang, J Zhou, Y Li, H Wei","doi":"10.4193/Rhin23.501","DOIUrl":"https://doi.org/10.4193/Rhin23.501","url":null,"abstract":"Background: Fungus ball (FB) typically presents unilaterally, with the maxillary sinus being the most commonly affected site.Multi-sinus FB cases are seldom discussed.Methodology: A retrospective study involving 1709 FB patients categorized them into single sinus fungus ball (SSFB), double sinus fungus balls (DSFB), and multiple sinus fungus balls (MSFB) groups for clinical analysis.Results: The SSFB group comprised 1596 patients (93.39%), the DSFB group 111 patients (6.50%), and the MSFB group two patients (0.12%). The prevalence of diabetes mellitus in the DSFB group was higher than that in the SSFB group. A female prevalence was noticed and there was no difference in the sex ratio by age group. On computed tomography (CT), maxillary sinus FB group had higher intralesional hyperdensity than sphenoid sinus FB group. Oppositely, sphenoid sinus FB group had higher lateral sinus wall sclerosis than maxillary sinus FB group.Conclusions: DSFB occurs in a minority of cases but needs to be investigated especially in diabetics given the link between diabetes mellitus and increased DSFB risk. A female predominance is seen in both pre- and postmenopausal women. On CT, the presence of intralesional hyperdensity and lateral sinus wall sclerosis correlates with the location of the FB.","PeriodicalId":21361,"journal":{"name":"Rhinology","volume":" ","pages":""},"PeriodicalIF":4.8,"publicationDate":"2025-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143468908","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Radial intralesional linear calcifications and focal hyperostosis: key points for diagnosis, extension and point of origin identification of sinonasal inverted papilloma.

IF 4.8 2区医学

Rhinology Pub Date : 2025-02-19 DOI: 10.4193/Rhin24.379

E Granell, A Cardesin, D Pallarés, R Sánchez, J R Gras

引用次数: 0

Real-world treatment of chronic rhinosinusitis with dupilumab and omalizumab: results from the Korean National Health Insurance Service database.

IF 4.8 2区医学

Rhinology Pub Date : 2025-02-19 DOI: 10.4193/Rhin24.209

S A Han, J Yoon, B H Kim, J H Park, Y-S Lim, Y B Kim, C G Cho, S-W Park, J Y Kim

{"title":"Real-world treatment of chronic rhinosinusitis with dupilumab and omalizumab: results from the Korean National Health Insurance Service database.","authors":"S A Han, J Yoon, B H Kim, J H Park, Y-S Lim, Y B Kim, C G Cho, S-W Park, J Y Kim","doi":"10.4193/Rhin24.209","DOIUrl":"https://doi.org/10.4193/Rhin24.209","url":null,"abstract":"Background: Biological treatment has proven effective for the treatment of chronic rhinosinusitis with nasal polyps (CRSwNP) and is increasingly prescribed. However, in the real-world, strict adherence to the recommended dose may not be feasible and studies on the actual administration patterns of biologics are limited. This study aimed to evaluate the patterns of real-world use of biologics for CRS in Korea, through the National Health Insurance Service (NHIS).Methods: We analysed data from the NHIS database from January 2010 to March 2024. Patients with CRS or nasal polyp defined by the ICD-10 codes, who had undergone computed tomography, and had a history of being prescribed dupilumab or omalizumab were identified. A total of 808 patients were analysed for their administration patterns and systemic corticosteroid use.Results: Twelve weeks after initiation of therapy, 46.2% of patients received dupilumab at 2-weekly intervals and 53.9% of patients on omalizumab patients were receiving treatment at 2- or 4-week intervals. The annual expense of CRS patients treated with biologics was greater than for those receiving other treatments. The average annual usage of systemic steroids was decreased from 33.0 days to 12.7 days after using biologics.Conclusions: The results of this study which analysed real-world data in a large population, suggest a discrepancy between the recommended dose and real-world administration of biologics. Further studies are warranted on feasible administration schedules that reflect various patient factors and healthcare costs.","PeriodicalId":21361,"journal":{"name":"Rhinology","volume":" ","pages":""},"PeriodicalIF":4.8,"publicationDate":"2025-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143450109","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

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