Reviews in Endocrine and Metabolic Disorders最新文献_第4页

The gut microbiome and heart failure: A better gut for a better heart 肠道微生物群与心力衰竭:肠道好，心脏好

Reviews in Endocrine and Metabolic Disorders Pub Date : 2019-11-09 DOI: 10.1007/s11154-019-09519-7

M. Branchereau, R. Burcelin, C. Heymes

引用次数: 32

Efficacy and safety of very low calorie ketogenic diet (VLCKD) in patients with overweight and obesity: A systematic review and meta-analysis 极低热量生酮饮食(VLCKD)对超重和肥胖患者的疗效和安全性:一项系统综述和荟萃分析

Reviews in Endocrine and Metabolic Disorders Pub Date : 2019-11-09 DOI: 10.1007/s11154-019-09514-y

M. Castellana, E. Conte, A. Cignarelli, Sebastio Perrini, A. Giustina, L. Giovanella, F. Giorgino, P. Trimboli

引用次数: 118

Clinical applications of (epi)genetics in gastroenteropancreatic neuroendocrine neoplasms: Moving towards liquid biopsies. （epi）遗传学在胃肠胰神经内分泌肿瘤中的临床应用：向液体活检方向发展。

Reviews in Endocrine and Metabolic Disorders Pub Date : 2019-09-01 DOI: 10.1007/s11154-019-09508-w

Gitta Boons, Timon Vandamme, Marc Peeters, Guy Van Camp, Ken Op de Beeck

{"title":"Clinical applications of (epi)genetics in gastroenteropancreatic neuroendocrine neoplasms: Moving towards liquid biopsies.","authors":"Gitta Boons, Timon Vandamme, Marc Peeters, Guy Van Camp, Ken Op de Beeck","doi":"10.1007/s11154-019-09508-w","DOIUrl":"10.1007/s11154-019-09508-w","url":null,"abstract":"High-throughput analysis, including next-generation sequencing and microarrays, have strongly improved our understanding of cancer biology. However, genomic data on rare cancer types, such as neuroendocrine neoplasms, has been lagging behind. Neuroendocrine neoplasms (NENs) develop from endocrine cells spread throughout the body and are highly heterogeneous in biological behavior. In this challenging disease, there is an urgent need for new therapies and new diagnostic, prognostic, follow-up and predictive biomarkers to aid patient management. The last decade, molecular data on neuroendocrine neoplasms of the gastrointestinal tract and pancreas, termed gastroenteropancreatic NENs (GEP-NENs), has strongly expanded. The aim of this review is to give an overview of the recent advances on (epi)genetic level and highlight their clinical applications to address the current needs in GEP-NENs. We illustrate how molecular alterations can be and are being used as therapeutic targets, how mutations in DAXX/ATRX and copy number variations could be used as prognostic biomarkers, how far we are in identifying predictive biomarkers and how genetics can contribute to GEP-NEN classification. Finally, we discuss recent studies on liquid biopsies in the field of GEP-NENs and illustrate how liquid biopsies can play a role in patient management. In conclusion, molecular studies have suggested multiple potential biomarkers, but further validation is ongoing.","PeriodicalId":21105,"journal":{"name":"Reviews in Endocrine and Metabolic Disorders","volume":"22 1","pages":"333-351"},"PeriodicalIF":0.0,"publicationDate":"2019-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81208105","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Neuroendocrinological mechanisms underlying impulsive and compulsive behaviors in obesity: a narrative review of fMRI studies. 肥胖症中冲动和强迫行为的神经内分泌机制：功能性磁共振成像研究的叙述性回顾。

Reviews in Endocrine and Metabolic Disorders Pub Date : 2019-09-01 DOI: 10.1007/s11154-019-09515-x

Trevor Steward, Romina Miranda-Olivos, Carles Soriano-Mas, Fernando Fernández-Aranda

{"title":"Neuroendocrinological mechanisms underlying impulsive and compulsive behaviors in obesity: a narrative review of fMRI studies.","authors":"Trevor Steward, Romina Miranda-Olivos, Carles Soriano-Mas, Fernando Fernández-Aranda","doi":"10.1007/s11154-019-09515-x","DOIUrl":"10.1007/s11154-019-09515-x","url":null,"abstract":"Impulsivity and compulsivity are multidimensional constructs that are increasingly considered determinants of obesity. Studies using functional magnetic resonance imaging (fMRI) have provided insight on how differences in brain response during tasks exploring facets of impulsivity and compulsivity relate to the ingestive behaviors that support the etiology and maintenance of obesity. In this narrative review, we provide an overview of neuroimaging studies exploring impulsivity and compulsivity factors as they relate to weight status. Special focus will be placed on studies examining the impulsivity-related dimensions of attentional bias, delayed gratification and emotion regulation. Discussions of compulsivity within the context of obesity will be restricted to fMRI studies investigating habit formation and response flexibility under shifting contingencies. Further, we will highlight neuroimaging research demonstrating how alterations in neuroendocrine functioning are linked to excessive food intake and may serve as a driver of the impulsive and compulsive behaviors observed in obesity. Research on the associations between brain response with neuroendocrine factors, such as insulin, peptide YY (PYY), leptin, ghrelin and glucagon-like peptide 1 (GLP-1), will be reviewed.","PeriodicalId":21105,"journal":{"name":"Reviews in Endocrine and Metabolic Disorders","volume":"1 1","pages":"263-272"},"PeriodicalIF":0.0,"publicationDate":"2019-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90557337","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Calcium citrate: from biochemistry and physiology to clinical applications 柠檬酸钙:从生物化学、生理学到临床应用

Reviews in Endocrine and Metabolic Disorders Pub Date : 2019-09-01 DOI: 10.1007/s11154-019-09520-0

A. Palermo, A. Naciu, G. Tabacco, S. Manfrini, P. Trimboli, F. Vescini, A. Falchetti

引用次数: 25

Adiponectin and PPAR: a setup for intricate crosstalk between obesity and non-alcoholic fatty liver disease. 脂联素和PPAR：肥胖症和非酒精性脂肪肝之间复杂的串扰机制

Reviews in Endocrine and Metabolic Disorders Pub Date : 2019-09-01 DOI: 10.1007/s11154-019-09510-2

Syeda Momna Ishtiaq, Haroon Rashid, Zulfia Hussain, Muhammad Imran Arshad, Junaid Ali Khan

{"title":"Adiponectin and PPAR: a setup for intricate crosstalk between obesity and non-alcoholic fatty liver disease.","authors":"Syeda Momna Ishtiaq, Haroon Rashid, Zulfia Hussain, Muhammad Imran Arshad, Junaid Ali Khan","doi":"10.1007/s11154-019-09510-2","DOIUrl":"10.1007/s11154-019-09510-2","url":null,"abstract":"Adiponectin, a soluble adipocytokine, plays an important role in the functioning of adipose tissue and in the regulation of inflammation, particularly hepatic inflammation. The adiponectin subsequently imparts a crucial role in metabolic and hepato-inflammatory diseases. The most recent evidences indicate that lipotoxicity-induced inflammation in the liver is associated with obesity-derived alterations and remolding in adipose tissue that culminates in most prevalent liver pathology named as non-alcoholic fatty liver disease (NAFLD). A comprehensive crosstalk of adiponectin and its cognate receptors, specifically adiponectin receptor-2 in the liver mediates ameliorative effects in obesity-induced NAFLD by interaction with hepatic peroxisome proliferator-activated receptors (PPARs). Recent studies highlight the implication of molecular mediators mainly involved in the pathogenesis of obesity and obesity-driven NAFLD, however, the plausible mechanisms remain elusive. The present review aimed at collating the data regarding mechanistic approaches of adiponectin and adiponectin-activated PPARs as well as PPAR-induced adiponectin levels in attenuation of hepatic lipoinflammation. Understanding the rapidly occurring adiponectin-mediated pathophysiological outcomes might be of importance in the development of new therapies that can potentially resolve obesity and obesity-associated NAFLD.","PeriodicalId":21105,"journal":{"name":"Reviews in Endocrine and Metabolic Disorders","volume":"37 1","pages":"253-261"},"PeriodicalIF":0.0,"publicationDate":"2019-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75636864","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Vitamin D in physiological and pathological aging: Lesson from centenarians 维生素D在生理性和病理性衰老中的作用:来自百岁老人的教训

Reviews in Endocrine and Metabolic Disorders Pub Date : 2019-09-01 DOI: 10.1007/s11154-019-09522-y

E. Ferri, M. Casati, M. Cesari, G. Vitale, B. Arosio

引用次数: 13

Vasopressin and Copeptin in health and disease 抗利尿激素和Copeptin在健康和疾病中的作用

Reviews in Endocrine and Metabolic Disorders Pub Date : 2019-09-01 DOI: 10.1007/s11154-019-09509-9

M. Christ-Crain

引用次数: 61

Risk of vertebral fractures in hypoparathyroidism 甲状旁腺功能减退症椎体骨折的风险

Reviews in Endocrine and Metabolic Disorders Pub Date : 2019-08-30 DOI: 10.1007/s11154-019-09507-x

A. Formenti, F. Tecilazich, R. Giubbini, A. Giustina

引用次数: 20

Current perspectives on the impact of clinical disease and biochemical control on comorbidities and quality of life in acromegaly 临床疾病和生化控制对肢端肥大症合并症和生活质量影响的最新观点

Reviews in Endocrine and Metabolic Disorders Pub Date : 2019-07-24 DOI: 10.1007/s11154-019-09506-y

F. Gatto, C. Campana, F. Cocchiara, G. Corica, M. Albertelli, M. Boschetti, G. Zona, Diego Criminelli, M. Giusti, D. Ferone

引用次数: 19