发布求助
文献互助 智能选刊 最新文献

Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova最新文献

筛选
英文 中文
[HR AND DURATION OF ECG ELEMENTS OF AN ADULT DURING PHYSICAL EXERCISES]. [成人在体育锻炼时心电图要素的小时数和持续时间]。
Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova Pub Date : 2017-02-01
L I Irzhak, E A Dudnikova
{"title":"[HR AND DURATION OF ECG ELEMENTS OF AN ADULT DURING PHYSICAL EXERCISES].","authors":"L I Irzhak,&nbsp;E A Dudnikova","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The degree of heart rate (HR) and of duration PP, PT and TP elements electrocardiogram (ECG) before and after physical exercises (PE) depends on their value in the control, in healthy young girls (n = 21), aged 18.1 ± 0.7 years, body weight 56.5 ± 4.0 kg. The 300 cardiocycles by ECG at II standard lead were registered. Рower of PE was 1 W/kg. The growth of the HR after PE at the time of depolarization and repolarization (PT interval) remains practically unchanged, whereas the duration of the isopotential state of the myocardium (segment TP) is revealed. The PP intervals of long duration are shortened by 60%, low duration - by 30 %. The variability of PP interval in control due to the variability of the TP segment, in the experience of the PT interval was found.</p>","PeriodicalId":21358,"journal":{"name":"Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova","volume":"103 2","pages":"209-16"},"PeriodicalIF":0.0,"publicationDate":"2017-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36476865","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[CHRONIC D2-RECEPTOR BLOCKADE AND BEHAVIOR OF LOW DEPRESSIVE RATS]. 慢性d2受体阻断对低抑郁大鼠行为的影响。
Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova Pub Date : 2017-02-01
A V Chajka, D R Khusainov, I V Cheretaev, I I Koreniuk, A D Nozdracev
{"title":"[CHRONIC D2-RECEPTOR BLOCKADE AND BEHAVIOR OF LOW DEPRESSIVE RATS].","authors":"A V Chajka,&nbsp;D R Khusainov,&nbsp;I V Cheretaev,&nbsp;I I Koreniuk,&nbsp;A D Nozdracev","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The article is devoted to investigation of influence of chronic D2-receptor blockade by haloperidol on behavior low depressive rats. It is shown that chronic D2-receptor blockade by haloperidol (2.5 mg/kg) causes pro-depressant effect on behavior of low depressive rats and leads to the formation of the depressed state. In control and experimental groups, identified circaseptan and circasemiseptan rhythms in the dynamics of the index of depression, characterized by a phase shift relative to each other.</p>","PeriodicalId":21358,"journal":{"name":"Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova","volume":"103 2","pages":"172-81"},"PeriodicalIF":0.0,"publicationDate":"2017-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36476867","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[MOLECULAR AND CELLULAR MECHANISMS OF ANGIOGENESIS IN PHYSIOLOGICAL AND PATHOLOGICAL CONDITIONS]. [生理和病理条件下血管生成的分子和细胞机制]。
Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova Pub Date : 2017-02-01
K A Rubina, V A Tkachuk
{"title":"[MOLECULAR AND CELLULAR MECHANISMS OF ANGIOGENESIS IN PHYSIOLOGICAL AND PATHOLOGICAL CONDITIONS].","authors":"K A Rubina,&nbsp;V A Tkachuk","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In normal conditions vascular system is in equilibrium, the processes of angiogenesis and vascular regression are precisely regulated. The mechanisms underlying the cardiovascular and cancer diseases are the insufficient or excessive angiogenesis, correspondingly. Understanding the mechanisms of angiogenesis is necessary for the development of new approaches to cure these diseases. The fundamental knowledge of the vascular growth and maturation mechanisms formed the basis for the strategy of «therapeutic angiogenesis», which is one of the rapidly developing technologies in regenerative medicine in the world. The strategy is based on the stimulation of blood vessel growth and remodeling in ischemic tissues via administration of recombinant angiogenic factors or genetic constructs for their expression. The same knowledge of the mechanisms of angiogenesis is necessary in the development of new drugs aimed at inhibiting the vascular growth in excessive or aberrant angiogenesis, which escapes the physiological control in various diseases. Herein we review the fundamental molecular and cellular mechanisms of regulation of blood vessel initiation, growth, and stabilization in normal and pathological conditions.</p>","PeriodicalId":21358,"journal":{"name":"Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova","volume":"103 2","pages":"121-37"},"PeriodicalIF":0.0,"publicationDate":"2017-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36474960","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[NFLUENCE OF SPONTANEOUS PARTIAL SENSORY DEPRIVATION ON MALE C57BL/6N MICE BEHAVIOR]. 自发性部分感觉剥夺对雄性c57bl / 6n小鼠行为的影响
Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova Pub Date : 2017-02-01
M A Tur, I V Belozertseva
{"title":"[NFLUENCE OF SPONTANEOUS PARTIAL SENSORY DEPRIVATION ON MALE C57BL/6N MICE BEHAVIOR].","authors":"M A Tur,&nbsp;I V Belozertseva","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Vibrissae loss associated with the peculiarities of the intragroup social interaction may be an important factor affecting the animals’ performance in various behavioral tests. To evaluate the influence of spontaneous partial sensory deprivation as a consequence of the barbering activity of a cage mate, the battery of tests was conducted in male C57Bl/6N mice. The results indicate that the behavior of mice without vibrissae significantly differs from control animals in the tube, open field, social interaction and forced swim tests. Thus, the present findings suggest that vibrissae conditions have to be assessed before the inclusion of animals into experimental groups and/or further considered in data analysis.</p>","PeriodicalId":21358,"journal":{"name":"Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova","volume":"103 2","pages":"161-71"},"PeriodicalIF":0.0,"publicationDate":"2017-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36476864","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[ANTIINFLAMMATORY AND REGENERATIVE EFFECT OF PEPTIDE THERAPY IN THE MODEL OF OBSTRUCTIVE LUNG PATHOLOGY]. [多肽治疗在阻塞性肺病理模型中的抗炎和再生作用]。
Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova Pub Date : 2017-02-01
O N Titova, N A Kuzubova, E S Lebedeva, T N Preobrazhenskaya, E A Surkova, I V Dvorakovskaya
{"title":"[ANTIINFLAMMATORY AND REGENERATIVE EFFECT OF PEPTIDE THERAPY IN THE MODEL OF OBSTRUCTIVE LUNG PATHOLOGY].","authors":"O N Titova,&nbsp;N A Kuzubova,&nbsp;E S Lebedeva,&nbsp;T N Preobrazhenskaya,&nbsp;E A Surkova,&nbsp;I V Dvorakovskaya","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The effect of the tetrapeptide bronchogen on the structural and functional state of the bronchial epithelium and inflammatory activity in the lungs was studied in the chronic obstructive pulmonary disease (COPD) model, created in rats by a 60-day intermittent exposure to nitrogen dioxide. The cell composition and cytokine-enzyme profile of bronchoalveolar lavage fluid (BALF), the content of secretory immunoglobulin A and surfactant protein B in BALF were determined. Following the course of peptide treatment the decreased activity of neutrophilic inflammation with the normalization of cellular composition and profile of pro-inflammatory cytokines and enzymes in the bronchoalveolar space was observed. The structure of bronchial epithelium, disturbed during formation of COPD model, was restored and accompanied by restoration of its functional activity as evidenced by an increase of secretory immunoglobulin A (local immunity marker) and surfactant protein B, responsible for reducing the alveolar surface tension.</p>","PeriodicalId":21358,"journal":{"name":"Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova","volume":"103 2","pages":"201-8"},"PeriodicalIF":0.0,"publicationDate":"2017-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36472965","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[BASIC PHYSIOLOGICAL MECHANISMS OF HUMAN ADAPTATION TO COLD]. [人类适应寒冷的基本生理机制]。
Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova Pub Date : 2017-02-01
M M Saltykova
{"title":"[BASIC PHYSIOLOGICAL MECHANISMS OF HUMAN ADAPTATION TO COLD].","authors":"M M Saltykova","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The article provides an overview of the literature that focuses on the main types of human adaptation to cold and mechanisms for increasing heat production. It is shown that the studies in recent years, aimed at studying the molecular mechanisms of adaptation to cold, confirmed the results of previous physiological studies have demonstrated that the major contribution to adaptive thermogenesis during cooling made by oxidative fibers in skeletal muscle (birds, marsupials, large placental and people) and brown adipose tissue (small placenta, especially rodents). The main sources of thermoregulatory heat generation are the contractile activity (thermoregulatory shivering and muscle tone), the uncoupling of oxidative phosphorylation and decrease in thermodynamic efficiency of the ATP-powered pumps (ATPase), which are induced by noradrenaline and thyroid hormones and accompanied by an increase in the consumption of oxygen and energy substrates. During long-term adaptation to cold the number and activity of mitochondria increase to provide enhanced ATP consumption.</p>","PeriodicalId":21358,"journal":{"name":"Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova","volume":"103 2","pages":"138-51"},"PeriodicalIF":0.0,"publicationDate":"2017-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36474965","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[DETECTION OF OPTICAL INTRINSIC SIGNAL IN SOMATOSENSORY CORTEX OF NEONATAL RATS USING PRINCIPAL COMPONENT ANALYSIS]. [用主成分分析法检测新生大鼠体感觉皮层光学固有信号]。
Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova Pub Date : 2017-02-01
M Yu Sintsov, D S Suchkov, M G Minlebaev
{"title":"[DETECTION OF OPTICAL INTRINSIC SIGNAL IN SOMATOSENSORY CORTEX OF NEONATAL RATS USING PRINCIPAL COMPONENT ANALYSIS].","authors":"M Yu Sintsov,&nbsp;D S Suchkov,&nbsp;M G Minlebaev","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Recordings of the intrinsic optical signal (IOS) are widely used in the functional imaging of the central nervous system in vivo. However, the IOS technique has been mainly described in the adult brain and the possibility of using IOS for the robust functional imaging of the immature brain and the optimal parameters for IOS recording and analysis in the analysis in the immature brain tissue remain largely unknown. Here, we show that the use of the near to infrared light and automatic PCA enable efficient detection of IOS in the neonatal rat pups’ whisker-related somato- sensory cortex during the first three weeks after the birth. IOS detection using automatic PCA survived fourfold artificial noise increase in the baseline, indicating on the robustness of this approach. Thus, our findings indicate that IOS imaging using near infrared light and automatic PCA is efficient technique for the functional imaging of somatosensory cortex in the neonatal rats.</p>","PeriodicalId":21358,"journal":{"name":"Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova","volume":"103 2","pages":"152-60"},"PeriodicalIF":0.0,"publicationDate":"2017-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36474966","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[ROLE OF MAST CELLS IN BRONCHIAL CONTRACTION IN NONALLERGIC OBSTRUCTIVE LUNG PATHOLOGY]. 肥大细胞在非过敏性阻塞性肺病理中支气管收缩中的作用。
Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova Pub Date : 2017-02-01
N A Kuzubova, A N Fedin, E S Lebedeva, O N Titova
{"title":"[ROLE OF MAST CELLS IN BRONCHIAL CONTRACTION IN NONALLERGIC OBSTRUCTIVE LUNG PATHOLOGY].","authors":"N A Kuzubova,&nbsp;A N Fedin,&nbsp;E S Lebedeva,&nbsp;O N Titova","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In model of chronic obstructive pulmonary disease induced in rats by 60-day intermittent exposure to nitrogen dioxide mast cells participation in the mechanism of bronchial smooth muscle contractile activity patterns was evaluated. Since the 31st day, one group of rats was inhaled with sodium cromoglycate every day before the nitrogen dioxide exposure to stabilize the mast cell membrane. The other group (control) hasn’t been treated. Isometric contraction of the bronchial isolated preparations in response to nerve or smooth muscle stimulation were determined. Inhibition of mast cell degranulation and the release of endogenous histamine by stabilizing cell membranes prevented the development of bronchial smooth muscle hyperactivity caused by prolonged inhalation of nitrogen dioxide. It is believed that a mechanism to increase the contractile activity of the bronchial wall smooth muscles is mediated by activation of the transmembrane adenosine receptor in resident mast cells, leading to their partial degranulation with release of histamine, acting on the histamine Hl-receptors with the launch of reflex pathways through intramural ganglion neurons.</p>","PeriodicalId":21358,"journal":{"name":"Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova","volume":"103 2","pages":"193-200"},"PeriodicalIF":0.0,"publicationDate":"2017-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36472962","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[TRANSFORMATION OF GASTROPRO- TECTIVE EFFECT OF STRESS IN PROULCEROGENIC CONSEGUENCE: DEVELOPMENT OF EXPERIMENTAL MODELS]. [应激对胃保护作用的转化:实验模型的建立]。
Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova Pub Date : 2017-02-01
O P Komkova, T T Podvigina, L P Filaretova
{"title":"[TRANSFORMATION OF GASTROPRO- TECTIVE EFFECT OF STRESS IN PROULCEROGENIC CONSEGUENCE: DEVELOPMENT OF EXPERIMENTAL MODELS].","authors":"O P Komkova,&nbsp;T T Podvigina,&nbsp;L P Filaretova","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The present work was focused on the development of experimental models, in which we can observe the transformation of gastroprotective effect of stress into the proulcerogenic one. For this aim the effect chronic stress on the formation of indomethacin (35 mg/kg)-induced gastric erosion or cold restrain (10 or 6 °C)-induced gastric erosion was investigated in rats. For chronic stress rats were repeatedly restrained for 14 days daily (1 h or 4 h mild restrain or 1 h intensive restrain) and examined on day 14. Mild restraining didn’t influence on gastric mucosa. In case of intensive restrain, the protective effect of chronic stress on the gastric mucosa was found. In order to avoid the adaptation to the daily stressor of the same modality, we subjected the rats on a daily for 14 days to unpredictable stressors of various modalities. Even in the case of strong unpredictable chronic stress we observed its gastroprotective effect if the indomethacin or cold restrain (10 °C) were used as ulcerogenic factors. The proulcerogenic effect of unpredictable stress was observed only if cold restrain at 6 °C was used as ulcerogenic factor. In conclusion, the findings again support the idea about the gastroprotective effect of stress, even in regards to chronic stress and demonstrate experimental models of transformation gastroprotective effect of stress to ulcerogenic one.</p>","PeriodicalId":21358,"journal":{"name":"Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova","volume":"103 2","pages":"182-92"},"PeriodicalIF":0.0,"publicationDate":"2017-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36476866","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[REACTIVITY AND RESISTANCE OF THE SPINAL STRUCTURES WHEN PERFORMING INSTRUMENTAL CORRECTION OF SPINAL DEFORMITIES]. [脊柱畸形器械矫正时脊柱结构的反应性和阻力]。
Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova Pub Date : 2016-12-01
A P Shein, G A Krivoruchko, S O Ryabykh
{"title":"[REACTIVITY AND RESISTANCE OF THE SPINAL STRUCTURES WHEN PERFORMING INSTRUMENTAL CORRECTION OF SPINAL DEFORMITIES].","authors":"A P Shein,&nbsp;G A Krivoruchko,&nbsp;S O Ryabykh","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The aim of the study was the electroneuromyographic evaluation of the spinal cord pyramidal structures reactivity and resistance in response to the impact of intraoperative factors associated with the application of technologies instrumental correction of spinal deformities of various etiologies and degrees of severity, realized with the help of submersible transpedicular fixation systems. Before treatment and 4-31 (9.6 ± 0.3) days after surgery using methods of global and stimulation (M-responses) electroneuromyography were examined 135 patients 8-50 (16.4 ± 0.6) years (42 male, 93 female) with spinal deformities of various etiologies and severity. The intrao perative maximum angle correction of the spinal column ranged from 3° to 95° (37.2 ± 1.5°). To assess the reactivity of the spinal cord structures located at the top of the primary arc deformation used integral index - the index of sensorimotor deficit (ISD). The lowest values of ISD and most distinct postoperative negative trends of this indicator were observed in persons with spinal deformities of neuromuscular etiology.</p>","PeriodicalId":21358,"journal":{"name":"Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova","volume":"102 12","pages":"1495-1504"},"PeriodicalIF":0.0,"publicationDate":"2016-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36477600","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
首页 上一页 下一页 尾页
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整，为了账户安全，请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们：info@booksci.cn Book学术提供免费学术资源搜索服务，方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号：481959085
Book学术官方微信