H. Pereira, T. Pereira, V. Almeida, J. Cardoso, J. Maldonado, J. L. Malaquias, J. Simões, C. Correia
{"title":"New instrumentation for cardiovascular risk assessment: The role of pulse wave velocity","authors":"H. Pereira, T. Pereira, V. Almeida, J. Cardoso, J. Maldonado, J. L. Malaquias, J. Simões, C. Correia","doi":"10.1109/ENBENG.2011.6026065","DOIUrl":"https://doi.org/10.1109/ENBENG.2011.6026065","url":null,"abstract":"Over the last years, great emphasis has been placed on the role of arterial stiffness in the development of cardiovascular diseases. This hemodynamic parameter, generally associated to age and blood pressure increase, can be assessed by the measurement of pulse wave velocity (PWV). Currently available devices that measure PWV are expensive and need to be operated by skilled medical staff, reducing the potential of ambulatory setting. This research project aims at developing and testing the sensoring and algorithmic basis of an alternative and non-invasive device for PWV assessment. The proposed device is based on a double-headed sensor probe and allows the assessment of PWV in one single location, providing important information on local arterial hemodynamics. Although studies to validate the clinical use of this system are still required, it has already demonstrated good performance on a dedicated test bench system, capable of reproducing a range of relevant cardiovascular system's properties.","PeriodicalId":206538,"journal":{"name":"1st Portuguese Biomedical Engineering Meeting","volume":"65 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2011-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126264249","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Interaction between anaesthetics and model biomembrane systems","authors":"José Gabriel Paiva, B. Saramago, A. P. Serro","doi":"10.1109/ENBENG.2011.6026093","DOIUrl":"https://doi.org/10.1109/ENBENG.2011.6026093","url":null,"abstract":"Supported layers of vesicles of dimyristoyl and dipalmitoyl phosphatidylcholine containing cholesterol are adequate models for eukaryotic plasma membranes. In this work it was investigated the adsorption of unilamellar vesicles on the surface of oxidized gold, using a QCM-D, AFM and LSCFM. The results of all techniques indicate that a dense layer of intact liposomes irreversibly adsorbs on the gold surface. It was also investigated the interaction of some examples of local and general anaesthetics with these membrane models, using a QCM-D. Lidocaine, tetracaine, ropivacaine and levobupivacaine were chosen as local anaesthetics examples, and propofol as general anaesthetic. Simultaneously, the interaction of the anaesthetics with the same liposomes in suspension was studied, using DSC. The results showed that all the studied anaesthetics interacted with the used models, causing changes such as raised fluidity and depressed phase transition temperature.","PeriodicalId":206538,"journal":{"name":"1st Portuguese Biomedical Engineering Meeting","volume":"29 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2011-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117028448","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Introduction and welcome address","authors":"","doi":"10.1109/enbeng.2011.6026100","DOIUrl":"https://doi.org/10.1109/enbeng.2011.6026100","url":null,"abstract":"Please note: The abstract finder will open a new window with the selected abstract.","PeriodicalId":206538,"journal":{"name":"1st Portuguese Biomedical Engineering Meeting","volume":"124 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131959654","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}