Reviews on Environmental Health最新文献

A systematic review of radon concentrations and its lung cancer burden in Iran over two decades (2024-2000). 二十年来伊朗氡浓度及其肺癌负担的系统回顾（2024-2000）。

IF 4.5 4区医学

Reviews on Environmental Health Pub Date : 2026-05-06 DOI: 10.1515/reveh-2025-0146

Niloufar Borhani Yazdi, Mohammad Khanizadeh, Mansour Shamsipour, Sasan Faridi, Kazem Naddafi, Fatemeh Momeniha, Mohammad Sadegh Hassanvand

{"title":"A systematic review of radon concentrations and its lung cancer burden in Iran over two decades (2024-2000).","authors":"Niloufar Borhani Yazdi, Mohammad Khanizadeh, Mansour Shamsipour, Sasan Faridi, Kazem Naddafi, Fatemeh Momeniha, Mohammad Sadegh Hassanvand","doi":"10.1515/reveh-2025-0146","DOIUrl":"https://doi.org/10.1515/reveh-2025-0146","url":null,"abstract":"The second most common cause of lung cancer after smoking is radon which is a naturally occurring radioactive gas. Although the levels of radon have been recorded in some parts of Iran, the general health effect of radon remains unclear. A systematic review that was conducted in this study determined the level of indoor radon in Iranian provinces and approximated the burden of lung cancer as a result of this exposure using an accepted risk assessment model. An extensive search in both national and international databases revealed that 263 records were found, 45 of which were included in the study based on the PRISMA guidelines. The data were taken out of 60 cities in 18 provinces organized into nine geographic zones. Systematic evaluation was done on key modifying factors which included season, building materials, floor level, ventilation, and building age. Data on radon exposure were augmented with provincial lung cancer disability-adjusted life years (DALYs) of the Global Burden of Disease (GBD) study. The uncertainty in exposure and the exposure-response coefficient was also taken into consideration using Monte Carlo simulations. The radon-attributable lung cancer morbidity was estimated to be approximately 19,400 DALYs/year, which was equivalent to the population attributable fraction (PAF) of 10.6 (95 % CI: 8.1-13.3 %). The provincial PAFs were between 0.9 % and 44.3 % with the greatest burden observed in Tehran, Mazandaran and Khorasan-e-Razavi. In some regions, radon was responsible for more than 25 % (95 % CI: 20.1-31.2 %) of the lung cancer burden. These findings point to the existence of serious regional differences and the necessity of the immediate attention to radon monitoring, mitigation, and Governmental policies to prevent cancers and improve the safety of buildings in Iran.","PeriodicalId":21165,"journal":{"name":"Reviews on Environmental Health","volume":" ","pages":""},"PeriodicalIF":4.5,"publicationDate":"2026-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147842259","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Revisiting the impacts of geographical aspects on public health in the tropical-Asian countries: a review. 重新审视地理因素对热带亚洲国家公共卫生的影响：综述。

IF 4.5 4区医学

Reviews on Environmental Health Pub Date : 2026-04-24 DOI: 10.1515/reveh-2025-0111

Arif Ashari, Muhamad Ervin, Grace Helena Amaranthois Kapisan, Muhammad Asrori Indra Wardoyo, Raisya Arzety Olivia, Bagus Tegar Sakti Prakosa

{"title":"Revisiting the impacts of geographical aspects on public health in the tropical-Asian countries: a review.","authors":"Arif Ashari, Muhamad Ervin, Grace Helena Amaranthois Kapisan, Muhammad Asrori Indra Wardoyo, Raisya Arzety Olivia, Bagus Tegar Sakti Prakosa","doi":"10.1515/reveh-2025-0111","DOIUrl":"https://doi.org/10.1515/reveh-2025-0111","url":null,"abstract":"Public health in an area is influenced by various factors. One of these factors is the environment, which is related to geographical aspects such as climate and topography. This paper evaluates the impact of geographical aspects on public health in tropical Asian countries. This paper is a systematic literature review organized using the PRISMA approach. Search keywords were determined using the PCC method. Documents reviewed in this study were obtained from the Scopus database. There were 1734 documents collected. Of these, 191 were selected through the extraction process and continued in the review. The results of this study show that research in this field has been conducted for 150 years. However, many studies have only been produced in the last two decades. This review provides evidence that geographical aspects affect public health in tropical Asian countries. The climate is an important and widely discussed geographical aspect. Climate-related variables appeared in 84 % of studies, whereas topography and environment appeared in less than 7 %. The remaining articles discuss the application of geography in disease studies and the combination of several variables. This study synthesizes 150 years of evidence to establish a regional theory of geographical aspects-health interactions. Climate is the geographical aspect that has the most influence on disease and public health. This information is essential to strengthen the foundation of medical geography and health geography, especially in Southeast Asia.","PeriodicalId":21165,"journal":{"name":"Reviews on Environmental Health","volume":" ","pages":""},"PeriodicalIF":4.5,"publicationDate":"2026-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147779824","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The impact of micro- and nanoplastics on human pulmonary health; an umbrella review. 微塑料和纳米塑料对人体肺部健康的影响；总结性评论。

IF 4.5 4区医学

Reviews on Environmental Health Pub Date : 2026-04-16 DOI: 10.1515/reveh-2025-0159

Hooshyar Hossini, Roya Vesal Azad, Sina Saryazdi, Melika Taherifar, Mahdi Farzadkia

{"title":"The impact of micro- and nanoplastics on human pulmonary health; an umbrella review.","authors":"Hooshyar Hossini, Roya Vesal Azad, Sina Saryazdi, Melika Taherifar, Mahdi Farzadkia","doi":"10.1515/reveh-2025-0159","DOIUrl":"https://doi.org/10.1515/reveh-2025-0159","url":null,"abstract":"The pervasive environmental contamination of microplastics (MPs) and nanoplastics (NPs) has raised significant public health concerns, with the respiratory tract being a critical route of exposure. While a growing body of evidence suggests adverse pulmonary effects, a comprehensive synthesis of systematic reviews (SRs) is lacking. This umbrella review systematically consolidates evidence from published SRs to evaluate the impact of MP and NP exposure on human pulmonary health. Accordingly, a comprehensive literature search was conducted across multiple databases. Fifteen SRs meeting the inclusion criteria were critically appraised using the AMSTAR-2 tool and included for narrative synthesis. The evidence unequivocally links MP/NP exposure to a spectrum of respiratory pathologies. Key determinants of toxicity can include particle size, shape, and polymer chemistry. NPs penetrate deeply into alveoli, causing oxidative stress, inflammation, and translocation, while MPs act as persistent irritants in the airways. Exposure is associated with acute conditions (airway inflammation, alveolar damage) and chronic diseases, including chronic bronchitis, chronic obstructive pulmonary disease (COPD) exacerbation, and pulmonary fibrosis. These effects lead to functional impairments such as reduced gas exchange and a progressive decline in lung function. Urban residents, occupational workers, and children are identified as high-risk populations due to heightened exposure and susceptibility. This synthesis study establishes MPs and NPs as a significant and multifaceted hazard to respiratory health. Addressing the global plastic pollution crisis at its source is paramount for protecting respiratory health.","PeriodicalId":21165,"journal":{"name":"Reviews on Environmental Health","volume":" ","pages":""},"PeriodicalIF":4.5,"publicationDate":"2026-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147717654","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Letters provide a forum for public engagement with geoengineering. 信件为公众参与地球工程提供了一个论坛。

IF 4.5 4区医学

Reviews on Environmental Health Pub Date : 2026-04-13 DOI: 10.1515/reveh-2025-0161

Timothy Daly, Jaime A Teixeira da Silva, Serhii Nazarovets

引用次数: 0

Lead and cancer: a narrative review and risk of bias assessment (2003-2020). 铅与癌症：一项叙事回顾和偏见风险评估（2003-2020）。

IF 4.5 4区医学

Reviews on Environmental Health Pub Date : 2026-04-13 DOI: 10.1515/reveh-2025-0120

Carol Cusack, Tara C Serio, Noelle B Henderson, Kathryn B Egan, Zheng Li, Teresa W Wang

{"title":"Lead and cancer: a narrative review and risk of bias assessment (2003-2020).","authors":"Carol Cusack, Tara C Serio, Noelle B Henderson, Kathryn B Egan, Zheng Li, Teresa W Wang","doi":"10.1515/reveh-2025-0120","DOIUrl":"10.1515/reveh-2025-0120","url":null,"abstract":"Lead exposure may contribute to harmful human health effects, but evidence of its carcinogenicity is limited. The International Agency for Research on Cancer (IARC) in 2006 classified lead as \"probably carcinogenic\" (Group 2A), based on limited evidence in humans and sufficient evidence in animals. To further synthesize evidence on lead's carcinogenicity, this review included a literature search and risk of bias assessment of 43 peer-reviewed epidemiological studies on lead exposure and cancer outcomes published between 2003 and 2020. Using the National Toxicology Program's Office of Health Assessment and Translation Risk of Bias approach, 13 Tier One studies (primarily low risk) and 30 Tier Two studies (low and high risk) were identified. These studies characterized lead exposure through biologic media (i.e., blood, urine, tissues, hair, nails), and/or work histories, and evaluated cancers of the biliary tract, brain and central nervous system, breast, digestive tract, head and neck, blood, mesothelium, reproductive organs, respiratory tract, skin, thyroid, and urinary tract. Notably, breast, thyroid, and head and neck cancers were not previously included in the IARC 2006 monograph. Across all site-specific cancers examined, at least one study reported an association with lead exposure except for skin cancer. Respiratory tract cancers had the most epidemiologic studies showing positive associations with lead exposure. Study limitations were commonly tied to risk of bias for confounding, exposure characterization, and outcome assessments. Taken together, future studies would benefit from robust experimental designs with thorough adjustments for confounders, large diverse populations, and standardized exposure assessments particularly for cancers with limited data.","PeriodicalId":21165,"journal":{"name":"Reviews on Environmental Health","volume":" ","pages":""},"PeriodicalIF":4.5,"publicationDate":"2026-04-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13130192/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147663087","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Monoclonal gammopathy of undetermined significance in individuals exposed to pesticides: systematic review and meta-analysis. 暴露于农药个体的单克隆γ病的不确定意义：系统评价和荟萃分析。

IF 4.5 4区医学

Reviews on Environmental Health Pub Date : 2026-04-08 DOI: 10.1515/reveh-2025-0022

Ana Flávia Redolfi Oliota, Mariana Millan Fachi, Ademar Dantas da Cunha Junior, Maria Lucia Frizon Rizzotto

{"title":"Monoclonal gammopathy of undetermined significance in individuals exposed to pesticides: systematic review and meta-analysis.","authors":"Ana Flávia Redolfi Oliota, Mariana Millan Fachi, Ademar Dantas da Cunha Junior, Maria Lucia Frizon Rizzotto","doi":"10.1515/reveh-2025-0022","DOIUrl":"10.1515/reveh-2025-0022","url":null,"abstract":"Monoclonal gammopathy of undetermined significance (MGUS) is an asymptomatic blood disorder that precedes multiple myeloma, and its etiology remains incompletely understood. Risk factors described in the literature include advanced age, male sex, Black race, a family history of plasma cell disorders, and the presence of chronic inflammatory or autoimmune conditions. Furthermore, direct exposure to pesticides has been proposed as a potentially modifiable risk factor. Accordingly, this study aimed to synthesize and evaluate the available evidence on MGUS prevalence and its possible relationship with occupational pesticide exposure among rural workers and pesticide applicators, including prevalence data when reported. A systematic review with meta-analysis was conducted according to Cochrane recommendations. Literature searches were conducted in October 2024 using the Medline (PubMed), Scopus, and Cochrane Library databases to identify relevant primary studies. Four eligible observational studies evaluating MGUS in participants directly exposed to pesticides were included. The studies reported positive associations between specific pesticides, such as aldrin, dieldrin, a carbon tetrachloride/carbon disulfide mixture, chlorothalonil, petroleum-derived products, and permethrin, and the occurrence of MGUS among rural workers. These findings were analyzed qualitatively due to methodological heterogeneity that precluded pooling of risk estimates. The meta-analysis, restricted to prevalence outcomes, showed that MGUS prevalence increases with age, suggesting age as an important risk factor. The scarcity of published studies and methodological heterogeneity highlight the need for further investigations to better characterize environmental and occupational risks associated with MGUS, which may inform future preventive strategies in higher-risk populations.","PeriodicalId":21165,"journal":{"name":"Reviews on Environmental Health","volume":" ","pages":""},"PeriodicalIF":4.5,"publicationDate":"2026-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147646098","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Narrative review of the multisystem health impacts of air pollution in East Asia: epidemiological evidence and policy implications. 东亚空气污染多系统健康影响的叙述性审查：流行病学证据和政策影响。

IF 4.5 4区医学

Reviews on Environmental Health Pub Date : 2026-03-04 DOI: 10.1515/reveh-2025-0123

Shi Liang, Qian Liang, Ning Liang

引用次数: 0

Can cadmium toxicity be a driving force for iron deficiency anemia - a systematic review and meta-analysis. 镉毒性是否可能是缺铁性贫血的驱动力——一项系统综述和荟萃分析。

IF 4.5 4区医学

Reviews on Environmental Health Pub Date : 2026-02-20 DOI: 10.1515/reveh-2025-0080

Irem Akin, Nuray Yazihan

{"title":"Can cadmium toxicity be a driving force for iron deficiency anemia - a systematic review and meta-analysis.","authors":"Irem Akin, Nuray Yazihan","doi":"10.1515/reveh-2025-0080","DOIUrl":"https://doi.org/10.1515/reveh-2025-0080","url":null,"abstract":"Introduction: There is a great deal of evidence that cadmium toxicity can have a significant impact on nutritional deficiencies, particularly iron deficiency. Therefore, in this study, we aimed to investigate the effect of cadmium toxicity on iron deficiency by meta-analysis method in order to clarify the previously obtained results.Content: Web of Science, Scopus, and Pubmed databases were used for systematic search until December 17th, 2024. RevMan 5.4 software was used to perform meta-analysis.Summary: Six studies were suitable for evaluating environmental/occupational cadmium exposure. In this analysis, serum cadmium levels were meaningfully higher in the cadmium-exposed groups (p=0.0005), while serum iron levels were meaningfully lower (p=0.0004). Forty-five studies were evaluated to include all diseases in which serum cadmium and serum iron levels were measured and included. According to this analysis, serum cadmium levels were meaningfully higher in case groups than in healthy controls (p<0.00001), while serum iron levels were meaningfully lower (p<0.00001). We also performed subgroup analysis exclusively for cancer patients and observed that serum cadmium levels were significantly elevated in cancer patients (p<0.00001), whereas serum iron levels were significantly decreased (p<0.00001).Outlook: This is the first meta-analysis assessing the association between cadmium toxicity and iron deficiency. Our findings demonstrate that cadmium may be effective in triggering iron deficiency anemia and inflammation-induced anemia by impairing iron metabolism. However, it should be noted that more detailed studies are needed to clarify these effects of cadmium.","PeriodicalId":21165,"journal":{"name":"Reviews on Environmental Health","volume":" ","pages":""},"PeriodicalIF":4.5,"publicationDate":"2026-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146228396","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Editorial: A new chapter in the lasting legacy of Reviews on Environmental Health. 社论：《环境卫生评论》持久遗产的新篇章。

IF 4.5 4区医学

Reviews on Environmental Health Pub Date : 2026-02-17 Print Date: 2026-03-26 DOI: 10.1515/reveh-2026-0005

Kelly G Pennell

引用次数: 0

The rising tide of plastic pollutants: implications for schizophrenia onset, a mini-review. 塑料污染物的上升趋势：对精神分裂症发病的影响，一篇小型综述。

IF 4.5 4区医学

Reviews on Environmental Health Pub Date : 2026-01-09 Print Date: 2026-03-26 DOI: 10.1515/reveh-2025-0106

Andrea Gogos, Alicia Bjorksten, Wah Chin Boon, Anne-Louise Ponsonby

{"title":"The rising tide of plastic pollutants: implications for schizophrenia onset, a mini-review.","authors":"Andrea Gogos, Alicia Bjorksten, Wah Chin Boon, Anne-Louise Ponsonby","doi":"10.1515/reveh-2025-0106","DOIUrl":"10.1515/reveh-2025-0106","url":null,"abstract":"The increasing exposure to manufactured environmental pollutants, especially plastics, is linked to adverse neurological effects. While prenatal exposure to plastics has been associated with neurodevelopmental disorders, particularly autism, the role of this exposure in schizophrenia remains under-investigated. This narrative mini-review examines the potential impact of endocrine-disrupting plastics, e.g. bisphenols and phthalates, on schizophrenia onset risk. These chemicals are ubiquitous and pervasive neurotoxicants, implicated in neuroinflammation - a key feature of schizophrenia. Additionally, microplastics have been detected in human brains, raising concerns about their potential long-term impact on neurological health. Despite the growing evidence of plastic-induced neurodevelopmental harm, this issue has been neglected for schizophrenia, with scarce human or valid animal model literature available. Limited studies indicate that plastic chemicals cause behavioural deficits, hormonal dysregulation and altered brain function relevant to schizophrenia. Cumulative exposure to multiple plastic chemicals over the life course necessitates carefully designed approaches. Future studies should investigate the mechanisms by which plastics contribute to schizophrenia risk. Epidemiological research with multi-omic approaches is needed to strengthen regulatory action and inform exposure prevention strategies particularly in high-risk populations. Given the increasing burden of environmental pollutants, urgent attention is required to address their role in neurodevelopmental disorders, particularly schizophrenia.","PeriodicalId":21165,"journal":{"name":"Reviews on Environmental Health","volume":" ","pages":"2-11"},"PeriodicalIF":4.5,"publicationDate":"2026-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145934816","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0