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First manic episode in a 55-year-old man after initiation of aripiprazole. 55岁男性服用阿立哌唑后首次躁狂发作。
Psychiatry (Edgmont (Pa. : Township)) Pub Date : 2010-04-01
Andrew Donohue
{"title":"First manic episode in a 55-year-old man after initiation of aripiprazole.","authors":"Andrew Donohue","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Aripiprazole is a novel antipsychotic medication that is used to treat a number of psychiatric conditions, including schizophrenia, bipolar disorder, and major depressive disorder. Although not specifically indicated for this, novel antipsychotics including aripiprazole are also used for treatment of obsessive compulsive disorder. The following case involves a 55-year-old man with refractory obsessive compulsive disorder who developed his first manic episode after taking aripiprazole. The author reviews other cases of aripiprazole-induced mania and discusses the possible pharmacodynamic mechanisms of this reaction.</p>","PeriodicalId":20822,"journal":{"name":"Psychiatry (Edgmont (Pa. : Township))","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2010-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2877620/pdf/PE_7_4_37.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"29024050","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Real-World Data on: Attention Deficit Hyperactivity Disorder Medication Side Effects. 真实世界数据:注意缺陷多动障碍药物副作用。
Psychiatry (Edgmont (Pa. : Township)) Pub Date : 2010-04-01
Elisa Cascade, Amir H Kalali, Sharon B Wigal
{"title":"Real-World Data on: Attention Deficit Hyperactivity Disorder Medication Side Effects.","authors":"Elisa Cascade,&nbsp;Amir H Kalali,&nbsp;Sharon B Wigal","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In this article, we provide information on patient-reported side effects from a cross-section of real-world patients. Specifically, data on side effects were tabulated for patients taking one of the following attention deficit hyperactivity disorder medications: amphetamine and dextroamphetamine; atomoxetine; dexmethylphenidate; isdexamfetamine; and methylphenidate. Forty-eight percent of the approximately 325 patients surveyed reported having experienced a side effect as a result of taking an attention deficit hyperactivity disorder medication. Most common side effects mentioned included loss of appetite, sleep problems, and mood disturbances. Only 21 percent of side effects were considered very bothersome or extremely bothersome. Regardless of how bothersome the side effects were, only 20 percent of patients mentioned the side effects to their prescribing physicians.</p>","PeriodicalId":20822,"journal":{"name":"Psychiatry (Edgmont (Pa. : Township))","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2010-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2877616/pdf/PE_7_4_13.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"29024046","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Accurately diagnosing and treating borderline personality disorder: a psychotherapeutic case. 准确诊断和治疗边缘型人格障碍:一个心理治疗案例。
Psychiatry (Edgmont (Pa. : Township)) Pub Date : 2010-04-01
Ashley B Johnson, Julie P Gentile, Terry L Correll
{"title":"Accurately diagnosing and treating borderline personality disorder: a psychotherapeutic case.","authors":"Ashley B Johnson,&nbsp;Julie P Gentile,&nbsp;Terry L Correll","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The high prevalence of comorbid bipolar and borderline personality disorders and some diagnostic criteria similar to both conditions present both diagnostic and therapeutic challenges. This article delineates certain symptoms which, by careful history taking, may be attributed more closely to one of these two disorders. Making the correct primary diagnosis along with comorbid psychiatric conditions and choosing the appropriate type of psychotherapy and pharmacotherapy are critical steps to a patient's recovery. In this article, we will use a case example to illustrate some of the challenges the psychiatrist may face in diagnosing and treating borderline personality disorder. In addition, we will explore treatment strategies, including various types of therapy modalities and medication classes, which may prove effective in stabilizing or reducing a broad range of symptomotology associated with borderline personality disorder.</p>","PeriodicalId":20822,"journal":{"name":"Psychiatry (Edgmont (Pa. : Township))","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2010-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2877618/pdf/PE_7_4_21.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"29024048","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cranial Nerve VIII: Hearing and Vestibular Functions. 颅神经VIII:听觉和前庭功能。
Psychiatry (Edgmont (Pa. : Township)) Pub Date : 2010-03-01
Richard D Sanders, Paulette Marie Gillig
{"title":"Cranial Nerve VIII: Hearing and Vestibular Functions.","authors":"Richard D Sanders,&nbsp;Paulette Marie Gillig","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Cranial nerve VIII brings sound and information about one's position and movement in space into the brain. The auditory and vestibular systems subserve several functions basic to clinical medicine and to psychiatry. This article covers the basics of cranial nerve VIII, hearing and vestibular systems, including common problems with hearing and balance, problems with hearing and balance that tend to be found in psychiatric patients, and some simple assessments of value in clinical practice.</p>","PeriodicalId":20822,"journal":{"name":"Psychiatry (Edgmont (Pa. : Township))","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2010-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2861521/pdf/PE_7_3_17.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"28958873","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
48,XXYY in a General Adult Psychiatry Department. XXYY在普通成人精神科。
Psychiatry (Edgmont (Pa. : Township)) Pub Date : 2010-03-01
Nuno Borja-Santos, Bruno Trancas, Pilar Santos Pinto, Bárbara Lopes, António Gamito, Sandra Almeida, Berta Ferreira, Antonio Luengo, Carlos Vieira, Jorge Martinho, Bruno Pereira, Graça Cardoso
{"title":"48,XXYY in a General Adult Psychiatry Department.","authors":"Nuno Borja-Santos,&nbsp;Bruno Trancas,&nbsp;Pilar Santos Pinto,&nbsp;Bárbara Lopes,&nbsp;António Gamito,&nbsp;Sandra Almeida,&nbsp;Berta Ferreira,&nbsp;Antonio Luengo,&nbsp;Carlos Vieira,&nbsp;Jorge Martinho,&nbsp;Bruno Pereira,&nbsp;Graça Cardoso","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The 48,XXYY syndrome is a distinct clinical and genetic entity, with an incidence of 1:17,000 to 1:50,000 newborns. Patients often access mental healthcare services due to behavior problems, such as aggressiveness and impulsiveness, and are frequently intellectually disabled. We report a case of a patient with 48,XXYY syndrome treated in a general adult psychiatry department.A 23-year-old man was frequently admitted to our inpatient psychiatric unit (14 admissions in five years) due to disruptive behavior, including self harm, aggression to objects and animals, and fire-setting behavior, in a context of dysphoric mood and marked impulsivity. Upon observation, the patient had mild intellectual disability, with prominent impulsive and aggressive features and very low tolerance to frustration. His physical examination revealed hypertelorism, increased thickness of neck, acne, sparse body hair, triangular pubic hair distribution, fifth digit clinodactyly, small testicles and penis, and gynecoid pelvis. Laboratory analysis revealed endocrine abnormalities (low plasma testosterone and subclinical hypothyroidism). Cardiac Doppler sonogram was normal. Electroencephalogram revealed only a diffuse slowing electrogenesis, with no etiological specificity. Clinical suspicion of a chromosomal disorder was confirmed by a 48,XXYY karyotype. Subsequent magnetic resonance imaging detected discrete bilateral reduction of the hippocampal formations, possibly related to temporal dysgenesia. Psychopharmacological treatment options met moderate success, with lack of adherence. Other psychosocial treatment interventions ensued, including family therapy and psychoeducation. We underscore the need to be alert for chromosomal disorders, even in a general adult psychiatry department, as a minority of patients may reach adult care without proper diagnosis.</p>","PeriodicalId":20822,"journal":{"name":"Psychiatry (Edgmont (Pa. : Township))","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2010-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2861523/pdf/PE_7_3_32.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"28958875","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Selective mutism: a review of etiology, comorbidities, and treatment. 选择性缄默症:病因、合并症和治疗的综述。
Psychiatry (Edgmont (Pa. : Township)) Pub Date : 2010-03-01
Priscilla Wong
{"title":"Selective mutism: a review of etiology, comorbidities, and treatment.","authors":"Priscilla Wong","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Selective mutism is a rare and multidimensional childhood disorder that typically affects children entering school age. It is characterized by the persistent failure to speak in select social settings despite possessing the ability to speak and speak comfortably in more familiar settings. Many theories attempt to explain the etiology of selective mutism.Comorbidities and treatment. Selective mutism can present a variety of comorbidities including enuresis, encopresis, obsessive-compulsive disorder, depression, premorbid speech and language abnormalities, developmental delay, and Asperger's disorders. The specific manifestations and severity of these comorbidities vary based on the individual. Given the multidimensional manifestations of selective mutism, treatment options are similarly diverse. They include individual behavioral therapy, family therapy, and psychotherapy with antidepressants and anti-anxiety medications.Future directions. While studies have helped to elucidate the phenomenology of selective mutism, limitations and gaps in knowledge still persist. In particular, the literature on selective mutism consists primarily of small sample populations and case reports. Future research aims to develop an increasingly integrated, multidimensional framework for evaluating and treating children with selective mutism.</p>","PeriodicalId":20822,"journal":{"name":"Psychiatry (Edgmont (Pa. : Township))","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2010-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2861522/pdf/PE_7_3_23.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"28958874","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Personality dysfunction and employment dysfunction: double, double, toil and trouble. 人格功能障碍和就业功能障碍：双重、双重、辛苦和麻烦。
Psychiatry (Edgmont (Pa. : Township)) Pub Date : 2010-03-01
Randy A Sansone, Lori A Sansone
{"title":"Personality dysfunction and employment dysfunction: double, double, toil and trouble.","authors":"Randy A Sansone, Lori A Sansone","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>According to the Diagnostic and Statistical Manual of Mental Disorders, personality disorders are characterized by functional impairment, which may unfold in the work environment. A number of empirical studies convincingly suggest that the presence of personality dysfunction has substantial negative and diffuse effects on work functioning. However, not all studies are in agreement. In addition, there may be specific mediating variables that modulate the likelihood that an individual with a personality disorder will experience work difficulties. These include the type of personality disorder, degree of neuroticism and disagreeableness, extent of social dysfunction, and severity of symptoms-all of which appear to be interrelated. Because employment generally promotes an individual's stability, further research into these variables is essential.</p>","PeriodicalId":20822,"journal":{"name":"Psychiatry (Edgmont (Pa. : Township))","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2010-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2861520/pdf/PE_7_3_12.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"28958872","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The science of epigenetics. 表观遗传学表观遗传学
Psychiatry (Edgmont (Pa. : Township)) Pub Date : 2010-03-01
Assad Meymandi
{"title":"The science of epigenetics.","authors":"Assad Meymandi","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":20822,"journal":{"name":"Psychiatry (Edgmont (Pa. : Township))","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2010-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2861525/pdf/PE_7_3_40.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"28958877","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Capgras syndrome in postictal delirium. 后谵妄中的Capgras综合征。
Psychiatry (Edgmont (Pa. : Township)) Pub Date : 2010-03-01
Devavrat Joshi, Sharad Koirala, Sachin Lamichhane, Anubha Paladugu, Rupinder Johal, Steven Lippmann
{"title":"Capgras syndrome in postictal delirium.","authors":"Devavrat Joshi,&nbsp;Sharad Koirala,&nbsp;Sachin Lamichhane,&nbsp;Anubha Paladugu,&nbsp;Rupinder Johal,&nbsp;Steven Lippmann","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A 34-year-old man with a seizure disorder had not been taking anticonvulsant medications regularly. A previous pattern of recurrent seizures resolved after restarting anticonvulsant drugs. Recent seizure episodes were followed by delirium and presentation of Capgras syndrome. A variety of functional and organic etiologies for Capgras syndrome are known. This syndrome has been documented in cases of postictal delirium. These symptoms along with delirium ended with seizure control once back on anticonvulsant medicines.</p>","PeriodicalId":20822,"journal":{"name":"Psychiatry (Edgmont (Pa. : Township))","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2010-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2861524/pdf/PE_7_3_37.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"28958876","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Generic penetration in the retail atypical antipsychotic market. 非典型抗精神病药零售市场的通用渗透。
Psychiatry (Edgmont (Pa. : Township)) Pub Date : 2010-03-01
Susan Lenderts, Amir H Kalali, Peter Buckley
{"title":"Generic penetration in the retail atypical antipsychotic market.","authors":"Susan Lenderts,&nbsp;Amir H Kalali,&nbsp;Peter Buckley","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In this article, we explore the penetration of generic atypical antipsychotics in the United States market before and after the availability of generic risperidone in July 2008. Analysis suggests that, overall, generic penetration into the atypical antipsychotic market has grown from approximately three percent in January 2008 to more than 25 percent in December 2009. Similar trends are uncovered when branded and generic prescriptions are analyzed by specialty.</p>","PeriodicalId":20822,"journal":{"name":"Psychiatry (Edgmont (Pa. : Township))","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2010-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2861526/pdf/PE_7_3_9.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"28958955","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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