Razavi International Journal of Medicine最新文献

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Coronary No-reflow Phenomenon: A Review of Therapeutic Pharmacological Agents 冠状动脉无血流现象:治疗药物综述
Razavi International Journal of Medicine Pub Date : 2020-10-01 DOI: 10.30483/RIJM.2020.254145.1002
Bahram Shahri, M. Vojdanparast
{"title":"Coronary No-reflow Phenomenon: A Review of Therapeutic Pharmacological Agents","authors":"Bahram Shahri, M. Vojdanparast","doi":"10.30483/RIJM.2020.254145.1002","DOIUrl":"https://doi.org/10.30483/RIJM.2020.254145.1002","url":null,"abstract":"Coronary no-reflow phenomenon (CNRP) is one of the leading catastrophic consequences of percutaneous coronary intervention (PCI). Although several preventive strategies have been advised, yet CNRP is not entirely controlled with pharmacological agents after diagnosis. This study is a review of therapeutic pharmacological agents used in various studies for post-PCI-CNRP. Several pharmacological agents have been introduced for reducing the burden of adverse outcome, before or during PCI. Although most of these agents have shown a remarkable effect on post-PCI CNRP incidence reduction, and it seems more powerful are still needed for a better validation of the results. It appears that intra lesion and distal intracoronary administrations would have a less systemic effect, and therefore may be safer than catheter injection. Moreover, adenosine, sodium nitroprusside, and calcium channel blockers are among the most routinely used methods. However, we believe that the best approach in treating or preventing no-reflow post-STMI might be combinational therapy. By the way, although there have been numerous studies on different agents capable of lessening the noreflow phenomenon, yet there is no exact guideline for choosing the most appropriate drug. A systematic review and meta-analysis on all available or practiced combinational pharmacotherapies to prevent PCI-related no-reflow are needed to suggest the most appropriate therapy.","PeriodicalId":20994,"journal":{"name":"Razavi International Journal of Medicine","volume":"8 1","pages":"1-7"},"PeriodicalIF":0.0,"publicationDate":"2020-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42468069","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Effect of Distress Tolerance and Emotional Self-Regulation on Complicated Grief with the Mediating Role of Social Support in Survivors of Kermanshah Earthquake 克尔曼沙地震幸存者痛苦容忍和情绪自我调节对复杂悲伤的影响及社会支持的中介作用
Razavi International Journal of Medicine Pub Date : 2020-10-01 DOI: 10.30483/RIJM.2020.254152.1007
A. Daneshvar, M. Madahi, H. Ahadi
{"title":"The Effect of Distress Tolerance and Emotional Self-Regulation on Complicated Grief with the Mediating Role of Social Support in Survivors of Kermanshah Earthquake","authors":"A. Daneshvar, M. Madahi, H. Ahadi","doi":"10.30483/RIJM.2020.254152.1007","DOIUrl":"https://doi.org/10.30483/RIJM.2020.254152.1007","url":null,"abstract":"Background: Bereavement is a person's response to loss that has a physical, psychological, or social aspect. Objectives: This study aimed to determine the effect of distress tolerance and emotional self-regulation on complicated grief with the mediating role of social support. Methods: The research method was descriptive and the research design was a structural equation modeling. The statistical population consisted of all survivors of the Kermanshah earthquake who are suffering from complicated grief in 2019 and are selected by convenience sampling method. Data obtained by Grief Experience Questionnaire (GEQ), Social Support Scale (MOS-SSS), Emotional self-regulation questionnaire and Distress Tolerance Questionnaire. Data were analyzed by the Pearson correlation coefficient and structural equation modeling using SPSS.22 and PLS2-SMART software. Results: The results of this study showed that the relationship between the variables of the study was significant, and distress tolerance, self-regulation, and social support have the ability to predict complicated grief (p <0.001). Also, social support has the mediating variable between distress tolerance and emotional self-regulation on complicated grief (p <0.001). Conclusion: According to the results of this study, earthquake survivors should be able to control the tolerance of grief after the earthquake by increasing their distress tolerance and emotional self-regulation and with social support from others.","PeriodicalId":20994,"journal":{"name":"Razavi International Journal of Medicine","volume":"8 1","pages":"33-39"},"PeriodicalIF":0.0,"publicationDate":"2020-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43469869","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effectiveness of Behavioral-Cognitive Therapy on Sexual Self-Esteem and Marital Commitment of Couples' with Troubled Relationships 行为认知疗法对问题夫妻性自尊和婚姻承诺的影响
Razavi International Journal of Medicine Pub Date : 2020-10-01 DOI: 10.30483/RIJM.2020.254172.1025
Alireza Khataei
{"title":"Effectiveness of Behavioral-Cognitive Therapy on Sexual Self-Esteem and Marital Commitment of Couples' with Troubled Relationships","authors":"Alireza Khataei","doi":"10.30483/RIJM.2020.254172.1025","DOIUrl":"https://doi.org/10.30483/RIJM.2020.254172.1025","url":null,"abstract":"Background: Health in families is rooted in sustenance and health of relationships between husbands and wives; and marital relationship is the core of families, disorders of which are threats to family survival. Objectives: The present study was aimed to examine the effectiveness of CBT on sexual self-esteem and marital commitment of couples' with troubled relationships in Tehran in 2017.Material and Methods: It was semi-experimental with a pre-test, post-test design as well as an experiment and a control group. The statistical population of the present research consisted of all couples with troubled relationships in Tehran, who were selected using a convenience sampling method and Cohen table for the sample size , and they were randomly divided into two groups: an experiment group (15 individuals) and a control group (15 individuals).The experiment group received ten 90-minute sessions of group CBT interventions, and the control group remained on a waitlist. The measurement tools of the research included Dobel Naha and Schwarz's sexual self-esteem questionnaire and Adams and Jones' marital commitment questionnaire. The analysis of the data obtained from implementing the questionnaires was done through SPSS-V22 software in two sections: descriptive and inferential . Results showed that CBT leads to an increase in sexual self-esteem in couples with troubled relationships. Therefore, it can be stated that group CBT is an effective method for improving self-esteem and marital commitment in couples. Conclusion: It can be stated that CBT helps family members to face problems effectively by resolving conflicts among family members and improving interpersonal relationships","PeriodicalId":20994,"journal":{"name":"Razavi International Journal of Medicine","volume":"8 1","pages":"22-27"},"PeriodicalIF":0.0,"publicationDate":"2020-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42328499","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Evaluation of How to Use Warfarin after Heart Valves Replacement Operations 心脏瓣膜置换术后华法林的应用评价
Razavi International Journal of Medicine Pub Date : 2020-10-01 DOI: 10.30483/RIJM.2020.254164.1018
Kambiz Alizadeh, M. Tabari, M. Sakhaei, Jamil Esfehanizadeh, Z. Tabrizi, A. Izanloo
{"title":"Evaluation of How to Use Warfarin after Heart Valves Replacement Operations","authors":"Kambiz Alizadeh, M. Tabari, M. Sakhaei, Jamil Esfehanizadeh, Z. Tabrizi, A. Izanloo","doi":"10.30483/RIJM.2020.254164.1018","DOIUrl":"https://doi.org/10.30483/RIJM.2020.254164.1018","url":null,"abstract":"Introduction Implantation of prosthetic valve requires a life time consumption of anticoagulation. Thrombotic and embolism complications as well as bleeding associated with anticoagulants are the leading cause of mortality and morbidity after heart valve surgery. Accordingly, this study is designed to explore and report the complications and factors related to usage of warfarin and constant check of prothrombin time and international normalized ratio. Method: This is an observational study in which the medical records of 100 patients with an average age of 47.9 ± 13.4 years undergoing surgery for replacement of heart valves were studied. All factors related to mortality and postoperative complications were extracted, and the patients were followed up for one year. Results: The results suggested that tricuspid valve insufficiency was significantly correlated other valvular defects. Nine patients died; one patient in the operating room, one patient in the ICU, one patient in the ward and six patients during the first year died after the surgery. Two of the patients needed redo-surgery in the first year. It should be noted that among patients receiving warfarin on a regular basis (n=81), no mortality was reported in a one-year fallow-up. Conclusion: In this study, out- of-hospital mortality only occurred in patients' irregular usage of warfarin and without follow-up coagulation tests. So, we conclude that in developing country, if we cannot follow and train the patients constantly for warfarin usage and blood tests, mechanical valve utilization would be concomitant with high risk complications.","PeriodicalId":20994,"journal":{"name":"Razavi International Journal of Medicine","volume":"8 1","pages":"14-17"},"PeriodicalIF":0.0,"publicationDate":"2020-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46247560","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Analysis of Biological Stress Indices in Patients with Gastrointestinal Cancer Based on Perceived Stress Mediated by Rumination using Structural Equation Modeling 基于反刍感知应激介导的胃肠道肿瘤患者生物应激指标分析
Razavi International Journal of Medicine Pub Date : 2020-10-01 DOI: 10.30483/RIJM.2020.254149.1004
Saeed Hashemzadeh, Mahmoud Borjali, Peyman Hassani Abharian
{"title":"Analysis of Biological Stress Indices in Patients with Gastrointestinal Cancer Based on Perceived Stress Mediated by Rumination using Structural Equation Modeling","authors":"Saeed Hashemzadeh, Mahmoud Borjali, Peyman Hassani Abharian","doi":"10.30483/RIJM.2020.254149.1004","DOIUrl":"https://doi.org/10.30483/RIJM.2020.254149.1004","url":null,"abstract":"Background: Considering the prevalence of this disease and the high mortality rate of gastric cancer in the country, it is necessary to investigate the causes and factors affecting this disease's incidence. Objective: This study aimed to analyze the structural equations of biological stress indices in patients with gastrointestinal cancer based on perceived stress mediated by rumination. Methods: This research was a descriptive-correlational study of structural equation modeling. The statistical population of this study included all patients with gastrointestinal cancer referred to Reza-Mashhad hospital and Avicenna Hospital in Tehran in 2020, of which 250 patients were selected by convenience sampling method. Data were collected using the perceived stress scale (PSS), Nolen and Hoxma rumination questionnaire, and biological stress indices. Data were analyzed using structural equation modeling and Pearson correlation statistical methods using SPSS.22 and AMOS.22 software. Results: The results showed that perceived stress (β=0.45, P0>0.001) directly affected rumination. Also, rumination (β=0.30, P=0.001) had a direct effect on biological stress indices. Rumination played a mediating role in the relationship between perceived stress and biological stress indices (RMSEA: 0.001; AGFI: 0.93). Conclusion: Considering that perceived stress and rumination are effective on biological stress of gastrointestinal patients, it is necessary for therapists to pay attention to modifying beliefs related to stress and rumination in the psychological health of gastrointestinal patients in order to improve the quality of life of patients.","PeriodicalId":20994,"journal":{"name":"Razavi International Journal of Medicine","volume":"8 1","pages":"8-13"},"PeriodicalIF":0.0,"publicationDate":"2020-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48937628","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Morphometric Characteristics of 1200 Normal Kidneys in Cadavers at the Mashhad Forensic Medicine Center 马什哈德法医中心1200具尸体正常肾脏的形态计量学特征
Razavi International Journal of Medicine Pub Date : 2018-10-01 DOI: 10.30483/RIJM.2018.34
M. Rezazadeh, M. Mohammadi, Maryam Sajjadian, Farhad Moghimian, S. Mohammadi, A. Hedjazi
{"title":"Morphometric Characteristics of 1200 Normal Kidneys in Cadavers at the Mashhad Forensic Medicine Center","authors":"M. Rezazadeh, M. Mohammadi, Maryam Sajjadian, Farhad Moghimian, S. Mohammadi, A. Hedjazi","doi":"10.30483/RIJM.2018.34","DOIUrl":"https://doi.org/10.30483/RIJM.2018.34","url":null,"abstract":"Background: Kidneys play an important role in excertion of bodily waste and the regulation of water and electrolyte. Currently available sources and books are based on anthropometric characteristics from Western countries. Determining national anthropometric measurements is a research priority in Iran. Based on a recent search, no study has been done on the standard data of kidneys in the Iranian population. Objectives: The present study investigated the morphometrical characteristics of the kidney (length, width, thickness, index, and weight) in an Iranian population. Methods: This cross-sectional study was performed on 604 cadavers (122 females/482 males) with a mean age of 43.86 ± 19.09 years in Mashhad Forensic Medicine Center in 2015. After approval of the Ethical Committee, demographic characterizes of cadavers were recorded. Then, length, width, thickness, index and weight of kidney were measured using a vernier caliber. At the end, data were analyzed using SPSS software. Results: Themean length of the kidney was 11.12 ± 1.73 cm, mean width was 5.09 ± 2.19 cm, mean thickness was 2.60 ± 1.39 cm, kidney index was 2.33 ± 1.62, and mean weight was 143.03 ± 52.97 g. No significant difference was seen in the morphometric values of the kidney between males and females (P>0.05), but a significant correlation was found between the age and body surface area of the cadavers and the length, width, thickness, index, and weight of the studied kidneys (P","PeriodicalId":20994,"journal":{"name":"Razavi International Journal of Medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46733848","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Identifying Pattern of Relationships between Attachment Styles, Life Satisfaction and Perfectionism in University Students 大学生依恋类型、生活满意度和完美主义关系的识别模式
Razavi International Journal of Medicine Pub Date : 2018-02-27 DOI: 10.5812/rijm.13060
Marjan Pouravari, M. Behboodi, Asghar Sharifi
{"title":"Identifying Pattern of Relationships between Attachment Styles, Life Satisfaction and Perfectionism in University Students","authors":"Marjan Pouravari, M. Behboodi, Asghar Sharifi","doi":"10.5812/rijm.13060","DOIUrl":"https://doi.org/10.5812/rijm.13060","url":null,"abstract":"Background: Life satisfaction is a subjective and unique concept to every human being which constitutes an essential component of subjective well-being. Objectives: The purpose of the present study was identifying the pattern of relationship between attachment styles, life satisfaction and perfectionism in university students. Methods: The statistical society included all students of Azad university of Roodehen who were studying at this university in 2014 15 academic year. The sample size was 271 undergraduate students who were selected by stratification random sampling from all faculties except faculty of education and counseling and also Psychology. The data were collected using life satisfaction scale, collins and reid’s adult attachment styles and terry and short’s positive and negative perfectionism scale. Results: The findings showed that positive and negative perfectionism variables influence on explanation of life satisfaction changes. Anxious attachment through negative perfectionism influences directly and indirectly on explanation of life satisfaction changes. Also avoidant attachment through positive and negative perfectionism influences directly and indirectly on explanation of life satisfaction changes. However, secure attachment neither directly nor indirectly influences on explanation of life satisfaction changes. Conclusions: The results of this study have several important implications for counselors who work with perfectionism. Counselors should consider perfectionism as a multidimensional construct with both healthy and unhealthy dimensions rather than as only problematic construct.","PeriodicalId":20994,"journal":{"name":"Razavi International Journal of Medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47008228","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Investigation of Self-Esteem in High School Students with Premenstrual Syndrome 高中月经前期综合征学生自尊状况调查
Razavi International Journal of Medicine Pub Date : 2018-02-24 DOI: 10.5812/RIJM.12249
F. Ghodrati, M. Dehghani, P. Tavakoli, M. Akbarzadeh
{"title":"Investigation of Self-Esteem in High School Students with Premenstrual Syndrome","authors":"F. Ghodrati, M. Dehghani, P. Tavakoli, M. Akbarzadeh","doi":"10.5812/RIJM.12249","DOIUrl":"https://doi.org/10.5812/RIJM.12249","url":null,"abstract":"Background: Premenstrual syndrome (PMS) is one of the most common disorders of reproductive age, and it is reported that 90% 85% of the people are suffering from this disorder. Among the multiple symptoms of mental premenstrual syndrome, dysphoria, irritability, tension, anxiety and physical symptoms of bloating and breast pain are more common symptoms that can interfere with personal, family and community relationships. Objectives: This study aimed to evaluate the frequency of the symptoms of PMS (physical, psychological and social) and the level of self-esteem in girls with PMS in 2013. Methods: A cross-sectional study was performed on 200 girl high-school students of Shiraz city who had PMS. The study tools included demographic questionnaire, premenstrual symptoms, screening tool (PSST), (completed in two consecutive months) and Cooper Smith questionnaire. Data was analyzed by applying SPSS (version 16) and descriptive statistics. Results: The mean age of the study population was 16.34 ± 1.06. About 50.5 percent were within 14-16 years old. 11.43 ± 3.89, 12.87 ± 4.49, and 39.28 ± 16.2 were the mean scores of physical, mental and total symptoms in girls with PMS, respectively. Moderate and high levels of self-esteem were reported 53% and 47% respectively among the patients with PMS. Conclusions: The results showed that high self-esteem is decreased in patients with premenstrual syndrome. Due to the mood disorders, the subjects may avoid their perfection tendency and intensify their negative self-concept leading to low self-esteem. Different treatments, particularly psychological remedies, are required for those suffering from PMS.","PeriodicalId":20994,"journal":{"name":"Razavi International Journal of Medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48111694","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Health Literacy and Health Inequity in the Community Medicine Specialists Point of View 社区医学专家的健康素养与健康不公平
Razavi International Journal of Medicine Pub Date : 2018-02-12 DOI: 10.5812/RIJM.58404
M. Dadgarmoghaddam, S. Niroumand
{"title":"Health Literacy and Health Inequity in the Community Medicine Specialists Point of View","authors":"M. Dadgarmoghaddam, S. Niroumand","doi":"10.5812/RIJM.58404","DOIUrl":"https://doi.org/10.5812/RIJM.58404","url":null,"abstract":"Health Literacy and Health Inequity in the Community Medicine Specialists Point of View Maliheh Dadgarmoghaddam, and Shabnam Niroumand Assistant Professor of Community Medicine, Departments of Community Medicine, Faculty of Medicine, Mashhad University of Medical Science, Mashhad, IR Iran Assistant Professor of Community Medicine, Department of Educational Development, Faculty of Medicine, Mashhad University of Medical Science, Mashhad, IR Iran Corresponding author: Shabnam Niroumand, Assistant Professor of Community Medicine, Department of educational Development, Faculty of Medicine, Mashhad University of Medical Science, Mashhad, IR Iran. Tel: +98-9153036693, Fax: +98-3882860, E-mail: shabnamniroomand@yahoo.com","PeriodicalId":20994,"journal":{"name":"Razavi International Journal of Medicine","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43294671","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Assessment the of Amplification HER-2/neu Gene by Chromogenic In Situ Hybridization (CISH) Compared to Immunohistochemistry (IHC) Method in Gastric Cancer 显色原位杂交(CISH)与免疫组化(IHC)方法扩增癌症HER-2/neu基因的比较
Razavi International Journal of Medicine Pub Date : 2018-02-10 DOI: 10.5812/RIJM.13397
S. Amoueian, A. Attaranzadeh, Mahdi Montazer, Arash Akhavan Rezayat, Amir Behforouz, Fatemeh Sobhani
{"title":"Assessment the of Amplification HER-2/neu Gene by Chromogenic In Situ Hybridization (CISH) Compared to Immunohistochemistry (IHC) Method in Gastric Cancer","authors":"S. Amoueian, A. Attaranzadeh, Mahdi Montazer, Arash Akhavan Rezayat, Amir Behforouz, Fatemeh Sobhani","doi":"10.5812/RIJM.13397","DOIUrl":"https://doi.org/10.5812/RIJM.13397","url":null,"abstract":"Background: Gastric cancer has a high mortality rate and often has a poor treatment outcome. The HER2/neu gene target therapy has been known as a potential way for treatment. Objectives: The goal of our study was assessment the relation between chromogenic in situ hybridization (CISH) and immunohistochemistry (IHC) methods in determining the best diagnostic method for gastric cancer. Methods: In this historical cohort study, 50 gastric cancer samples were analyzed by CISH and IHC. The relation between clinical-pathological parameters of HER2/neu was also analyzed. Alive patients were followed from 2009 through 2012 for the main out-comes (mortality). The results of these two methods, in terms of sex, age, tumor size, grading, staging, tumor location, metaplasia, presence of necrosis and ulceration, vascular invasion, the TNM system, mucin or signet producing adenocarcinoma cells and patient survival rates were compared. Results: There was no significant difference between IHC and CISH regarding the sex, age, tumor size, grading, staging, tumor location, metaplasia, presence of necrosis and ulceration, vascular invasion, the TNM system, mucin or signet producing adenocarci-nomacellsandpatientsurvivalrates. Comparisonof TNMscoresbythesetwomethodsshowednosignificantrelationshipbetween IHC and staging, but a statistically significant difference between CISH and different N staging, (P < 0.05) was assessed. Conclusions: Comparison between IHC and CISH showed the only significant relationship between CISH and different N staging. Therefore, low amplified CISH was a better diagnostic method for gastric cancer, compared to low expression in IHC.","PeriodicalId":20994,"journal":{"name":"Razavi International Journal of Medicine","volume":"6 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41467879","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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