Reproductive and Developmental Medicine最新文献

{"title":"Stromal cell decidualization and embryo implantation - A vulnerable step leading to successful pregnancy","authors":"Luhan Jiang, S. Fernando, S. Kodithuwakku, Dandan Cao, W. Yeung, Kai-Fai Lee","doi":"10.1097/rd9.0000000000000076","DOIUrl":"https://doi.org/10.1097/rd9.0000000000000076","url":null,"abstract":"","PeriodicalId":20959,"journal":{"name":"Reproductive and Developmental Medicine","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2023-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"61786348","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between LH level decrease on the triggering day and pregnancy outcome for IVF/ICSI patients following GnRH antagonist protocol: a retrospective cohort study","authors":"Qing-fang Li, Min-Yue Tang, Gui-Quan Wang, Xijun Chen, Guo-fang Feng, Yimei Zhu","doi":"10.1097/rd9.0000000000000071","DOIUrl":"https://doi.org/10.1097/rd9.0000000000000071","url":null,"abstract":"","PeriodicalId":20959,"journal":{"name":"Reproductive and Developmental Medicine","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2023-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47818046","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Role of MicroRNAs in Embryo–Endometrial Interactions: Biological Functions and Clinical Applications","authors":"S. Qi, S. Kodithuwakku, R. T. Pang, P. Chiu, Mary Y. Tang, Kai-Fai Lee","doi":"10.1097/rd9.0000000000000073","DOIUrl":"https://doi.org/10.1097/rd9.0000000000000073","url":null,"abstract":"","PeriodicalId":20959,"journal":{"name":"Reproductive and Developmental Medicine","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2023-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43905743","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Factors influencing the accuracy of sonography-estimated fetal weight: a retrospective cohort study in the Chinese population","authors":"Fangcan Sun, Hai-hong Wang, Jing-jing Zhang, X. Gu, T. Hu, Ming-yue Wang, Yinqi Zhu, You-Guo Chen, Bingsha Han","doi":"10.1097/rd9.0000000000000072","DOIUrl":"https://doi.org/10.1097/rd9.0000000000000072","url":null,"abstract":"","PeriodicalId":20959,"journal":{"name":"Reproductive and Developmental Medicine","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2023-06-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44729307","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Peripheral blood transcriptome analysis of patients with ovarian hyperstimulation syndrome through high-throughput sequencing.","authors":"Bo Yan,&nbsp;Bin Wu,&nbsp;Zhi-Qiang Wang,&nbsp;Yan Wei,&nbsp;Ya-Li Ni","doi":"10.1097/RD9.0000000000000058","DOIUrl":"https://doi.org/10.1097/RD9.0000000000000058","url":null,"abstract":"<p><p>Ovarian hyperstimulation syndrome (OHSS) is a frequent iatrogenic complication that arises during assisted reproduction and accounts for approximately 30% of all <i>in vitro</i> fertilization cycles. Using high-throughput sequencing, we investigated the peripheral blood transcriptome of patients with OHSS.</p><p><strong>Methods: </strong>Peripheral blood samples were obtained from 15 patients in each of the OHSS high-risk and low-risk groups on the ovum pick-up day. Subsequently, high-throughput sequencing was used to obtain the peripheral blood transcriptomes of five patients each from the high- and low-risk groups. Bioinformatic tools were used for mRNA expression profile mapping and screening of differentially expressed genes (DEGs). Bioinformatics techniques were also implemented in the Kyoto Encyclopedia of Genes Genomes (KEGG) signal pathway, Gene Ontology (GO) function, and protein-protein interaction (PPI) network analyses of DEGs.</p><p><strong>Results: </strong>A total of 20,031 genes were identified and 148 were found to be differentially expressed (<i>P <</i>0.05, |log₂FC| > 0.58), with 52 upregulated and 96 downregulated genes. GO and KEGG analyses indicated that these genes were involved in extracellular corpuscles (GO: 0070062), plasma membrane (GO: 0005886), extracellular regions (GO: 0005576), immune system response (GO: 0006955), PI3K-Akt signaling pathways (hsa04151), cell adhesion molecules (CAMs, hsa04514), focal adhesion (hsa04510), and complement and coagulation cascades (hsa04610). The PPI network and realtime fluorescence quantitative polymerase chain reaction (qPCR) verification predicted that complement C3, von Willebrand factor, and vascular cell adhesion protein 1 proteins are highly implicated in OHSS and may serve as potential biomarkers for future OHSS studies.</p><p><strong>Conclusion: </strong>Transcriptome analysis revealed several DEGs related to OHSS risk factors in the peripheral blood, indicating that these DEGs may be novel players in OHSS development.</p>","PeriodicalId":20959,"journal":{"name":"Reproductive and Developmental Medicine","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/7f/33/rd9-7-115.PMC10241322.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9911495","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Characterization of folic acid, 5-methyltetrahydrofolate and synthetic folinic acid in the high-affinity folate transporters: impact on pregnancy and development.","authors":"Ana M Palacios,&nbsp;Rachel A Feiner,&nbsp;Robert M Cabrera","doi":"10.1097/RD9.0000000000000034","DOIUrl":"https://doi.org/10.1097/RD9.0000000000000034","url":null,"abstract":"<p><p>Folates are B vitamins that are essential for several molecular, cellular, and biological processes, including nucleotide synthesis, methylation, and methionine cycling. The physiological impacts of these processes on health also extend to cell proliferation, folate deficiency anemia, and reduction of the risk of birth defects during pregnancy. The primary objective of this study was to characterize the binding affinities of different folate forms, folic acid (FA), 5-methyltetrahydrofolate (5MTHF), and folinic acid, to the folate receptors α and β, and to the bovine milk folate binding protein. These three dietary forms of folate are found in enriched grains (FA), various fruits and leafy vegetables (folinic acid), and red blood cells (5MTHF).</p><p><strong>Methods: </strong>The half maximal inhibitory concentration values and binding curves of each of these folates for each receptor were determined.</p><p><strong>Results: </strong>Our results indicated that FA had the highest affinity for all folate receptors, followed by 5MTHF, and lastly, by folinic acid, examined by several orders of magnitudes.</p><p><strong>Conclusion: </strong>These data are expected to provide new insights into the therapeutic applications of the different forms of folate in a variety of diseases.</p>","PeriodicalId":20959,"journal":{"name":"Reproductive and Developmental Medicine","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/40/90/rd9-7-102.PMC10259187.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9633098","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of changing the COS protocol in patients without a transplantable embryo in the previous IVF/ICSI cycle","authors":"Shan Yi, Yi-Hua Yang, Yin Bi, Zhonghong Zeng, Xi Wang, Mu-Jun Li, Wenwen Ma","doi":"10.1097/rd9.0000000000000070","DOIUrl":"https://doi.org/10.1097/rd9.0000000000000070","url":null,"abstract":"","PeriodicalId":20959,"journal":{"name":"Reproductive and Developmental Medicine","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2023-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48527515","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Simplified lung ultrasound method to predict the respiratory support needs of neonates whose mothers had pregnancy complications: a diagnostic accuracy study","authors":"Xin-Ao Lin, Xuefeng Wang, Xiao-Bo Fan, G. Xi, Ji-mei Wang","doi":"10.1097/RD9.0000000000000069","DOIUrl":"https://doi.org/10.1097/RD9.0000000000000069","url":null,"abstract":"Objective: Some pregnancy complications are associated with respiratory problems in infants. Early identification and implementation of respiratory support are needed for these infants. This study aimed to (1) use lung ultrasound (LU) for predicting the respiratory support requirements of infants and (2) simplify the examination method to facilitate its clinical application. Methods: Neonates underwent LU examinations within 1 hour of birth. The infants were divided into a pregnancy complication (PC) group and a control group according to their mothers’ clinical data. The primary outcome measure was the need for respiratory support. Predictive models were established based on the differences in LU patterns between the two groups. The predictive value of the models was compared with that of the LU score (LUS) system, which has been widely used in other studies. Simplified models were established by analyzing the predictive effects of LU patterns in different parts of the lungs. Predictive reliability was tested using the receiver operating characteristic curve analysis. Results: PC and control groups had 29 and 117 neonates, respectively; a total of 22 neonates required respiratory support. The PC and control groups showed differences in respiratory support requirements, A-lines, and coalesced B-lines. The percentages of A-lines and coalesced B-lines were associated with respiratory support requirements. The optimal cutoff values for the percentages of the A-lines and coalesced B-lines were 55.7% and 24.5%, respectively. Similar effects were obtained by calculating the percentage of coalesced B-lines in four areas (R3, R4, L3, and L4). These methods were judged as more visual and convenient than LUS assessment. Conclusion: The percentages of A-line and coalesced B-lines on LU images can be used to predict the respiratory support needs of neonates whose mothers had pregnancy complications. Only four areas (R3, R4, L3, and L4) had similar predictive values.","PeriodicalId":20959,"journal":{"name":"Reproductive and Developmental Medicine","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2023-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42746949","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A novel tube for sperm density gradient centrifugation procedure","authors":"Yun-jing Xue, W. Du, Cunzhong Deng, Yuan Xu, Chen Liu, Yan-Nan Yang, Ling Wang, Yu-Zhen Lv, Zheng Li, R. Chian","doi":"10.1097/rd9.0000000000000068","DOIUrl":"https://doi.org/10.1097/rd9.0000000000000068","url":null,"abstract":"","PeriodicalId":20959,"journal":{"name":"Reproductive and Developmental Medicine","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2023-05-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41381787","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Macrosomia is associated with overweight in childhood: a follow-back of a cohort established in the early years of the obesity epidemic","authors":"Temitayo M Adebile, Amarachukwu F. Orji, F. Twum, Jian Zhang","doi":"10.1097/rd9.0000000000000067","DOIUrl":"https://doi.org/10.1097/rd9.0000000000000067","url":null,"abstract":"","PeriodicalId":20959,"journal":{"name":"Reproductive and Developmental Medicine","volume":null,"pages":null},"PeriodicalIF":0.8,"publicationDate":"2023-05-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"61786338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}