RetinaPub Date : 2024-07-03DOI: 10.1097/iae.0000000000004205
Navid Johannigmann-Malek, Danilo Iannetta, Yalin Zheng, Stephen B Kaye, Sofia Groselli, Katharina Kirchmair, Nikolaos Dervenis, Peter Charbel Issa, Carmen Baumann
{"title":"OCT features associated with vitreomacular traction release and macular hole size progression following treatment with ocriplasmin","authors":"Navid Johannigmann-Malek, Danilo Iannetta, Yalin Zheng, Stephen B Kaye, Sofia Groselli, Katharina Kirchmair, Nikolaos Dervenis, Peter Charbel Issa, Carmen Baumann","doi":"10.1097/iae.0000000000004205","DOIUrl":"https://doi.org/10.1097/iae.0000000000004205","url":null,"abstract":"\u0000 \u0000 To evaluate OCT features for vitreomacular traction (VMT) release and change in macular hole (MH) size after treatment with ocriplasmin.\u0000 \u0000 \u0000 \u0000 Patients who had undergone treatment with ocriplasmin for VMT with or without MH ≤400µm were included. Main outcomes were VMT release, and changes in minimum linear diameter (MLD) MH size at 4 weeks in MHs that persisted. OCT features evaluated were central retinal thickness, vitreomacular adhesion length, posterior vitreous cortex (PVC) insertion angles 500µm from the insertion points and MLD size.\u0000 \u0000 \u0000 \u0000 Sixty patients were included, 37 had isolated VMT and 23 VMT with a MH. Four weeks after ocriplasmin injection the overall VMT release rate was 66.7% (40/60); 64.9% (24/37) in eyes with isolated VMT and 69.6% (16/23) in eyes with MH. VMT release was associated with younger age (p=0.02). MH closure was achieved in 26.1% (6/23) and was associated with a smaller ratio of the temporal to the nasal PVC angle (p<0.01). Of the 17 persistent MHs, 76.5% (13/17) increased in MLD size from baseline 186 (±78) to 358 (±133) µm (p<0.001). Progression in MLD size showed a negative linear association with the size of the nasal PVC angle (R2=0.39, p=0.002), and a positive linear association with the ratio of the temporal to nasal PVC angle (R2=0.39, p=0.002).\u0000 \u0000 \u0000 \u0000 In patients with VMT associated MHs, the risk of MH enlargement following ocriplasmin is negatively correlated with the nasal PVC angle size and is increased if the ratio of the temporal to nasal angle is >1.\u0000","PeriodicalId":21178,"journal":{"name":"Retina","volume":"38 s171","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141683286","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
RetinaPub Date : 2024-07-03DOI: 10.1097/iae.0000000000004198
K. Ishikawa, Shintaro Nakao, Kenichiro Mori, Yosuke Fukuda, Kohei Kiyohara, Yuta Yasaka, Kodai Yuge, Shoji Notomi, Koh-hei Sonoda
{"title":"Fluid aspiration from intraretinal cysts for refractory diabetic macular edema","authors":"K. Ishikawa, Shintaro Nakao, Kenichiro Mori, Yosuke Fukuda, Kohei Kiyohara, Yuta Yasaka, Kodai Yuge, Shoji Notomi, Koh-hei Sonoda","doi":"10.1097/iae.0000000000004198","DOIUrl":"https://doi.org/10.1097/iae.0000000000004198","url":null,"abstract":"\u0000 \u0000 To report the surgical outcome of fluid aspiration in intraretinal cysts as a novel treatment approach for the refractory cystoid macular edema (CME) associated with diabetic retinopathy.\u0000 \u0000 \u0000 \u0000 This retrospective consecutive case series examined eight patients with refractory CME who underwent intraretinal cyst fluid aspiration using a 38-gauge subretinal infusion needle during pars plana vitrectomy. We reviewed changes in central retinal thickness (CRT), best-corrected visual acuity (BCVA), and central sensitivity among patients followed up for 12 months post-surgery.\u0000 \u0000 \u0000 \u0000 CRT on optical coherence tomography (μm) significantly improved at 12 months post-surgery (308 ± 99) compared to before surgery (480 ± 141) (P < 0.005). During the follow-up period, CME relapsed in one eye. The BCVA (logarithm of the minimal angle of resolution) at 12 months post-surgery (0.23 ± 0.32, Snellen equivalent: 20/50) was significantly better than the preoperative BCVA (0.39 ± 0.29, Snellen equivalent: 20/63) (P < 0.01). The mean deviation value of central sensitivity did not significantly change between preoperative (-2.5 ± 2.1) and postoperative (-2.2 ± 2.2) assessments (P = 0.07).\u0000 \u0000 \u0000 \u0000 Fluid aspiration in intraretinal cysts may be a treatment option for refractory CME in eyes with diabetes.\u0000","PeriodicalId":21178,"journal":{"name":"Retina","volume":" 16","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141681152","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
RetinaPub Date : 2024-07-03DOI: 10.1097/iae.0000000000004200
Shilpa Viswanath, Manu Sharma, Ramandeep Singh
{"title":"A novel technique of use of piece of 25 G infusion cannula as a sleeve for securing ends of 240 bands in encircling procedure","authors":"Shilpa Viswanath, Manu Sharma, Ramandeep Singh","doi":"10.1097/iae.0000000000004200","DOIUrl":"https://doi.org/10.1097/iae.0000000000004200","url":null,"abstract":"","PeriodicalId":21178,"journal":{"name":"Retina","volume":" 14","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141680823","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
RetinaPub Date : 2024-07-03DOI: 10.1097/iae.0000000000004197
F. Kalaw, Jesse Most, Rasha Nabil Kako, Paripoorna Sharma, Juan D. Arias, Jimmy S. Chen, Andrew C. Lin, Evan Walker, Dirk-Uwe G. Bartsch, Sally L. Baxter, Henry Ferreyra, William R. Freeman, S. Borooah
{"title":"Retinal structural changes after cessation of pentosan polysulfate sodium","authors":"F. Kalaw, Jesse Most, Rasha Nabil Kako, Paripoorna Sharma, Juan D. Arias, Jimmy S. Chen, Andrew C. Lin, Evan Walker, Dirk-Uwe G. Bartsch, Sally L. Baxter, Henry Ferreyra, William R. Freeman, S. Borooah","doi":"10.1097/iae.0000000000004197","DOIUrl":"https://doi.org/10.1097/iae.0000000000004197","url":null,"abstract":"\u0000 \u0000 To quantify baseline and longitudinal structural changes post-cessation in pentosan polysulfate sodium (PPS) retinopathy patients.\u0000 \u0000 \u0000 \u0000 This is a retrospective cohort study. Retinal thickness and volume of choroidal and hyperreflective retinal pigment epithelium (RPE) excrescences were manually segmented from optical coherence tomography (OCT) volume scans. Baseline measurements were compared against age-matched controls. Longitudinal measurements were performed on patients with follow-up data.\u0000 \u0000 \u0000 \u0000 Twenty-four eyes of 13 patients were included. At baseline, the mean total retinal thickness was lower in the PPS retinopathy cohort than in age and sex-matched controls (269.1 µm vs. 290.2 µm, p = 0.006).\u0000 The median (range) of follow-up was 18.6 (4.1 to 34.7) months, with the mean last follow-up of 35.2 months after cessation. During the follow-up period, the thickness of the retina decreased significantly by 11.3 µm (CI: 16.8, 5.8) (p<0.001), with an annual mean decrease of 6.70 µm. However, the mean hyperreflective RPE excrescence volume did not change significantly (p = 0.140) over the follow-up period.\u0000 \u0000 \u0000 \u0000 Following PPS discontinuation, although RPE excrescence volumes do not change significantly in volume, there continues to be a progressive long-term thinning of the retina which continues at a rate greater than that associated with normal aging. Consequently, long-term follow-up is suggested to monitor patients with PPS maculopathy.\u0000","PeriodicalId":21178,"journal":{"name":"Retina","volume":"74 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141682422","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
RetinaPub Date : 2024-07-03DOI: 10.1097/iae.0000000000004204
Seyyedehfatemeh Ghalibafan, David J. Taylor Gonzalez, Louis Z Cai, Brandon Graham Chou, Sugi Panneerselvam, Spencer Conrad Barrett, Mak B. Djulbegovic, Nicolas A. Yannuzzi
{"title":"“Applications of Multimodal Generative AI in a Real-World Retina Clinic Setting”","authors":"Seyyedehfatemeh Ghalibafan, David J. Taylor Gonzalez, Louis Z Cai, Brandon Graham Chou, Sugi Panneerselvam, Spencer Conrad Barrett, Mak B. Djulbegovic, Nicolas A. Yannuzzi","doi":"10.1097/iae.0000000000004204","DOIUrl":"https://doi.org/10.1097/iae.0000000000004204","url":null,"abstract":"\u0000 \u0000 Evaluate a large language model, GPT4 with vision (GPT-4V), for diagnosing vitreoretinal diseases in real-world ophthalmology settings.\u0000 \u0000 \u0000 \u0000 A retrospective cross-sectional study at Bascom Palmer Eye Clinic, analyzing patient data from January 2010 to March 2023, assesses GPT-4V’s performance on retinal image analysis and ICD-10 coding across two patient groups: simpler cases (Group A) and complex cases (Group B) requiring more in-depth analysis. Diagnostic accuracy was assessed through open-ended (OEQ) and multiple-choice questions (MCQs) independently verified by three retina specialists.\u0000 \u0000 \u0000 \u0000 In 256 eyes from 143 patients, GPT4-V demonstrated a 13.7% accuracy for OEQs and 31.3% for MCQs, with ICD-10 code accuracies at 5.5% and 31.3% respectively. Accurately diagnosed posterior vitreous detachment, non-exudative age-related macular degeneration, and retinal detachment. ICD-10 coding was most accurate for non-exudative age-related macular degeneration, central retinal vein occlusion, and macular hole in EOQs, and for posterior vitreous detachment, non-exudative age-related macular degeneration, and retinal detachment in MCQs. No significant difference in diagnostic or coding accuracy was found in Groups A and B.\u0000 \u0000 \u0000 \u0000 GPT-4V has potential in clinical care and record-keeping, particularly with standardized questions. Its effectiveness in open-ended scenarios is limited, indicating a significant limitation in providing complex medical advice.\u0000","PeriodicalId":21178,"journal":{"name":"Retina","volume":"69 1‐2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141682086","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
RetinaPub Date : 2024-07-03DOI: 10.1097/iae.0000000000004199
John Yu Cheng, J. Ben Margines, Neda Abraham, Irena Tsui, David Sarraf
{"title":"Blue Rubber Bleb Nevus Syndrome and Retinal Cavernous Hemangioma","authors":"John Yu Cheng, J. Ben Margines, Neda Abraham, Irena Tsui, David Sarraf","doi":"10.1097/iae.0000000000004199","DOIUrl":"https://doi.org/10.1097/iae.0000000000004199","url":null,"abstract":"","PeriodicalId":21178,"journal":{"name":"Retina","volume":"9 12","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141681362","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
RetinaPub Date : 2024-07-03DOI: 10.1097/iae.0000000000004203
Kathleen R Schildroth, Kyle D Peterson, Michael M Altaweel, R. Channa, Jonathan S Chang, Justin L Gottlieb, Michael S. Ip, T. M. Nork
{"title":"Supplemental Dextrose in the Infusion Fluid during Diabetic Vitrectomy","authors":"Kathleen R Schildroth, Kyle D Peterson, Michael M Altaweel, R. Channa, Jonathan S Chang, Justin L Gottlieb, Michael S. Ip, T. M. Nork","doi":"10.1097/iae.0000000000004203","DOIUrl":"https://doi.org/10.1097/iae.0000000000004203","url":null,"abstract":"\u0000 \u0000 Historically, supplemental dextrose to infusion fluid has been used to reduce the need for intraoperative lensectomies to maintain visualization during diabetic vitrectomy. Valved, small-gauge vitrectomy has reduced surgical time and decreased intraoperative fluid flow. Assessment of supplemental dextrose in modern vitrectomy is presented here.\u0000 \u0000 \u0000 \u0000 Retrospective cohort study of diabetic patients undergoing vitrectomy. The dextrose group received supplemental dextrose in the infusion fluid, while the nondextrose group used standard balanced salt solution (BSS Plus). Group assignment was per surgeons’ typical practice patterns. Eyes with tractional retinal detachments were also evaluated as a subgroup.\u0000 \u0000 \u0000 \u0000 330 phakic eyes were included. Supplemental dextrose was used in 199 eyes (60.3%). One unplanned lensectomy was performed in this series, in the nondextrose group, not statistically different from the dextrose group, with zero lensectomies (p = 0.4). Cataract survival curves overlapped for all eyes and for the tractional retinal detachment subgroup.\u0000 \u0000 \u0000 \u0000 In modern vitrectomy, unplanned lensectomy is rare. No difference was observed in the rate of intraoperative lensectomies or overall postoperative cataract course with or without dextrose supplementation to the infusion fluid. Standard solutions appear to be adequate for infusion, even for diabetics.\u0000","PeriodicalId":21178,"journal":{"name":"Retina","volume":"49 s170","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141682523","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
RetinaPub Date : 2024-06-12DOI: 10.1097/iae.0000000000004180
G. Baltă, I. Tofolean, Tamara Tiu, Valentin Dinu, Cristina-Mihaela Alexandrescu, Florian N Baltă, Liliana-Mary Voinea
{"title":"SEQUENTIAL PARS PLANA VITRECTOMY AND INVERTED INTERNAL LIMITING MEMBRANE FLAP TECHNIQUE FOR RHEGMATOGENOUS RETINAL DETACHMENTS WITH PERIPHERAL BREAKS AND CONCOMITANT NON-CAUSATIVE MACULAR HOLE IN NON-HIGHLY MYOPIC PATIENTS","authors":"G. Baltă, I. Tofolean, Tamara Tiu, Valentin Dinu, Cristina-Mihaela Alexandrescu, Florian N Baltă, Liliana-Mary Voinea","doi":"10.1097/iae.0000000000004180","DOIUrl":"https://doi.org/10.1097/iae.0000000000004180","url":null,"abstract":"\u0000 \u0000 To present the anatomical and functional results of sequential pars plana vitrectomy (PPV) for treating rhegmatogenous retinal detachment (RRD) with peripheral breaks and concomitant non-causative macular holes (MH) in non-highly myopic patients.\u0000 \u0000 \u0000 \u0000 Medical records of patients who underwent RRD surgical repair between 2017 and 2023 were reviewed. Of 980 patients with RRD, 10 had concurrent MH and underwent sequential PPV for RRD repair and air-endotamponade, followed by MH repair using the inverted internal limiting membrane (ILM) flap technique and C2F6-endoamponade after a minimum of 1 week. The main outcomes measured were best-corrected visual acuity (BCVA) change, retinal reattachment rate, MH closure rate, and closure type.\u0000 \u0000 \u0000 \u0000 The retinal reattachment rate was 90% after the primary surgery and 100% after subsequent surgery. MH closure was achieved in all cases. MH diameters ranged from 291 to 702 μm. Anatomical recovery showed mainly 1A closure types (90%). Functional recovery demonstrated significant BCVA improvement, with a mean visual acuity gain of 1.58 ± 0.41 logMAR.\u0000 \u0000 \u0000 \u0000 For this infrequent pathology, sequential surgery using the inverted ILM flap technique and air/gas-endotamponade yielded favorable anatomical and functional outcomes. This controlled and standardized approach using sequential surgeries contributes to the achievement of consistent results.\u0000","PeriodicalId":21178,"journal":{"name":"Retina","volume":"51 10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141353133","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
RetinaPub Date : 2024-06-12DOI: 10.1097/iae.0000000000004177
C. Fardeau, Gautier Breville, Arnaud-Louis Jeannerot, François Herrmann, Meriem Touati, Sophie Bonnin, T. Sales de Gauzy, Ayria Sadegh, Amira Toumi, Edoardo Baglivo, David Cohen, Marina Karmochkine, B. Bodaghi, Jörg D. Seebach, P. Le Hoang
{"title":"Cystoid Macular Edema in birdshot retinochoroïditis: long-term treatment study in 142 patients","authors":"C. Fardeau, Gautier Breville, Arnaud-Louis Jeannerot, François Herrmann, Meriem Touati, Sophie Bonnin, T. Sales de Gauzy, Ayria Sadegh, Amira Toumi, Edoardo Baglivo, David Cohen, Marina Karmochkine, B. Bodaghi, Jörg D. Seebach, P. Le Hoang","doi":"10.1097/iae.0000000000004177","DOIUrl":"https://doi.org/10.1097/iae.0000000000004177","url":null,"abstract":"\u0000 \u0000 To assess the long-term efficacy and safety of treatments for cystoid macular edema (CME) in birdshot retinochoroïditis (BRC)\u0000 \u0000 \u0000 \u0000 Observational retrospective study of 142 HLA-A29 positive patients with CME; the main outcome was the optical coherence tomography intra-retinal cysts change.\u0000 \u0000 \u0000 \u0000 During the mean follow up of 75 months [12-178], 61.3% patients were successfully treated using 1 to 3 treatment steps, the others needed more steps. At 6 months there were no significant effects on ME for anti-TNF (tumor necrosis factor) and IVIg (immunoglogulin) in contrast to antimetabolites (OR 1.98), systemic GCS (glucocorticosteroids), CsA (ciclosporineA) and TCZ (tocilizumab) (OR closed to 2.7), intraocular injected GCS (OR of 4.2) and IFN interferon (OR of 4.4). Compared to the 3 first steps of treatment, percentages of success trend to decline in the following steps, for systemic GCS (84% to 70%), anti-TNF (42% to 33%), and CsA (71% to 33%) while did not decrease for injected GCS (83% to 89%). ME recurrence occurred with the highest percentage for injected GCS (86.8%, p=0.01) and the lowest for TCZ (10.5%, p=0.001). IFN-α and TCZ were associated with the lowest prednisone daily dose.\u0000 \u0000 \u0000 \u0000 The classical uveitic CME therapeutic algorithm could be adapted to BRC.\u0000","PeriodicalId":21178,"journal":{"name":"Retina","volume":"49 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141354906","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
RetinaPub Date : 2024-06-11DOI: 10.1097/iae.0000000000004179
Stephanie Wangyu, Jennifer L. Jung, Paula E Pecen, Alan G. Palestine, Amit K. Reddy
{"title":"Intravitreal 0.18-mg fluocinolone acetonide implant for pediatric uveitis","authors":"Stephanie Wangyu, Jennifer L. Jung, Paula E Pecen, Alan G. Palestine, Amit K. Reddy","doi":"10.1097/iae.0000000000004179","DOIUrl":"https://doi.org/10.1097/iae.0000000000004179","url":null,"abstract":"\u0000 \u0000 We report the outcomes of the 0.18-mg intravitreal fluocinolone acetonide implant (FAi) in the treatment of pediatric non-infectious uveitis.\u0000 \u0000 \u0000 \u0000 A retrospective cohort study was performed on patients under 18 years of age who received FAi between June 1, 2020 and March 1, 2023. Data collected included demographics, uveitis diagnosis, use of anti-inflammatory therapy, visual acuity, intraocular pressure, and grading of uveitis activity. Uveitis recurrence was defined as increased inflammation that required additional anti-inflammatory therapy\u0000 \u0000 \u0000 \u0000 Eleven eyes from seven patients were included in this study. One patient (one eye) had a diagnosis of immune recovery uveitis and the remaining six patients (10 eyes) had pars planitis. The rate of remaining recurrence-free was 82% at 6 months, 60% at 12 months, and 60% at 24 months. Two of the six phakic eyes at baseline required cataract extraction during follow-up. Two of the four eyes that did not have IOP-lowering surgery prior to implantation required surgery in follow-up.\u0000 \u0000 \u0000 \u0000 The 0.18-mg FAi has a similar efficacy for the treatment of pediatric uveitis, particularly pars planitis, as in the adult population, although with higher rates of ocular hypertension requiring intervention.\u0000","PeriodicalId":21178,"journal":{"name":"Retina","volume":"22 21","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141357467","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}