Physiologia Bohemoslovaca最新文献_第7页

Pathophysiology of the pulmonary circulation. 肺循环的病理生理学。

Physiologia Bohemoslovaca Pub Date : 1989-01-01

G Barer

引用次数: 0

Excretory function of denervated kidney after inhibition of prostaglandin synthesis and furosemide administration in conscious dogs. 抑制前列腺素合成和给药速尿后无神经支配的肾的排泄功能。

Physiologia Bohemoslovaca Pub Date : 1989-01-01

R Girchev, K Tzatchev, E Kabakchieva, N Natcheff

{"title":"Excretory function of denervated kidney after inhibition of prostaglandin synthesis and furosemide administration in conscious dogs.","authors":"R Girchev, K Tzatchev, E Kabakchieva, N Natcheff","doi":"","DOIUrl":"","url":null,"abstract":"The experiments were carried out on unanaesthetized dogs with exteriorized ureters for separate urine collection from the left (denervated) and the right (intact) kidney. The osmolality and concentrations of sodium, potassium, calcium, magnesium, zinc, copper, chloride and creatinine were determined in the plasma as well as in the urine of the two kidneys. The function of the denervated and the innervated kidney was compared prior to and after indomethacin administration (5.0 mg/kg b.w.). The excretory function of both kidneys was also compared after furosemide treatment alone (0.5 mg/kg b.w.) as well as indomethacin pretreatment. Renal denervation increased urine flow rate, calcium and copper excretion. After administration, sodium excretion from the denervated kidney was higher than that from the intact one. Calcium excretion of the two kidneys did not differ significantly, while copper excretion from the denervated kidney was diminished, Furosemide administration after pretreatment with indomethacin did not lead to any difference between the denervated and intact kidney. The results show that renal nerves and prostaglandins participate jointly in the regulation of sodium, copper and calcium excretion. Renal prostaglandins do not change the response of the denervated kidney to furosemide as compared to the intact kidney.","PeriodicalId":20547,"journal":{"name":"Physiologia Bohemoslovaca","volume":"38 5","pages":"465-71"},"PeriodicalIF":0.0,"publicationDate":"1989-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13677622","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Erythrocyte insulin receptor characteristics and erythrocyte membrane lipid composition in healthy men. 健康男性红细胞胰岛素受体特征及红细胞膜脂质组成。

Physiologia Bohemoslovaca Pub Date : 1989-01-01

T Pelikánová, M Kohout, J Hilgertová, J Base, I Farská, J Válek

{"title":"Erythrocyte insulin receptor characteristics and erythrocyte membrane lipid composition in healthy men.","authors":"T Pelikánová, M Kohout, J Hilgertová, J Base, I Farská, J Válek","doi":"","DOIUrl":"","url":null,"abstract":"The cell membrane plays an important role in the mechanism of insulin action. To test whether erythrocyte insulin receptor characteristics are related to the erythrocyte membrane lipid composition, 11 healthy volunteers were studied. The relationship between insulin binding to erythrocytes, the number of receptors per cell and the affinity of receptors to insulin on the one hand and total phospholipid fatty acid (FA) composition and cholesterol/phospholipid molar ratio in the erythrocyte membrane on the other hand were evaluated. 1. We found a significant negative correlation between specific insulin binding and the proportion of n-6 essential FA in erythrocyte membrane phospholipids, especially linoleic acid (r = -0.82, p less than 0.01) and arachidonic acid (r = -0.73, p less than 0.05). On the other hand, a significant positive correlation between insulin binding and the proportion of nonessential FA (r = +0.65, p less than 0.05) was seen. Number of receptors per cell and the affinity of receptors were not significantly related to phospholipid FA composition. 2. There was no significant correlation between insulin receptor characteristics and the cholesterol/phospholipid molar ratio in the erythrocyte membrane. The data presented support the hypothesis that the FA pattern of membrane total phospholipids may modify the properties of insulin receptors.","PeriodicalId":20547,"journal":{"name":"Physiologia Bohemoslovaca","volume":"38 5","pages":"419-25"},"PeriodicalIF":0.0,"publicationDate":"1989-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13678439","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of the administration of prostaglandins (PGE2) in the early postnatal period on closure of the ductus arteriosus in the laboratory rat. 产后早期给予前列腺素(PGE2)对实验大鼠动脉导管闭合的影响。

Physiologia Bohemoslovaca Pub Date : 1989-01-01

T Janatová, D Jarkovská, J Hruda, M Samánek, B Ostádal

引用次数: 0

The effect of time, 2-mercaptoethanol and inhibitors of proteases on isolation of cardiac myosin and its properties. 时间、2-巯基乙醇和蛋白酶抑制剂对心肌球蛋白分离及其性质的影响。

Physiologia Bohemoslovaca Pub Date : 1989-01-01

I Syrový

引用次数: 0

Proceedings of the Czechoslovak Physiological Society. Prague, 7-9 February 1989. Abstracts. 捷克斯洛伐克生理学会学报。布拉格，1989年2月7日至9日。摘要。

Physiologia Bohemoslovaca Pub Date : 1989-01-01

引用次数: 0

Coprophagy in young laboratory rat. 幼龄实验大鼠贪食症。

Physiologia Bohemoslovaca Pub Date : 1989-01-01

V Nováková, A Babický

引用次数: 0

pH, pCO2 and NADP changes during aerobic and anaerobic incubation of the brain cortex of young and adult rats. 幼龄和成年大鼠大脑皮层好氧和厌氧孵育过程中pH、pCO2和NADP的变化。

Physiologia Bohemoslovaca Pub Date : 1989-01-01

J Mourek

{"title":"pH, pCO2 and NADP changes during aerobic and anaerobic incubation of the brain cortex of young and adult rats.","authors":"J Mourek","doi":"","DOIUrl":"","url":null,"abstract":"Wistar rats of both sexes, aged 5 and 90-110 days, bred in the author's department, were used for experiments in which pH, pCO2 and NADP changes induced by incubating brain cortex homogenate (30 min at 37 degrees C) under aerobic and anaerobic conditions were studied. The medium was Sörensen's buffer solution, with succinate as substrate. NADP was assayed by determining glucose-6-phosphate dehydrogenase activity, which is NADP-dependent. The pH and pCO2 were determined with an ABL-2 radiometer (Denmark). The NADP extinction curves showed that the adult rat cortex, with or without substrate, always contained significantly less NADP under anaerobic conditions (the amount of its reduced form increased). In 5-day-old rats, the course of changes in the extinction curves was completely analogous to that for adult rats if the tissue was incubated without substrate; in the presence of substrate, the amount of the oxidized form, i.e. of NADP, decreased and there was no difference between the course of extinction changes under anaerobic and aerobic conditions. Similarly, the pH fell significantly less in 5-day-old rats during anaerobic incubation than in adult rats and was practically no different from the pH changes found during aerobic incubation. In addition, we found that the increase in pCO2 during anaerobic incubation of the brain cortex of 5-day-old rats was very small (also compared with aerobic conditions) whereas the increase in pCO2 under aerobic and anaerobic conditions in adult rats was the same.(ABSTRACT TRUNCATED AT 250 WORDS)","PeriodicalId":20547,"journal":{"name":"Physiologia Bohemoslovaca","volume":"38 3","pages":"223-30"},"PeriodicalIF":0.0,"publicationDate":"1989-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13672699","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of the parenteral administration of amino acid solutions in different phases after partial hepatectomy on the initiation and development of liver regeneration in rats. 肝部分切除术后不同时期肠外给予氨基酸溶液对大鼠肝再生的启动和发展的影响。

Physiologia Bohemoslovaca Pub Date : 1989-01-01

P Zivný, J Simek

{"title":"Effect of the parenteral administration of amino acid solutions in different phases after partial hepatectomy on the initiation and development of liver regeneration in rats.","authors":"P Zivný, J Simek","doi":"","DOIUrl":"","url":null,"abstract":"Amino acid solutions enriched with branched-chain amino acids or pure branched-chain amino acid solutions were administered parenterally to female laboratory rats (pre-operative weight 230 +/- 30 g) which had been subjected to 65-70% partial hepatectomy (PH), and specific liver DNA activity, the hepatocyte mitotic index and other indicators of the initiation of liver regeneration were studied. Both solutions were infused in an hourly dose of 3.3 ml/kg body weight, during the following postoperative intervals: 1-6, 7-12, 1-12, 1-18 and 1-24 hours. The control rats continued to be fed on the standard laboratory diet after the operation. The results show that the infusion of an amino acid solution enriched with branched-chain amino acids had an inhibitory effect on the onset of DNA synthesis in the liver 18 hours after partial hepatectomy whatever the administration interval. The situation in the case of pure branched-chain amino acid solutions was the same. Twenty-four hours after PH, neither type of solution, irrespective of the infusion interval, was followed by an increase in DNA synthesis compared with the controls fed on the standard laboratory diet. Neither the hepatocyte mitotic index, nor the total liver DNA concentration, showed any changes indicative of stimulation of the initiation of liver regeneration. An infusion stress effect, evaluated from the decrease in the weight of the thymus, was found chiefly in the case of infusions lasting 12 h or longer.","PeriodicalId":20547,"journal":{"name":"Physiologia Bohemoslovaca","volume":"38 2","pages":"135-43"},"PeriodicalIF":0.0,"publicationDate":"1989-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13674032","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Microcomputer analysis of the intraventricular pressure curve of the isolated rat heart. 离体大鼠心脏室内压力曲线的微机分析。

Physiologia Bohemoslovaca Pub Date : 1989-01-01

F Papousek, F Kolár, B Ostádal, V Pribík

引用次数: 0