{"title":"Dietary intake of dioxins and cancer - where do we stand?","authors":"Andrea Kaifie, Thomas Göen","doi":"10.1515/reveh-2025-0024","DOIUrl":"https://doi.org/10.1515/reveh-2025-0024","url":null,"abstract":"<p><p>In highly dioxin exposed populations, an elevated cancer risk and cancer mortality has been described. Environmental background exposure and cancer risk has not been analyzed systematically, so far. We conducted a structured review in order to identify relevant studies. Using the PECO scheme we included altogether 13 studies from initially 4,983 articles. Epidemiological data from the included studies did not indicate an increased risk of cancer or increased cancer mortality for all cancer, breast cancer, and sarcoma caused by dietary intake of dioxins. For Non-Hodgkin`s lymphoma, the study situation was in parts inconsistent showing for example an increased risk for DL-PCBs in one study and for furans in another study. Several studies evaluating the effect of dietary dioxin exposure and elevated cancer risk or cancer mortality did not observe a clear association. For Non-Hodgkin`s lymphoma further investigations are needed due to inconsistent results among the studies.</p>","PeriodicalId":21165,"journal":{"name":"Reviews on Environmental Health","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144151336","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Connecting the dots: environmental pollution and Autism Spectrum Disorder.","authors":"Bidisha Bhattacharya, Devinder Toor, Mallika Chatterjee","doi":"10.1515/reveh-2024-0123","DOIUrl":"https://doi.org/10.1515/reveh-2024-0123","url":null,"abstract":"<p><p>Autism Spectrum Disorder (ASD) is a complex neurodevelopmental condition characterized by challenges in social communication and repetitive behavior. While the exact etiology of ASD remains elusive, researchers have increasingly turned their attention to the role of environmental factors in its development. Among these factors, environmental pollution has emerged as a potential contributor to the rising prevalence of ASD cases worldwide. This review delves into the growing body of scientific evidence suggesting a significant association between environmental pollution and the risk of ASD. It explores the environmental pollution that have been implicated, including air pollution, water contaminants, heavy metals, pesticides, and endocrine-disrupting chemicals. The detrimental impact of these pollutants on the developing brain, particularly during critical periods of gestation and early childhood has been discussed. This will provide insights into the possible mechanisms by which the various pollutants may influence the neurodevelopmental pathways underlying ASD. Additionally, the potential interplay between genetic susceptibility and environmental exposure is explored to better understand the multifactorial nature of ASD causation. Considering the alarming increase in ASD prevalence and the ubiquity of environmental pollutants, this review emphasizes the urgent need for further investigation and the adoption of comprehensive preventive measures.</p>","PeriodicalId":21165,"journal":{"name":"Reviews on Environmental Health","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144044576","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Fine particulate matter exposure and cancer risk: a systematic review and meta-analysis of prospective cohort studies.","authors":"Yuting Feng, Jiaoyuan Li, Yi Wang, Tongxin Yin, Qiankun Wang, Liming Cheng","doi":"10.1515/reveh-2024-0171","DOIUrl":"https://doi.org/10.1515/reveh-2024-0171","url":null,"abstract":"<p><p>Studies examining the relationship between fine particulate matter (PM<sub>2.5</sub>) exposure and cancer risk is inconclusive, with an evident scarcity of comprehensive data on the overall cancer risk. Given the emergence of new evidence, updated meta-analyses is essential. A search was performed on multiple databases including PubMed, Embase, Scopus, Web of Science, and the Cochrane Library up to Jan 2025. Hazard ratios (HRs), relative risks (RRs), or incidence rate ratios (IRRs) with their 95 % confidence intervals (CIs) were extracted and pooled. Moreover, a comprehensive and detailed quality assessment of the included studies was conducted to validate the plausibility of the findings. Overall, 57 original studies were included, covering 36 cancer categories and including overall cancer and malignancies specific to particular anatomical sites. For each increase of 10 μg per cubic meter in PM<sub>2.5</sub> concentration, there was an observed pooled HR of 1.07 for overall cancer (95 %CI:1.02-1.13). In the case of site-specific cancers, the pooled HRs were 1.11 (95 %CI:1.07-1.15), 1.06 (95 %CI:1.02-1.11), 1.17 (95 %CI:1.07-1.28), and 1.14 (95 %CI:1.03-1.26) for lung, breast, liver and esophageal cancers, respectively. Furthermore, PM<sub>2.5</sub> exposure may potentially correlate with the risk of cancers at other anatomical locations including upper aerodigestive tract, oral cavity, kidney, skin, as well as digestive organs. In light of available evidence, it is inferred that PM<sub>2.5</sub> exposure could potentially raise overall cancer risk with moderate certainty. As for site-specific malignancies, there is very low certainty evidence for lung cancer, low certainty evidence for breast cancer, and moderate certainty evidence for both liver and esophageal cancers.</p>","PeriodicalId":21165,"journal":{"name":"Reviews on Environmental Health","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144021502","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Sustainable materials and energy from pine needle waste - a review.","authors":"Niteen R Yeole","doi":"10.1515/reveh-2024-0146","DOIUrl":"https://doi.org/10.1515/reveh-2024-0146","url":null,"abstract":"<p><p>The accumulation of pine needle waste on the floor of a large pine forest is a severe problem. Dry pine needle waste acts as a fuel for forest fires which release harmful compounds into the atmosphere. The particulate matter in the smoke, released during forest fires, adversely affects human health. The top layer of fertile ground is harmed by unburned bioresidue. Moreover, pine needles provide the ground for pests' growth, creating a threat to nearby vegetation and structures. Managing pine needle waste through conversion into sustainable materials and energy will help reduce environmental pollution and health risks. The biosorbents from pine needle waste can be used to remove heavy metals and dyes from wastewater. The remote forest areas may be supplied with electricity obtained through the gasification of pine needles. The extracts from pine needles offer a variety of benefits such as anti-inflammatory, antioxidant, and antimicrobial. Currently, laws and subsidies promote the use of forest biomass to create biofuels. The present paper reviews the literature, provides the status and prospects, and analyses the literature data on the synthesis of bio briquettes, using the analysis of variance tool of Microsoft Excel<sup>®</sup>.</p>","PeriodicalId":21165,"journal":{"name":"Reviews on Environmental Health","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144027241","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nadya Diena Rahmah, Adriyan Pramono, Muflihatul Muniroh
{"title":"Interrelation between prenatal mercury-selenium exposure and glutathione gene polymorphism: impact on growth and development in children.","authors":"Nadya Diena Rahmah, Adriyan Pramono, Muflihatul Muniroh","doi":"10.1515/reveh-2024-0169","DOIUrl":"https://doi.org/10.1515/reveh-2024-0169","url":null,"abstract":"<p><p>Prenatal exposure to mercury (Hg) and selenium (Se) has significant implications for children growth and development, especially in populations with high seafood consumption. Organic mercury (methylmercury) is particularly hazardous to neurodevelopment, while selenium serves as a critical micronutrient with antioxidant properties that might protect against mercury-related disruptions. Genetic variations in glutathione-related genes, such as those encoding glutathione peroxidase (GPX) and glutathione S-transferase (GST), influence the body's ability to metabolize mercury and utilize selenium. These polymorphisms can modulate mercury detoxification and selenium bioavailability, impacting mercury bioaccumulation and the oxidative balance essential for fetal growth and development. This narrative review explores the complex interactions between prenatal mercury and selenium exposure and glutathione gene polymorphisms, elaborating on their effects on children's growth and developmental outcomes.</p>","PeriodicalId":21165,"journal":{"name":"Reviews on Environmental Health","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143753848","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Qiling Zhu, Shiwei Jin, Daniel D Gang, Fangxing Yang
{"title":"A review in analytical progress for house dust mite allergens.","authors":"Qiling Zhu, Shiwei Jin, Daniel D Gang, Fangxing Yang","doi":"10.1515/reveh-2024-0177","DOIUrl":"https://doi.org/10.1515/reveh-2024-0177","url":null,"abstract":"<p><p>House dust mite (HDM) allergens are one of the most important causes of allergenic diseases in the indoor environment. The World Health Organization (WHO) has defined risk thresholds for Group I HDM allergens as a concentration of 2 and 10 μg/mL in dust for producing asthma risk and polar asthma attacks, respectively. Continuing exposure to high concentrations of HDM allergens greatly increases the risk of developing allergic diseases. Therefore, it's necessary to determine the exposure levels of HDM allergens to estimate the risk. So, various approaches have been developed to directly or indirectly detect HDM allergens in the environment. This paper overviews the developmental progress of HDM allergen detection and introduces the principle of HDM allergen detection methods, including semi-quantitative radioallergosorbent test (RAST), ACAREX test, dot immunobinding assay (DIBA), radioimmunoassay (RIA) which combines the high sensitivity and accuracy, enzyme-linked immunosorbent assay (ELISA) with high accuracy, fluorescent multiple arrays which can simultaneously detect multiple HDM allergens, polymerase chain reaction (PCR), and liquid chromatograph-mass spectrometer (LC-MS) with high sensitivity and accuracy. The paper provides an overall understanding of the development of HDM allergen detection methods and guidance for choosing an appropriate method to detect HDM allergens.</p>","PeriodicalId":21165,"journal":{"name":"Reviews on Environmental Health","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143617048","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Fatima A Mazahir, Ankita Shukla, Najwa A Albastaki
{"title":"The association of particulate matter PM<sub>2.5</sub> and nitrogen oxides from ambient air pollution and mental health of children and young adults- a systematic review.","authors":"Fatima A Mazahir, Ankita Shukla, Najwa A Albastaki","doi":"10.1515/reveh-2024-0120","DOIUrl":"https://doi.org/10.1515/reveh-2024-0120","url":null,"abstract":"<p><strong>Introduction: </strong>The developing brain, especially vulnerable during neuroplastic phases, is influenced by environmental and genetic factors. Understanding the impacts of air pollution on children's and young adults' mental health is an emerging research field.</p><p><strong>Content: </strong>This review systematically examines the adverse associations of ambient air pollutants on mental health. A database search using Scopus, EMBASE, Global Health, and PsycINFO included articles from 2013 onwards, following PRISMA guidelines. Of the 787 identified articles, 62 met the inclusion criteria. Quality was assessed using the EPHPP tool, and Best Evidence Synthesis (BES) evaluated the findings.</p><p><strong>Summary: </strong>The review found 36 associations between ambient air pollutants and adverse mental health outcomes across seven life-course exposure periods. Strong evidence linked early-life PM<sub>2.5</sub> and NO<sub>2</sub> exposures to Autism Spectrum Disorder (ASD) and childhood exposures to Attention Deficit Hyperactivity Disorder (ADHD). Significant, though inconsistent, associations were found between air pollutants and cognitive impairments, anxiety, depression, self-harm, and other behavioral problems. The heterogeneity of exposure limits and lack of experimental studies hinder causal assessment.</p><p><strong>Outlook: </strong>Compelling evidence links early-life and childhood exposure to PM<sub>2.5</sub> and NO<sub>2</sub> with ASD and ADHD. These findings highlight the need for public health policy changes and further research to explore these associations comprehensively.</p>","PeriodicalId":21165,"journal":{"name":"Reviews on Environmental Health","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143617051","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Exposure to air pollution from coal-fired power plants and impacts on human health: a scoping review.","authors":"Nomfundo Mahlangeni, Thandi Kapwata, Candice Webster, Chantelle Howlett-Downing, Caradee Y Wright","doi":"10.1515/reveh-2024-0173","DOIUrl":"https://doi.org/10.1515/reveh-2024-0173","url":null,"abstract":"<p><p>Communities living in proximity to coal-fired power plants (CFPPs) may be at greater risk of negative health impacts from exposure to air pollution than communities living further away. The aim of this scoping review was to provide an update on the evidence of the health risks of air pollution exposure associated with living in proximity to CFPPs and to evaluate the relationship between residential proximity and the extent of the health burden. We followed the PRISMA-ScR guidelines and searched Google Scholar, PubMed, ScienceDirect, Scopus and Web of Science for relevant studies from inception up to 31 January 2024. Fifty-six studies were included with most articles published from 2016 to 2023 (n=33, 59 %) and 35 were in high income countries (63 %). Living close to CFPPs was frequently associated with increased odds or likelihood of respiratory disorders, adverse birth outcomes and child developmental issues. Interventions such as emission control systems or total shutdown of CFPPs led to improved health among communities living near CFPPs. The review highlights the health impacts from air pollution associated with living in proximity to CFPPs and the need for policy measures to reduce air pollution by installing emission control technologies or transitioning to cleaner energy sources.</p>","PeriodicalId":21165,"journal":{"name":"Reviews on Environmental Health","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143557818","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Plant endophytic bacteria reduce phthalates accumulation in soil-crop-body system: a review.","authors":"Ziyi Huang, Yanli Chen, Jieying Zou, Peng Zhou, Xingyu Huang, Ruihao Zhuang, Xinyu Wang, Lihui Liu","doi":"10.1515/reveh-2024-0040","DOIUrl":"https://doi.org/10.1515/reveh-2024-0040","url":null,"abstract":"<p><p>Phthalate esters (PAEs) represent a class of widely utilized plasticizers, resulting in their pervasive presence in soil and agricultural crops, which poses significant risks to human health. This review examines the current state of PAE pollution, the microbial resources available for PAE degradation, and the associated degradation pathways. It highlights the advantages of endophytic bacteria over environmental microorganisms, including the prolonged survival of inoculated strains, <i>in vivo</i> biodegradation of PAEs, and multifunctional capabilities. Furthermore, the mechanisms by which endophytic bacteria mitigate PAE accumulation across the three defense lines (soil, crops, and the human body) are elucidated. The integrated approach of employing both plants and microbial agents for the remediation of PAEs demonstrates considerable potential for ensuring the safety of agricultural products and safeguarding human health. This work offers new insights into addressing the challenges posed by organic pollutant contamination and reducing PAE accumulation in the human body.</p>","PeriodicalId":21165,"journal":{"name":"Reviews on Environmental Health","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143123507","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"School built environment and children's health: a scientometric analysis.","authors":"Mingxin Zhang, Xue Meng","doi":"10.1515/reveh-2024-0137","DOIUrl":"https://doi.org/10.1515/reveh-2024-0137","url":null,"abstract":"<p><p>The school built environment is closely related to children's health, and research on this topic is increasing. However, bibliometric analyses seeking to provide a comprehensive understanding of the research landscape and key themes in the field are lacking. This study comprehensively explored the global trends and research hotspots on the associations between school built environment and children's health. We used a scientometric analysis to review the research progress. The temporal distribution of publications, scientific collaborations, research hotspots, research frontiers, and co-citations over the past 30 years were analyzed. The results show that the number of publications in this field rose significantly between 1987 and 2025, with research hotspots focusing on physical activity, performance, behavior, perception, thermal comfort, and indoor air quality. Environmental themes related to children's health fall into four main groups: the built environment related to children's activities, intelligent learning environments, indoor environments and interiors, and natural environments. Health outcomes and measures that reflect physiological, psychological, cognitive, behavioral, and physical factors are discussed. This study provides a broad understanding of research issues and trends related to the school built environment and children's health.</p>","PeriodicalId":21165,"journal":{"name":"Reviews on Environmental Health","volume":" ","pages":""},"PeriodicalIF":3.0,"publicationDate":"2025-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143024463","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}