Recent patents on food, nutrition & agriculture最新文献

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Antifungal Mechanism of Rhodotorula mucilaginosa and Aureobasidium sp. nov. Isolated from Cerbera manghas L. against the Growth of Destructive Molds in Post Harvested Apples. 芒果粘红霉菌和小黑穗病菌对苹果采后破坏性霉菌生长的抑菌机理研究。
Recent patents on food, nutrition & agriculture Pub Date : 2020-01-01 DOI: 10.2174/2212798411666200423101159
Dalia Sukmawati, Andisa Shabrina, Reni Indrayanti, Tri Handayani Kurniati, Muktiningsih Nurjayadi, Iman Hidayat, Shabrina Nida Al Husna, Nuniek Ina Ratnaningtyas, Hesham El Enshasy, Daniel Joe Dailin, Abd El-Latif Hesham
{"title":"Antifungal Mechanism of Rhodotorula mucilaginosa and Aureobasidium sp. nov. Isolated from Cerbera manghas L. against the Growth of Destructive Molds in Post Harvested Apples.","authors":"Dalia Sukmawati,&nbsp;Andisa Shabrina,&nbsp;Reni Indrayanti,&nbsp;Tri Handayani Kurniati,&nbsp;Muktiningsih Nurjayadi,&nbsp;Iman Hidayat,&nbsp;Shabrina Nida Al Husna,&nbsp;Nuniek Ina Ratnaningtyas,&nbsp;Hesham El Enshasy,&nbsp;Daniel Joe Dailin,&nbsp;Abd El-Latif Hesham","doi":"10.2174/2212798411666200423101159","DOIUrl":"https://doi.org/10.2174/2212798411666200423101159","url":null,"abstract":"<p><strong>Background: </strong>Apples often experience postharvest damage due to being attacked by mold organisms. Several groups of molds such as Aspergillus sp., Penicilium expansum, Botrytis cinerea, and Venturia sp. can cause a serious postharvest disease exhibited as watery regions where areas of blue-green tufts of spores develop. Current methods using fungicides to control pathogenic fungi can cause resistance if applied in the long term. An alternative procedure using yeast as a biological agent has been found.</p><p><strong>Objective: </strong>The aim of this study is to screen potential yeast, which has the ability to inhibit the growth of Aspergillus brasielensis (isolate A1) and Aspergillus flavus section flavi (isolate A17) isolated from apple fruits.</p><p><strong>Methods: </strong>Antagonism test using YMA dual culture medium using in vitro assays and ITS rDNA identification were performed.</p><p><strong>Results: </strong>The result showed that 3 out of 19 yeast isolated from Cerbera manghas L, T1, T3 and T4, demonstrated the potential ability as a biocontrol agent. ITS rDNA identification demonstrated that T1 has a similarity to Rhodotorula mucilaginosa while T3 and T4 were identified as Aureobasidium sp. nov. The 3 isolates exhibited the ability to reduce the growth of A. brasiliensis sensu lato better than dithane 0.3% with a Disease Incidence (DI) of 100% and a Disease Severity (DS) value of 45%. Only isolate T1 and T3 were able to reduce decay symptoms in apples inoculated with A. flavus sensu lato (with DO and DS were 100% and 25%, respectively) compared to dithane pesticides 0.3%.</p><p><strong>Conclusion: </strong>This study indicated that competition between nutrients occurs between pathogenic molds and under-yeast in vitro and in vivo conditions. However, further studies in the future might be able to elucidate the 'killer' activity and interaction with the pathogen cells and the bio-product production using Rhodotorula mucilaginosa and Aureoubasidium namibiae strains to control postharvest diseases.</p>","PeriodicalId":21061,"journal":{"name":"Recent patents on food, nutrition & agriculture","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2174/2212798411666200423101159","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37864073","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Association Between Fat-soluble Vitamins and Lipid Profile in the Overweight Population. 超重人群脂溶性维生素与脂质关系的研究
Recent patents on food, nutrition & agriculture Pub Date : 2020-01-01 DOI: 10.2174/2212798410666190618152134
Sadegh Piran, Sahar Sarmasti, Mohammad Shabani, Naser Kakavandi, Bita Hosseni, Mohsen Khosravi, Shima Resaee, Elham Soltanmohammadi, Faezeh Naseri, Asghar Mohammadi, Mohammad Najafi
{"title":"Association Between Fat-soluble Vitamins and Lipid Profile in the Overweight Population.","authors":"Sadegh Piran,&nbsp;Sahar Sarmasti,&nbsp;Mohammad Shabani,&nbsp;Naser Kakavandi,&nbsp;Bita Hosseni,&nbsp;Mohsen Khosravi,&nbsp;Shima Resaee,&nbsp;Elham Soltanmohammadi,&nbsp;Faezeh Naseri,&nbsp;Asghar Mohammadi,&nbsp;Mohammad Najafi","doi":"10.2174/2212798410666190618152134","DOIUrl":"https://doi.org/10.2174/2212798410666190618152134","url":null,"abstract":"<p><strong>Background & aims: </strong>It is well-known that the coronary artery stenosis is related to lipid profile. This is a descriptive cross-sectional study to investigate the relationship between the serum fat-soluble vitamins (A, E and D), circulating proprotein convertase subtilisin/kexin type 9 (PCSK9), and lipid profile in the study population.</p><p><strong>Methods: </strong>A total of 120 overweight subjects were participated in this study. The circulating PCSK9 and vitamin D were measured by ELISA technique. The serum vitamin A and vitamin E amounts were simultaneously measured by the HPLC method. The Serum Small Dense LDLCholesterol (sdLDL-C) values were evaluated using heparin-Mg2+ precipitation technique. The lipid profile was measured by routine laboratory techniques.</p><p><strong>Results: </strong>The serum vitamin E values correlated significantly to vitamin A (r= 0.47, P= 0.0001), VLDL-C (r= 0.30, P= 0.002), total cholesterol (r= 0.309, P= 0.001), PCSK9 (r= 0.233, P= 0.01) and total triglyceride (r= 0.61, P= 0.0001) values. The circulating PCSK9 values correlated significantly to LDL-C (r= 0.17, P= 0.05) and total cholesterol (r= 0.23, P= 0.009) values. However, there were not correlations between the levels of serum D and A vitamins, the serum LDL-C, sdLDL-C and total cholesterol values.</p><p><strong>Conclusion: </strong>The data showed the correlations between serum vitamin E and PCSK9-related LDLC values lower than the normal range. Furthermore, the results suggested a nutritional need on the patents considering supplementation or fortification of vitamin E for the overweight subjects with higher LDL-C levels.</p>","PeriodicalId":21061,"journal":{"name":"Recent patents on food, nutrition & agriculture","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2174/2212798410666190618152134","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37360287","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Patents on Insect-based Feeds for Animals Including Companion Animals, and Terrestrial and Aquatic Livestock in Korea. “伴侣动物、陆生家畜、水生家畜用昆虫饲料专利”
Recent patents on food, nutrition & agriculture Pub Date : 2020-01-01 DOI: 10.2174/2212798410666190617160844
Jae-Suk Choi
{"title":"Patents on Insect-based Feeds for Animals Including Companion Animals, and Terrestrial and Aquatic Livestock in Korea.","authors":"Jae-Suk Choi","doi":"10.2174/2212798410666190617160844","DOIUrl":"https://doi.org/10.2174/2212798410666190617160844","url":null,"abstract":"<p><p>The demand for alternative protein sources by the livestock industry has increased substantially. Therefore, insects are being promoted as a novel nutrient source in animal feed. As detailed in this review, eleven patents related to feeding insects to terrestrial animals including livestock and companion animals have been commercially applied. Six and eight of the patents have been used to produce poultry and fish, and crustacean feed, respectively. The most promising species for industrial feed production was the black soldier fly (Hermetia illucens), the mealworm (Tenebrio molitor), and the two-spotted cricket (Gryllus bimaculatus). Regarding research areas of the patents reviewed here, studies on the composition and optimal mixing ratio of feeds and on insect rearing, harvesting, and post-harvest technologies were mainly performed for the industrial mass production of safe and functional animal feeds containing insects. Continuous scientific innovations and improved processing technologies will aid further advancements in this field. Therefore, this review offers insights to identify directions of future research and provides information on different insect-based feedstuffs for animals including terrestrial livestock, fish and shellfish, and companion animals, as also discussed in various patents.</p>","PeriodicalId":21061,"journal":{"name":"Recent patents on food, nutrition & agriculture","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2174/2212798410666190617160844","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37403941","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Application of Transglutaminase in Developing Cassava-based Wet Noodle for Quality and Shelf Life Improvement: A Review. 谷氨酰胺转胺酶在木薯湿面开发中的应用综述
Recent patents on food, nutrition & agriculture Pub Date : 2020-01-01 DOI: 10.2174/2212798411666200124105614
Warsono El Kiyat, Alvin Christopher, Angelina Rianti, Rizfi F Pari
{"title":"Application of Transglutaminase in Developing Cassava-based Wet Noodle for Quality and Shelf Life Improvement: A Review.","authors":"Warsono El Kiyat,&nbsp;Alvin Christopher,&nbsp;Angelina Rianti,&nbsp;Rizfi F Pari","doi":"10.2174/2212798411666200124105614","DOIUrl":"https://doi.org/10.2174/2212798411666200124105614","url":null,"abstract":"<p><p>Characteristic of cassava flour is relatively similar to wheat flour. Cassava flour has the potential to substitute 70-80% of wheat flour as the main ingredient for wet noodle production. Unfortunately, cassava flour has no gluten and lower protein content than wheat flour, which is important for the characteristic of a wet noodle. Therefore, transglutaminase (MTGase) is often applied in non-gluten products to improve its texture. This enzyme catalyzes the reaction between lysine and glutamine to form isopeptide cross-links. Moreover, the addition of MTGase to cassava-based wet noodle improves its texture and color. In addition, this effect gives better palatability for wet noodle. This enzyme can increase the shelf life of wet noodles and safe for our health. The present study demonstrates with patent and literature data the potential of MTGase in noodles based on cassava flour.</p>","PeriodicalId":21061,"journal":{"name":"Recent patents on food, nutrition & agriculture","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2174/2212798411666200124105614","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37576015","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Plant-microbial Interactions and their Role in Sustainable Agriculture and Sustainability of Agriculture Soils. 植物-微生物相互作用及其在可持续农业和农业土壤可持续性中的作用。
Recent patents on food, nutrition & agriculture Pub Date : 2020-01-01 DOI: 10.2174/221279841102200806152933
Naeem Khan
{"title":"Plant-microbial Interactions and their Role in Sustainable Agriculture and Sustainability of Agriculture Soils.","authors":"Naeem Khan","doi":"10.2174/221279841102200806152933","DOIUrl":"https://doi.org/10.2174/221279841102200806152933","url":null,"abstract":"Sustainable agriculture is the production of food or other plant or animal based products by using techniques that would protect environment, public health and animal welfare. Sustainable agriculture enable us to produce healthy food without harming natural resources. However, this agriculture depends on successful management of resources for agricultural in order to fulfil the requirements of increasing human population by improving the quality of crop plants and preserving natural resources. Plant growth promoting rhizobacteria (PGPR) are soil inhabitant bacteria that have some useful effects on soil properties and plant health. Plant growth promoting rhizobacteria can play a significant role to achieve sustainable agriculture. The use of PGPR is environment friendly way to enhance crop yields and to facilitate plant growth. PGPR gained more attraction because of their low cost and simple mode of action. They can be used singly or in combination but the combined use of PGPR always resulted incredible results on sustainable agriculture. PGPR are now used regularly to stimulate plant growth and productivity. However, the use of useful bacteria for sustainable agriculture and increase in crop yield needs the collection of capable root-colonizing bacteria which have confirmed plant growth potentials. Use of PGPR reduce the applications of chemical fertilizers which have unfriendly effects on environment. PGPR have the ability to produce broad variety of secondary metabolites, allelo-chemicals, which play pivotal role in plant sustainability and reactions to abiotic stresses. Besides PGPR, endophytic fungi can also play a key role in nutrient availability, protection of plants against various diseases and stresses and thus lead to sustainable agriculture. Endophytic fungi exist widely inside the healthy tissues of living plants, and are important components of plant micro-ecosystems. This Special Issue is focused on introducing the latest interesting findings on plant-microbe interactions and their role in plant growth and development, as well as in sustainable agriculture and sustainability of soils.","PeriodicalId":21061,"journal":{"name":"Recent patents on food, nutrition & agriculture","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38401005","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Optimization of Pectin Extraction from Sweet Potato Peels Using Citric Acid and its Emulsifying Properties. 柠檬酸提取甘薯皮中果胶的工艺优化及其乳化性能。
Recent patents on food, nutrition & agriculture Pub Date : 2020-01-01 DOI: 10.2174/2212798411666200207102051
Nurul Hazirah Hamidon, Dayang Norulfairuz Abang Zaidel, Yanti Maslina Mohd Jusoh
{"title":"Optimization of Pectin Extraction from Sweet Potato Peels Using Citric Acid and its Emulsifying Properties.","authors":"Nurul Hazirah Hamidon,&nbsp;Dayang Norulfairuz Abang Zaidel,&nbsp;Yanti Maslina Mohd Jusoh","doi":"10.2174/2212798411666200207102051","DOIUrl":"https://doi.org/10.2174/2212798411666200207102051","url":null,"abstract":"<p><strong>Background: </strong>Pectin is a natural polysaccharide that has been used widely as a stabilizer in food emulsion system.</p><p><strong>Objective: </strong>This study aimed to optimize the yield of pectin extracted from sweet potato residue and investigate its emulsifying properties.</p><p><strong>Methods: </strong>Response surface methodology (RSM) has been utilized to investigate the pectin extracted from sweet potato peels using citric acid as the extracting solvent. Investigation of the effect of different extraction conditions namely temperature (°C), time (min) and solution pH on pectin yield (%) were conducted. A Box-Benhken design with three levels of variation was used to optimize the extraction conditions.</p><p><strong>Results: </strong>The optimal conditions determined were temperature 76°C, time 64 min and pH 1.2 with 65.2% yield of pectin. The degree of esterification (DE) of the sweet potato pectin was determined using Fourier Transform Infrared (FTIR) Spectroscopy. The pectin is high-methoxyl pectin with DE of 58.5%. Emulsifying properties of sweet potato pectin were investigated by measuring the zeta-potential, particle size and creaming index with addition of 0.4 and 1.0 wt % pectin to the emulsion.</p><p><strong>Conclusion: </strong>Extraction using citric acid could improve the pectin yield. Improved emulsion stability was observed with the addition of the sweet potato pectin.</p>","PeriodicalId":21061,"journal":{"name":"Recent patents on food, nutrition & agriculture","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2174/2212798411666200207102051","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37619972","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Evaluation of the Cytotoxicity and Apoptotic Induction in Human Liver Cell Lines Exposed to Three Food Additives. 三种食品添加剂对人肝细胞的细胞毒性及诱导凋亡的影响。
Recent patents on food, nutrition & agriculture Pub Date : 2020-01-01 DOI: 10.2174/2212798411666200217124630
Ingy M El-Hefny, Neima K Al Senosy, Walaa G Hozayen, Amr E Ahmed, Ayman Diab, Wesam T Basal
{"title":"Evaluation of the Cytotoxicity and Apoptotic Induction in Human Liver Cell Lines Exposed to Three Food Additives.","authors":"Ingy M El-Hefny,&nbsp;Neima K Al Senosy,&nbsp;Walaa G Hozayen,&nbsp;Amr E Ahmed,&nbsp;Ayman Diab,&nbsp;Wesam T Basal","doi":"10.2174/2212798411666200217124630","DOIUrl":"https://doi.org/10.2174/2212798411666200217124630","url":null,"abstract":"<p><strong>Background: </strong>Rapid lifestyle, especially among people living in urban areas, has led to increasing reliance on the processed food market. Unfortunately, harmful effects caused by the excessive use of food additives in such type of industry are often neglected.</p><p><strong>Objective: </strong>This proposal investigates in vitro cytotoxic and apoptotic effects of three food preservatives commonly consumed in daily meals; sodium sulphite, boric acid, and benzoic acid.</p><p><strong>Methods: </strong>The effect of the three preservatives on cell viability was tested on two different cell lines; normal liver cell line THLE2 and human hepatocellular carcinoma cancer cell line HepG2 using MTT assay. Cell cycle arrest was measured using flow cytometry by propidium iodide. Measurement of expression levels of two central genes, p53 and bcl-2 that play key roles in cell cycle and apoptosis was carried out in HepG2 cells using real time-PCR.</p><p><strong>Results: </strong>Although the effect was more significantly realized in the HepG2 cell line, the viability of both cell lines was decreased by all of the three tested compounds. Flow cytometric analysis of HepG2 cells treated with sodium sulphite, boric acid, and benzoic acid has revealed an increase in G2/M phase cell cycle arrest. In Sodium sulphite and boric acid-treated cells, expression levels of p53 were up-regulated, while that of the Bcl2 was significantly down-regulated. On the other hand, Benzoic acid has shown an anti-apoptotic feature based on the increased expression levels of Bcl-2 in treated cells.</p><p><strong>Conclusion: </strong>In conclusion, all of the tested compounds have decreased the cell line viability and induced both cell cycle arrest and apoptotic events indicating their high potential of being cytotoxic and genotoxic materials.</p>","PeriodicalId":21061,"journal":{"name":"Recent patents on food, nutrition & agriculture","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2174/2212798411666200217124630","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37649724","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
The Use of Montmorillonite (MMT) in Food Nanocomposites: Methods of Incorporation, Characterization of MMT/Polymer Nanocomposites and Main Consequences in the Properties. 蒙脱土在食品纳米复合材料中的应用:蒙脱土/聚合物纳米复合材料的掺入方法、表征及其性能的主要影响。
Recent patents on food, nutrition & agriculture Pub Date : 2020-01-01 DOI: 10.2174/2212798410666190401160211
Fernanda Vilarinho, Malia Fátima Vaz, Ana Sanches Silva
{"title":"The Use of Montmorillonite (MMT) in Food Nanocomposites: Methods of Incorporation, Characterization of MMT/Polymer Nanocomposites and Main Consequences in the Properties.","authors":"Fernanda Vilarinho,&nbsp;Malia Fátima Vaz,&nbsp;Ana Sanches Silva","doi":"10.2174/2212798410666190401160211","DOIUrl":"https://doi.org/10.2174/2212798410666190401160211","url":null,"abstract":"<p><strong>Background: </strong>The clay Montmorillonite (MMT) is among the nanofillers more frequently used in food packaging. The uniform dispersion of nanoparticles in polymers confers considerable improvement of mechanical, thermal, optical, and/or barrier properties in polymer/clay nanocomposites.</p><p><strong>Objective: </strong>The aim is to ascertain the state of the art of the use of MMT for packaging purposes, with special emphasis on food applications.</p><p><strong>Methods: </strong>A literature review was carried out through recent papers and patents that focused on the incorporation of MMT in polymers.</p><p><strong>Results: </strong>This review emphasizes the interaction of MMT with polymers and their levels of incorporation in the nanocomposites. This work also highlights the analytical methodologies used for the characterization of the polymer/clay nanocomposites and the main consequences of the fillers in the properties of nanocomposites. Challenges remain about increasing the compatibility between clays and biopolymers to promote their utilization in food packaging. New strategies for immobilization of oxides, enzymes, essential oils, and other bioactive compounds are needed.</p><p><strong>Conclusion: </strong>MMT-based composite materials are promising to be used in intelligent and active packaging.</p>","PeriodicalId":21061,"journal":{"name":"Recent patents on food, nutrition & agriculture","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2174/2212798410666190401160211","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37270212","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 12
Chemical Constituents, Antioxidant, Anticholinesterase and Antiproliferative Effects of Algerian Pistacia atlantica Desf. Extracts. 阿尔及利亚黄连木的化学成分、抗氧化性、抗胆碱酯酶及抗增殖作用。提取物。
Recent patents on food, nutrition & agriculture Pub Date : 2020-01-01 DOI: 10.2174/2212798411666200207101502
Imene Achili, Amel Amrani, Chaouki Bensouici, Fatih Gül, Muhammed Altun, Ibrahim Demirtas, Djamila Zama, Fadila Benayache, Samir Benayache
{"title":"Chemical Constituents, Antioxidant, Anticholinesterase and Antiproliferative Effects of Algerian Pistacia atlantica Desf. Extracts.","authors":"Imene Achili,&nbsp;Amel Amrani,&nbsp;Chaouki Bensouici,&nbsp;Fatih Gül,&nbsp;Muhammed Altun,&nbsp;Ibrahim Demirtas,&nbsp;Djamila Zama,&nbsp;Fadila Benayache,&nbsp;Samir Benayache","doi":"10.2174/2212798411666200207101502","DOIUrl":"https://doi.org/10.2174/2212798411666200207101502","url":null,"abstract":"<p><strong>Background: </strong>Pistacia atlantica Desf. (Anacardiaceae) has various applications for dietetic and medicinal purposes.</p><p><strong>Objective: </strong>The aim of the present study was to evaluate antioxidant, antiproliferative and anticholinesterase activities of different extracts from leaf and stem of Pistacia atlantica Desf.</p><p><strong>Methods: </strong>The antioxidant activity was performed by four methods: DPPH, ABTS, CUPRAC and reducing power assays. Anti-cholinesterase activity was performed against acetylcholinesterase (AChE) and Butyrylcholinesterase (BuChE) enzymes. Antiproliferative assays were investigated against HeLa cell lines using xCELLigence RTCA instrument. The secondary metabolites composition was established by HPLC-TOF/MS analysis.</p><p><strong>Results: </strong>In DPPH, reducing power and in ABTS .+ scavenging activity, all the extracts showed strong inhibitory activity compared to synthetic antioxidants such as butylated hydroxytoluene (BHT) and butylated hydroxyanisole (BHA), in which the activities were almost equal to the two standards. The results were less significant in CUPRAC assay. The ethyl acetate (EtOAc) extracts exhibited the best antioxidant activity in all tests. Moreover, P. atlantica extracts inhibited AChE and BChE activities in a dose-dependent manner. The strongest AChE and BuChE inhibition activities were obtained for EtOAc extract of the stem (IC50 values 15.14±0.74 and 24.01±0.21 μg/mL, respectively) compared to galantamine (IC50 values 6.27±1.15 and 34.75±1.99 μg/mL, respectively). P. atlantica extracts also showed significant antiproleferative activity against HeLa cell lines, the best antiproleferative activity was obtained for the methanol and EtOAc extracts. The observed biological activities can be attributed to the presence of phenolic compounds and flavonoids in the extracts. The HPLC-TOF/MS analysis identified the presence of 22 phytochemicals. Gallic acid and rutin were the main compounds detected. Cichoric, gentisic, vanillic, protocatechuic and rosmarinic acids as well as catechin and quercetin were also present.</p><p><strong>Conclusion: </strong>This study demonstrated good antioxidant, anticholinesterase and antiproliferative activities of P. atlantica extracts, which opens up new possibilities for pharmaceutical and food industries.</p>","PeriodicalId":21061,"journal":{"name":"Recent patents on food, nutrition & agriculture","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2174/2212798411666200207101502","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37619973","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 8
Selecting Yield and Nutritional Traits in Sphenostylis stenocarpa Landraces for Food Improvement. 狭叶菊地方品种产量及营养性状的选择与改良。
Recent patents on food, nutrition & agriculture Pub Date : 2020-01-01 DOI: 10.2174/2212798410666190307131047
Charity Aremu, Micheal Abberton, Timothy Adebiyi, Abiola J Asaleye, Henry Inegbedion, Stephen Abolusoro, Aruna Adekiya, Christopher Aboyeji, OluGbenga Dunsin
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引用次数: 6
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