Research Journal of Pharmacology and Pharmacodynamics最新文献_第8页

Review on Curcuma aromatic as an Herbal medicine 姜黄作为一种草药的研究进展

Research Journal of Pharmacology and Pharmacodynamics Pub Date : 2022-04-29 DOI: 10.52711/2321-5836.2022.00016

Sangita P. Shirsat, Kaveri P. Tambe, Gayatri D. Patil, Ganesh G. Dhakad

{"title":"Review on Curcuma aromatic as an Herbal medicine","authors":"Sangita P. Shirsat, Kaveri P. Tambe, Gayatri D. Patil, Ganesh G. Dhakad","doi":"10.52711/2321-5836.2022.00016","DOIUrl":"https://doi.org/10.52711/2321-5836.2022.00016","url":null,"abstract":"Curcuma aromatica is also a familiar Chinese herb used for treating diseases with blood stasis and has been consider as an effective anticancer herb. The rhizomes of Curcuma aromatic are used in original medicine for exterior applications on skin diseases, sprain, bruise, in snake poison, holdup the ageing process, pain relief, protecting against liver diseases and also to enhance complexion. The constituents identified in the oil is alpha-pinene, beta-pinene, camphene, 1,8-cineol, isofurano-germacrene, borneol, isoborneol, beta-curcumene, ar-curcumene, xanthorrhizol, germacrone, camphor, and curzerenone and the constituent in oil was found to differ from place to place. Bioactive compounds, counting 1, 8-cineole, ar-curcumene, ar-turmerone, β-elemene, camphor, curcumol, curdione, germacrone, linalool, xanthorrhizol, and zingiberene, from the essential oil of C. aromatica have been verified to possess anticancer properties. Usually used as an anti- inflammatory agent. It possesses a wide range of activities like Anti –inflammatory, anti-tumor, immunological effects, wound healing, anti -fungal, anti -oxidant, anti - microbial, anti-diabetic, anti-platelet and mosquito repellent activity of wild turmeric. The use of analgesic drugs, such as opiates and NSAIDs, for pain relief has been stagnated as these drugs are reported to have adverse side effects, including addiction and gastrointestinal disorders.","PeriodicalId":20945,"journal":{"name":"Research Journal of Pharmacology and Pharmacodynamics","volume":"10 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87416857","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Review of Novel Corona Virus Disease (Covid-19) in India 印度新型冠状病毒病(Covid-19)研究进展

Research Journal of Pharmacology and Pharmacodynamics Pub Date : 2022-04-29 DOI: 10.52711/2321-5836.2022.00018

Ghanshyam Sevak, Yashpal Singh Chauhan, Narendra B. Parihar, Mahendra Singh Rathore

{"title":"Review of Novel Corona Virus Disease (Covid-19) in India","authors":"Ghanshyam Sevak, Yashpal Singh Chauhan, Narendra B. Parihar, Mahendra Singh Rathore","doi":"10.52711/2321-5836.2022.00018","DOIUrl":"https://doi.org/10.52711/2321-5836.2022.00018","url":null,"abstract":"Novel coronavirus also known as severe acute respiratory syndrome Coronavirus 2 (SARS-CoV-2) was emerged from Wuhan, China and have taken catastrophic form globally. India being a dense populated country is also affected by it’s deadly infection. Bats were considered as its primary host but COVID-19 disease became pandemic via human to human transmission by droplet nuclei. The incubation period ranges upto 14 days and main symptoms of disease were noticed as atypical pneumonia, fever, difficult breathing, decreased SPO2 level and ultimately death due to respiratory failure depending upon immune status of the patients. Coronaviruses are positive-sense, single-stranded RNA viruses and harbour a genome (30 kb) consisting of two terminal untranslated regions and twelve putative functional open reading frames (ORFs), encoding for non-structural and structural proteins. There are sixteen putative non-structural proteins, including proteases, RNA-dependent RNA polymerase, helicase, other proteins involved in the transcription and replication of SARS-CoV-2, and four structural proteins, including spike protein (S), envelope (E), membrane (M), and nucleocapsid (N). SARS-CoV-2 infection, with a heavy viral load in the body, destroys the human lungs through cytokine storm, especially in elderly persons and people with immunosuppressed disorders. A number of drugs have been repurposed and employed, but still, no specific antiviral medicine has been approved by the FDA to treat this disease. This review provides a current status of the COVID-19, epidemiology, an overview of phylogeny, mode of action, diagnosis, and possible treatment methods and vaccines.","PeriodicalId":20945,"journal":{"name":"Research Journal of Pharmacology and Pharmacodynamics","volume":"13 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82370484","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Journey of Chloroquine/ Hydroxychloroquine in the management of COVID-19 氯喹/羟氯喹治疗COVID-19的历程

Research Journal of Pharmacology and Pharmacodynamics Pub Date : 2022-04-29 DOI: 10.52711/2321-5836.2022.00019

K. Sekhri, S. Bhanwra, R. Nandha, S. Aditya, Deepak Bhasin

{"title":"Journey of Chloroquine/ Hydroxychloroquine in the management of COVID-19","authors":"K. Sekhri, S. Bhanwra, R. Nandha, S. Aditya, Deepak Bhasin","doi":"10.52711/2321-5836.2022.00019","DOIUrl":"https://doi.org/10.52711/2321-5836.2022.00019","url":null,"abstract":"Chloroquine was discovered in 1934 and since then it is used as an antimalarial drug saving millions of lives. Chloroquine and its analogue Hydroxychloroquine possess pleotropic pharmacological actions and are of proven value in multiple conditions ranging from protozoal to autoimmune diseases. Advantage with these drugs is their well-documented tolerability profile. In Severe Acute Respiratory Syndrome Corona virus-2 (SARS-CoV-2), these drugs in vitro showed promising results working at multiple sites ranging from prevention of entry of the virus into human cells, halting the multiplication by altering the pH of internal organelles towards basic side and via exocytosis. These drugs also act as immunomodulators to prevent flare up of cytokines and interleukin cascade, thus preventing multiple organ dysfunction syndrome. In this review we trend the journey of these drugs, how high hopes were pinned to their use but they failed to show any mortality benefit in hospitalized patients. However, still certain studies are underway to explore their role in prophylaxis or otherwise. Medline, Medscape, EMBASE, Cochrane database, Scopus and clinicaltrials.gov were searched using terms like “SARS-CoV-2”, “COVID-19”, “Chloroquine” and “Hydroxychloroquine”.","PeriodicalId":20945,"journal":{"name":"Research Journal of Pharmacology and Pharmacodynamics","volume":"56 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79078946","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Zika Virus and its Pathogenesis and its Treatment 寨卡病毒及其发病机制和治疗

Research Journal of Pharmacology and Pharmacodynamics Pub Date : 2022-04-29 DOI: 10.52711/2321-5836.2022.00013

Gaikwad Adarsh, Patil Rutuja

引用次数: 0

The Various Pharmacological Activity of Adansonia digitata 牡丹的各种药理活性

Research Journal of Pharmacology and Pharmacodynamics Pub Date : 2022-03-05 DOI: 10.52711/2321-5836.2022.00009

Harshit Rana, R. Kumar, Aarti Chopra, Sweta Pundir, Girendra Kumar Gautam, Gautam Kumar

引用次数: 2

A Review on Importance of Artificial Intelligence in Alzheimer’s Disease and it’s Future Outcomes for Alzheimer’s Disease 人工智能在阿尔茨海默病中的重要性及其对阿尔茨海默病的未来治疗效果综述

Research Journal of Pharmacology and Pharmacodynamics Pub Date : 2022-03-05 DOI: 10.52711/2321-5836.2022.00003

P. Minesh

引用次数: 3

Thyroid Disorder: An Overview 甲状腺疾病:综述

Research Journal of Pharmacology and Pharmacodynamics Pub Date : 2022-03-05 DOI: 10.52711/2321-5836.2022.00007

S. D. Mankar, S. Bhawar, Mohini R. Shelke, Pankaj Sonawane, Shraddha Parjane

{"title":"Thyroid Disorder: An Overview","authors":"S. D. Mankar, S. Bhawar, Mohini R. Shelke, Pankaj Sonawane, Shraddha Parjane","doi":"10.52711/2321-5836.2022.00007","DOIUrl":"https://doi.org/10.52711/2321-5836.2022.00007","url":null,"abstract":"The Asteraceae family's chamomile (Matricaria chamomilla L.) may be a well-known medicinal plant. Chamaemelum nobile, also referred to as Roman chamomile, is usually referred to as real chamomile or sweet false chamomile. Effect of sweet false chamomile extract on linearincisional wound healing was studied. The article briefly review on the medicinal and cosmetic benefits of matricaria. The major medicinal uses of this plant is antiinflammatory, antidiarrheal, antacid. chamoline as an cosmetic ingredient is good for skin and hair. Mouthwashes and tooth pase also contain chamomile as an ingredient. Chamomile also have antioxidant property. It treat gastrointestinal problem by acting as purgative and also use to treat acidity. It promotes wound healing effect in the case of cradle and bunions. The flavonoids apigenin, luteolin, quercetin, patuletin, and volatile oil compounds like bisabolol and its oxides, also as azulenes, are liable for chamomile's biological action. There are several chamomile chemocultivars. Chamomile is anti-inflammatory, deodorant, antibacterial, carminative, sedative, antiseptic, anticatarrhal, and spasmolytic.","PeriodicalId":20945,"journal":{"name":"Research Journal of Pharmacology and Pharmacodynamics","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87236552","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Review on Radiation Therapy on Cancer 癌症放射治疗研究进展

Research Journal of Pharmacology and Pharmacodynamics Pub Date : 2022-03-05 DOI: 10.52711/2321-5836.2022.00002

Ganesh G. Dhakad, G. D. Patil, Ashwini C. Nikum, Sangita P. Shirsat

引用次数: 1

Role of Spices and Herbs in Controlling Dental Problems 香料和草药在控制牙齿问题中的作用

Research Journal of Pharmacology and Pharmacodynamics Pub Date : 2022-03-05 DOI: 10.52711/2321-5836.2022.00004

S. Shankar, G. P, Roja E.

{"title":"Role of Spices and Herbs in Controlling Dental Problems","authors":"S. Shankar, G. P, Roja E.","doi":"10.52711/2321-5836.2022.00004","DOIUrl":"https://doi.org/10.52711/2321-5836.2022.00004","url":null,"abstract":"Herbs and spices are not just useful to us as flavouring agents but they are actually nature's way to treat dental infections also. Several dental problems like tooth ache, caries, etc have become very common among the human population across the globe. These are mainly due to the action of microorganisms like Streptococcus mutans, Streptococcus sobrinus, lactobacilli, etc. Such problems can actually be cured naturally by using herbs and spices like cloves, thyme, peppermint leaves, goldenseal, green tea, etc which contain particular substances (that are found in dental medicines), which act against the microorganisms causing dental problems by either killing them or inhibiting their growth, are used to treat these problems. Apart from the above use, it is also effective in cases of infections where allopathic medications have no or minimal actions which may be due to the increased resistance exhibited by the pathogens to particular allopathic medications, some antibacterial agents currently used in dentistry produces adverse-affects like nausea, vomiting, diarrhoea, headache, staining of teeth, etc. and financial considerations in relation to allopathic medications in developing countries creates a need for alternative prevention and treatment options that are safe, effective and economical. Hence, the search for alternative products continues and herbs and spices that were used as traditional medicines in the ancient times are considered as good alternatives. Therefore, understanding the role of herbs and spices in controlling dental infection scan help people to cure and prevent these infections in a natural way and help them overcome all the above problems.","PeriodicalId":20945,"journal":{"name":"Research Journal of Pharmacology and Pharmacodynamics","volume":"56 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75162626","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

A Brief Review on Ophthalmic Suspension for Covid-19 Infection 新型冠状病毒感染的眼悬液研究综述

Research Journal of Pharmacology and Pharmacodynamics Pub Date : 2022-03-05 DOI: 10.52711/2321-5836.2022.00005

G. Sahu, A. Chandy, Raju Sahu

引用次数: 0