{"title":"Analysis of COVID -19: Where Do We Stand?","authors":"Cornelli Umberto","doi":"10.53902/pwhcij.2021.01.000504","DOIUrl":"https://doi.org/10.53902/pwhcij.2021.01.000504","url":null,"abstract":"Background: The COVID-19 is a real pandemia and only very few countries in the world were minimally affected. Objective: To measure the impact of COVID-19 deaths in 49 countries (49 SC or selected countries) and correlate them with, ecological, demographical, social, economic variables, aging and chronic diseases. Material and methods: The 49 SCs are those considered by WHO reliable in term of deaths records. Data concerning COVID-19 were taken from John Hopkins records updated to December 5th. The ecological, demographical, social, economical variable were consistent with the CIA Fact Book 2020. The deaths due to the most common diseases and cancers were taken from the WHO records in term of ASDRs (Age Standardized Death Rate). The age index was taken from The World Bank. The correlations were calculate in term “r” (linear correlation). Results: The 49 SC represent about 19% of the world population accounting for about 61% of the total worldwide deaths. Very consistent differences among countries were shown, from 0% deaths up to 1.5 % deaths/1000 inhabitants. Any correlation was found with aging and ecological, demographical/social, economic variables. The same was for the most common diseases (a part of peptic ulcer) and cancers (a part of bladder cancer). Conclusion: The COVID-19 seems to be an independent disease, and the efficiency in reducing deaths belongs mainly by political issues.","PeriodicalId":20389,"journal":{"name":"Pregnancy and Women’s Health Care International Journal","volume":"145 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77669042","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lara Passos Alvim, Thaís Izidoro Pires, M. Chaves, C. Savioli, G. Fabri
{"title":"Oral warning signs of elastic pseudoxanthoma","authors":"Lara Passos Alvim, Thaís Izidoro Pires, M. Chaves, C. Savioli, G. Fabri","doi":"10.1177/1745505716666097","DOIUrl":"https://doi.org/10.1177/1745505716666097","url":null,"abstract":"The pseudoxanthoma elasticum is a multisystemic heritable disease that primarily affects the connective tissue. It has been characterized by fragmentation and calcification of elastic fibers that can lead to complications of skin and cardiovascular system and changes in retina. Involvement of the oral mucosa has been described like white patches striated especially in the mucosa of both upper and lower lips. These oral signs are potentially useful to diagnose the disease, since it is an often undiagnosed disease due to the variability in phenotypic expressions. This study reports a case of pseudoxanthoma elasticum affecting a woman who developed lesions in the oral mucosa during the disease progression. Intraoral clinical assessment revealed the presence of changes mainly in lower labial mucosa and also slightly changes in the mouth floor and the upper labial mucosa. Therefore, the acknowledgment of oral pseudoxanthoma elasticum lesions helps dental practitioners to establish an early and appropriate diagnosis of this disease. This is very important because pseudoxanthoma elasticum is a multisystem disease with morbidity and mortality, and its early diagnosis and also the establishment of a follow-up protocol for these patients could prevent systemic and oral complications.","PeriodicalId":20389,"journal":{"name":"Pregnancy and Women’s Health Care International Journal","volume":"148 1","pages":"492 - 495"},"PeriodicalIF":0.0,"publicationDate":"2016-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77819044","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Self-reported short sleep duration and insomnia symptoms as predictors of post-pregnancy weight change: Results from a cohort study","authors":"Kamilla Rognmo, Borge Sivertsen, M. Eberhard-Gran","doi":"10.1177/1745505716668871","DOIUrl":"https://doi.org/10.1177/1745505716668871","url":null,"abstract":"This study aims to investigate whether change in sleep duration and insomnia symptoms in the postpartum period is related to change in body mass index from before to 2 years after pregnancy. This study is based on self-report data from a Norwegian cohort, the AHUS Birth Cohort Study. Data were collected at 8 weeks (T1) and 2 years (T2) postpartum. Data from 812 women were analyzed. The results showed that only women with symptoms of insomnia at both T1 and T2 (persistent symptoms) had a greater increase in body mass index compared to women with no insomnia symptoms at T1 or T2.The results indicate that persistent insomnia symptoms are related to a greater increase in body mass index.","PeriodicalId":20389,"journal":{"name":"Pregnancy and Women’s Health Care International Journal","volume":"98 1","pages":"465 - 474"},"PeriodicalIF":0.0,"publicationDate":"2016-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81037425","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Relation of statin use with non-melanoma skin cancer: Prospective results from the Women’s Health Initiative","authors":"Ange Wang, Jean Y. Tang, M. Stefanick","doi":"10.1177/1745505716667958","DOIUrl":"https://doi.org/10.1177/1745505716667958","url":null,"abstract":"The relationship between the use of statins (3-hydroxy3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors) and multiple cancer types has been the focus of many studies. A recent prospective study by Wang et al.1 investigated the relationship between statin use and non-melanoma skin cancer (NMSC) in the large, prospective Women’s Health Initiative (WHI). NMSC includes basal cell carcinoma (BCC) and squamous cell carcinoma (SCC). Although usually not life-threatening, NMSC is the most common cancer in the United States (over 5.4 million cases yearly) and leads to a high economic burden.2 With the high incidence of NMSC and the 2013 American College of Cardiology/American Heart Association guidelines3 which have increased the indications for statin use in the United States, better understanding of the relationship between statin use and NMSC is particularly important. The WHI study found that among a cohort of 118,357 women, use of any statin at baseline was associated with increased NMSC (odds ratio (OR), 1.21, 1.07–1.35). The study also found that the effect was most pronounced for lipophilic statins (OR 1.39, 1.18–1.64), including lovastatin and simvastatin. Statins carry a photosensitivity warning, and prior clinical studies have suggested that statins may be associated with increased NMSC incidence. In the Scandinavian Simvastatin Survival Study (4S) and the Heart Protection Study (HPS) randomized controlled trials (RCTs), NMSC was found to have a higher incidence in the treatment groups.4,5 A large meta-analysis of RCTs, cohort studies, and case–control studies on statins and all-cancer incidence also found increased NMSC risk among statin users.6 Additionally, two large European studies found increased NMSC or BCC incidence associated with the use of all or particular statin types.7,8 However, some conflicting evidence exists in literature, as other studies including meta-analyses of randomized controlled trials (RCTs) have reported no significant relationship between statin use and NMSC risk,7,9,10 and studies have also suggested decreased NMSC risk associated with statin use.11,12 These conflicting findings are somewhat difficult to put into context, as prospective studies and RCTs investigating this relationship have been limited. In contrast to the findings on skin cancer and statin use, the literature on statin use and other non-cutaneous cancers has mostly reported decreased incidence13–16 or no effect.6,10 Additionally, several studies on cancer mortality and statin use have found protective effects, including a retrospective study of 295,925 cancer patients in Denmark17 and a retrospective study in Finland among 31,114 patients which examined statin use and breast cancer mortality specifically. In contrast, a meta-analysis of RCTs in the Cholesterol Treatment Trialists’ (CTT) Collaboration18 database reported no association between statin use and either cancer mortality or incidence. Nonetheless, overall the literature on stati","PeriodicalId":20389,"journal":{"name":"Pregnancy and Women’s Health Care International Journal","volume":"53 1","pages":"453 - 455"},"PeriodicalIF":0.0,"publicationDate":"2016-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89002554","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Rational study endpoints in anti-neoplastic agent regulatory approval trials in the gynecologic malignancies","authors":"M. Markman","doi":"10.1177/1745505716655555","DOIUrl":"https://doi.org/10.1177/1745505716655555","url":null,"abstract":"A discussion of rational endpoints in clinical trials seeking regulatory approval for new anti-neoplastic agents involving the three major gynecologic malignancies, cancers of the ovary, cervix, and endometrial, is particularly interesting as (in the opinion of this commentator) the conclusion will be different in the individual cancers.","PeriodicalId":20389,"journal":{"name":"Pregnancy and Women’s Health Care International Journal","volume":"240 1","pages":"396 - 399"},"PeriodicalIF":0.0,"publicationDate":"2016-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76926511","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The past, the present, and the future in the gastrointestinal health of women: An interview with Dr Jacqueline L Wolf","authors":"J. Wolf","doi":"10.1177/1745505716655556","DOIUrl":"https://doi.org/10.1177/1745505716655556","url":null,"abstract":"","PeriodicalId":20389,"journal":{"name":"Pregnancy and Women’s Health Care International Journal","volume":"46 1","pages":"393 - 395"},"PeriodicalIF":0.0,"publicationDate":"2016-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89103103","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Qureshi, Mahsa Kanzali, S. Rizvi, Niharika Joolukuntla, B. Fomberstein
{"title":"New diagnosis of rheumatoid arthritis during the third trimester of pregnancy","authors":"S. Qureshi, Mahsa Kanzali, S. Rizvi, Niharika Joolukuntla, B. Fomberstein","doi":"10.1177/1745505716661724","DOIUrl":"https://doi.org/10.1177/1745505716661724","url":null,"abstract":"We report here an unusual case of rheumatoid arthritis presenting for the first time in a 32-week pregnant patient. Despite thorough evaluations from different specialties, the patient’s diagnosis went undiscovered originally being attributed to orthopedic issues and then to normal symptoms of pregnancy. The patient’s symptoms progressively worsened until she was no longer able to ambulate and complete her daily activities. A primary diagnosis of rheumatoid arthritis is exceedingly rare during pregnancy due to changes in the body’s immune system that accommodate the foreign fetus. Also physiologic changes that occur during pregnancy can often cloud the clinical picture of a patient presenting with joint pain and weakness. Nonetheless, a thorough workup should be conducted to rule out underlying rheumatologic disease.","PeriodicalId":20389,"journal":{"name":"Pregnancy and Women’s Health Care International Journal","volume":"12 1","pages":"407 - 411"},"PeriodicalIF":0.0,"publicationDate":"2016-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90940621","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Petrini, N. Pereira, J. Lekovich, R. Elias, S. Spandorfer
{"title":"Early spontaneous multiple fetal pregnancy reduction is associated with adverse perinatal outcomes in in vitro fertilization cycles","authors":"A. Petrini, N. Pereira, J. Lekovich, R. Elias, S. Spandorfer","doi":"10.1177/1745505716658898","DOIUrl":"https://doi.org/10.1177/1745505716658898","url":null,"abstract":"The primary objective of this study is to investigate whether early spontaneous multiple fetal pregnancy reduction, also known as vanishing twin syndrome, is associated with adverse perinatal outcomes in fresh in vitro fertilization cycles. This is a retrospective cohort study of women with live singleton births with and without an early vanishing twin after fresh in vitro fertilization. Characteristics compared included incidence of preterm birth, overall birth weight, overall low birth weight, overall very low birth weight, and term low birth weight. In all, 4049 patients with live singleton births were included—853 and 3196 with and without a vanishing twin, respectively. The vanishing twin group had a lower overall birth weight compared to those without (3279.5 ± 369.9 vs 3368.6 ± 567.5 g; p < 0.01). Early vanishing twin was also associated with an increased odds of overall low birth weight (odds ratio: 1.75; 95% confidence interval: 1.36–2.25; p < 0.01) and increased odds of term low birth weight (odds ratio: 3.44; 95% confidence interval: 2.14–5.53; p < 0.01). Our study suggests that early vanishing twin is associated with lower overall birth weight and higher odds of overall low birth weight and term low birth weight in live singleton births after fresh in vitro fertilization.","PeriodicalId":20389,"journal":{"name":"Pregnancy and Women’s Health Care International Journal","volume":"4 1","pages":"420 - 426"},"PeriodicalIF":0.0,"publicationDate":"2016-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80986383","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Clinical implications of accessory fallopian tube ostium in endometriosis and primary infertility","authors":"N. Pereira, I. Kligman","doi":"10.1177/1745505716658897","DOIUrl":"https://doi.org/10.1177/1745505716658897","url":null,"abstract":"Several variations in fallopian tube anatomy may be noted during the evaluation of infertility. Some anatomical variants such as accessory tubal ostia are rare. A 31-year-old woman presented to our center with a 2-year history of primary infertility. Given her history of dysmenorrhea, a diagnostic laparoscopy was performed. Laparoscopy revealed a left utero-sacral endometriosis implant, which was resected. Although the left fallopian tube was normal, the right fallopian tube was noted to have two prongs with individual ostia. Tubal cannulation confirmed two separate ostia, with chromotubation showing free flow of dye through separate fimbrial ostia of the right fallopian tube. The current case highlights that accessory tubal ostia are rare müllerian duct anomalies seen during laparoscopy and can be associated with endometriois or primary infertility.","PeriodicalId":20389,"journal":{"name":"Pregnancy and Women’s Health Care International Journal","volume":"13 1","pages":"404 - 406"},"PeriodicalIF":0.0,"publicationDate":"2016-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88545248","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Size matters in planning hysterectomy approach","authors":"Yasmina D Mohan, V. Chiu, N. Lonky","doi":"10.1177/1745505716653692","DOIUrl":"https://doi.org/10.1177/1745505716653692","url":null,"abstract":"Hysterectomy is the second most common gynecologic surgery; approximately 600,000 women undergo hysterectomies each year in the United States. Estimated uterine size, either by bimanual examination, ultrasonography, or both, is one of the major factors in evaluating the need for hysterectomy and in selecting the surgical approach. In this article, we review how physician-estimated uterine size can be confidently used in providing optimal hysterectomy care, as data indicate estimation is closely correlated with actual post-surgical pelvic specimen weight.","PeriodicalId":20389,"journal":{"name":"Pregnancy and Women’s Health Care International Journal","volume":"367 1","pages":"400 - 403"},"PeriodicalIF":0.0,"publicationDate":"2016-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80377387","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}