Radiation Measurements最新文献

{"title":"Evaluation of fluence-to-dose response function of neutron survey meter using singular value decomposition method","authors":"Ngoc-Thiem Le ,&nbsp;Ngoc-Quynh Nguyen ,&nbsp;Nguyen Ngoc Anh ,&nbsp;Hoai-Nam Tran ,&nbsp;Thiansin Liamsuwan ,&nbsp;Van-Loat Bui ,&nbsp;Tuan-Khai Nguyen ,&nbsp;Duc-Khue Pham ,&nbsp;Tien-Hung Dinh ,&nbsp;Van-Chung Cao","doi":"10.1016/j.radmeas.2024.107280","DOIUrl":"10.1016/j.radmeas.2024.107280","url":null,"abstract":"<div><p>This paper presents the evaluation of the fluence-to-ambient dose equivalent response function (referred to as F2D response function) of the Aloka TPS-451C neutron dose equivalent rate meter (hereafter referred to as a neutron meter) based on a singular value decomposition (SVD) approach. Measurements of neutron ambient dose equivalent rates, Ḣ<span><math><mrow><msup><mrow></mrow><mrow><mo>∗</mo></mrow></msup><mrow><mo>(</mo><mn>10</mn><mo>)</mo></mrow></mrow></math></span>, using the neutron meter were conducted in various neutron standard fields of ²⁴¹Am-Be source with different neutron fluence rate spectra. A series of Ḣ<span><math><mrow><msup><mrow></mrow><mrow><mo>∗</mo></mrow></msup><mrow><mo>(</mo><mn>10</mn><mo>)</mo></mrow></mrow></math></span> values and corresponding neutron fluence rate spectra were used as the input data for unfolding the F2D response function of the neutron meter. To verify the SVD-based method, the fluence response functions of a well-known Bonner sphere spectrometer system were unfolded using the SVD method, and the results were compared with those provided in the IAEA technical report No. 403. The SVD method was then applied to determine the F2D response function of the Aloka TPS-451C neutron meter with the use of the ICRP-74 F2D response function and that predicted in a previous work as initial guesses. The consistency between initial guesses and the SVD unfolded F2D response function of the Aloka TPS-451C neutron meter implies the reliability of the SVD method for determining the response functions of neutron meters.</p></div>","PeriodicalId":21055,"journal":{"name":"Radiation Measurements","volume":"178 ","pages":"Article 107280"},"PeriodicalIF":1.6,"publicationDate":"2024-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142095809","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sex differences in constructing dose-response calibration curves for micronuclei using cytokinesis-blocked micronucleus assay for radiation biological dosimetry in the Iranian population","authors":"R. Fardid ,&nbsp;N. Aghazadeh ,&nbsp;H. Parsaei ,&nbsp;M.A. Mosleh-Shirazi ,&nbsp;N. Zahraie","doi":"10.1016/j.radmeas.2024.107281","DOIUrl":"10.1016/j.radmeas.2024.107281","url":null,"abstract":"<div><p>Biological dosimetry, using chromosome damage biomarkers, can be considered as a key measure for radiation overexposure assessment. Therefore, for accurate dose estimation through biodosimetry, it's imperative for each biological dosimetry laboratory to establish its own specific dose-response calibration curve. In this research, the cytokinesis-blocked micronucleus (CBMN) assay was utilized to determine the frequencies of micronuclei (MN) per binucleated cell in human peripheral blood lymphocytes exposed to x-ray radiation using a LINAC (6 MV) at doses up to 4 Gy. The aim was to establish an in vitro dose-response calibration curve in our laboratory for the Iranian demographic by analyzing blood samples of ten participants (5 males and 5 females) through CABAS and Dose Estimate software. Our findings indicate an over-dispersion of the Poisson distribution in the pooled data across both sexes, coupled with a linear-quadratic increase in MN yield with dose which was particularly pronounced in the female group. The constructed dose-response curves for micronuclei yield are represented by equations Y= (0.0102 ± 0.0016) +(0.0296 ± 0.0054) D+(0.0232 ± 0.0017) D² and Y= (0.0084 ± 0.0010) +(0.0212 ± 0.0034) D+(0.0160 ± 0.0011) D² for the female groups, respectively. The alpha and beta coefficients, derived from the Dose Estimate software for each male and female group, were closely comparable with those obtained from the CABAS program and previous studies. The analysis of statistical parameters such as the Weighted Chi Squared (χ2) and p-value suggests that using distinct curves for each sex, rather than a unified biodosimetry formula for pooled data, ensures more accurate radiation dose estimates. Consequently, the findings of this study provide us with the assurance to utilize the derived calibration curve of MN for upcoming biological dosimetry needs in Iran. However, to enhance the reliability of results, it's essential to use biodosimetry with diverse assays and consider all clinical and physical parameters, given the limitations of cytogenetic assays.</p></div>","PeriodicalId":21055,"journal":{"name":"Radiation Measurements","volume":"178 ","pages":"Article 107281"},"PeriodicalIF":1.6,"publicationDate":"2024-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142122851","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development and validation of a comprehensive S-value database for small animal internal dosimetry in nuclear medicine using the DM_Bra mouse phantom","authors":"Khaoula Laazouzi ,&nbsp;Nícollas Gonçalves Cavedini ,&nbsp;Omaima Essaad Belhaj ,&nbsp;Maryam Hadouachi ,&nbsp;Hamid Boukhal ,&nbsp;El mahjoub Chakir ,&nbsp;Cristina Maria Moriguchi Jeckel ,&nbsp;Ana Maria Marques da Silva ,&nbsp;Maikol Salas-Ramirez","doi":"10.1016/j.radmeas.2024.107277","DOIUrl":"10.1016/j.radmeas.2024.107277","url":null,"abstract":"<div><p>Animal models are essential in the development of new radiopharmaceuticals in nuclear medicine, particularly for accurate dose calculation in small animal internal dosimetry. This study presents a comprehensive dataset of S-values for eleven commonly used radionuclides, calculated using the DM_Bra mouse phantom with the GATE Monte Carlo simulation code. To validate our approach, we first compared S-values obtained from the DM_Bra phantom with published values derived from the Digimouse phantom using a Tc-99 m source. The differences between the two phantoms range from 0.68% to 12.45% for self-irradiation and from 0.15% to 4.19% for cross-irradiation when the source is the stomach. These results demonstrate good agreement with reference data, supporting the reliability of our dataset. We then expanded our analysis by generating S-values for additional radionuclides, reflecting their usage in both diagnostic and therapeutic applications. Furthermore, to assess the impact of varying mouse geometries on S-values, the DM_Bra phantom (26.9 g) was rescaled to represent two other mouse sizes (19.6 g and 35.9 g). The statistical uncertainty associated with all these S-values remains below 2%. This study offers a valuable resource for internal dosimetry in mice, providing detailed S-values for a wide range of radionuclides and organ geometries, which can be used in small animal PET and SPECT studies.</p></div>","PeriodicalId":21055,"journal":{"name":"Radiation Measurements","volume":"178 ","pages":"Article 107277"},"PeriodicalIF":1.6,"publicationDate":"2024-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142137256","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative analysis of predose effects on TL and OSL signals in BeO dosimeters","authors":"Engin Aşlar","doi":"10.1016/j.radmeas.2024.107279","DOIUrl":"10.1016/j.radmeas.2024.107279","url":null,"abstract":"<div><p>This study investigates in detail the effects of predose on TL and OSL signals for BeO dosimeters. The TL and OSL signals were deconvoluted to each peak and component. As a result of deconvolution, the variations in the kinetic parameters (<em>E, T</em>_<em>max</em><em>, b</em>) for the TL signals and the lifetime values of the OSL signals were investigated. In addition, sensitivity changes according to predose were monitored for each peak and component. Finally, dose response curves were studied using the dose linearity index <em>(f(D</em>)) for each peak and component. Accordingly, the peak structures and kinetic parameters did not change according to the predose for the TL signal, whereas variations in the lifetime values for the OSL signal were observed, especially at the initial dose values (0.1 and 0.2 Gy). There was no change in sensitivity according to the predose for the total area condition although each peak and component exhibited independent behavior. Therefore, TL and OSL signals should be evaluated based on the total area in predose applications. The TL and OSL dose response curves exhibited different behaviors according to predose. TL dose response curves were not affected by the predose except for 1000 Gy, while the OSL dose response curves were affected by the predose considering the total area condition. The possible reason for the differences between the TL and OSL dose response curves is the significant transfer effect in the OSL signal at low doses, which results in greater changes at low doses compared to the TL signal. Also, thermal quenching effects may have resulted in lower intensity in the case of the TL signal. In future studies, preheating tests and thermal quenching corrections on TL peaks at high predoses may increase our understanding of deep trap interactions in BeO dosimeters.</p></div>","PeriodicalId":21055,"journal":{"name":"Radiation Measurements","volume":"178 ","pages":"Article 107279"},"PeriodicalIF":1.6,"publicationDate":"2024-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142095110","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The method of Pb-212 measurements in air with the application of the LSC technique","authors":"A. Grygier,&nbsp;S. Chałupnik","doi":"10.1016/j.radmeas.2024.107278","DOIUrl":"10.1016/j.radmeas.2024.107278","url":null,"abstract":"<div><p>This paper describes a method enabling the measurement of the potential alpha energy concentration (PAEC) of thoron decay products based on the determined concentration of lead ²¹²Pb (T_1/2 = 10.64 h) in the air [Lever et al., 2003]. A liquid scintillation spectrometer was used to determine the concentration of the ²¹²Pb isotope, and the sample was taken by pumping air through a filter where thoron decay products were stored. This method can be classified as integrating because the sample takes several hours, and the measurement results in one value for the entire sampling period. Measurements were carried out in laboratory conditions, in a climatic chamber where a constant supply of thoron was maintained, and in environmental conditions, in the basement of the family house and outdoors. Sampling took from 12 to 48 h. This article presents the preliminary results of the study. The obtained results were in the range of 170–195 Bq/m³ in the case of laboratory measurements and from 0.04 to 0.79 Bq/m³ in the case of environmental measurements. Based on the obtained results, the potential alpha energy concentration (PAEC) was calculated. The application of the low-level LS spectrometer allows for the achievement of a lower limit of detection (LLD) at level 0.04–0.05 Bq/m³, while the use of the portable LS spectrometer allows for the measurement of deficient ²¹²Pb concentrations in the range of 0.4–0.5 Bq/m³. The obtained results confirm that the method is suitable for determining the concentration of ²¹²Pb and, consequently, assessing exposure to thoron progeny.</p></div>","PeriodicalId":21055,"journal":{"name":"Radiation Measurements","volume":"178 ","pages":"Article 107278"},"PeriodicalIF":1.6,"publicationDate":"2024-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1350448724002269/pdfft?md5=21db9c90ac51a6ee728a58b6e34e4d33&pid=1-s2.0-S1350448724002269-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142130180","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Overview and current challenges at the Calibration Laboratory of the Paul Scherrer Institute","authors":"Malgorzata M. Kasprzak,&nbsp;Gernot Butterweck,&nbsp;Federico A. Geser,&nbsp;Alberto Stabilini,&nbsp;Malgorzata Sliz,&nbsp;Eduardo G. Yukihara,&nbsp;Sabine Mayer","doi":"10.1016/j.radmeas.2024.107273","DOIUrl":"10.1016/j.radmeas.2024.107273","url":null,"abstract":"<div><p>The Calibration Laboratory of the Paul Scherrer Institute (PSI) is a secondary calibration laboratory accredited by the Swiss Accreditation Service (SAS) in accordance with ISO 17025. It also acts as a verification body authorized by the Swiss Federal Institute of Metrology (METAS). The Laboratory is equipped with X-ray, gamma and neutron irradiation facilities, providing characterized reference radiation fields for gamma ¹³⁷Cs, ⁶⁰Co, narrow spectrum X-rays from N-15 to N-300 and neutron radionuclide sources ²⁵²Cf, ²⁵²Cf (D2O-moderated) and ²⁴¹Am-Be. The laboratory performs routine calibrations, organizes intercomparison measurements for individual monitoring services in Switzerland, and participates in various research projects, e.g., by performing irradiations in reference fields. For this reason, the proper characterization of reference radiation fields is of utmost importance for ensuring high quality irradiations and calibrations of personal dosemeters and radiation protection instruments. In this contribution, we provide an overview of the irradiation facilities at the Calibration Laboratory at PSI and discuss the challenges of characterizing reference radiation fields. In particular, we will discuss the factors affecting the determination of the distance between the source and irradiated dosemeters and detectors, as well as issues related to ²⁵²Cf decay and contribution of ²⁵⁰Cf. We will also demonstrate the use of Monte-Carlo simulations in determining the optimal position of the source and irradiation facility within the irradiation room.</p></div>","PeriodicalId":21055,"journal":{"name":"Radiation Measurements","volume":"177 ","pages":"Article 107273"},"PeriodicalIF":1.6,"publicationDate":"2024-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S135044872400221X/pdfft?md5=5082ce0621515fa238af136532218a91&pid=1-s2.0-S135044872400221X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142083638","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of radiation leakage in X-ray security inspection machine using a CZT spectrometer","authors":"Weifeng Zhu ,&nbsp;jinjie Wu ,&nbsp;Rui Zhao ,&nbsp;Xianqiang Tang ,&nbsp;Mengyu Li","doi":"10.1016/j.radmeas.2024.107274","DOIUrl":"10.1016/j.radmeas.2024.107274","url":null,"abstract":"<div><p>Leakage radiation from X-ray security inspection machines is important, and measurement based on ionization chamber or scintillator detector is widely used. The leakage radiation is closely related to the size and the passing time of the luggage, the lead equivalent, the opening angle of the lead curtain, and the response time of the measuring instrument. To characterize the distribution of leakage radiation from the X-ray security inspection machine accurately, a small-volume CZT(CdZnTe) spectrometer was used to measure the energy spectra at a distance of 5 cm from the surface of the inspection machine. By designing and controlling the opening angle of the lead curtain according to the size of the luggage passing through the entrance and exit, the radiation dose was determined based on the measured energy spectra combined with the G(E)-function method. The results show that the maximum relative deviation between the air kerma rate and the ambient dose equivalent rate calculated by the G(E) function method with the standard dose rate does not exceed ±5%. The maximum relative deviation of the dose rate linear verification in the ¹³⁷Cs radiation field is less than 2.5%. A calibrated CZT detector was utilized to measure the radiation leakage on the surface of the X-ray security inspection machine. It was discovered that the presence of the luggage items and the opening angle of the lead curtain will increase the leakage radiation dose on the surface of the security inspection machine system. This study provides a new approach for measuring scattered radiation of X-ray security inspection machines.</p></div>","PeriodicalId":21055,"journal":{"name":"Radiation Measurements","volume":"177 ","pages":"Article 107274"},"PeriodicalIF":1.6,"publicationDate":"2024-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142048666","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An efficient protocol for commissioning radiophotoluminescence dosimeters for radiotherapy dosimetry audits","authors":"Alexis Dimitriadis,&nbsp;Pavel Kazantsev,&nbsp;Egor Titovich,&nbsp;Geraldyne Ule-Duque,&nbsp;Roua Abdulrahim,&nbsp;Talent Magnus,&nbsp;Godfrey Azangwe,&nbsp;Jamema Swamidas","doi":"10.1016/j.radmeas.2024.107268","DOIUrl":"10.1016/j.radmeas.2024.107268","url":null,"abstract":"<div><h3>Purpose</h3><p>The aim of this study was to develop an efficient protocol for the commissioning of 1000 radiophotoluminescence dosimeters (RPLDs) for use in postal dosimetry audits in radiotherapy. This involved the determination of correction factors necessary to reduce measurement uncertainty and ensure accurate dose measurements.</p></div><div><h3>Methods</h3><p>The commissioning process started with the RPLDs subjected to a series of controlled irradiations to determine their individual nominal response. Experiments were also conducted to assess the influence of irradiation position, reading position, and ambient temperature on the dosimeter readings all which were accounted for calculating individual sensitivity correction factors (SCFs) for each dosimeter. Statistical analysis was performed to evaluate the variability of SCFs depending on normalization group. An additional investigation simulating different dosimetry audit batches was conducted to study the effect of SCF variability on dosimetry audit measurements.</p></div><div><h3>Results</h3><p>The adopted commissioning protocol required irradiation position correction factors (0.990–0.996), readout tray position correction factors (0.992–1.01) and room temperature corrections (∼0.4 % per ° C). This enabled the calculation of SCFs for a batch of 1000 RPLDs and the analysis found the majority of SCFs falling within the range of 0.985–1.015. The standard deviations of the SCF distributions were approximately 1% for all normalization groups. It was observed that SCFs normalized to the entire batch of 1000 dosimeters could be effectively used for smaller audit batches, with an additional uncertainty contribution of up to 0.2%. This minimal increase in uncertainty is acceptable within the context of dosimetry audits.</p></div><div><h3>Conclusions</h3><p>The developed protocol for commissioning RPLDs provides a reliable method for ensuring accurate dose measurements in postal radiotherapy dosimetry audits. The correction factors applied during the commissioning process were thoroughly described to effectively minimize measurement uncertainty. The findings support the use of SCFs normalized to large dosimeter batches for smaller audit groups, thereby streamlining the dosimetry audit process. Future research should focus on the long-term stability of SCFs to further enhance the reliability of RPLD-based dosimetry audits.</p></div>","PeriodicalId":21055,"journal":{"name":"Radiation Measurements","volume":"177 ","pages":"Article 107268"},"PeriodicalIF":1.6,"publicationDate":"2024-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1350448724002166/pdfft?md5=3d5a1fab4603f295917daa061022a4fd&pid=1-s2.0-S1350448724002166-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142007081","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Microdosimetric measurements for LET monitoring in proton therapy. The development of engineered mini-TEPCs for clinical applications: First results","authors":"A. Bianchi ,&nbsp;A. Selva ,&nbsp;F. Pasquato ,&nbsp;M. Rossignoli ,&nbsp;A. Minarello ,&nbsp;A. Fazzi ,&nbsp;V. Conte","doi":"10.1016/j.radmeas.2024.107271","DOIUrl":"10.1016/j.radmeas.2024.107271","url":null,"abstract":"<div><p>Innovative Treatment Planning Systems (TPS) in proton therapy based on a variable radiation quality with depth with respect to the conventional one with a fixed Relative Biological Effectiveness (RBE) of 1.1 are under study. Experimental methods are needed to verify the consistency between what is planned and what is delivered in terms of radiation quality. Microdosimetry studies the stochastics of the energy deposition process at micrometric and sub-micrometric level which is known to be related to the biological effectiveness of ionising radiation fields. For this reason, it is recognised by the scientific community that it is a useful tool to monitor the radiation quality of hadron therapy beams where the effectiveness varies with the penetration depth in patients. Detectors are needed to perform a microdosimetric characterization of a clinical beam and they need to satisfy specific requirements to enter the clinical practice as instruments for the Quality Assurance (QA). With this aim, at the Legnaro National Laboratories of the Italian National Institute for Nuclear Physics (LNL-INFN) a technological transfer project was carried out with the final goal of developing engineered miniaturized Tissue Equivalent Proportional Counters (mini-TEPCs) for clinical applications. This work presents the characterization performed on the new detectors and the results obtained in neutron and proton fields.</p></div>","PeriodicalId":21055,"journal":{"name":"Radiation Measurements","volume":"177 ","pages":"Article 107271"},"PeriodicalIF":1.6,"publicationDate":"2024-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1350448724002191/pdfft?md5=d70a9414d7c2b88031c0e392751645c6&pid=1-s2.0-S1350448724002191-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142002367","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Optically stimulated luminescence detectors for LET determination and dosimetry in ion beam therapy","authors":"Jeppe Brage Christensen ,&nbsp;Lily Bossin ,&nbsp;Iván Domingo Muñoz ,&nbsp;Christina Stengl ,&nbsp;José Vedelago ,&nbsp;Eduardo Gardenali Yukihara","doi":"10.1016/j.radmeas.2024.107270","DOIUrl":"10.1016/j.radmeas.2024.107270","url":null,"abstract":"<div><p>Optically stimulated luminescence detectors (OSLDs) have been utilized for various dosimetry applications for many years. The use of <span><math><mrow><msub><mrow><mtext>Al</mtext></mrow><mrow><mn>2</mn></mrow></msub><msub><mrow><mtext>O</mtext></mrow><mrow><mn>3</mn></mrow></msub><mtext>:C</mtext></mrow></math></span> OSLDs for proton dosimetry began over a decade ago, taking advantage of the correlation between the ionization density of the radiation field and the ratio of intensities of the material’s two emission bands. The correlation allows for determining both linear energy transfer (LET) and dose in proton beams, with corrections for ionization quenching derived from the LET. However, the previous methodology for proton dosimetry and simultaneous LET determination with <span><math><mrow><msub><mrow><mtext>Al</mtext></mrow><mrow><mn>2</mn></mrow></msub><msub><mrow><mtext>O</mtext></mrow><mrow><mn>3</mn></mrow></msub><mtext>:C</mtext></mrow></math></span> OSLDs was cumbersome and occasionally associated with large uncertainties, while carbon beam dosimetry posed further challenges due to an elevated LET.</p><p>This paper reviews the recent advancements in ion beam dosimetry and LET determination using OSLDs. Employing <span><math><mrow><msub><mrow><mtext>Al</mtext></mrow><mrow><mn>2</mn></mrow></msub><msub><mrow><mtext>O</mtext></mrow><mrow><mn>3</mn></mrow></msub><mtext>:C,Mg</mtext></mrow></math></span> OSLDs alongside improved, automatized read-out techniques, and the use of other radiation quality metrics than averaged LET, has removed most of the previous obstacles for ion beam dosimetry with OSLDs.</p><p>The feasibility of simultaneous LET determination and dosimetry in ion beams is demonstrated through two case studies involving realistic proton and carbon ion therapy scenarios.</p></div>","PeriodicalId":21055,"journal":{"name":"Radiation Measurements","volume":"177 ","pages":"Article 107270"},"PeriodicalIF":1.6,"publicationDate":"2024-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S135044872400218X/pdfft?md5=eef1b5ef38de505923681638d92ad27e&pid=1-s2.0-S135044872400218X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142048667","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}