Revista Panamericana De Salud Publica-pan American Journal of Public Health最新文献

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[Communicating Vaccine-related Events: Experiences with ESAVIComunicação de eventos relacionados a vacinas: experiências com ESAVI]. [疫苗相关事件的传播:ESAVI的经验]。
IF 2 4区 医学
Revista Panamericana De Salud Publica-pan American Journal of Public Health Pub Date : 2024-12-16 eCollection Date: 2024-01-01 DOI: 10.26633/RPSP.2024.78
Evelyn Carolina López Morales, Claudia Cerón Coral
{"title":"[Communicating Vaccine-related Events: Experiences with ESAVIComunicação de eventos relacionados a vacinas: experiências com ESAVI].","authors":"Evelyn Carolina López Morales, Claudia Cerón Coral","doi":"10.26633/RPSP.2024.78","DOIUrl":"10.26633/RPSP.2024.78","url":null,"abstract":"<p><p>The objective of this study was to analyze the role of risk communication in the response to cases of adverse events supposedly attributable to vaccination and immunization (ESAVI) in countries of the Americas.</p>","PeriodicalId":21264,"journal":{"name":"Revista Panamericana De Salud Publica-pan American Journal of Public Health","volume":"48 ","pages":"e78"},"PeriodicalIF":2.0,"publicationDate":"2024-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11648037/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142838870","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Challenges and strategies in the response to the measles outbreak during the COVID-19 Pandemic in Mexico, 25 Years after eliminationDesafios e estratégias na resposta ao surto de sarampo durante a pandemia de COVID-19 no México, 25 anos pós-eliminação]. [应对墨西哥COVID-19大流行期间爆发的措施的挑战和战略,消除25年后墨西哥COVID-19大流行期间麻疹爆发的挑战和战略,消除25年后]。
IF 2 4区 医学
Revista Panamericana De Salud Publica-pan American Journal of Public Health Pub Date : 2024-12-16 eCollection Date: 2024-01-01 DOI: 10.26633/RPSP.2024.77
Santa Elizabeth Ceballos-Liceaga, Nadia María Romualdo-Tello, Paulina Sánchez-Novoa, Luisa Sosa Laso, Guillermo Carbajal Sandoval, Edith Cruz-Ramírez, Kathia Landín-Martínez, Carolina Leriche-Ramírez, Herlinda García-Lozano, Irma López Martínez, Gabriel García-Rodríguez, Ruy López-Ridaura, José Luis Díaz Ortega
{"title":"[Challenges and strategies in the response to the measles outbreak during the COVID-19 Pandemic in Mexico, 25 Years after eliminationDesafios e estratégias na resposta ao surto de sarampo durante a pandemia de COVID-19 no México, 25 anos pós-eliminação].","authors":"Santa Elizabeth Ceballos-Liceaga, Nadia María Romualdo-Tello, Paulina Sánchez-Novoa, Luisa Sosa Laso, Guillermo Carbajal Sandoval, Edith Cruz-Ramírez, Kathia Landín-Martínez, Carolina Leriche-Ramírez, Herlinda García-Lozano, Irma López Martínez, Gabriel García-Rodríguez, Ruy López-Ridaura, José Luis Díaz Ortega","doi":"10.26633/RPSP.2024.77","DOIUrl":"10.26633/RPSP.2024.77","url":null,"abstract":"<p><strong>Objective: </strong>Identify the challenges that Mexico faced during the measles outbreak during the COVID-19 pandemic and describe the interventions to interrupt measles virus circulation.</p><p><strong>Methods: </strong>Descriptive, retrospective study of actions taken during the measles outbreak during the COVID-19 pandemic.</p><p><strong>Results: </strong>Epidemiological surveillance of febrile exanthematous diseases has been carried out continuously in the country since 1992. This measles outbreak demonstrated the limitations and strengths of the health system with respect to measles control in the context of a pandemic.</p><p><strong>Conclusions: </strong>A very important factor in controlling the outbreak was to strengthen the training and coordination of rapid response teams belonging to local health districts, states, the national network of government-operated public health laboratories, and the national laboratory supporting epidemiological surveillance (LAVE). On 31 August 2020, after 90 days of active surveillance and reports of negative test results from the network of health units and laboratory units, it was concluded that the country remained free of measles transmission.</p>","PeriodicalId":21264,"journal":{"name":"Revista Panamericana De Salud Publica-pan American Journal of Public Health","volume":"48 ","pages":"e77"},"PeriodicalIF":2.0,"publicationDate":"2024-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11648207/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142838584","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[High-quality Follow-up Measles and Rubella vaccination Campaign in Mexico, 2021Campanha de vacinação de seguimento de alta qualidade contra sarampo e rubéola no México, 2021]. [墨西哥麻疹和风疹疫苗高质量后续接种运动,2021年]
IF 2 4区 医学
Revista Panamericana De Salud Publica-pan American Journal of Public Health Pub Date : 2024-12-16 eCollection Date: 2024-01-01 DOI: 10.26633/RPSP.2024.111
José Luis Díaz-Ortega, Regina Durón-Andino, Cesar Omar Zuñiga-Ocampo, José Gerardo Rios-Castillo, Eva Román-Castro, Luis Humberto González-Ramírez, José Manasés Aguilar-Villaseñor, María Guadalupe Jacobo-Ramírez
{"title":"[High-quality Follow-up Measles and Rubella vaccination Campaign in Mexico, 2021Campanha de vacinação de seguimento de alta qualidade contra sarampo e rubéola no México, 2021].","authors":"José Luis Díaz-Ortega, Regina Durón-Andino, Cesar Omar Zuñiga-Ocampo, José Gerardo Rios-Castillo, Eva Román-Castro, Luis Humberto González-Ramírez, José Manasés Aguilar-Villaseñor, María Guadalupe Jacobo-Ramírez","doi":"10.26633/RPSP.2024.111","DOIUrl":"10.26633/RPSP.2024.111","url":null,"abstract":"<p><strong>Objective: </strong>To describe Mexico's experience of a high-quality follow-up vaccination campaign against measles and rubella in children aged 1 to 4 years, and actions taken to recover the coverage of other biologics during the COVID-19 health emergency.</p><p><strong>Method: </strong>Use of a microplanning tool in the design and implementation of a follow-up campaign to protect 8 604 781 girls and boys aged 1 to 4 years and to complete other vaccination schedules, followed by the implementation of rapid vaccination monitoring.</p><p><strong>Results: </strong>A total of 8 026 184 doses of MR vaccine were administered to children aged 1 to 4 years, with a coverage rate of 93.3%. In addition, 3 058 201 doses of MMR vaccine and 2 361 021 doses of hexavalent vaccine were administered. Rapid vaccination monitoring was carried out 78 times in selected municipalities in the country, where 30% (18 692) of 62 308 children aged 1-4 years contacted were found to be unvaccinated. The reasons for not vaccinating were \"not knowing it was necessary\" (28.5%), \"not having time\" (21.2%), \"other reasons\" (mainly fear of getting sick from COVID-19 in health centers) (12.9%), \"believing they had received two doses of MMR vaccine\" (9.1%), or \"not knowing where to get vaccinated\" (8.7%); 19.6% did not respond.</p><p><strong>Conclusions: </strong>The high-quality vaccination campaign was successful, favoring the sustainability of measles, rubella, and polio elimination, as well as the control of other vaccine-preventable diseases, and demonstrating the relevance of microplanning.</p>","PeriodicalId":21264,"journal":{"name":"Revista Panamericana De Salud Publica-pan American Journal of Public Health","volume":"48 ","pages":"e111"},"PeriodicalIF":2.0,"publicationDate":"2024-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11648098/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142839195","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Islands of data: cultivating an open data landscape for sustainable development in the Caribbean. 数据孤岛:为加勒比地区的可持续发展培育开放的数据景观。
IF 2 4区 医学
Revista Panamericana De Salud Publica-pan American Journal of Public Health Pub Date : 2024-12-16 eCollection Date: 2024-01-01 DOI: 10.26633/RPSP.2024.64
Ian R Hambleton, Selvi Jeyaseelan
{"title":"Islands of data: cultivating an open data landscape for sustainable development in the Caribbean.","authors":"Ian R Hambleton, Selvi Jeyaseelan","doi":"10.26633/RPSP.2024.64","DOIUrl":"10.26633/RPSP.2024.64","url":null,"abstract":"<p><p>The widespread digitization of information, advances in data processing and the emergence of internet-connected devices have led to a proliferation of data, often loosely referred to as big data. With this digital transformation, offering open data - that is, data freely available for modification and reuse - has emerged as a key strategy for encouraging transparency and innovation. Data reuse holds particular importance in the small island developing states of the Caribbean, which have a limited resource pool from which to tackle the landscape of social priorities. Efforts made towards data-sharing must consider privacy, security and the ethical use of information, and the tension between data as a social good and data for commercial gain can be a determinant of data-sharing decisions. A multidisciplinary approach is needed to realize the potential of data-sharing. In this article, we describe techniques (or pathways) for growing the Caribbean's stock of open data, classifying these into four types. Initiative pathways are techniques to broaden the range of data producers that share data. Infrastructure pathways deal with the practicalities of making data publicly available. Governance pathways are regulations and frameworks that guide data producers, including in meeting their legal data obligations. Training and communication pathways are efforts to raise awareness and knowledge about the benefits and practices of data-sharing. Data-sharing can offer a cost-effective evidence base for the Caribbean's continuing digital transformation. Sustainable sharing is key, and it must include robust technical infrastructure and governance, and ongoing communication.</p>","PeriodicalId":21264,"journal":{"name":"Revista Panamericana De Salud Publica-pan American Journal of Public Health","volume":"48 ","pages":"e64"},"PeriodicalIF":2.0,"publicationDate":"2024-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11648196/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142839320","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Digital transformation in Honduras: an information system for surveillance of ESAVI/AESITransformação digital em Honduras: sistema de informações para a vigilância de ESAVI/EAIE]. [洪都拉斯的数字化转型:ESAVI/AESIT 监测信息系统 洪都拉斯的数字化转型:ESAVI/EAIE 监测信息系统]。
IF 2 4区 医学
Revista Panamericana De Salud Publica-pan American Journal of Public Health Pub Date : 2024-12-16 eCollection Date: 2024-01-01 DOI: 10.26633/RPSP.2024.127
Sinya Yulibeth Núñez, Christian Ortiz, Ary Ávila, Nadia María Romualdo-Tello, Carlos Aguilar
{"title":"[Digital transformation in Honduras: an information system for surveillance of ESAVI/AESITransformação digital em Honduras: sistema de informações para a vigilância de ESAVI/EAIE].","authors":"Sinya Yulibeth Núñez, Christian Ortiz, Ary Ávila, Nadia María Romualdo-Tello, Carlos Aguilar","doi":"10.26633/RPSP.2024.127","DOIUrl":"10.26633/RPSP.2024.127","url":null,"abstract":"<p><p>In Honduras, health systems have been faced with a duty and a need to establish surveillance mechanisms in order to understand the pathways of health and disease in the population. The objective of this article is to describe the process of analysis and the strategies used during development of a robust information system for vaccine safety surveillance, which can also be replicated for other forms of surveillance. For this purpose, agile development methods and open-source tools were used to design and develop a baseline monitoring system, incorporating recognized standards for information coding, validation, and verification. This successful implementation of a reliable, stable, and scalable information system that will be used for the surveillance of events supposedly attributable to vaccination and immunization (ESAVI) and adverse events of special interest (AESI) should allow the timely and agile capture of surveillance data and facilitate data analysis.</p>","PeriodicalId":21264,"journal":{"name":"Revista Panamericana De Salud Publica-pan American Journal of Public Health","volume":"48 ","pages":"e127"},"PeriodicalIF":2.0,"publicationDate":"2024-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11648060/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142839137","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mining social media data to inform public health policies: a sentiment analysis case study. 挖掘社交媒体数据为公共卫生政策提供信息:一个情感分析案例研究。
IF 2 4区 医学
Revista Panamericana De Salud Publica-pan American Journal of Public Health Pub Date : 2024-12-16 eCollection Date: 2024-01-01 DOI: 10.26633/RPSP.2024.79
Suzana N Russell, Lila Rao-Graham, Maurice McNaughton
{"title":"Mining social media data to inform public health policies: a sentiment analysis case study.","authors":"Suzana N Russell, Lila Rao-Graham, Maurice McNaughton","doi":"10.26633/RPSP.2024.79","DOIUrl":"10.26633/RPSP.2024.79","url":null,"abstract":"<p><p>In the face of growing health challenges, nontraditional sources of data, such as open data, have the potential to transform how decisions are made and used to inform public health policies. Focusing on the COVID-19 pandemic, this article presents a case study employing sentiment analysis on unstructured social media data from Twitter (now X) to gauge public sentiment regarding pandemic-related restrictions. Our study aims to uncover and analyze Jamaican citizens' emotions and opinions surrounding COVID-19 restrictions following an outbreak at a call center in April 2020. Machine learning sentiment analysis was used to analyze tweets from Twitter related to the lockdown. A total of 1 609 tweets were retrieved and analyzed, 76% of which expressed negative sentiments, suggesting that the majority of citizens were not in favor of the restrictions. The low compliance with the government-mandated policy may be related to the high percentage of negative sentiments expressed. Insights from citizens' sentiments derived from open data sources such as Twitter can serve as valuable indicators for public health policymakers, providing critical input that will aid in tailoring interventions that align with public sentiments, thereby enhancing the effectiveness of and compliance with public health policies. This type of analysis can be useful to the health community and more generally to governments, as it allows for a more scientific assessment of public response to public health intervention techniques in real time. This study contributes to the emerging discourse on the integration of nontraditional data into public health policy-making, highlighting the growing potential for the use of these novel analytic techniques in addressing complex public health challenges.</p>","PeriodicalId":21264,"journal":{"name":"Revista Panamericana De Salud Publica-pan American Journal of Public Health","volume":"48 ","pages":"e79"},"PeriodicalIF":2.0,"publicationDate":"2024-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11648203/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142839338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Lessons for sustaining the elimination of measles, rubella, and congenital rubella syndrome in the Caribbean. 加勒比地区持续消除麻疹、风疹和先天性风疹综合征的经验教训。
IF 2 4区 医学
Revista Panamericana De Salud Publica-pan American Journal of Public Health Pub Date : 2024-12-16 eCollection Date: 2024-01-01 DOI: 10.26633/RPSP.2024.60
Tracy Evans-Gilbert, Karen Broome, Beryl Irons, Karen N Lewis-Bell, Elizabeth Ferdinand, J Peter Figueroa
{"title":"Lessons for sustaining the elimination of measles, rubella, and congenital rubella syndrome in the Caribbean.","authors":"Tracy Evans-Gilbert, Karen Broome, Beryl Irons, Karen N Lewis-Bell, Elizabeth Ferdinand, J Peter Figueroa","doi":"10.26633/RPSP.2024.60","DOIUrl":"10.26633/RPSP.2024.60","url":null,"abstract":"<p><p>This study searched grey literature and PubMed for strategies to sustain the elimination of measles, rubella, and congenital rubella syndrome and prevent their reintroduction in the Caribbean. Strategies were categorized at the macro, meso, and micro health levels. Macro strategies include: strong, clear, unified political and technical leadership and support; country ownership and subregional coordination of resources, policies, and programs; government investment in national immunization programs; and timely payment to the Pan American Health Organization Revolving Fund for affordable, good-quality vaccines. Including the private health sector and health workers in the tourism industry to identify and manage suspected imported cases, and finding and vaccinating every unvaccinated child, university student or frontline worker are key meso strategies. Strong social and communication programs are the key micro strategies needed to promote vaccine confidence and gain public trust. Priority macro strategies include a strengthened legislative framework supporting immunization, and policies to ring-fence the immunization budget, mitigate the rapid turnover of staff, and train new immunization managers. Establishing infrastructure to vaccinate adolescents and adults, including through the private sector, increasing the capacity to test for measles and rubella, and updating digital surveillance systems for timely decision-making are also critical meso strategies to prevent the reintroduction of these diseases. Partnerships, commitment, and collaborative efforts that contribute to elimination must be sustained, and health strategies strengthened to keep the Caribbean free of endemic transmission of measles, rubella, and congenital rubella syndrome.</p>","PeriodicalId":21264,"journal":{"name":"Revista Panamericana De Salud Publica-pan American Journal of Public Health","volume":"48 ","pages":"e60"},"PeriodicalIF":2.0,"publicationDate":"2024-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11648150/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142839324","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[A comprehensive approach to achieving reverification of measles elimination in Venezuela, 2019-2023Abordagem integral para a reverificação da eliminação do sarampo na Venezuela, 2019-2023]. [委内瑞拉2019-2023年实现消除麻疹措施复核的综合办法,2019-2023年委内瑞拉消除麻疹措施复核的综合办法]。
IF 2 4区 医学
Revista Panamericana De Salud Publica-pan American Journal of Public Health Pub Date : 2024-12-16 eCollection Date: 2024-01-01 DOI: 10.26633/RPSP.2024.102
Lesbia Muro, Luisa Castillo, Lieska Rodríguez, Pierina D'Angelo, Noraidys Porras, José Manuel García, Nuris Valderrama, Rosa Rodríguez, Neris Villalobos, Carlos Torres, Victoria Villavicencio
{"title":"[A comprehensive approach to achieving reverification of measles elimination in Venezuela, 2019-2023Abordagem integral para a reverificação da eliminação do sarampo na Venezuela, 2019-2023].","authors":"Lesbia Muro, Luisa Castillo, Lieska Rodríguez, Pierina D'Angelo, Noraidys Porras, José Manuel García, Nuris Valderrama, Rosa Rodríguez, Neris Villalobos, Carlos Torres, Victoria Villavicencio","doi":"10.26633/RPSP.2024.102","DOIUrl":"https://doi.org/10.26633/RPSP.2024.102","url":null,"abstract":"<p><strong>Objective: </strong>To describe the comprehensive activities implemented in the Bolivarian Republic of Venezuela to achieve reverification of measles elimination by 2023.</p><p><strong>Methods: </strong>Descriptive study of the procedures implemented to achieve reverification of measles elimination by 2023 according to the components set forth in the Regional Framework for the Monitoring and Re-verification of Measles, Rubella, and Congenital Rubella Syndrome Elimination in the Americas, published in 2022.</p><p><strong>Results: </strong>Due to a measles outbreak that began in epidemiological week (EW) 26 of 2017, Venezuela lost the elimination status which had been conferred in 2016 by the Expert Committee. Endemic transmission of the virus was reestablished in EW26 of 2018, after 12 months of circulation. After 111 weeks, 7054 confirmed cases and 80 deaths, endemic transmission was interrupted in EW33 2019; this prompted vaccination activities and intensified surveillance, in addition to securing financial resources for procurement of vaccines and supplies. Evidence of these activities was provided to the Measles and Rubella Elimination Regional Monitoring and Re-Verification Commission (RVC), which enabled the country to be reverified as measles-free by 2023.</p><p><strong>Conclusions: </strong>Venezuela achieved interruption of endemic measles transmission in 2019, and then carried out activities which enabled it to meet the core criteria for reverification of elimination as established in the Regional Framework.</p>","PeriodicalId":21264,"journal":{"name":"Revista Panamericana De Salud Publica-pan American Journal of Public Health","volume":"48 ","pages":"e102"},"PeriodicalIF":2.0,"publicationDate":"2024-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11648096/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142838654","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
High frequency of HPV high-risk preventable genotypes in Ecuadorian women with invasive cervical cancer. 厄瓜多尔浸润性宫颈癌妇女中HPV高危可预防基因型的高频率
IF 2 4区 医学
Revista Panamericana De Salud Publica-pan American Journal of Public Health Pub Date : 2024-12-04 eCollection Date: 2024-01-01 DOI: 10.26633/RPSP.2024.128
Gustavo David García Muentes, Fadi Abdul Latif, Claudia Catalina Beltrán Rodríguez, Sebastián Medina González, Juan Carlos Ruiz Cabezas
{"title":"High frequency of HPV high-risk preventable genotypes in Ecuadorian women with invasive cervical cancer.","authors":"Gustavo David García Muentes, Fadi Abdul Latif, Claudia Catalina Beltrán Rodríguez, Sebastián Medina González, Juan Carlos Ruiz Cabezas","doi":"10.26633/RPSP.2024.128","DOIUrl":"10.26633/RPSP.2024.128","url":null,"abstract":"<p><strong>Objective: </strong>To determine the distribution of human papillomavirus (HPV) genotypes in invasive cervical cancer samples from Ecuadorian women who attended the Cancer Institute (Sociedad de Lucha Contra el Cáncer - SOLCA).</p><p><strong>Methods: </strong>Archived formalin-fixed paraffin-embedded (FFPE) cervical cancer tissue samples collected during 2017-2021 were deparaffinized, and nucleic acid extraction and purification was performed using silica columns. The obtained nucleic acids were analyzed using INNO-LiPA® HPV Genotyping Extra II per the manufacturer's specifications. Data were retrieved from records, and HPV genotypes were determined from the FFPE samples.</p><p><strong>Results: </strong>The study included samples from 190 women diagnosed with invasive cervical cancer, with a median age of 52.78 years. Squamous cell carcinoma accounted for 78.94% of the cases, while 21.05% had adenocarcinoma. Among the 190 samples, 80.53% tested positive for HPV DNA, while 19.47% were negative. The most common genotypes detected were HPV 16 (64.05%), 18 (16.99%), and 58 (6.54%). HPV infection frequency was higher in samples from patients with elementary level education (<i>p</i> < 0.05).</p><p><strong>Conclusions: </strong>This study provides valuable insights into the distribution of HPV genotypes in invasive cervical cancer samples from Ecuadorian women. The results indicate an elevated presence of HPV 16, HPV 18, and HPV 58, which are vaccine-preventable genotypes.</p>","PeriodicalId":21264,"journal":{"name":"Revista Panamericana De Salud Publica-pan American Journal of Public Health","volume":"48 ","pages":"e128"},"PeriodicalIF":2.0,"publicationDate":"2024-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11616456/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142780989","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Effects of the COVID-19 pandemic on the immunization program for children under 5 years of age in EcuadorEfeitos da pandemia de COVID-19 no programa de imunização de menores de cinco anos no Equador]. [COVID-19大流行对厄瓜多尔5岁以下儿童免疫规划的影响]。
IF 2 4区 医学
Revista Panamericana De Salud Publica-pan American Journal of Public Health Pub Date : 2024-12-04 eCollection Date: 2024-01-01 DOI: 10.26633/RPSP.2024.134
Erick Antonio Osorio López, José Edmundo Urquieta-Salomón, Martí Alfaro Quevedo Pinos, José B Espinoza Suárez, Víctor Becerril-Montekio, Olga Elena Espinosa-Henao, Jacqueline Elizabeth Alcalde-Rabanal
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