RetinaPub Date : 2024-05-02DOI: 10.1097/iae.0000000000004143
Milena Cioana, Sumana Naidu, P. M. Far, Shanna C. Yeung, Yuyi You, Peng Yan
{"title":"Post-intravitreal injection and post-cataract extraction endophthalmitis visual outcomes by organism: A systematic review and meta-analysis","authors":"Milena Cioana, Sumana Naidu, P. M. Far, Shanna C. Yeung, Yuyi You, Peng Yan","doi":"10.1097/iae.0000000000004143","DOIUrl":"https://doi.org/10.1097/iae.0000000000004143","url":null,"abstract":"\u0000 \u0000 To compare visual outcomes of endophthalmitis following intravitreal injections (IVI) and cataract extraction (CE) by causative organism.\u0000 \u0000 \u0000 \u0000 Searches in Cochrane Central Register of Controlled Trials, MEDLINE, and Embase identified articles reporting visual outcome by causative organism in post-IVI and CE endophthalmitis cases from January 2010-February 2022. A random-effects meta-analysis compared visual improvement amongst endophthalmitis cases by causative organism.\u0000 \u0000 \u0000 \u0000 85 out of 3317 retrieved studies were included. The highest degree of VA improvement in both post-IVI and post-CE endophthalmitis was seen in cases caused by coagulase-negative staphylococci (CONS), followed by gram-negative organisms, and other gram-positive organisms such as streptococci and enterococci. Culture negative cases showed more VA improvement than culture positive cases in post-IVI endophthalmitis. These results remained consistent when accounting for endophthalmitis treatment, IVI type, condition requiring IVI treatment, follow-up period and initial pre-procedural VA.\u0000 \u0000 \u0000 \u0000 CONS and gram-negative organisms show the most VA improvement in both post-IVI and post-CE endophthalmitis. Other gram-positive organisms such as streptococci and enterococci are associated with less visual improvement. This updated systematic review and meta-analysis reveals that the results of the Endophthalmitis Vitrectomy Study are consistent decades later despite advancements to surgical practices and evolution of microorganisms over time.\u0000","PeriodicalId":21178,"journal":{"name":"Retina","volume":"12 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141022599","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
RetinaPub Date : 2024-05-01DOI: 10.1097/iae.0000000000004130
Chunming Chen, Yan Shao, Hong Zhong, Chengyao Qin, Zehao Liu, Wenxiu Sun, Min Li
{"title":"A novel custom bent 27G needle-guided suture snare technique for scleral fixation of posterior chamber intraocular lenses","authors":"Chunming Chen, Yan Shao, Hong Zhong, Chengyao Qin, Zehao Liu, Wenxiu Sun, Min Li","doi":"10.1097/iae.0000000000004130","DOIUrl":"https://doi.org/10.1097/iae.0000000000004130","url":null,"abstract":"\u0000 \u0000 To describe a custom bent 27G needle-guided suture snare technique for scleral fixation of posterior chamber intraocular lenses (PCIOL).\u0000 \u0000 \u0000 \u0000 An 8-0 polypropylene suture was threaded into the lumen of a custom bent 27G needle, and the needle tip was advanced into the eye from the IOL fixation point. The suture was threaded through the posterior limbal incision inside the IOL haptic loop and pulled out. The needle tip was advanced into the eye again, going around the IOL haptic loop through the same limbal incision. The suture was threaded in again, and the needle was withdrawn from the eye, completing fixation of the IOL haptic loop. The suture knot was buried in the stroma of the sclera.\u0000 \u0000 \u0000 \u0000 The technique was performed in 10 eyes of 10 patients, with a preoperative logarithm of the minimum resolution angle corrected visual acuity of 0.73 ± 0.55 (Snellen 20/107), improvement of 0.24 ± 0.27 (Snellen 20/35) at the final follow-up visit, and a mean postoperative PCIOL tilt of 2.78 ± 1.32°. There were no cases of pupillary capture or suture-related complications during follow-up.\u0000 \u0000 \u0000 \u0000 The curved needle-guided suture snare technique provides a simple minimally-invasive method of scleral suture fixation of PCIOL.\u0000","PeriodicalId":21178,"journal":{"name":"Retina","volume":"21 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141025688","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
RetinaPub Date : 2024-04-12DOI: 10.1097/iae.0000000000004124
Min-Woo Lee, Ji-Ho Jun, Hwa-Young Yu, Jung-Tae Kim, Yong-Yeon Song
{"title":"The Superficial and Deep Vascular Complexes are Damaged to Different Extents in Advanced Stages of Diabetic Retinopathy","authors":"Min-Woo Lee, Ji-Ho Jun, Hwa-Young Yu, Jung-Tae Kim, Yong-Yeon Song","doi":"10.1097/iae.0000000000004124","DOIUrl":"https://doi.org/10.1097/iae.0000000000004124","url":null,"abstract":"\u0000 \u0000 To identify the extent of damage to the superficial vascular complex (SVC) and deep vascular complex (DVC) as the stage of diabetic retinopathy (DR) increases.\u0000 \u0000 \u0000 \u0000 Subjects were divided into four groups: patients with type 2 diabetes without DR (Group 1), those with mild to moderate nonproliferative DR (NPDR) (Group 2), those with severe to very severe NPDR (Group 3), and those with proliferative DR (PDR) (Group 4). The vessel densities (VDs) of the SVC (SVD) and DVC (DVD) and their ratios were compared. Linear regression analyses were used to identify factors associated with the SVD/DVD ratio.\u0000 \u0000 \u0000 \u0000 The SVDs were 25.5 ± 6.1, 25.1 ± 7.0, 24.5 ± 9.0, and 21.6 ± 6.9 % (P = 0.048); the DVDs 25.6 ± 5.3, 23.0 ± 7.0, 22.3 ± 8.8, and 17.5 ± 5.0 % (P < 0.001); and the SVD/DVD ratios 1.00 ± 0.16, 1.12 ± 0.20, 1.14 ± 0.33, and 1.24 ± 0.27 (P < 0.001) in Groups 1-4, respectively. In multivariate analysis, DR severity (B = 7.16, P < 0.001) and the HbA1c level (B = 1.57, P = 0.042) were significantly associated with the SVD/DVD ratio.\u0000 \u0000 \u0000 \u0000 Both the SVD and DVD tended to decrease in the advanced stages of DR, and the SVD/DVD ratio increased, indicating more severe damage to the DVC than the SVC. The ratio was positively associated with the HbA1c level, indicating a significant relationship between that level and DVD rather than SVD damage.\u0000","PeriodicalId":21178,"journal":{"name":"Retina","volume":"42 S2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140709919","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
RetinaPub Date : 2024-04-12DOI: 10.1097/iae.0000000000004127
Maki Okubo, Fukutaro Mano, Ryuya Hashimoto, T. Maeno, Kazuki Kuniyoshi, Shunji Kusaka
{"title":"Amalric triangular sign and carotid Doppler ultrasonographic findings in central retinal artery occlusion","authors":"Maki Okubo, Fukutaro Mano, Ryuya Hashimoto, T. Maeno, Kazuki Kuniyoshi, Shunji Kusaka","doi":"10.1097/iae.0000000000004127","DOIUrl":"https://doi.org/10.1097/iae.0000000000004127","url":null,"abstract":"\u0000 \u0000 This study aimed to determine the incidence of the Amalric triangular sign (ATS) in patients with central retinal artery occlusion (CRAO) and investigate its association with visual function and carotid Doppler ultrasonography findings.\u0000 \u0000 \u0000 \u0000 A retrospective chart review was conducted on 21 eyes from 21 cases with complete CRAO. Best-corrected visual acuity (BCVA) and carotid Doppler ultrasonography findings [peak systolic velocity (PSV), end-diastolic velocity (EDV), and resistance index (RI) = (PSV-EDV)/PSV] were investigated.\u0000 \u0000 \u0000 \u0000 Three patients (14%) exhibited the ATS. BCVA at first visit was significantly worse in ATS-positive than in ATS-negative (P = 0.024). Doppler waveform analysis of the common carotid artery (CCA) showed that ATS-positive patients had a significantly lower EDV [P = 0.009, median 10 (range 9–10) vs. 17 (13–24) m/s] and significantly higher RI [P = 0.021, median 0.80 (range 0.79–0.83) vs. 0.72 (0.66–0.82)] than did ATS-negative.\u0000 \u0000 \u0000 \u0000 The ATS was observed in three patients with CRAO, who showed worse BCVA at the first visit than did those without the ATS. Carotid Doppler ultrasonography revealed that ATS-positive patients had a significantly higher RI and lower EDV at the CCA than did ATS-negative, indicating steno-occlusive changes in the internal carotid artery.\u0000","PeriodicalId":21178,"journal":{"name":"Retina","volume":"20 12","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140710200","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
RetinaPub Date : 2024-04-12DOI: 10.1097/iae.0000000000004132
Bita Momenaei, Saagar A. Pandit, Kristine Wang, Taku Wakabayashi, Jason Hsu, C. Regillo, M. Klufas, David Xu, Michael Cohen, Sunir J. Garg, Ajay E Kuriyan, Yoshihiro Yonekawa
{"title":"Suprachoroidal Triamcinolone Acetonide for Refractory Postoperative Cystoid Macular Edema","authors":"Bita Momenaei, Saagar A. Pandit, Kristine Wang, Taku Wakabayashi, Jason Hsu, C. Regillo, M. Klufas, David Xu, Michael Cohen, Sunir J. Garg, Ajay E Kuriyan, Yoshihiro Yonekawa","doi":"10.1097/iae.0000000000004132","DOIUrl":"https://doi.org/10.1097/iae.0000000000004132","url":null,"abstract":"\u0000 \u0000 To investigate outcomes of suprachoroidal triamcinolone acetonide (SCS-TA; XIPERE, Bausch+Lomb) for the treatment of refractory postoperative cystoid macular edema (CME).\u0000 \u0000 \u0000 \u0000 Medical records of patients receiving SCS-TA for postoperative CME were reviewed. Primary outcomes were visual acuity (VA) and central foveal thickness (CFT).\u0000 \u0000 \u0000 \u0000 We included 32 eyes from 32 patients with median (interquartile range, IQR) follow-up duration of 6 (2-7) months and 1 (1-2) SCS-TA injection. 19 (59.4%) had a history of vitrectomy. The median (IQR) CFT decreased from 492 (379-629) µm to 267 (187-388) µm at 1 month (P<0.001), 362 (218-521) µm at 3 months (P=0.005), and 339 (206-514) µm at the final visit (P<0.001). Median logMAR VA improved from 0.65 (0.48-0.97, 20/89) at baseline to 0.54 (0.35-0.88, 20/69) (P=0.058) at 1 month, 0.54 (0.33-0.84, 20/69) at 3 months (P=0.121), and 0.60 (0.33-0.88, 20/80) at the final visit (P=0.021). Vitrectomized eyes had similar findings. Six eyes (18.8%) developed elevated intraocular pressure (IOP) (> 24 mmHg) (range: 25-49 mmHg) with a median IOP elevation of 13.5 mmHg compared to baseline, and all had prior glaucoma or ocular hypertension.\u0000 \u0000 \u0000 \u0000 SCS-TA reduced macular edema and improved vision in refractory postoperative CME, including vitrectomized eyes. IOP should be monitored, especially in those with a history of glaucoma or ocular hypertension.\u0000","PeriodicalId":21178,"journal":{"name":"Retina","volume":"117 13","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140708763","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
RetinaPub Date : 2024-04-08DOI: 10.1097/iae.0000000000004118
Sophie Frank, G. Reiter, Oliver Leingang, Philipp Fuchs, Leonard M. Coulibaly, Virginia Mares, H. Bogunović, U. Schmidt-Erfurth
{"title":"Advances in Photoreceptor and Retinal pigment epithelium Quantifications in intermediate AMD: High-Res versus Standard SPECTRALIS OCT","authors":"Sophie Frank, G. Reiter, Oliver Leingang, Philipp Fuchs, Leonard M. Coulibaly, Virginia Mares, H. Bogunović, U. Schmidt-Erfurth","doi":"10.1097/iae.0000000000004118","DOIUrl":"https://doi.org/10.1097/iae.0000000000004118","url":null,"abstract":"\u0000 \u0000 In this study we investigated differences in retinal feature visualization of high-resolution optical coherence tomography (OCT) devices with different axial resolutions in quantifications of retinal pigment epithelium (RPE) and photoreceptors (PR) in intermediate age-related macular degeneration (iAMD).\u0000 \u0000 \u0000 \u0000 Patients were imaged with standard SPECTRALIS HRA+OCT and the investigational High-Res OCT device (both by Heidelberg Engineering, Heidelberg, Germany). Drusen, RPE and PR layers were segmented using validated AI-based algorithms followed by manual corrections. Thickness- and drusen maps were computed for all patients. Loss and thickness measurements were compared between devices, drusen vs. non-drusen areas and EDTRS subfields using mixed-effects models.\u0000 \u0000 \u0000 \u0000 Thirty-three eyes from 28 iAMD patients were included. Normalized PR integrity loss was significantly higher with 4.6% for standard OCT compared to 2.5% on High-Res OCT. The central and parafoveal PR integrity loss was larger than perifoveal loss (p<0.05). PR thickness was increased on High-Res OCT and in non-drusen regions (p<0.001). RPE appeared thicker on standard OCT and above drusen (p<0.01).\u0000 \u0000 \u0000 \u0000 Our study shows that High-Res OCT is able to identify the condition of investigated layers in iAMD with higher precision. This improved in vivo imaging technology might promote our understanding of the pathophysiology and progression of AMD.\u0000","PeriodicalId":21178,"journal":{"name":"Retina","volume":"1 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140728736","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
RetinaPub Date : 2024-04-04DOI: 10.1097/iae.0000000000004125
T. Rossi, G. Querzoli, Pamela Cosimi, G. Ripandelli, L. Placentino, David H Steel, Mario R. Romano
{"title":"Three-Dimensional Retinal Displacement Before and After Macular Pucker Surgery","authors":"T. Rossi, G. Querzoli, Pamela Cosimi, G. Ripandelli, L. Placentino, David H Steel, Mario R. Romano","doi":"10.1097/iae.0000000000004125","DOIUrl":"https://doi.org/10.1097/iae.0000000000004125","url":null,"abstract":"\u0000 \u0000 To measure the coronal and sagittal retinal displacement before and after surgery for epiretinal membranes in InfraRed (IR) horizontal foveal sections and Optical Coherence Tomography (OCT) scans and describe displacement tridimensionality, vison loss and metamorphopsia.\u0000 \u0000 \u0000 \u0000 Retrospective series with greater than 6-month average follow-up before and after surgery. Record included best-corrected visual acuity (BCVA), OCT, M-charts, IR retinography. Overall, pre- and post-operative coronal and sagittal retinal displacement across the entire field, concentric circles at 0.5, 1.5 and 4.5mm radii and the central horizontal and vertical meridian were calculated as the optical flow of consecutive images.\u0000 \u0000 \u0000 \u0000 The study comprised 10 patients (4M, 6F), with 22.7±25.2 months follow-up before surgery and 16.2±7.3 months after. BCVA reduced before surgery (0.15±0.67 logMAR to 0.38±0.85 logMAR; p<0.05) and increased afterwards (0.086±0.61 logMAR; p=0.003). Pre-operative coronal displacement was 30.1±29.1 µm versus 67.0±23.4µm after (p=0.002). Sagittal retinal displacement was 140.9±84.6 µm before surgery, 339.7±172.5 µm after (p=0.017), and 357.6±320.8 µm across the entire follow-up. Pre-operative BCVA decrease correlated to the foveal coronal displacement. Vertical metamorphopsia correlated to the average coronal displacement within 4.5mm radius. Pre- and post-operative sagittal displacement correlated to horizontal metamorphopsia (p=0.006 and p=0.026). Post-operative sagittal displacement correlated with post-operative BCVA (p=0.026) and foveal thickness (p=0.009).\u0000 \u0000 \u0000 \u0000 The study confirms that post-operative displacement is greater than pre-operative and that sagittal displacement is greater than coronal and correlates with BCVA and metamorphopsia changes.\u0000","PeriodicalId":21178,"journal":{"name":"Retina","volume":"23 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140742105","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
RetinaPub Date : 2024-04-04DOI: 10.1097/iae.0000000000004126
Zhenping Li, Fan Yang, Xiaowen Deng, Yao Yang, Haijun Gong, Yuqing Lan
{"title":"ASSOCIATIONS BETWEEN CHOROIDAL ALTERATIONS AND EARLY NEURODEGENERATION IN DIABETES WITHOUT DIABETIC RETINOPATHY: INSIGHTS FROM ULTRA-WIDEFIELD OCTA IMAGING","authors":"Zhenping Li, Fan Yang, Xiaowen Deng, Yao Yang, Haijun Gong, Yuqing Lan","doi":"10.1097/iae.0000000000004126","DOIUrl":"https://doi.org/10.1097/iae.0000000000004126","url":null,"abstract":"\u0000 \u0000 To identify associations between choroidal alterations and the reduction of peripapillary retinal nerve fiber layer (pRNFL) thickness in diabetes without diabetic retinopathy (non-diabetic retinopathy, NDR).\u0000 \u0000 \u0000 \u0000 This retrospective cross-sectional study included 143 eyes from 83 NDR patients and 124 eyes from 82 matched healthy controls. Ultra-widefield swept-source optical coherence tomography angiography was used to automatically measure retinal and choroidal thickness (ChT), retinal vascular density, and choroidal vascular metrics. Data were analyzed using Student t-tests, generalized estimating equations and generalized linear mixed models.\u0000 \u0000 \u0000 \u0000 NDR patients exhibited significant reductions in perifoveal ChT (e.g., perifoveal inferior region: 253.42 ± 86.59μm vs. 281.01 ± 80.25μm, P = 0.026 in GEE-test) compared to the controls. The NDR group showed significant decrease in the choroidal vascular index (P = 0.012 in GEE-test), and increase in the choroidal stromal index (P = 0.012 in GEE-test). The average pRNFL thickness significantly decreased in NDR patients (114.58 ± 11.88μm vs. 120.25 ± 16.36μm, P = 0.005 in GEE-test). The thickness of outer nuclear layer (ONL) and total retina significantly decreased in NDR patients (P < 0.05). In multivariate models, ChT was sigficantly correlated with pRNFL thickness (β = 0.041, P = 0.001), even after adjusting by confounding factors (β = 0.056, P = 0.001).\u0000 \u0000 \u0000 \u0000 In NDR, there were decreases in ChT, choroidal vascular index, pRNFL thickness and ONL thickness. The reduction in ChT was independently associated with the reduction in pRNFL thickness, suggesting that ChT could serve as a predictor of retinal neurodegeneration in NDR.\u0000","PeriodicalId":21178,"journal":{"name":"Retina","volume":"52 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140742064","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
RetinaPub Date : 2024-04-03DOI: 10.1097/iae.0000000000004115
David M. Brown, Stephen Laswell, Effie Rahman, Kenneth C Fan, Ankoor R. Shah, Sagar Patel, C. Wykoff
{"title":"Clinically Relevant Posterior Vitreous Detachment Staging Using Circumpapillary and Macular Volume Optical Coherence Tomography","authors":"David M. Brown, Stephen Laswell, Effie Rahman, Kenneth C Fan, Ankoor R. Shah, Sagar Patel, C. Wykoff","doi":"10.1097/iae.0000000000004115","DOIUrl":"https://doi.org/10.1097/iae.0000000000004115","url":null,"abstract":"\u0000 \u0000 This study was designed to investigate retinal nerve fiber layer (RNFL) circumpapillary optical coherence tomography (C-OCT) to determine posterior vitreous detachment (PVD) status and to develop a clinically relevant PVD grading scale based on RNFL C-OCT to determine the incidence of PVD by age and association with vitreomacular traction disorders.\u0000 \u0000 \u0000 \u0000 Ophthalmic images and medical records of retina patients were retrospectively analyzed by three masked graders using RNFL C-OCT and macular OCT (M-OCT). Based on PVD status, eyes were categorized into five newly defined PVD stages.\u0000 \u0000 \u0000 \u0000 Among 2002 eyes, PVD stages were: A) 25 (1.25%); B) 725 (36.21%); C-) 248 (12.39%); C+) 151 (7.54%); D) 851 (42.51%); X) 2 (0.1%). PVD was correlated with advanced age (P<<0.0001). Limited separation or partial separation between lamella within the posterior vitreous cortex (stage B) was noted early (68% of eyes <18 years). 34% of eyes >70 years did not exhibit complete PVD. Of 75 eyes with tractional vitreoretinal disorders, 64 (85.3%) were stage C-/C+, identifying stage C as the high risk “complication” stage.\u0000 \u0000 \u0000 \u0000 Imaging analyses using RNFL C-OCT and M-OCT scans in conjunction allows rapid assessment of PVD stage. These techniques can assist clinicians and surgeons in counseling patients and planning surgical approach. Observations confirmed progression of PVD through predictable stages and progression of PVD with age.\u0000","PeriodicalId":21178,"journal":{"name":"Retina","volume":"1015 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140749323","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}