Korean Journal of Pediatric Gastroenterology and Nutrition最新文献_第2页

A Case of Neonatal Gastric Ulcer with Large Hematoma Presenting as Gastric Outlet Obstruction 新生儿胃溃疡合并大血肿表现为胃出口梗阻1例

Korean Journal of Pediatric Gastroenterology and Nutrition Pub Date : 2011-12-01 DOI: 10.5223/KJPGN.2011.14.4.398

J. Kim, E. J. Shim, Kwangwoo Lee

引用次数: 0

Diagnostic Yield of Pediatric Colonoscopies Based on Presenting Symptoms in a Secondary Hospital 某二级医院儿童结肠镜检查基于表现症状的诊断率

Korean Journal of Pediatric Gastroenterology and Nutrition Pub Date : 2011-12-01 DOI: 10.5223/KJPGN.2011.14.4.368

Y. Cho, I. Cho, H. Yoo, Hwang Choi, Bo-In Lee, Sang Yong Kim, D. Jeong, S. Chung, J. Kang

{"title":"Diagnostic Yield of Pediatric Colonoscopies Based on Presenting Symptoms in a Secondary Hospital","authors":"Y. Cho, I. Cho, H. Yoo, Hwang Choi, Bo-In Lee, Sang Yong Kim, D. Jeong, S. Chung, J. Kang","doi":"10.5223/KJPGN.2011.14.4.368","DOIUrl":"https://doi.org/10.5223/KJPGN.2011.14.4.368","url":null,"abstract":"Purpose: We performed this study retrospectively to review the diagnostic yield of colonoscopies in children and adolescents with various gastrointestinal symptoms and to investigate the relationship between presenting symptoms and the colonoscopic findings in a secondary hospital. Methods: We reviewed the medical records of patients under the age of 19-years who underwent ileocolonoscopy between January 2001 and December 2010. The total number of patients (n=238) were divided into three age groups and six symptom groups. We analyzed clinical characteristics and the colonoscopic findings, and compared the colonoscopic yield between each groups. Results: The median age of the patients was 16.1 (3.1∼18.9) years. The most common presenting symptoms were lower gastrointestinal (GI) bleeding (48.1%) in the ≤12 years group (n=27), chronic abdominal pain (31.8%) in the 13∼15 years group (n=85), and chronic diarrhea (34.9%) in the ≥16 years group (n=126). Positive colonoscopic findings were found in 21.4% of the bowel habit change group (n=28), 51.9% of the low GI bleeding group (n=54), 37.7% of the chronic diarrhea group (n=69), and 94.4% of the group with suspected inflammatory bowel disease (IBD) (n=18), 38.9% of the chronic abdominal pain group (n=54) and 13.3% of the anemia group (n=15). The diagnostic yield of the total examination was 42.0%. The suspected IBD group had a higher yield than the presenting symptom groups (p＜0.001). Conclusion: Colonoscopy is a safe and useful investigation in children and adolescents with suspected colonic disease. The diagnostic yield of colonoscopy is higher in patients presenting with suspected IBD. Pediatricians practicing in primary or secondary care settings should recommend colonoscopy for patients with suspected IBD. (Korean J Pediatr Gastroenterol Nutr 2011; 14: 368∼375)","PeriodicalId":212346,"journal":{"name":"Korean Journal of Pediatric Gastroenterology and Nutrition","volume":"34 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2011-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132168944","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

The Characteristics and Diagnostic Methods of Food Protein Induced Proctocolitis 食物蛋白性直肠炎的特点及诊断方法

Korean Journal of Pediatric Gastroenterology and Nutrition Pub Date : 2011-12-01 DOI: 10.5223/KJPGN.2011.14.SUPPL1.S47

A. Kim, J. Hwang

{"title":"The Characteristics and Diagnostic Methods of Food Protein Induced Proctocolitis","authors":"A. Kim, J. Hwang","doi":"10.5223/KJPGN.2011.14.SUPPL1.S47","DOIUrl":"https://doi.org/10.5223/KJPGN.2011.14.SUPPL1.S47","url":null,"abstract":"Food protein induced proctocolitis (FPIPC) is a non-IgE mediated food allergy. FPIPC occurs exclusively among breast-fed infants within the first months of life. FPIPC is often diagnosed clinically in normal-conditioned infants with rectal bleeding. But FPIPC among infancy with rectal bleeding is less general than conceived. The endoscopic findings reveal an edematous and erythematous mucosa with superficial erosions or ulcerations, bleeding and lymphoid nodular hyperplasia. The prominent eosinophilic infiltrates in the rectosigmoid mucosa are important for the histopathologic diagnosis of FPIPC. However, in explaining eosinophilic infiltration within the lamina propria of the mucosa, it is necessary to differentiate whether it is a part of normal findings or occurs due to inflammatory reactions. Oral food challenge and elimination test is performed to identify the same clinical reaction as the symptom of FPIPC by the administration of a specific type of food to infants. The most common causal food is cow’s milk. Thus oral food challenge and elimination test can be the effective way of confirming FPIPC, reducing the possibility of misdiagnosis. The purpose of this report is to identify the characteristics of FPIPC, to introduce its diagnostic methods, and to suggest the future direction of research. (Korean J Pediatr Gastroenterol Nutr 2011; 14(Suppl 1): S47∼S54)","PeriodicalId":212346,"journal":{"name":"Korean Journal of Pediatric Gastroenterology and Nutrition","volume":"112 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2011-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130020555","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Helicobacter pylori Infection and Extraintestinal Manifestations in Children 儿童幽门螺杆菌感染与肠外表现

Korean Journal of Pediatric Gastroenterology and Nutrition Pub Date : 2011-12-01 DOI: 10.5223/KJPGN.2011.14.SUPPL1.S1

J. Park, J. Seo, H. Youn, Hyung‐Lyun Kang, S. Baik, Woo-Kon Lee, M. Cho, K. Rhee

{"title":"Helicobacter pylori Infection and Extraintestinal Manifestations in Children","authors":"J. Park, J. Seo, H. Youn, Hyung‐Lyun Kang, S. Baik, Woo-Kon Lee, M. Cho, K. Rhee","doi":"10.5223/KJPGN.2011.14.SUPPL1.S1","DOIUrl":"https://doi.org/10.5223/KJPGN.2011.14.SUPPL1.S1","url":null,"abstract":"Helicobacter pylori (H. pylori) may be one of the most common pathogen in gastrointestinal tract. Although several recent articles have reported a decline in the prevalence of H. pylori infection in both children and adults over the last several years, H. pylori infection usually occurs early in life and persists for a long time. The role of H. pylori in some digestive diseases, such as gastritis, ulcer and gastric cancer has been well established. And the possible role of H. pylori as a trigger for some extraintestinal diseases in children and adults has been considered in the last year. H. pylori infection might be associated with refractory iron deficiency anemia, idiopathic thrombocytopenic purpura, growth retardation and obesity etc, directly or indirectly. Most of the studies are classified as epidemiological, clinical researches about effects on extraintestinal manifestations after eradication, or case reports. This review describes the possibility of association with several extraintestinal diseases and H. pylori infection and their possible mechanisms based on reported studies in the world and our several studies, even though there are still many conflicting results about that. (Korean J Pediatr Gastroenterol Nutr 2011; 14(Suppl 1): S1∼S8)","PeriodicalId":212346,"journal":{"name":"Korean Journal of Pediatric Gastroenterology and Nutrition","volume":"39 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2011-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124048496","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Stem Cell in Pediatric Gastrointestinal Tract Disease: Hirschsprung Disease 干细胞在儿童胃肠道疾病中的作用:巨结肠疾病

Korean Journal of Pediatric Gastroenterology and Nutrition Pub Date : 2011-12-01 DOI: 10.5223/KJPGN.2011.14.SUPPL1.S42

S. Bae

引用次数: 0

Breakfast and Health in Adolescents 青少年的早餐与健康

Korean Journal of Pediatric Gastroenterology and Nutrition Pub Date : 2011-12-01 DOI: 10.5223/KJPGN.2011.14.4.340

Kie Young Park

引用次数: 15

A Child with Abdominal Pain, Headache, and Dizziness 儿童腹痛、头痛、头晕

Korean Journal of Pediatric Gastroenterology and Nutrition Pub Date : 2011-12-01 DOI: 10.5223/KJPGN.2011.14.SUPPL1.S19

K. Lee

引用次数: 0

Nonalcoholic Fatty Liver Disease in Children 儿童非酒精性脂肪性肝病

Korean Journal of Pediatric Gastroenterology and Nutrition Pub Date : 2011-09-01 DOI: 10.5223/KJPGN.2011.14.3.209

J. Seo

{"title":"Nonalcoholic Fatty Liver Disease in Children","authors":"J. Seo","doi":"10.5223/KJPGN.2011.14.3.209","DOIUrl":"https://doi.org/10.5223/KJPGN.2011.14.3.209","url":null,"abstract":"Obesity is significantly increasing in Korean adolescents and nonalcoholic fatty liver disease (NAFLD) is soon expected to be the most common chronic liver disease in children. The symptoms of NAFLD run a broad spectrum and NAFLD in children can lead to the development of nonalcoholic steatohepatitis, cirrhosis and end-stage liver disease, hepatocellular carcinoma (HCC), and can increases the risk of type 2 diabetes and cardiovascular disease. Definitive diagnosis can be achieved with liver biopsy. However, recent advances have shown alternative methods of screening and following patients with noninvasive biomarkers and radiologic imaging studies. The histopathology differs between children and adults, and the mechanism is expected to differ as well. Several factors, such as genes and environmental stressors work intricately to produce NAFLD. Promising medications have been reported for the management of NAFLD. However, their therapeutic effectiveness has yet to be determined. Dietary and exercise interventions remain the mainstay of treatment. By maintaining an interest in obesity and NALFD in children, NAFLD should be diagnosed early and appropriate lifestyle changes should be counseled and encouraged. (Korean J Pediatr Gastroenterol Nutr 2011; 14: 209∼221)","PeriodicalId":212346,"journal":{"name":"Korean Journal of Pediatric Gastroenterology and Nutrition","volume":"11 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2011-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122514289","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Organic Upper Digestive Diseases in Children with Chronic Abdominal Pain 慢性腹痛患儿的器质性上消化道疾病

Korean Journal of Pediatric Gastroenterology and Nutrition Pub Date : 2011-09-01 DOI: 10.5223/KJPGN.2011.14.3.232

S. Chang

{"title":"Organic Upper Digestive Diseases in Children with Chronic Abdominal Pain","authors":"S. Chang","doi":"10.5223/KJPGN.2011.14.3.232","DOIUrl":"https://doi.org/10.5223/KJPGN.2011.14.3.232","url":null,"abstract":"Organic diseases are prevalent in about 5 to 10% of children with chronic abdominal pain. The most common diseases of the upper digestive tract include gastroesophageal reflux disease (GERD), chronic gastritis with or without Helicobacter pylori (H. pylori), and peptic ulcer. The H. pylori infections acquired during childhood persist lifelong without eradication. Although the majority of H. pylori infected children remain asymptomatic, H. pylori infection may cause various digestive and extra-digestive diseases. There are still debates about a causal relationship between H. pylori-gastritis and abdominal symptoms in the absence of peptic ulcer disease. The number of Korean children infected with antibiotic resistant H. pylori is increasing even though the prevalence decreases after eradication. The choices of rescue therapy are limited in children after eradication failure. Antioxidant supplements with regimens against H. pylori have been tried with limited effects. Here I wanted to review the findings of recent reports on common upper digestive diseases such as GERD, peptic ulcer, and H. pylori infection in children with chronic abdominal pain. (Korean J Pediatr Gastroenterol Nutr 2011; 14: 232∼244)","PeriodicalId":212346,"journal":{"name":"Korean Journal of Pediatric Gastroenterology and Nutrition","volume":"8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2011-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121853034","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

FOXP3+T Cells and TGF-β1 in Colonic Mucosa of Children with Crohn's Disease 克罗恩病患儿结肠黏膜FOXP3+T细胞及TGF-β1的变化

Korean Journal of Pediatric Gastroenterology and Nutrition Pub Date : 2011-09-01 DOI: 10.5223/KJPGN.2011.14.3.258

J. Gil, J. Oh, J. Seo, M. Cho, K. Cho, E. Yoo

{"title":"FOXP3+T Cells and TGF-β1 in Colonic Mucosa of Children with Crohn's Disease","authors":"J. Gil, J. Oh, J. Seo, M. Cho, K. Cho, E. Yoo","doi":"10.5223/KJPGN.2011.14.3.258","DOIUrl":"https://doi.org/10.5223/KJPGN.2011.14.3.258","url":null,"abstract":"Purpose: Forkhead box protein 3 (FOXP3)+T cells are the major regulatory T cells controlling all aspects of the immune response. Transforming growth factor-β (TGF-β) is a suppressive cytokine which mediates the suppressive action of FOXP3+T cells. The aim of this study was to investigate the role of FOXP3+T cells, TGF-β in colonic mucosa of children with Crohn’s disease (CD). Methods: Colonic mucosal biopsies were obtained from 10 children with CD (12∼15 years of age) and 11 control (8∼15 years of age). Frequencies of FOXP3+T, CD4+T cells and TGF-β1 expression were examined in the lamina propria (LP) and lymphoid aggregates or follicles (LA/F) by immunohistochemistry, and later evaluated by association with disease activity. Results: In the LP of CD group, frequencies of FOXP3+T, CD4+T cells, proportion of FOXP3/CD4+T cells and TGF-β1 expression significantly increased compared to the control. In the LA/F of CD group, frequency of FOXP3+T cells, proportion of FOXP3/CD4+T cells and TGF-β1 expression significantly increased compared to the control (p＜0.05). CD4+T cells also increased compared to the control, but this finding was not significant. In the LP and LA/F of CD group, frequency of FOXP3+T cells exhibited positive correlation with CD4+T cells (p＜0.05). In the LP and LA/F of CD group, TGF-β1 expression had positive correlation with CRP, Pediatric Crohn's Disease Activity Index, and negative correlation with hematocrit and albumin (p＜0.05). Conclusion: Increased frequency of FOXP3+T cells and TGF-β1 expression in colonic mucosa of CD can be interpreted as a compensatory increase towards achieving down-regulation of immune responses. (Korean J Pediatr Gastroenterol Nutr 2011; 14: 258∼268)","PeriodicalId":212346,"journal":{"name":"Korean Journal of Pediatric Gastroenterology and Nutrition","volume":"130 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2011-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131266708","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2