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[Osteoplastic thoracoplasty with concomitant pulmonectomy in the surgery of generalized destructive pulmonary tuberculosis]. [胸骨成形术合并肺切除术在广泛性破坏性肺结核手术中的应用]。
Problemy tuberkuleza Pub Date : 2003-01-01
A A Andrenko, D E Omel'chuk
{"title":"[Osteoplastic thoracoplasty with concomitant pulmonectomy in the surgery of generalized destructive pulmonary tuberculosis].","authors":"A A Andrenko,&nbsp;D E Omel'chuk","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The paper analyzes the results of surgical treatment in 155 patients with generalized destructive pulmonary tuberculosis who underwent pulmonectomy concomitantly with different types of thoracoplasties in 1986 to 1999. According to the type of thoracoplasty, all the patients were divided in 3 groups: 1) 38 patients undergone pulmonectomy with concomitant osteoplastic thoracoplasty; 2) 41 patients had pulmonectomy with concomitant extrapleural thoracoplasty; and 3) 76 had pulmonectomy with concomitant intrapleural thoracoplasty. On discharge, the full clinical effect was achieved in 92.2% of the patients from Group 1 with their mortality rates of 2.6, whereas in the control groups (Groups 2 and 3), the efficiency of treatment was less and the mortality rates were higher (82.9 and 4.9% in Group 2 and 76.3% and 3.9% in Group 3, respectively). Long-term results in 132 patients were followed up for 2-15 years. Clinical recovery was stated in 91.2, 77.8, and 83.3% in Groups 1, 2, and 3, respectively.</p>","PeriodicalId":20490,"journal":{"name":"Problemy tuberkuleza","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2003-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22420931","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Molecular genetics of Mycobacterium tuberculosis]. [结核分枝杆菌的分子遗传学]。
Problemy tuberkuleza Pub Date : 2003-01-01
O S Tungusova, A O Mar'iandyshev
{"title":"[Molecular genetics of Mycobacterium tuberculosis].","authors":"O S Tungusova,&nbsp;A O Mar'iandyshev","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":20490,"journal":{"name":"Problemy tuberkuleza","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2003-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22420933","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[New organizational forms of antituberculosis care under present conditions. Results and experience exchange of work in pilot regions. Scientific-and-Practical Conference (Moscow, September 25-27, 2002)]. [当前条件下抗结核护理的新组织形式。]试点地区工作成果和经验交流。科学与实践会议(2002年9月25-27日，莫斯科)。
Problemy tuberkuleza Pub Date : 2003-01-01
V V Erokhin, O V Demikhova, V V Punga, E V Putova
{"title":"[New organizational forms of antituberculosis care under present conditions. Results and experience exchange of work in pilot regions. Scientific-and-Practical Conference (Moscow, September 25-27, 2002)].","authors":"V V Erokhin,&nbsp;O V Demikhova,&nbsp;V V Punga,&nbsp;E V Putova","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":20490,"journal":{"name":"Problemy tuberkuleza","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2003-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22420935","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[On early transfer of new cases of pulmonary tuberculosis to outpatient treatment]. [论肺结核新发病例早期转门诊]。
Problemy tuberkuleza Pub Date : 2003-01-01
I G Ursov, V A Krasnov, T A Borovinskaia, V A Potashova, S L Naryshkina, E G Ron'zhina, T I Petrenko
{"title":"[On early transfer of new cases of pulmonary tuberculosis to outpatient treatment].","authors":"I G Ursov,&nbsp;V A Krasnov,&nbsp;T A Borovinskaia,&nbsp;V A Potashova,&nbsp;S L Naryshkina,&nbsp;E G Ron'zhina,&nbsp;T I Petrenko","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Based on 228 clinical cases, the authors propose procedures for complex two-stage (inpatient and outpatient) treatments of new cases of pulmonary tuberculosis by using intermittent intravenous chemotherapy that makes it possible to have a high therapeutic effect in a short space of time, to reduce the duration of hospital treatment substantially, to on the average 2-4 months, and to ensure controlled chemotherapy at the outpatient stage.</p>","PeriodicalId":20490,"journal":{"name":"Problemy tuberkuleza","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2003-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22422708","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Drug resistant tuberculosis in children and adolescents]. [儿童和青少年的耐药结核病]。
Problemy tuberkuleza Pub Date : 2003-01-01
V A Aksenova, E F Luginova
{"title":"[Drug resistant tuberculosis in children and adolescents].","authors":"V A Aksenova,&nbsp;E F Luginova","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The paper presents the results of a follow-up of children and adolescents who isolate drug-resistant Mycobacterium tuberculosis (MBT) strains of those with manifestations of tuberculosis and preserved sensitivity to antibacterial agents. Bacterial isolation in children and adolescents is scanty and multiple. There is a high rate of resistance to isoniazid, streptomycin, and rifampicin. The vast majority of children and adolescents who isolate drug-resistant MBT strains have been found to contact a patient who also isolate drug-resistant MBT. The drug sensitivity of MBT in patients is identical to that of sources of their contamination. Most patients with drug-resistant tuberculosis have been ascertained as having been registered in dispensaries and treated with drugs, which suggests that the use of chemotherapy in prophylactic doses, particularly in patients contacting a bacterial isolator, does not prevent local tuberculosis.</p>","PeriodicalId":20490,"journal":{"name":"Problemy tuberkuleza","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2003-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22303733","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[The morphofunctional state of the surfactant system in pulmonary tuberculosis]. [肺结核表面活性剂系统的形态功能状态]。
Problemy tuberkuleza Pub Date : 2003-01-01
L N Lepekha, V V Erokhin
{"title":"[The morphofunctional state of the surfactant system in pulmonary tuberculosis].","authors":"L N Lepekha,&nbsp;V V Erokhin","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":20490,"journal":{"name":"Problemy tuberkuleza","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2003-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22383064","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Tuberculosis of the central nervous system in preschool children]. [学龄前儿童中枢神经系统结核]。
Problemy tuberkuleza Pub Date : 2003-01-01
L V Poddubnaia, V G Kononenko, T G Ten'kovskaia, G F Dubakova
{"title":"[Tuberculosis of the central nervous system in preschool children].","authors":"L V Poddubnaia,&nbsp;V G Kononenko,&nbsp;T G Ten'kovskaia,&nbsp;G F Dubakova","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The clinical and X-ray forms of tuberculosis were studied in 1481 patients aged under 7 years who had been treated from 1970 to 2000. Patients with tuberculosis of the central nervous system accounted for 5.5%. In the past 15 years, there was an increase in the share of generalized tuberculosis, more severity of the clinical course of tuberculous meningitis, and a rise in the incidence of deaths from the disease. Children of the first year of life fell ill more frequently. The main causes should be considered to be exogenous superinfection whose role increases under the conditions of an undetected reservoir of tuberculous infection; no biomedical protection as tuberculosis controlling measures; no protection of children from socially disadapted families. A fatal case was recorded in half the patients. The other half was discharged as having rough residual changes in the central nervous system.</p>","PeriodicalId":20490,"journal":{"name":"Problemy tuberkuleza","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2003-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22420928","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Prevalence of tuberculosis and its specific clinical features in children]. [儿童结核病患病率及其特殊临床特征]。
Problemy tuberkuleza Pub Date : 2003-01-01
F T Absadykova, E B Moroz'ko, M K Aĭbekova
{"title":"[Prevalence of tuberculosis and its specific clinical features in children].","authors":"F T Absadykova,&nbsp;E B Moroz'ko,&nbsp;M K Aĭbekova","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A retrospective study of epidemiological indices of tuberculosis in children in the Republic of Uzbekistan for the past 20 years has shown that tuberculosis morbidity rates have increased by 65.4% and by 114% in children living in the foci of tuberculosis infection. The greatest increase in its morbidity rates is observed in the Aral Sea region, which is accompanied by worse social, environmental, and economic situations. Varying tuberculosis courses are revealed in inland children, which makes it necessary to implement tuberculosis controlling measures, especially in the foci of tuberculosis infection.</p>","PeriodicalId":20490,"journal":{"name":"Problemy tuberkuleza","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2003-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22302714","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Effects of immunomodulator leukinferon on the course of experimental tuberculosis]. 免疫调节剂白介素对实验性肺结核病程的影响。
Problemy tuberkuleza Pub Date : 2003-01-01
L E Gedymin, V V Erokhin, L N Lepekha, G M Nikolaeva, G O Kaminskaia, V P Kuznetsov, D L Beliaev, A A Babaiants
{"title":"[Effects of immunomodulator leukinferon on the course of experimental tuberculosis].","authors":"L E Gedymin,&nbsp;V V Erokhin,&nbsp;L N Lepekha,&nbsp;G M Nikolaeva,&nbsp;G O Kaminskaia,&nbsp;V P Kuznetsov,&nbsp;D L Beliaev,&nbsp;A A Babaiants","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>An experiment was conducted on 60 CBA mice intravenously inoculated with cultured Mycobacteria tuberculosis (MBT), Erdmann strain, in a dose of 0.025 mg. The specific features of tissue, cellular, and biochemical reactions were studied in the lung, liver, and spleen when leukinferon (LF) was included into tuberculosis treatment regimen. LF was shown to have a positive impact on the development of reparative reactions during tuberculous inflammation by reducing the time of abacillation and recovering the structure of diseased organs. By month 3 of follow-up, MBT were not detected in mice receiving antibacterial agents (ABA) and LF, while typical and changed forms of LF were identified in the cytoplasm of alveolar macrophages in mice treated with ABA alone. A specific feature of an inflammatory reaction as a significant proliferation of lymphocytes and macrophages with their ample infiltration of target organs was noted in animals receiving LF. This was followed by the activated production of alpha- and gamma-interferons and by the mobilization of an enzymatic link of anti-oxidant defense under chronic oxidative stress, which led to a reduction of resolution of inflammatory areas and to an increase in survival of animals which had not been given ABA, but treated with LF alone.</p>","PeriodicalId":20490,"journal":{"name":"Problemy tuberkuleza","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2003-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22304328","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Significance of molecular genetic and immunological techniques in risk groups and in children with tuberculosis]. [分子遗传学和免疫学技术在危险人群和结核病儿童中的意义]。
Problemy tuberkuleza Pub Date : 2003-01-01
E A Marenina, E S Ovsiankina, E E Larionova, M A Kapina, N V Dem'ianenko, A I Markina, G A Lebedeva
{"title":"[Significance of molecular genetic and immunological techniques in risk groups and in children with tuberculosis].","authors":"E A Marenina,&nbsp;E S Ovsiankina,&nbsp;E E Larionova,&nbsp;M A Kapina,&nbsp;N V Dem'ianenko,&nbsp;A I Markina,&nbsp;G A Lebedeva","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A total of 188 children and adolescents were examined. In all the children, blood Mycobacterium tuberculosis (MBT) DNA was determined by polymerase chain reaction (PCR) and MBT antigens (AG) and antibodies (AB) were by enzyme immunoassay. The studies have shown that it is expedient to concurrently determine MBT DNA and MBT AT in order to identify local forms of tuberculosis in children from risk groups. If the tests are positive, a comprehensive examination for tuberculosis is required; the presence of the syndrome of common disturbances is generally associated with tuberculous infection. When a local form of tuberculosis is excluded, preventive chemotherapy should be performed. Further negative tests for MBT DNA and lower MBT AT may be a criterion for the efficiency of preventive treatment. In children with tuberculosis, the results of repeated blood and urine tests for MBT DNA provide a way of evaluating the course of a tuberculous process and the efficiency of chemotherapy. PCR used to determine blood and urine MBT DNA is a highly specific test as positive results were in 79% of the children with tuberculosis.</p>","PeriodicalId":20490,"journal":{"name":"Problemy tuberkuleza","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2003-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22382532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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