Revista da Associacao Medica Brasileira最新文献_第5页

Comparison of hepatitis B surface antigen, anti-hepatitis B surface, and anti-hepatitis C virus prevalence in Syrian refugee pregnant women and Turkish pregnant women. 叙利亚难民孕妇和土耳其孕妇乙型肝炎表面抗原、抗乙型肝炎表面和抗丙型肝炎病毒流行率的比较

IF 1.4 4区医学

Revista da Associacao Medica Brasileira Pub Date : 2023-01-01 DOI: 10.1590/1806-9282.20221446

Kemal Hansu, Ismail Gurkan Cikim

{"title":"Comparison of hepatitis B surface antigen, anti-hepatitis B surface, and anti-hepatitis C virus prevalence in Syrian refugee pregnant women and Turkish pregnant women.","authors":"Kemal Hansu, Ismail Gurkan Cikim","doi":"10.1590/1806-9282.20221446","DOIUrl":"https://doi.org/10.1590/1806-9282.20221446","url":null,"abstract":"Objective: In this study, we aimed to determine and compare hepatitis B surface antigen level, anti-hepatitis B surface, and anti-hepatitis C virus positivity in Turkish pregnant women and Syrian refugee pregnant women residing in Turkey.Methods: The study was conducted on Syrian refugee pregnant women aged 15-45 years and Turkish pregnant women who applied to state hospital's gynecology and obstetrics outpatient clinics between April 30, 2012, and April 30, 2022. In our study, 136,376 pregnant women (104,629 Turkish and 31,747 Syrian) tested for hepatitis B surface antigen, 72,035 pregnant women (53,070 Turkish and 18,965 Syrian) tested for anti-hepatitis B surface, and 120,611 pregnant women (92,514 Turkish and 28,097 Syrian) tested for anti-hepatitis C virus were included. The patients were divided into six groups for hepatitis B surface antigen, anti-hepatitis B surface, and anti-hepatitis C virus results based on their age: <20 years, 20-24 years, 25-29 years, 30-34 years, 35-39 years, and >40 years. For each age group, the results of Syrian refugee pregnant women and Turkish pregnant women were compared.Results: Hepatitis B surface antigen positivity and anti-hepatitis B surface positivity were significantly higher in Turkish pregnant women compared to Syrian refugee pregnant women. Anti-hepatitis C virus positivity was significantly higher in Syrian refugee pregnant women compared to Turkish pregnant women.Conclusion: Based on the available data, we think that hepatitis B surface antigen, anti-hepatitis B surface, and anti-hepatitis C virus tests should be done routinely for pregnant women. Raising awareness among Syrian refugees about the hepatitis B virus vaccine as well as encouraging them to be vaccinated may reduce the negative impact of migration.","PeriodicalId":21234,"journal":{"name":"Revista da Associacao Medica Brasileira","volume":"69 6","pages":"e20221446"},"PeriodicalIF":1.4,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/3b/bc/1806-9282-ramb-69-06-e20221446.PMC10234357.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9936681","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Anesthesia and women's peculiarities. 麻醉和女人的特性。

IF 1.4 4区医学

Revista da Associacao Medica Brasileira Pub Date : 2023-01-01 DOI: 10.1590/1806-9282.2023S103

Luis Antonio Dos Santos Diego

引用次数: 0

Acupuncture for pregnancy-related pain in the lower back and posterior pelvic girdle. 针刺治疗腰背部及骨盆后带妊娠相关疼痛。

IF 1.4 4区医学

Revista da Associacao Medica Brasileira Pub Date : 2023-01-01 DOI: 10.1590/1806-9282.2023S101

Marcus Yu Bin Pai, Adriano Hohl, Luciano Ricardo Curuci de Souza, Mara Valeria Mendes, Luiz Carlos Souza Sampaio, Andre Wan Wen Tsai

{"title":"Acupuncture for pregnancy-related pain in the lower back and posterior pelvic girdle.","authors":"Marcus Yu Bin Pai, Adriano Hohl, Luciano Ricardo Curuci de Souza, Mara Valeria Mendes, Luiz Carlos Souza Sampaio, Andre Wan Wen Tsai","doi":"10.1590/1806-9282.2023S101","DOIUrl":"https://doi.org/10.1590/1806-9282.2023S101","url":null,"abstract":"INTRODUCTION Low back pain and pelvic pain are common conditions during pregnancy, and they can persist even after delivery1. The etiology of this phenomenon is complex, likely involving mechanical, circulatory, hormonal, and psychosocial factors2. Although there are no organic or specific diseases in most cases, the effects of pain can be considerable, negatively affecting sleep quality, physical condition, work performance, social life, and leisure activities, as well as leading to economic losses due to absenteeism1,3. The experience of pain during pregnancy is widespread, and its treatment poses significant challenges4. Some pain-relieving medications can pose dangers to both the fetus and the mother, while inadequate pain management can lead to severe maternal consequences such as depression and high blood pressure4. Due to limitations concerning pain management, acupuncture becomes an important treatment5. Acupuncture has been increasingly integrated into Western medicine as a complementary therapy for various conditions, especially pain, and has been shown to have analgesic, anti-inflammatory, and neuromodulatory effects6. Several studies have suggested that acupuncture can relieve pregnancy-related pain in the lower back and posterior pelvic girdle by improving blood circulation, relaxing muscles, reducing inflammation, and regulating hormones7–9.","PeriodicalId":21234,"journal":{"name":"Revista da Associacao Medica Brasileira","volume":"69 suppl 1","pages":"e2023S101"},"PeriodicalIF":1.4,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/9b/41/1806-9282-ramb-69-suppl1-e2023S101.PMC10411702.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10036587","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of pregnancy symptoms on the sexual quality of life. 妊娠症状对性生活质量的影响。

IF 1.4 4区医学

Revista da Associacao Medica Brasileira Pub Date : 2023-01-01 DOI: 10.1590/1806-9282.20230111

Esra Nur Çiftçi Mutlu, Funda Tosun Güleroğlu

{"title":"Effect of pregnancy symptoms on the sexual quality of life.","authors":"Esra Nur Çiftçi Mutlu, Funda Tosun Güleroğlu","doi":"10.1590/1806-9282.20230111","DOIUrl":"https://doi.org/10.1590/1806-9282.20230111","url":null,"abstract":"Objective: This descriptive cross-sectional study aimed to determine the effect of pregnancy symptoms on the sexual quality of life.Methods: This study included 150 pregnant women who visited the obstetrics and gynecology outpatient clinic of the hospital between October 1, 2019, and April 1, 2020, and met the inclusion criteria. Data were collected using the Personal and Obstetric Information form, Sexual Quality of Life-Female scale, and Pregnancy Symptom Inventory.Results: The mean age of the participants was 27.7±5.2 years. As per the collected data, 39.3% of the participants had university- or higher-level education and 21.3% had an income-generating job. A weak negative correlation was found between the scores of Sexual Quality of Life-Female and frequency of pregnancy symptoms and limitation in daily activities (p=0.016 and p=0.020, respectively), whereas a strong positive correlation was found between frequency of pregnancy symptoms and limitation in daily activities. Regression analysis showed that as Sexual Quality of Life-Female scores decreased, frequency of pregnancy symptoms and limitation in daily activities scores increased (p<0.001).Conclusion: Our study showed that, as the frequency of symptoms experienced during pregnancy and their impact on daily life increase, the sexual quality of life decreases. We recommend providing education and counseling services to women and their partners about pregnancy symptoms and its impact on sexual life during pregnancy and implementing effective measures to eliminate the negative effects of these symptoms on the sexual quality of life.","PeriodicalId":21234,"journal":{"name":"Revista da Associacao Medica Brasileira","volume":"69 8","pages":"e20230111"},"PeriodicalIF":1.4,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/62/1e/1806-9282-ramb-69-08-e20230111.PMC10427179.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10046776","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

What do patients know about healthcare-associated infections? What do they want to know? Ethical evaluation. 患者对医疗保健相关感染了解多少?他们想知道什么?道德评价。

IF 1.4 4区医学

Revista da Associacao Medica Brasileira Pub Date : 2023-01-01 DOI: 10.1590/1806-9282.20230292

Pervin Sahiner

{"title":"What do patients know about healthcare-associated infections? What do they want to know? Ethical evaluation.","authors":"Pervin Sahiner","doi":"10.1590/1806-9282.20230292","DOIUrl":"https://doi.org/10.1590/1806-9282.20230292","url":null,"abstract":"Introduction: Patients hospitalized for treatment may be exposed to healthcare-associated infections, and these infections can affect patients seriously.Objective: This research was conducted to determine what hospitalized patients know and what they want to know about healthcare-associated infections.Methods: This is a full-text original research article. The study was conducted between July and September 2022 with inpatients in all clinics of Kocaeli University Hospital in Turkey. A total of 310 patients participated in this cross-sectional study. The questions were asked by the researcher and the answers were recorded.Results: Almost all (92.8%) the patients who stated that they knew what healthcare-associated infection was evaluated their knowledge as insufficient. Patients with higher educational levels have more information (p=0.000) about healthcare-associated infections. Young (p=0.000) and highly educated patients (p=0.000) stated that the infection rate of the hospital would affect the choice of hospital.Conclusion: Patients want to learn about healthcare-associated infections, but most do not know about them. Patients should be informed about healthcare-associated infections during hospitalization planning and hospitalization.","PeriodicalId":21234,"journal":{"name":"Revista da Associacao Medica Brasileira","volume":"69 8","pages":"e20230292"},"PeriodicalIF":1.4,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/49/34/1806-9282-ramb-69-08-e20230292.PMC10427178.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10046779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Decreased growth differentiation factor 9, bone morphogenetic protein 15, and forkhead box O3a expressions in the ovary via ulipristal acetate. 通过醋酸乌普利司酯降低卵巢中生长分化因子9、骨形态发生蛋白15和叉头盒O3a的表达。

IF 1.4 4区医学

Revista da Associacao Medica Brasileira Pub Date : 2023-01-01 DOI: 10.1590/1806-9282.20230381

Damla Gül Fındık, Gülnur Take Kaplanoğlu, Gökçe Nur Arık, Nagwa Bugumaa Abubaker Alemari

{"title":"Decreased growth differentiation factor 9, bone morphogenetic protein 15, and forkhead box O3a expressions in the ovary via ulipristal acetate.","authors":"Damla Gül Fındık, Gülnur Take Kaplanoğlu, Gökçe Nur Arık, Nagwa Bugumaa Abubaker Alemari","doi":"10.1590/1806-9282.20230381","DOIUrl":"https://doi.org/10.1590/1806-9282.20230381","url":null,"abstract":"Objective: Folliculogenesis is a complex process involving various ovarian paracrine factors. During folliculogenesis, vitamin D3 and progesterone are significant for the proper development of follicles. This study aimed to investigate the effects of vitamin D3 and selective progesterone receptor modulator ulipristal acetate on ovarian paracrine factors.Methods: In the study, 18 female Wistar-albino rats were randomly divided into three groups: control group (saline administration, n=6), vitamin D3 group (300 ng/day vitamin D3 oral administration, n=6), and UPA group (3 mg/kg/day ulipristal acetate oral administration, n=6). Ovarian tissue was analyzed by histochemistry and immunohistochemistry. For quantification of immunohistochemistry, the mean intensities of growth differentiation factor 9, bone morphogenetic protein 15, and forkhead box O3a expressions were measured by Image J and MATLAB. Blood samples were collected for the analysis of serum anti-Müllerian hormone levels by ELISA.Results: Atretic follicles and hemorrhagic cystic structures were observed in the UPA group. After immunohistochemistry via folliculogenesis assessment markers, growth differentiation factor 9, bone morphogenetic protein 15, and cytoplasmic forkhead box O3a expressions decreased in the UPA group (p<0.05). Anti-Müllerian hormone level did not differ significantly between the experimental groups (p>0.05).Conclusion: Ulipristal acetate negatively affects folliculogenesis via ovarian paracrine factors. The recommended dietary vitamin D3 supplementation in healthy cases did not cause a significant change.","PeriodicalId":21234,"journal":{"name":"Revista da Associacao Medica Brasileira","volume":"69 8","pages":"e20230381"},"PeriodicalIF":1.4,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/dd/49/1806-9282-ramb-69-08-e20230381.PMC10427182.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10048809","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Does resveratrol reduce cisplatin-induced ovarian damage? 白藜芦醇能减轻顺铂引起的卵巢损伤吗?

IF 1.4 4区医学

Revista da Associacao Medica Brasileira Pub Date : 2023-01-01 DOI: 10.1590/1806-9282.20230314

Baris Ciplak, Eyup Gokhan Turmus, Ozlem Kara, Gulcin Daglioglu, Mehmet Murat Altindag, Yavuz Simsek, Yusuf Kenan Daglioglu, Mustafa Kara

{"title":"Does resveratrol reduce cisplatin-induced ovarian damage?","authors":"Baris Ciplak, Eyup Gokhan Turmus, Ozlem Kara, Gulcin Daglioglu, Mehmet Murat Altindag, Yavuz Simsek, Yusuf Kenan Daglioglu, Mustafa Kara","doi":"10.1590/1806-9282.20230314","DOIUrl":"https://doi.org/10.1590/1806-9282.20230314","url":null,"abstract":"SUMMARY OBJECTIVE: The objective of this study was to investigate the protectiveness of resveratrol on cisplatin-induced damage to the ovary using experimental models. METHODS: A total of 30 female Wistar-Albino rats constituted the research material. The rats were categorized into three groups: Group 1 was administered one milliliter of 0.9% NaCl solution, Group 2 was administered 7.5 mg/kg cisplatin, and Group 3 was administered 7.5 mg/kg cisplatin and 10 mg/kg resveratrol. Ovaries were extirpated in all groups and subjected to biochemical and histopathological tests. Cisplatin-induced damage to ovarian tissue was graded and scored as the total histopathological findings score. The ovarian function was assessed using immunohistochemical staining for c-kit expression. Rats’ malondialdehyde, catalase, and superoxide dismutase levels were determined. RESULTS: The histopathological finding score was significantly higher in Group 2 than in other groups (p<0.05). The superoxide dismutase and catalase levels were significantly higher in Group 3 than in Group 2 (p<0.001 for both cases). The malondialdehyde level was significantly higher in Group 2 than in Group 3 (p<0.001). CONCLUSION: The study findings demonstrated that resveratrol reduced ovarian injury and enhanced biochemical parameters following cisplatin-induced ovary damage in experimental models.","PeriodicalId":21234,"journal":{"name":"Revista da Associacao Medica Brasileira","volume":"69 8","pages":"e20230314"},"PeriodicalIF":1.4,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/e7/b3/1806-9282-ramb-69-08-e20230314.PMC10427173.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10048812","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comments on "Evaluation of functional parameters of the foot and ankle in elderly with sarcopenia". 对“老年肌肉减少症患者足、踝功能参数的评价”的评论。

IF 1.4 4区医学

Revista da Associacao Medica Brasileira Pub Date : 2023-01-01 DOI: 10.1590/1806-9282.20230583

Cassius Iury Anselmo-E-Silva, Leticia Menegalli Santos, André Luiz Lopes, Erika da Silva Maciel, Fernando Rodrigues Peixoto Quaresma, Aldair Darlan Santos-de-Araújo, André Pontes-Silva

{"title":"Comments on \"Evaluation of functional parameters of the foot and ankle in elderly with sarcopenia\".","authors":"Cassius Iury Anselmo-E-Silva, Leticia Menegalli Santos, André Luiz Lopes, Erika da Silva Maciel, Fernando Rodrigues Peixoto Quaresma, Aldair Darlan Santos-de-Araújo, André Pontes-Silva","doi":"10.1590/1806-9282.20230583","DOIUrl":"https://doi.org/10.1590/1806-9282.20230583","url":null,"abstract":"The paper title does not contain this information 1 , but Souza Júnior et al. 1 identified sarcopenic elderly people through the SARC-F score and grip-force strength using a Jamar dyna-mometer. Traditionally, the Jamar dynamometer is the reference standard tool for grip-force strength evaluations with excellent validity and reliability in the clinic and research 2,3 , and many health professionals use it for measuring grip-force strength and recording a single maximal or submaximal grip-force strength value during testing 2,3 . Nevertheless, the Jamar dynamometer is a mechanical measurement tool and only shows instantaneous grip-force strength, which means that it cannot continuously record handgrip force or show changes in the quality of grip-force strength control. The Jamar dynamometer also needs recalibration each year 4 , and a study reported that its limited contact area may cause hand pain in subjects, thereby influencing the grip-force measurement when applying higher grip strength 5,6 . Souza Júnior et al. 1 did not report these adjustments.","PeriodicalId":21234,"journal":{"name":"Revista da Associacao Medica Brasileira","volume":"69 8","pages":"e20230583"},"PeriodicalIF":1.4,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/56/94/1806-9282-ramb-69-08-e20230583.PMC10427175.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10048816","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Video-based digital platforms as an educational resource for the surgical preparation of orthopedic surgeons. 基于视频的数字平台作为骨科医生手术准备的教育资源。

IF 1.4 4区医学

Revista da Associacao Medica Brasileira Pub Date : 2023-01-01 DOI: 10.1590/1806-9282.20230205

Hakan Zeybek, Hakan Cici, Ali Ihsan Kilic

{"title":"Video-based digital platforms as an educational resource for the surgical preparation of orthopedic surgeons.","authors":"Hakan Zeybek, Hakan Cici, Ali Ihsan Kilic","doi":"10.1590/1806-9282.20230205","DOIUrl":"https://doi.org/10.1590/1806-9282.20230205","url":null,"abstract":"Objective: The aim of the study was to research the video-based digital platforms that orthopedic specialists in Turkey use as an educational resource in their surgical preparations that they have not seen or done before, the frequency of their use of these platforms, and their trust in these platforms, with a survey study.Methods: The importance of video-based digital platforms in surgical preparations that surgeons have not seen or done before was measured using the data obtained from 181 orthopedic specialists using a survey prepared on an Internet-based server (docs.google.com).Results: Orthopedists used video-based digital platforms with a ratio of 38.7% among the educational resources in their surgical preparations that they have not seen or done before. There was no significant difference between the specialists with a surgical experience of 1-10 years and more than 10 years of experience in terms of using video-based digital platforms in surgical preparation (p>0.05). A total of 81.2% of the participants used only video-based digital platforms in the preparation of a surgical procedure they have never seen before. The most frequently used digital platform was YouTube, and 62% of the participants considered these platforms reliable.Conclusion: Orthopedic specialists in Turkey primarily and frequently use video-based digital platforms as a training resource in their preparations for surgery that they have not seen or done before. The establishment or support of platforms with evidence-based content with references from official orthopedic institutions and organizations can increase the trust of orthopedic specialists in these platforms.","PeriodicalId":21234,"journal":{"name":"Revista da Associacao Medica Brasileira","volume":"69 7","pages":"e20230205"},"PeriodicalIF":1.4,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/e2/31/1806-9282-ramb-69-07-e20230205.PMC10352006.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9841894","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Vascular endothelial growth factor gene insertion/deletion polymorphism is associated with Vitamin D level in Turkish patients with coronavirus disease 2019. 2019年土耳其冠状病毒病患者血管内皮生长因子基因插入/缺失多态性与维生素D水平相关

IF 1.4 4区医学

Revista da Associacao Medica Brasileira Pub Date : 2023-01-01 DOI: 10.1590/1806-9282.20221713

Serbulent Yigit, Sengul Tural, Recai Aci, Ozlem Sezer

{"title":"Vascular endothelial growth factor gene insertion/deletion polymorphism is associated with Vitamin D level in Turkish patients with coronavirus disease 2019.","authors":"Serbulent Yigit, Sengul Tural, Recai Aci, Ozlem Sezer","doi":"10.1590/1806-9282.20221713","DOIUrl":"https://doi.org/10.1590/1806-9282.20221713","url":null,"abstract":"Objective: Coronavirus disease 2019 emerges as a disease caused by severe acute respiratory syndrome coronavirus 2. It is a systemic disease associated with vascular inflammation and endothelial damage. In this study, we aimed to investigate whether vascular endothelial growth factor gene insertion/deletion polymorphism is associated with coronavirus disease 2019 in the Turkish population.Methods: The study included 179 participants (79 patients with coronavirus disease 2019 and 100 controls). DNA isolation was made from peripheral blood, and then the polymerase chain reaction analysis was performed.Results: When we analyze vascular endothelial growth factor gene insertion/deletion polymorphism in the study group, we found that the DD genotype and D allele were found to be statistically significantly different when compared to coronavirus disease 2019 patients with high vitamin D value (p=0.005 for DD genotype and p=0.006 for D allele) in the control group. In this high-level control group, when we analyze II+ID genotype versus DD, a statistically significant difference was also detected (p=0.007).Conclusion: As a result of the study, we found that DD genotype and D allele were associated with vitamin D level in Turkish patients with coronavirus disease 2019.","PeriodicalId":21234,"journal":{"name":"Revista da Associacao Medica Brasileira","volume":"69 7","pages":"e20221713"},"PeriodicalIF":1.4,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/ae/c2/1806-9282-ramb-69-07-e20221713.PMC10352018.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9847551","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0