Rheumatology Advances in Practice最新文献

Pain management in people with inflammatory arthritis: British Society for Rheumatology guideline scope. 炎症性关节炎患者的疼痛管理：英国风湿病学会指南范围。

IF 2.1

Rheumatology Advances in Practice Pub Date : 2024-11-19 eCollection Date: 2024-01-01 DOI: 10.1093/rap/rkae128

Ian C Scott, Opeyemi Babatunde, Christopher Barker, Rebecca Beesley, Richard Beesley, Hollie Birkinshaw, Mel Brooke, Hema Chaplin, Lara Chapman, Coziana Ciurtin, James Dale, Dervil Dockrell, Emma Dures, Kathyrn Harrison, Meghna Jani, Charlotte Lee, Maura McCarron, Christian D Mallen, Assie O'Connor, Claire Pidgeon, Tamar Pincus, Dee Pratt, Yeliz Prior, Karim Raza, Zoe Rutter-Locher, Seema Sharma, Katie Shaw, Samantha Small, Tilli Smith, Lesley Tiffin, Jordan Tsigarides, Mikalena Xenophontos, Nicholas G Shenker

{"title":"Pain management in people with inflammatory arthritis: British Society for Rheumatology guideline scope.","authors":"Ian C Scott, Opeyemi Babatunde, Christopher Barker, Rebecca Beesley, Richard Beesley, Hollie Birkinshaw, Mel Brooke, Hema Chaplin, Lara Chapman, Coziana Ciurtin, James Dale, Dervil Dockrell, Emma Dures, Kathyrn Harrison, Meghna Jani, Charlotte Lee, Maura McCarron, Christian D Mallen, Assie O'Connor, Claire Pidgeon, Tamar Pincus, Dee Pratt, Yeliz Prior, Karim Raza, Zoe Rutter-Locher, Seema Sharma, Katie Shaw, Samantha Small, Tilli Smith, Lesley Tiffin, Jordan Tsigarides, Mikalena Xenophontos, Nicholas G Shenker","doi":"10.1093/rap/rkae128","DOIUrl":"10.1093/rap/rkae128","url":null,"abstract":"Pain is a common symptom in people with inflammatory arthritis (IA), which has far-reaching impacts on their lives. Recent electronic health record studies demonstrate that UK-based pain care in people with IA commonly involves the prescribing of long-term opioids and gabapentinoids, despite an absence of trial evidence for their efficacy. Patient surveys suggest that non-pharmacological pain management is underused. A UK-specific guideline on pain management for people with IA is required to resolve this. This scoping document outlines the context and prioritized clinical questions for the first British Society for Rheumatology (BSR) guideline on pain management for people with IA. The guideline aims to provide evidence-based recommendations on how pain can be best managed in people with IA (including its assessment, and pharmacological and non-pharmacological treatments), ensuring that people with IA in the UK are offered evidence-based pain management strategies. The guideline is for healthcare professionals involved in the care of people with IA of all ages and genders, people with IA and their families and carers, NHS managers and healthcare commissioners, and other relevant stakeholders such as patient organizations. It will be developed using the methods outlined in the BSR's 'Creating Clinical Guidelines' protocol.","PeriodicalId":21350,"journal":{"name":"Rheumatology Advances in Practice","volume":"8 4","pages":"rkae128"},"PeriodicalIF":2.1,"publicationDate":"2024-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11573413/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142676780","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Scleroderma renal crisis, an increasingly rare but persistently challenging condition: a retrospective cohort study. 硬皮病肾危象：一项回顾性队列研究，一种日益罕见但持续存在的棘手病症。

IF 2.1

Rheumatology Advances in Practice Pub Date : 2024-10-28 eCollection Date: 2024-01-01 DOI: 10.1093/rap/rkae131

Rushab C Shah, Kathleen Morrisroe, Wendy Stevens, Nava Ferdowsi, Susanna Proudman, Mandana Nikpour, Laura J Ross

{"title":"Scleroderma renal crisis, an increasingly rare but persistently challenging condition: a retrospective cohort study.","authors":"Rushab C Shah, Kathleen Morrisroe, Wendy Stevens, Nava Ferdowsi, Susanna Proudman, Mandana Nikpour, Laura J Ross","doi":"10.1093/rap/rkae131","DOIUrl":"10.1093/rap/rkae131","url":null,"abstract":"Objective: Scleroderma renal crisis (SRC) is associated with high morbidity and mortality and there remain unmet needs regarding early identification and treatment. We aimed to assess risk factors for and the outcomes of SRC at a large Australian tertiary hospital.Methods: Seventeen incident SRC cases were diagnosed between 2012 and 2022. Demographic, SSc manifestations and treatment data were extracted. Using data from the Australian Scleroderma Cohort Study (n = 483), logistic regression analysis was performed to identify risk factors for SRC.Results: The prevalence of SRC was 3.52%. The median SSc disease duration at SRC onset was 2 years [interquartile range (IQR) 1-4]. Peak creatinine occurred at a median of 11 days (IQR 5-14) post-SRC diagnosis, with a median peak creatinine of 144 µmol/l (IQR 86-306). Nine (52.94%) SRC patients had evidence of acute neurologic and/or cardiac complications. Acute haemofiltration was required in 3 (17.65%) patients. Over the follow-up period, 7 (41.18%) SRC patients died 2.75 years (IQR 0.74-7.25) after SRC onset. Patients with SRC were more likely to be male [odds ratio (OR) 9.73 (95% CI 3.57, 26.56)], have diffuse disease [OR 23.16 (95% CI 5.22, 102.80)] and have antibodies to Scl70 [OR 3.34 (95% CI 1.24, 9.04)] or RNA polymerase III (RNAPIII) [OR 5.15 (95% CI 1.91, 13.89)].Conclusion: SRC is an uncommon manifestation, but outcomes remain poor. A significant proportion of patients presenting with SRC in Australia are positive for Scl70 or RNAPIII antibody. Despite relatively low peak serum creatinine and rates of renal replacement therapy, SRC was still associated with significant mortality.","PeriodicalId":21350,"journal":{"name":"Rheumatology Advances in Practice","volume":"8 4","pages":"rkae131"},"PeriodicalIF":2.1,"publicationDate":"2024-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11565229/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142648536","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Current and future advances in practice: SAPHO syndrome and chronic non-bacterial osteitis (CNO). 当前和未来的实践进展：SAPHO 综合征和慢性非细菌性骨炎 (CNO)。

IF 2.1

Rheumatology Advances in Practice Pub Date : 2024-10-14 eCollection Date: 2024-01-01 DOI: 10.1093/rap/rkae114

Victoria Furer, Mitsumasa Kishimoto, Tetsuya Tomita, Ori Elkayam, Philip S Helliwell

{"title":"Current and future advances in practice: SAPHO syndrome and chronic non-bacterial osteitis (CNO).","authors":"Victoria Furer, Mitsumasa Kishimoto, Tetsuya Tomita, Ori Elkayam, Philip S Helliwell","doi":"10.1093/rap/rkae114","DOIUrl":"https://doi.org/10.1093/rap/rkae114","url":null,"abstract":"Synovitis, acne, pustulosis, hyperostosis and osteitis (SAPHO) syndrome is a rare, underdiagnosed disease with a wide clinical spectrum. Sterile bone inflammation, predominantly of the anterior chest, and skin manifestations (palmoplantar pustulosis, psoriasis vulgaris and acne) are the key features of SAPHO, which shares certain similarities with SpA. SAPHO is closely related to paediatric chronic non-bacterial osteitis (CNO), a spectrum of autoinflammatory bone diseases. The aetiology of SAPHO is considered multifactorial based on a complex interplay of genetic, immune and infectious factors. Despite the increasing awareness of SAPHO/CNO, diagnostic delay is common, as validated classification and diagnostic criteria are lacking. Treatment of SAPHO represents a challenge and includes anti-inflammatory drugs, antibiotics, bisphosphonates, synthetic conventional DMARDs and off-label use of anti-cytokine biologics and Janus kinase inhibitors. This review summarizes the current diagnostic and practical treatment approach to SAPHO/CNO and highlights the ongoing research endeavours concerning the definition and validation of diagnostic criteria, core domains and treatment.","PeriodicalId":21350,"journal":{"name":"Rheumatology Advances in Practice","volume":"8 4","pages":"rkae114"},"PeriodicalIF":2.1,"publicationDate":"2024-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11474108/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142485874","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Use of over-the-counter supplements, sleep aids and analgesic medicines in rheumatology: results of a cross-sectional survey. 风湿病患者使用非处方补充剂、助眠剂和镇痛药的情况：横断面调查结果。

IF 2.1

Rheumatology Advances in Practice Pub Date : 2024-10-09 eCollection Date: 2024-01-01 DOI: 10.1093/rap/rkae129

Mehreen Soomro, Stephanie Lyons, Ramiro Bravo, John McBeth, Mark Lunt, William G Dixon, Meghna Jani

{"title":"Use of over-the-counter supplements, sleep aids and analgesic medicines in rheumatology: results of a cross-sectional survey.","authors":"Mehreen Soomro, Stephanie Lyons, Ramiro Bravo, John McBeth, Mark Lunt, William G Dixon, Meghna Jani","doi":"10.1093/rap/rkae129","DOIUrl":"https://doi.org/10.1093/rap/rkae129","url":null,"abstract":"Objectives: Pain, fatigue and sleep disturbances are common symptoms in patients with rheumatic and musculoskeletal diseases (RMDs) that may prompt the use of over-the-counter (OTC) supplements, sleep aids and analgesics as self-management strategies. This study evaluated the prevalence of OTC supplements, sleep aids and pain relievers and the financial burden associated with their use in rheumatology.Methods: A web-based survey developed with patients was administered in rheumatology clinics in an English hospital. Participants shared demographic information and detailed their use of OTC supplements, sleep aids and pain relief in the past week. The data were analysed using descriptive statistics and logistic regression models to identify influencing factors.Results: A total of 876 people consented to participate in the survey. More than half of patients (54.5%) reported daily supplement intake, typically spending £10/month (interquartile range 5-20), ranging up to £200/month. The most commonly administered supplements were vitamin D, multivitamins, vitamin C, vitamin B/B complex and omega-3/-6 supplements, with multiple overlaps. Prescription, OTC or non-prescription pain relief use was reported by 82% of respondents, with sleep aids being used by 13%. Of the 327 patients who took NSAIDs, 165 (50.4%) also reported taking OTC supplements, while among the 131 patients using opioids (20.5%), 66 (50.3%) reported supplement use, some of which have documented interactions.Conclusion: The use of OTC supplements, pain relief and sleep aids is common in patients with RMDs. Healthcare professionals should be encouraged to proactively ask about these during consultations, especially from a drug safety perspective, but also to provide timely, reliable advice about such strategies that may be sought by patients.","PeriodicalId":21350,"journal":{"name":"Rheumatology Advances in Practice","volume":"8 4","pages":"rkae129"},"PeriodicalIF":2.1,"publicationDate":"2024-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11543522/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142627133","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

GP consultations and prescribed treatments for Raynaud's: a survey among primary Raynaud's patients in the community. 雷诺氏症的全科医生咨询和处方治疗：一项针对社区雷诺氏症初诊患者的调查。

IF 2.1

Rheumatology Advances in Practice Pub Date : 2024-10-08 eCollection Date: 2024-01-01 DOI: 10.1093/rap/rkae126

Anthony Chen, Stephanie J Lax, Matthew J Grainge, Peter C Lanyon, Fiona A Pearce, Nick Jeffries-Owens, Sue Farrington

引用次数: 0

The relationship between Zoster serology, vaccination uptake and infection rates: a single-centre cross-sectional study. 带状疱疹血清学、疫苗接种率和感染率之间的关系：一项单中心横断面研究。

IF 2.1

Rheumatology Advances in Practice Pub Date : 2024-10-08 eCollection Date: 2024-01-01 DOI: 10.1093/rap/rkae127

Saad Ahmed, Martin Lauran, Adaeze Ugwoke, Tom Walton, Chris Holroyd, James Galloway

{"title":"The relationship between Zoster serology, vaccination uptake and infection rates: a single-centre cross-sectional study.","authors":"Saad Ahmed, Martin Lauran, Adaeze Ugwoke, Tom Walton, Chris Holroyd, James Galloway","doi":"10.1093/rap/rkae127","DOIUrl":"10.1093/rap/rkae127","url":null,"abstract":"Objective: This study aimed to assess the prevalence of Varicella-Zoster Virus (VZV) immunity, vaccination uptake and incidence of VZV-related events in inflammatory arthritis (IA) patients initiating biologic or targeted synthetic disease-modifying antirheumatic drugs.Methods: An observational study was conducted in a single hospital between March 2019 and December 2020. Ninety-three IA patients were included. Data were collected from electronic health records and analysed using the chi-squared test.Results: The majority of patients (91.4%) were seropositive for VZV, reaffirming the necessity for vaccination. In total, 8.6% of the cohort received the Zostavax vaccine, despite a small yet significant number of patients (4.3%) experiencing Herpes Zoster after initiating treatment. Multiple factors contributed to low vaccine uptake, including limited vaccine availability, discrepancies between the British Society for Rheumatology and Joint Committee on Vaccination and Immunisation guidelines, vaccine hesitancy and concerns regarding vaccine efficacy and risks.Discussion: Significant VZV immunity exists among patients prior to targeted therapy commencement. Risk factors for VZV-related events include Janus kinase inhibition, increasing age and long-term steroid use. VZV-related events occurred exclusively in patients with prior viral immunity. Despite most patients having serological evidence of prior VZV exposure, our study exposes critical gaps between current clinical guidelines and practice, particularly in VZV vaccine uptake. Barriers to vaccination include inconsistent guidelines, limited vaccine availability and patient-level hesitancy. This is concerning as our cohort demonstrated small but significant rates of zoster, mostly among patients on long-term steroids.","PeriodicalId":21350,"journal":{"name":"Rheumatology Advances in Practice","volume":"8 4","pages":"rkae127"},"PeriodicalIF":2.1,"publicationDate":"2024-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11513334/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142522878","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Support needs of gout patients and suitability of eHealth to address these needs. 痛风患者的支持需求以及电子医疗满足这些需求的适宜性。

IF 2.1

Rheumatology Advances in Practice Pub Date : 2024-10-04 eCollection Date: 2024-01-01 DOI: 10.1093/rap/rkae125

Jeffrey van der Ven, Bart J F van den Bemt, Floor Ariaans, Johanna E Vriezekolk, Marcel Flendrie, Lise M Verhoef

{"title":"Support needs of gout patients and suitability of eHealth to address these needs.","authors":"Jeffrey van der Ven, Bart J F van den Bemt, Floor Ariaans, Johanna E Vriezekolk, Marcel Flendrie, Lise M Verhoef","doi":"10.1093/rap/rkae125","DOIUrl":"https://doi.org/10.1093/rap/rkae125","url":null,"abstract":"Objectives: To investigate the support needs of patients with gout regarding information, communication, treatment and disease monitoring, and patients' views on and preferences for eHealth applications to address these needs.Methods: A focus group study using purposive sampling was conducted. Three focus group sessions with a duration of 2 h per group were held with in total of 23 patients using urate-lowering therapy, recruited from primary and secondary care. Audio recordings were transcribed, and data were analysed using thematic analysis.Results: Eight themes were identified. Five themes addressed support needs of gout patients and suitability of eHealth in addressing those needs: (1) Timely access to healthcare, especially during flares; (2) (personalized) information regarding diagnosis, medication, and diet; (3) insight into uric acid levels and medication side effects through blood monitoring; (4) better coordination across primary and secondary care; and (5) self-management and shared responsibility over care for maintaining health. Three themes addressed eHealth in general: (1) receptive towards eHealth in gout care; (2) the preference for eHealth to have a complementary role (i.e. not replacing face-to-face) contact with healthcare providers; and (3) preferences on eHealth use and functionalities.Conclusion: Patients expressed various needs regarding their disease management and projected a supporting role for eHealth in (self)management of gout. Addressing the needs and preferences of patients could enhance their understanding of the disease and treatment, self-management, and possibly health outcomes.","PeriodicalId":21350,"journal":{"name":"Rheumatology Advances in Practice","volume":"8 4","pages":"rkae125"},"PeriodicalIF":2.1,"publicationDate":"2024-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11494372/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142506996","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A case report of a rare form of calcium pyrophosphate disease: sacroiliitis with soft tissue involvement mimicking an infectious disease. 一份罕见焦磷酸钙病的病例报告：骶髂关节炎伴软组织受累，模仿传染病。

IF 2.1

Rheumatology Advances in Practice Pub Date : 2024-10-04 eCollection Date: 2024-01-01 DOI: 10.1093/rap/rkae123

Alexia Leloix, Marion Hervouet, Émilie Chotard, Raphael Guillin, Pascal Guggenbuhl, François Robin

引用次数: 0

Nerve pathology and cutaneous features of acute rheumatoid vasculitis. 急性类风湿血管炎的神经病理学和皮肤特征。

IF 2.1

Rheumatology Advances in Practice Pub Date : 2024-10-04 eCollection Date: 2024-01-01 DOI: 10.1093/rap/rkae124

Felipe J S Jones, Catherine Daley, Stephanie L Grach, Thomas G Mason, Marcus V Pinto

引用次数: 0

Oral health and dental care challenges in scleroderma-perspectives of dentists, rheumatologists and patients. 硬皮病患者的口腔健康和牙科护理挑战--牙科医生、风湿病学家和患者的观点。

IF 2.1

Rheumatology Advances in Practice Pub Date : 2024-10-03 eCollection Date: 2024-01-01 DOI: 10.1093/rap/rkae121

Tyler J Mills, Elizabeth Price, Vishal R Aggarwal, Francesco Del Galdo, Liz Walker

{"title":"Oral health and dental care challenges in scleroderma-perspectives of dentists, rheumatologists and patients.","authors":"Tyler J Mills, Elizabeth Price, Vishal R Aggarwal, Francesco Del Galdo, Liz Walker","doi":"10.1093/rap/rkae121","DOIUrl":"10.1093/rap/rkae121","url":null,"abstract":"Objectives: The oral healthcare challenges of people living with scleroderma are poorly understood, yet frequently reported. This mixed methods study aimed to investigate oral health and dental care challenges associated with scleroderma from the perspective of dentists, rheumatologists and patients.Methods: Dentists, rheumatologists and scleroderma patients in the UK completed a survey about their experiences of oral health, dental care and quality of life. People with scleroderma were also interviewed. We conducted descriptive analysis of quantitative data and used thematic analysis to examine qualitative data.Results: A total of 95.5% of patients reported oral and dental manifestations of scleroderma (ODMS); 57.1% reported high physical impacts, 53.8% high psychological impacts and 47.7% high social impacts. Only 13% of patients were informed of ODMS at diagnosis. No dentist or rheumatologist felt fully confident in managing ODMS. The most frequent suggestion for improvement among patients and dentists was increased information for dentists. We identified three key themes: significant negative impact on quality of life, barriers to accessing dental care and characteristics of good dental care.Conclusion: ODMS are prevalent issues, constituting a significant burden on quality of life. Rheumatologists should inform scleroderma patients of ODMS and embed oral health inquiries into annual reviews. Communication between medical and dental practitioners should be encouraged to facilitate early identification and management of ODMS.","PeriodicalId":21350,"journal":{"name":"Rheumatology Advances in Practice","volume":"8 4","pages":"rkae121"},"PeriodicalIF":2.1,"publicationDate":"2024-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11530228/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142569510","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0