Research and Reports in Tropical Medicine最新文献

{"title":"Retrospective Analysis of Malaria Cases in a Potentially High Endemic Area of Morogoro Rural District, Eastern Tanzania.","authors":"Joseph N Aikambe,&nbsp;Ladslaus L Mnyone","doi":"10.2147/RRTM.S254577","DOIUrl":"https://doi.org/10.2147/RRTM.S254577","url":null,"abstract":"<p><strong>Background: </strong>Malaria is increasingly characterized by appreciable fine-scale variability in ecology and topography, and it is likely that we are missing some salient foci with unprecedented malaria transmission intensity in different parts of Tanzania. Therefore, efforts aimed at identifying area-specific malaria situation and intervening are needed to preserve the realized health gains and achieve elimination. Mkuyuni and Kiroka, adjacent wards within Morogoro Rural District, are purported to form one of such foci.</p><p><strong>Patients and methods: </strong>A retrospective study was conducted to determine six-year (2014-2019) malaria prevalence rates based on outpatients and laboratory registers obtained from two health facilities, one per ward, carrying out diagnosis of malaria either through microscopy or malaria rapid diagnostic test (mRDT). These data were checked for completeness before carrying out statistical analysis.</p><p><strong>Results: </strong>Overall, 35,386 (46.19%) out of 76,604 patients were positive for malaria. The average proportion of malaria cases was significantly higher in Mkuyuni (51.23%; n=19,438) than Kiroka (41.21%; n = 15,938) (P <0.001). Females were more affected than males (P <0.001);, and irrespective of the sex, most malaria cases were recorded in children <5 years of age (P <0.001) except at Mkuyuni. Malaria was recorded virtually all year round; however, the highest proportion of cases was recorded in April and July (P <0.001).</p><p><strong>Conclusion: </strong>This study revealed high malaria endemicity in Mkuyuni and Kiroka, with prevalence rate as high as 60.98%, which is far higher than the overall national average prevalence of 9%. More studies are needed in these and other putatively high endemic foci in Tanzania in order to inform the future course of action in disease surveillance and control.</p>","PeriodicalId":21138,"journal":{"name":"Research and Reports in Tropical Medicine","volume":"11 ","pages":"37-44"},"PeriodicalIF":3.1,"publicationDate":"2020-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2147/RRTM.S254577","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38102936","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Basic Coagulation Profiles and Platelet Count Among <i>Schistosoma mansoni</i>-Infected Adults Attending Sanja Primary Hospital, Northwest Ethiopia.","authors":"Tahir Eyayu, Ayalew Jejaw Zeleke, Masresha Seyoum, Ligabaw Worku","doi":"10.2147/RRTM.S244912","DOIUrl":"10.2147/RRTM.S244912","url":null,"abstract":"<p><strong>Purpose: </strong>To assess basic coagulation profiles and platelet count among <i>Schistosoma mansoni</i>-infected and non-infected adults.</p><p><strong>Patients and methods: </strong>A comparative cross-sectional study was conducted from February to April 2019 at Sanja Primary Hospital, northwest Ethiopia. A total of 200 adults (100 cases and 100 controls) were enrolled using convenient sampling technique. Both wet mount and Kato-Katz techniques were performed using a stool sample. The venous blood sample was collected to perform platelet count, basic coagulation and serological tests. The data were coded and entered into EpiData Manager (v4.4.2.1) and analyzed using SPSS version 20. Nonparametric tests were used during data analysis. <i>P</i>-value less than 0.05 was considered as statistically significant.</p><p><strong>Results: </strong>Prothrombin time (PT), activated partial thromboplastin time (APTT) and international normalization ratio (INR) were significantly higher while the platelet count was significantly lower in <i>S. mansoni</i>-infected than healthy adults (<i>P</i> <0.001). There were statistically significant differences in the median [IQR] value of PT, APTT, INR and platelet count between light, moderate and heavy infected groups (<i>P</i> <0.05). Infection intensity had a positive correlation with basic coagulation profiles and a negative correlation with platelet count (<i>P</i> <0.05) of <i>S. mansoni</i>-infected adults.</p><p><strong>Conclusion: </strong>The prevalence of coagulation abnormality was higher in <i>S. mansoni</i>-infected adults than healthy controls. Coagulation test and platelet count should be used to monitor and manage schistosomiasis-related complications.</p>","PeriodicalId":21138,"journal":{"name":"Research and Reports in Tropical Medicine","volume":"11 ","pages":"27-36"},"PeriodicalIF":3.1,"publicationDate":"2020-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/ca/65/rrtm-11-27.PMC7184861.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37901663","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Parasitic Contamination of Fruits and Vegetables Collected from Local Markets of Bahir Dar City, Northwest Ethiopia.","authors":"Getaneh Alemu, Mezgebu Nega, Megbaru Alemu","doi":"10.2147/RRTM.S244737","DOIUrl":"10.2147/RRTM.S244737","url":null,"abstract":"<p><strong>Background: </strong>Fruits and vegetables, which are consumed raw, act as potential sources for the spread of various parasitic diseases. The rate of contamination and species of contaminant parasites varies based on climatic, ecological, and human factors. Therefore, local data about the contamination status and predisposing factors augments efforts for successful control of parasitic diseases.</p><p><strong>Methods: </strong>A cross-sectional study was conducted on fruits and vegetables collected from local markets of Bahir Dar city from February to May 2019. A total of 384 samples were purchased from three randomly selected markets. Data on sociodemographic characteristics of vendors and factors associated with contamination of fruits and vegetables were collected using a structured questionnaire. About 200 g of fruit and vegetable samples were processed for parasites using direct wet mount and modified Zeihl-Neelson staining techniques following standard protocols. All data were analyzed using SPSS version 23.</p><p><strong>Results: </strong>Among a total of 384 fruit and vegetable samples purchased from 112 vendors, 150 (39.1%) were contaminated with at least one species of parasite. Lettuce (56.4%) and mango (16.7%) were the most and the least commonly contaminated items respectively. Larva of <i>Strongyloides</i> species (13.5%) was the most frequently detected parasite followed by cysts of <i>Entamoeba histolytica/E. dispar</i> (12.8%). Contamination was more common in vegetables than fruits (AOR=2.968, <i>p</i><0.001). Fruits and vegetables purchased from vendors with untrimmed fingernails (AOR=1.966, <i>p</i>=0.006), directly delivered from farmers (AOR=1.883, <i>p</i>=0.040), displayed in bucket with water (AOR=2.676, <i>p</i>=0.017) and those displayed without washing (AOR=5.511, <i>p</i><0.001) were significantly associated with parasitic contamination.</p><p><strong>Conclusion: </strong>The level of parasitic contamination of fruits and vegetables in Bahir Dar city is of public health importance. Hence, the public health sector should create public awareness in order to reduce parasitic transmission via fruits and vegetables.</p>","PeriodicalId":21138,"journal":{"name":"Research and Reports in Tropical Medicine","volume":"11 ","pages":"17-25"},"PeriodicalIF":3.1,"publicationDate":"2020-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/e8/62/rrtm-11-17.PMC7127876.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37825331","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Geographic Accessibility, Readiness, and Barriers of Health Facilities to Offer Tuberculosis Services in East Gojjam Zone, Ethiopia: A Convergent Parallel Design.","authors":"Mulusew Andualem Asemahagn,&nbsp;Getu Degu Alene,&nbsp;Solomon Abebe Yimer","doi":"10.2147/RRTM.S233052","DOIUrl":"https://doi.org/10.2147/RRTM.S233052","url":null,"abstract":"<p><strong>Background: </strong>Tuberculosis (TB) remains a foremost global public health threat. Active TB control needs geographically accessible health facilities that have quality diagnostics, equipment, supplies, medicines, and staff.</p><p><strong>Objective: </strong>This study aimed at assessing the geographic distribution, physical accessibility, readiness and barriers of health facilities for TB services in East Gojjam zone, Ethiopia.</p><p><strong>Methods: </strong>A convergent parallel design was applied using health facility and geographic data. Data on facility attributes, service availability and readiness were collected by inteviewing TB officers, laboratory heads and onsite facility visits. Coordinates of health facilities and kebele centroids were collected by GPS. We used ArcGIS 10.6 to measure Euclidean distance from each kebele centroids to the nearest health facility. Descriptive statistics were computed by using SPSS version 25. Barriers to TB service readiness were explored by in-depth interviews. NVivo12 was used to thematically analyze the qualitative data.</p><p><strong>Results: </strong>The overall TB health service coverage (THSC) was 23% (ranging: 10-85%). The mean distance from the nearest health facility was 8km (ranging: 0.5-16km). About 132 (32%) kebeles had poor geographic accessibility to TB services (over 10km distance from the nearest health facility) and had poor facility readiness. Although 114 (95%) health facilities offered at least one TB service, 44 (38.6%) of them had no sputum smear microscopy. The overall TB readiness index was 63.5%: first-line anti-TB drugs (97%), diagnostics (63%), trained staffs, diagnostic and treatment guidelines (53%) and laboratory supplies (41%). Lack of health workers (laboratory personnel), inadequate budget, poor management practice and TB program support, inadequate TB commodity suppliers, and less accessible geographic locations of health facilities were identified as barriers to TB service readiness distribution.</p><p><strong>Conclusion: </strong>Considerable proportion of the population in the study area  have poor access to quality TB diagnostic services due to low THSC and poor facility readiness. Barriers to TB service availability and readiness were health system related. Regular refresher training of health workers on TB, creating mechanisms to attract laboratory personnel to work in the study area and scaling up of sputum smear microscopy services, establishing an efficient mechanism for procurement, distribution, utilization and reporting of TB commodity supplies, and good management practices are crucial to enhance TB service readiness in the study zone.</p>","PeriodicalId":21138,"journal":{"name":"Research and Reports in Tropical Medicine","volume":"11 ","pages":"3-16"},"PeriodicalIF":3.1,"publicationDate":"2020-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2147/RRTM.S233052","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37678727","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Erratum: <i>Culex quinquefasciatus</i> Egg Membrane Alteration and Ovicidal Activity of <i>Cipadessa baccifera</i> (Roth) Plant Extracts Compared to Synthetic Insect Growth Regulators [Corrigendum].","authors":"","doi":"10.2147/RRTM.S242999","DOIUrl":"https://doi.org/10.2147/RRTM.S242999","url":null,"abstract":"<p><p>[This corrects the article DOI: 10.2147/RRTM.S227590.].</p>","PeriodicalId":21138,"journal":{"name":"Research and Reports in Tropical Medicine","volume":"11 ","pages":"1"},"PeriodicalIF":3.1,"publicationDate":"2020-01-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2147/RRTM.S242999","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37612196","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Schistosomiasis: Still a Cause of Significant Morbidity and Mortality.","authors":"Mohamud A Verjee","doi":"10.2147/RRTM.S204345","DOIUrl":"10.2147/RRTM.S204345","url":null,"abstract":"<p><p>Tropical diseases remain severe threats to global health with acute or chronic debility. Public health issues are regularly monitored and reported by the WHO. Conditions with high prevalence and virulence such as Schistosomiasis or Malaria still need active treatment. Advances over the decades in the treatment and management of Schistosomiasis have reduced morbidity and mortality in patients. However, poverty, adverse environments, lack of education and awareness, with parasites and vectors that can thrive if uncontrolled, remain issues for the successful global eradication of Schistosomiasis. From the disease's discovery in 1850, the author relates historical details to its current status. Several countries previously affected, including Japan and Tunisia, have eliminated the disease while others seek the same goal. Africa remains the most severely affected continent with vulnerable women and children, although the infection persists in South America and the Far East of Asia as well. Realistic improvements for continuing health conditions are vogue and emphasized for those at risk or afflicted by the infection, illustrating success models of concerted efforts of extirpation. Constant proximity to infected water, with a parasite host, are hurdles in reducing exposure. Effective medication for acute treatment is available, and prophylaxis by vaccination is promising. Where endemic Schistosomiasis is prevalent, significant morbidity and mortality have far-reaching complications in multiple human organ systems, including irreversible pulmonary hypertension, renal, genitourinary, central nervous system conditions, and neoplasia. Two hundred and thirty million people are estimated to have contracted Schistosomiasis globally, with up to 700 million still at risk of infection, and 200,000 deaths occur annually. The disease may be more prevalent than thought after newer tests have shown increased sensitivity to pathological antigens. The author discusses infectivity risks, investigations, prognosis, treatment, and management, as well as morbidity and mortality.</p>","PeriodicalId":21138,"journal":{"name":"Research and Reports in Tropical Medicine","volume":"10 ","pages":"153-163"},"PeriodicalIF":3.1,"publicationDate":"2019-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2147/RRTM.S204345","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37677661","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Culex quinquefasciatus Egg Membrane Alteration and Ovicidal Activity of Cipadessa baccifera (Roth) Plant Extracts Compared to Synthetic Insect Growth Regulators","authors":"G. Ramkumar, S. Karthi, M. Shivakumar, E. Kweka","doi":"10.2147/RRTM.S227590","DOIUrl":"https://doi.org/10.2147/RRTM.S227590","url":null,"abstract":"Background Insecticide resistance among mosquito vectors for synthetic insecticides still remains a major problem for control efforts. This study assessed the ovicidal potential of crude solvent extracts from the medicinal plant Cipadessa baccifera comparatively to standard registered synthetic insect growth regulators (IGR) on freshly laid eggs of Culex quinquefasciatus. Method Five plant extracts were prepared using different solvents. The batches of eggs were exposed to different concentrations of each solvent extract comparatively to synthetic IGR. The hatched eggs of Cx. quinquefasciatus were subjected to different concentrations. The first instars that emerged from the eggs were counted daily. The egg hatching inhibition was observed 24, 48 and 72 hrs post treatment. The desiccation median time (DT50 and DT90) was calculated. Results The percent egg hatching inhibition was inversely proportional to the concentration of extracts. The morphological damage to the eggs was observed. Among five solvent extracts, acetone extracts showed the highest ovicidal activity. The changes in eggshell morphology were observed. The maximum ovicidal activity was observed in acetone extracts with DT50 value of 1.70 hrs (0.91–2.22). The methanol plant extract using gas chromatography-mass spectrometry identified 14 compounds. Conclusion These results suggest that the acetone extracts of C. baccifera have the potential to be used as an ovicidal agent for controlling mosquito populations in aquatic stages. The biodegradability of the extracts has the advantage of being eco-friendly.","PeriodicalId":21138,"journal":{"name":"Research and Reports in Tropical Medicine","volume":"10 1","pages":"145 - 151"},"PeriodicalIF":3.1,"publicationDate":"2019-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2147/RRTM.S227590","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47732988","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Soil-Transmitted Helminths And Other Intestinal Parasites Among Schoolchildren In Southern Ethiopia","authors":"Tilahun Eyamo, M. Girma, Tsegaye Alemayehu, Z. Bedewi","doi":"10.2147/RRTM.S210200","DOIUrl":"https://doi.org/10.2147/RRTM.S210200","url":null,"abstract":"Background Intestinal parasitic infections are the neglected tropical diseases that have a devastating effect and leads to malnutrition, morbidity and mortality in schoolchildren. The aim of this study was to determine the presence of soil-transmitted and other intestinal parasites among schoolchildren in southern Ethiopia. Methods A cross-sectional study was conducted in Gara Riketa primary school children at Hawassa Tula Sub-City, Southern Ethiopia from March 1 to April 20, 2017. The parent of participating children was interviewed with a structured questionnaire to collect the sociodemographic and risk factors data. Well-trained laboratory technicians were involved in the stool examination through direct and concentration methods. The data were entered and analyzed using SPSS version 20. ORs at 95% CI were considered as a statistically significant association with a p-value < 0.05. Results Out of 384 schoolchildren enrolled for the study, 260 (67.7%) were infected with one or more intestinal parasites. The predominantly identified parasite was Ascaris lumbricoides 146 (38.0%) followed by hookworms 12 (3.1%). The study showed that intestinal parasitic infections have a statistically significant association with being in 4th grade, the mother´s educational status (grade 9–12), having cut nails and washing hands before eating. Conclusion The rates of soil-transmitted helminths and other intestinal parasitic infections were very high in Gara Riketa primary school children. Based on the statistical analysis, hygiene and nail clipping are important habits to prevent infection with intestinal parasites.","PeriodicalId":21138,"journal":{"name":"Research and Reports in Tropical Medicine","volume":"10 1","pages":"137 - 143"},"PeriodicalIF":3.1,"publicationDate":"2019-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2147/RRTM.S210200","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45396055","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Factors associated with scabies outbreaks in primary schools in Ethiopia: a case–control study","authors":"Kefele Ejigu, Yusuf Haji, Alemayehu Toma Toma, B. T. Tadesse","doi":"10.2147/RRTM.S214724","DOIUrl":"https://doi.org/10.2147/RRTM.S214724","url":null,"abstract":"Background Scabies is a neglected tropical disease affecting more than 200 million people worldwide every year. Scabies in school adolescents and young adults could affect their school performance. The current study investigates the factors associated with an outbreak of scabies at primary schools in southern Ethiopia. Method A team of health professionals investigated an outbreak of scabies that occurred in primary schools from May 1 to 30, 2018. An unmatched case–control study was employed to assess factors which predisposed for the scabies outbreak. Cases of scabies were individuals having a skin lesion compatible with the WHO case definitions of scabies. Controls were from the same locality with no skin lesions. Data on sociodemographic and behavioral variables were collected using questionnaires. Data on clinical presentations of scabies among cases were recorded by two trained and experienced health professionals. Factors associated with scabies were assessed using bivariate and multivariate logistic regression, and strength of association was described using odds ratio (OR) and 95% confidence intervals (CIs). Results A total of 711 (237 cases and 474 controls) study subjects participated in the study. The mean age of study participants was 17.56±2.66 years. Poor knowledge about scabies, adjusted odds ratio (AOR)=4.32 (95% CI: 2.93, 6.36); male sex, AOR=2.69 (95% CI: 1.82, 3.96); and parental illiteracy, AOR =3.49 (95% CI: 2.06, 5.94) predicted scabies infestation. Additionally, socioeconomic variables like sharing clothes/beds or contact with others, AOR=3.12 (95% CI: 2.12, 4.59); low household annual income, AOR=2.13 (95% CI: 1.32, 3.44); and family size greater than five, AOR=1.77 (95% CI: 1.04, 3.01) were significantly associated with scabies infestation. Inaccessibility and poor utilization of water, AOR=1.64 (95% CI: 1.12, 2.40) and poor personal hygiene, AOR=1.69 (95% CI: 1.14, 2.51) were also factors independently associated with scabies. Conclusion Modifiable risk factors such as personal hygiene and literacy level were found to be independent predictors of scabies infestation. Access to and utilization of water were also important predictors. Strategies for poverty alleviation and awareness creation on personal hygiene and efficient use of water are recommended for effective prevention of scabies infestation in closed institutions.","PeriodicalId":21138,"journal":{"name":"Research and Reports in Tropical Medicine","volume":"10 1","pages":"119 - 127"},"PeriodicalIF":3.1,"publicationDate":"2019-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2147/RRTM.S214724","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45147607","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Serological evidence of dengue fever and its associated factors in health facilities in the Borena Zone, South Ethiopia","authors":"E. Geleta","doi":"10.2147/RRTM.S218586","DOIUrl":"https://doi.org/10.2147/RRTM.S218586","url":null,"abstract":"Background Dengue fever (DF) is a re-emerging public health threat in Ethiopia. Yet, little is known about the epidemiology and risk factors of dengue infection in the region. In this study, the seroprevalence and associated risk factors of dengue virus infection were assessed in the Borena Zone health facilities. Methods A hospital-based cross-sectional study was conducted from July to August 2016. A total of 519 consecutive acute febrile patients attending the outpatient departments of Teltelle Health Center, Yabello and Moyale Hospital were enrolled. Data on socio-demographic and environmental risk factors were collected using a structured questionnaire. Three to five milliliter blood samples were collected from all participants and screened for dengue virus exposure using indirect immunofluorescent assay. Results The overall prevalence of anti-DENV IgG and IgM was 22.9% and 7.9%, respectively. DF serostatus was influenced by gender (adjusted odd ratio (AOR)=1.72; 95% CI 1.01–2.94), place of residence (AOR=2.69; 95%CL 1.55–4.64) that had a higher rate of exposure and recalling of a recent mosquito bite (AOR=2.98; 95% CI 1.51–5.89) probably imply recent and/or ongoing active transmission. Conclusion This study showed that DF could potentially emerge as a public health threat in the study area. In addition to that, the observed low awareness of participants underlines the urgent need for further community-based studies to determine the environmental, and host factors that determine the extent of exposure to dengue virus infection in the area for appropriate control and prevention planning.","PeriodicalId":21138,"journal":{"name":"Research and Reports in Tropical Medicine","volume":"10 1","pages":"129 - 136"},"PeriodicalIF":3.1,"publicationDate":"2019-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2147/RRTM.S218586","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48716678","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}