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Reviews in obstetrics & gynecology最新文献

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Alcohol and breast cancer. 酒精和乳腺癌
Reviews in obstetrics & gynecology Pub Date : 2012-01-01
Athol Kent
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引用次数: 0
Hypertension control in pregnancy. 妊娠期高血压控制。
Reviews in obstetrics & gynecology Pub Date : 2012-01-01
Athol Kent
{"title":"Hypertension control in pregnancy.","authors":"Athol Kent","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":21170,"journal":{"name":"Reviews in obstetrics & gynecology","volume":"5 2","pages":"114"},"PeriodicalIF":0.0,"publicationDate":"2012-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3410513/pdf/RIOG005002_0114.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30813359","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Snippets. 片段。
Reviews in obstetrics & gynecology Pub Date : 2012-01-01
Athol Kent
{"title":"Snippets.","authors":"Athol Kent","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":21170,"journal":{"name":"Reviews in obstetrics & gynecology","volume":"5 3-4","pages":"e169-70"},"PeriodicalIF":0.0,"publicationDate":"2012-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3594865/pdf/RIOG005003_e169a.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31302453","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
New Success With Microbicides and Pre-Exposure Prophylaxis for Human Immunodeficiency Virus (HIV): Is Female-Controlled Prevention the Answer to the HIV Epidemic? 杀菌剂和暴露前预防人类免疫缺陷病毒(HIV)的新成功:女性控制的预防是HIV流行的答案吗?
Reviews in obstetrics & gynecology Pub Date : 2012-01-01
Jessica Opoku-Anane, Khady Diouf, Nawal M Nour
{"title":"New Success With Microbicides and Pre-Exposure Prophylaxis for Human Immunodeficiency Virus (HIV): Is Female-Controlled Prevention the Answer to the HIV Epidemic?","authors":"Jessica Opoku-Anane,&nbsp;Khady Diouf,&nbsp;Nawal M Nour","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Women who cannot negotiate condom use with their partners, often due to socioeconomic factors and sexual abuse, have no means of preventing themselves from acquiring the human immunodeficiency virus (HIV). There is a need to develop HIV-preventive methods initiated and controlled by women. Microbicides and other pre-exposure prophylaxis may help fill that need. Although two decades of research on broad-spectrum microbicides have generally been disappointing, recent trials with HIV-specific agents have yielded promising initial results. A new era of clinical research involves novel biochemical prevention methods, including HIV-specific vaginal microbicides and oral antiretroviral chemoprophylaxis drugs (pre-exposure prophylaxis; PrEP) that may help provide more control for women.</p>","PeriodicalId":21170,"journal":{"name":"Reviews in obstetrics & gynecology","volume":"5 1","pages":"50-5"},"PeriodicalIF":0.0,"publicationDate":"2012-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3349924/pdf/RIOG005001_0050.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30614431","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Antihypertensives in pregnancy. 妊娠期抗高血压药物。
Reviews in obstetrics & gynecology Pub Date : 2012-01-01
Athol Kent
{"title":"Antihypertensives in pregnancy.","authors":"Athol Kent","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":21170,"journal":{"name":"Reviews in obstetrics & gynecology","volume":"5 1","pages":"57-8"},"PeriodicalIF":0.0,"publicationDate":"2012-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3349931/pdf/RIOG005001_057a.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30614434","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Premature delivery and the millennium development goal. 早产与千年发展目标。
Reviews in obstetrics & gynecology Pub Date : 2012-01-01
Nawal M Nour
{"title":"Premature delivery and the millennium development goal.","authors":"Nawal M Nour","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Worldwide, approximately 15 million babies (1 in 10) are born prematurely each year. Prematurity is the leading cause of death among newborns, accounting for 1 million deaths per year, and, after pneumonia, is the second leading cause of death in children under age 5 years. Newborns who do survive preterm delivery (PTD) struggle with visual, auditory, and learning disabilities. In order to reach the fourth Millennium Development Goal (MDG-4) of reducing the mortality rate in children under age 5 years by two-thirds between 1990 and 2015, there must be significantly fewer PTDs. In high-income nations, 50% of babies born at 24 weeks survive, whereas in low-resource nations, this survival rate is not achieved until 32 weeks of gestation. Over 90% of babies born in low-resource settings before 28 weeks die in the first few days of life (< 10% die in high-income nations), a 10:90 survival gap. Over 60% of PTDs worldwide occur in Sub-Saharan Africa and South Asia. Risk factors for PTD include adolescent pregnancy, short interval between births, poor prepregnancy weight (very low or high body mass index), chronic diseases (diabetes and hypertension), infectious disease, substance abuse, cervical incompetence, and poor psychological health. Thus, a commitment to improving maternal health and the quality of prenatal care is necessary to achieve the MDG-4.</p>","PeriodicalId":21170,"journal":{"name":"Reviews in obstetrics & gynecology","volume":"5 2","pages":"100-5"},"PeriodicalIF":0.0,"publicationDate":"2012-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3410509/pdf/RIOG005002_0100.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30813354","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Selective serotonin reuptake inhibitors and neonatal anomalies. 选择性血清素再摄取抑制剂与新生儿异常。
Reviews in obstetrics & gynecology Pub Date : 2012-01-01
Athol Kent
{"title":"Selective serotonin reuptake inhibitors and neonatal anomalies.","authors":"Athol Kent","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":21170,"journal":{"name":"Reviews in obstetrics & gynecology","volume":"5 2","pages":"113"},"PeriodicalIF":0.0,"publicationDate":"2012-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3410512/pdf/RIOG005002_0113.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30813357","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Congenital cystic lesions of the lung: congenital cystic adenomatoid malformation and bronchopulmonary sequestration. 先天性肺囊性病变:先天性囊性腺瘤样畸形和支气管肺隔离。
Reviews in obstetrics & gynecology Pub Date : 2012-01-01
Anna K Sfakianaki, Joshua A Copel
{"title":"Congenital cystic lesions of the lung: congenital cystic adenomatoid malformation and bronchopulmonary sequestration.","authors":"Anna K Sfakianaki,&nbsp;Joshua A Copel","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Congenital cystic lesions of the lung in fetuses are rare. The most common malformations of the lower respiratory tract are congenital cystic adenomatoid malformation and bronchopulmonary sequestration. With the increased use of obstetric ultrasound, cystic lung lesions are detected more often antenatally, which allows for proper planning of peripartum and neonatal management. This article discusses a range of diagnostic and management options.</p>","PeriodicalId":21170,"journal":{"name":"Reviews in obstetrics & gynecology","volume":"5 2","pages":"85-93"},"PeriodicalIF":0.0,"publicationDate":"2012-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3410507/pdf/RIOG005002_0085.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30813471","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Electronic Fetal Monitoring: A Defense Lawyer's View. 电子胎儿监护:辩护律师的观点。
Reviews in obstetrics & gynecology Pub Date : 2012-01-01
Thomas P Sartwelle
{"title":"Electronic Fetal Monitoring: A Defense Lawyer's View.","authors":"Thomas P Sartwelle","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Electronic fetal monitoring (EFM) has been used for four decades, after its introduction without clinical trials. EFM spawned a birth injury litigation crisis centered on the myth that it predicts cerebral palsy (CP). The myth has resulted in lottery-like judgments against physicians. The American Congress of Obstetricians and Gynecologists (ACOG) and sister organizations worldwide have the power to halt EFM's clinical proliferation and the undeserved litigation verdicts against physicians unjustly blamed for causing CP. This power has been unused. If ACOG and other organizations would declare EFM unreliable, it could change the clinical standard of care and alleviate the CP-EFM malpractice lottery.</p>","PeriodicalId":21170,"journal":{"name":"Reviews in obstetrics & gynecology","volume":"5 3-4","pages":"e121-5"},"PeriodicalIF":0.0,"publicationDate":"2012-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3594858/pdf/RIOG005003_e121.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31300885","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Bevacizumab-mediated interference with VEGF signaling is sufficient to induce a preeclampsia-like syndrome in nonpregnant women. 贝伐单抗介导的VEGF信号干扰足以在非孕妇中诱发子痫前期样综合征。
Reviews in obstetrics & gynecology Pub Date : 2012-01-01
Sarah N Cross, Elena Ratner, Thomas J Rutherford, Peter E Schwartz, Errol R Norwitz
{"title":"Bevacizumab-mediated interference with VEGF signaling is sufficient to induce a preeclampsia-like syndrome in nonpregnant women.","authors":"Sarah N Cross,&nbsp;Elena Ratner,&nbsp;Thomas J Rutherford,&nbsp;Peter E Schwartz,&nbsp;Errol R Norwitz","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Preeclampsia (gestational proteinuric hypertension) complicates 5% to 8% of all pregnancies, and is a major cause of maternal and perinatal morbidity and mortality. It is a multisystem disorder specific to human pregnancy and the puerperium. Although the etiology is unknown, increasing evidence from both animal and human studies suggests that an imbalance in circulating pro-(vascular endothelial growth factor [VEGF], placental growth factor) and anti-angiogenic factors (soluble fms-like tyrosine kinase 1, soluble endoglin) may be important. Bevacizumab (Avastin®; Genentech, South San Francisco, CA), a humanized recombinant monoclonal IgG antibody that binds VEGF, has been shown to inhibit endothelial cell proliferation, suppress angiogenesis, and shrink a variety of solid tumors. We present two cases of bevacizumab toxicity that mimic preeclampsia with a reversible syndrome characterized by acute-onset severe hypertension, proteinuria, central nervous system irritability (headache, photophobia, blurred vision, seizures), abnormal laboratory tests (elevated liver function tests, thrombocytopenia), and evidence of reversible posterior leukoencephalopathy on neuroimaging. In both cases, the clinical and laboratory manifestations returned to normal with discontinuation of bevacizumab therapy and supportive care. Bevacizumab toxicity can mimic preeclampsia in nonpregnant women. These data suggest that interference with VEGF signaling is sufficient to induce a preeclampsia-like syndrome in nonpregnant patients. VEGF signaling therefore appears to play a central role-perhaps the central role-in the pathogenesis of preeclampsia, and provides a potential biomarker for the prediction, prevention, and treatment of this dangerous disorder.</p>","PeriodicalId":21170,"journal":{"name":"Reviews in obstetrics & gynecology","volume":"5 1","pages":"2-8"},"PeriodicalIF":0.0,"publicationDate":"2012-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3349918/pdf/RIOG005001_0002.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30614425","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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