{"title":"An efficient approach to the inpatient Syncope Workup.","authors":"Robert Burgese,Beman Wasef,Daniel Wang","doi":"10.1080/00325481.2024.2406742","DOIUrl":"https://doi.org/10.1080/00325481.2024.2406742","url":null,"abstract":"OBJECTIVEThis review aims to provide hospitalists with a streamlined understanding of the evaluation of syncope, a commonly encountered complaint in hospital medicine.METHODSAuthors conducted a literature review using the keyword 'syncope' to compile current evidence and recommendations regarding the categorization, risk stratification, and diagnostic evaluation of syncope.RESULTSThe review outlines the categorization of syncope into cardiac, neurally-mediated, and orthostatic types, detailing the clinical features, etiologies, and differential diagnoses of each. It provides a structured framework for history-taking, physical examination, orthostatic vital sign assessment, and risk stratification to guide clinicians in efficiently identifying high-risk patients requiring urgent intervention. Diagnostic modalities including electrocardiography, echocardiography, and point-of-care ultrasound are discussed, along with their respective indications and limitations.CONCLUSIONBy embracing standardized approaches and evidence-based practices outlined in this review, hospitalists can optimize resource utilization, streamline patient care, and improve outcomes in patients presenting with syncope.","PeriodicalId":20329,"journal":{"name":"Postgraduate Medicine","volume":"38 1","pages":""},"PeriodicalIF":4.2,"publicationDate":"2024-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142268874","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mark L. Metersky, David Fraulino, Lea Monday, Teena Chopra
{"title":"Current challenges in pulmonary nontuberculous mycobacterial infection: a case series with literature review","authors":"Mark L. Metersky, David Fraulino, Lea Monday, Teena Chopra","doi":"10.1080/00325481.2024.2401766","DOIUrl":"https://doi.org/10.1080/00325481.2024.2401766","url":null,"abstract":"The prevalence of nontuberculous mycobacteria pulmonary disease (NTM-PD), particularly caused by Mycobacterium avium complex (MAC), is rising due to improved diagnostics, increased awareness, and m...","PeriodicalId":20329,"journal":{"name":"Postgraduate Medicine","volume":"27 1","pages":""},"PeriodicalIF":4.2,"publicationDate":"2024-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142200592","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hüseyin Mutlu, Ekrem Taha Sert, Kamil Kokulu, Nazım Abdulkadir Kankılıç
{"title":"Role of the systemic immune-inflammation index in predicting spontaneous stone passage in patients with renal colic","authors":"Hüseyin Mutlu, Ekrem Taha Sert, Kamil Kokulu, Nazım Abdulkadir Kankılıç","doi":"10.1080/00325481.2024.2347198","DOIUrl":"https://doi.org/10.1080/00325481.2024.2347198","url":null,"abstract":"Renal colic (RC) is one of the most frequent reasons for presentation to the emergency department (ED) and creates a high economic and medical burden. Management strategies for RC range from waitin...","PeriodicalId":20329,"journal":{"name":"Postgraduate Medicine","volume":"20 1","pages":""},"PeriodicalIF":4.2,"publicationDate":"2024-04-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140810142","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yanjun Sun, Junfeng Gong, Zhuang Li, Lin Han, Dengqun Sun
{"title":"Gallbladder cancer: surgical treatment, immunotherapy, and targeted therapy","authors":"Yanjun Sun, Junfeng Gong, Zhuang Li, Lin Han, Dengqun Sun","doi":"10.1080/00325481.2024.2345585","DOIUrl":"https://doi.org/10.1080/00325481.2024.2345585","url":null,"abstract":"Gallbladder cancer is a common type of biliary tract tumor. Optimal management for early stage cases typically involves radical excision as the primary treatment modality. Various surgical techniqu...","PeriodicalId":20329,"journal":{"name":"Postgraduate Medicine","volume":"96 1","pages":""},"PeriodicalIF":4.2,"publicationDate":"2024-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140610211","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Da Wang, Jingyao Ren, Yuanyuan Wang, Xiaohua Dong, Shuo Liu, Tianyi Liao, Lihui Zhu, Miao Yu, Hui Cai
{"title":"Splenectomy versus splenic preservation in total gastrectomy for gastric cancer: a systematic review and meta-analysis comparing survival benefits and short-term complications","authors":"Da Wang, Jingyao Ren, Yuanyuan Wang, Xiaohua Dong, Shuo Liu, Tianyi Liao, Lihui Zhu, Miao Yu, Hui Cai","doi":"10.1080/00325481.2024.2333233","DOIUrl":"https://doi.org/10.1080/00325481.2024.2333233","url":null,"abstract":"There is an ongoing debate regarding the comparative merits of splenectomy (SP) and splenic preservation in the surgical management of gastric cancer. This systematic review and meta-analysis aims ...","PeriodicalId":20329,"journal":{"name":"Postgraduate Medicine","volume":"205 1","pages":""},"PeriodicalIF":4.2,"publicationDate":"2024-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140592186","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"New innovations and educational process in undergraduate neurology education in blended learning: readers left wanting more","authors":"Carlos Koudouovoh, Robert L. Joyner Jr.","doi":"10.1080/00325481.2024.2333719","DOIUrl":"https://doi.org/10.1080/00325481.2024.2333719","url":null,"abstract":"Published in Postgraduate Medicine (Just accepted, 2024)","PeriodicalId":20329,"journal":{"name":"Postgraduate Medicine","volume":"3 1","pages":""},"PeriodicalIF":4.2,"publicationDate":"2024-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140173052","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Development of a hybrid hydrogel for submucosal injection in endoscopic resection of gastrointestinal neoplasm: From laboratory to clinical trial.","authors":"Jui-Wen Kang, Po-Jun Chen, Chiung-Yu Chen, Guillermo Riley, Yao-Sheng Wang, Hsin-Yu Kuo, Chiao-Hsiung Chuang","doi":"10.1055/a-2161-2100","DOIUrl":"10.1055/a-2161-2100","url":null,"abstract":"<p><p><b>Background and study aims</b> Submucosal injection solution is essential for successful endoscopic resection of the early gastrointestinal tumor. We evaluated a new endoscopic hydrogel for submucosal injection and its clinical feasibility. <b>Patients and methods</b> A hydrogel (AceGel) containing 0.4% sodium alginate and 2% calcium lactate was developed for ex vivo and animal studies. Subsequently, a prospective, single-arm study was conducted to assess its feasibility and safety in humans. Patients with gastrointestinal neoplasms undergoing endoscopic resection were enrolled. All patients underwent endoscopic surveillance after 4 weeks and outpatient follow-up at week 6. Afterward, they received endoscopic follow-up according to the medical routine. <b>Results</b> In the ex vivo experiments, the submucosal elevation height of AceGel was equivalent to sodium hyaluronate and superior to saline or glycerol. Animal studies showed that the excised wounds healed well without surrounding tissue damage. Twelve patients participated in the clinical trial, including three, two, and seven patients with esophageal, gastric, and colonic lesions, respectively. The mean neoplasm size and submucosal injection volumes were 24.0±8.6 mm and 22.8±19.9 mL, respectively. All patients had adequate wound healing on 4-week surveillance endoscopy, and none had serious adverse events during 6-week follow-up. Moreover, endoscopic follow-up showed complete wound healing after 6 to 46 months without local mucosal inflammation in all patients. <b>Conclusions</b> AceGel is good for endoscopic submucosal injection and demonstrated its usefulness in durable mucosal elevation for endoscopic therapy in preclinical tests. This clinical trial shows its safety and feasibility in all participating patients.</p>","PeriodicalId":20329,"journal":{"name":"Postgraduate Medicine","volume":"43 1","pages":"E1026-E1034"},"PeriodicalIF":2.6,"publicationDate":"2023-11-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11148844/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80809437","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Correspondence on \"Patients with ankylosing spondylitis have high risk of irritable bowel syndrome.\"","authors":"Mei-Chia Chou, I-Ming Jou, Hui-Tzu Chen, Renin Chang","doi":"10.1080/00325481.2023.2277148","DOIUrl":"10.1080/00325481.2023.2277148","url":null,"abstract":"","PeriodicalId":20329,"journal":{"name":"Postgraduate Medicine","volume":" ","pages":"765"},"PeriodicalIF":4.2,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138800152","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Postgraduate MedicinePub Date : 2023-09-01Epub Date: 2023-08-21DOI: 10.1080/00325481.2023.2247280
Jee Min Kim, Ji Yoon Han, Seung Beom Han
{"title":"Acute COVID-19 in unvaccinated children without a history of previous infection during the delta and omicron periods.","authors":"Jee Min Kim, Ji Yoon Han, Seung Beom Han","doi":"10.1080/00325481.2023.2247280","DOIUrl":"10.1080/00325481.2023.2247280","url":null,"abstract":"<p><strong>Background: </strong>The Omicron variant has been the predominant severe acute respiratory syndrome coronavirus 2 variant circulating in Korea since January 2022. This study evaluated and compared the clinical characteristics of children with coronavirus disease 2019 (COVID-19) between the Delta and Omicron periods.</p><p><strong>Methods: </strong>The medical records of children aged < 12 years diagnosed with acute COVID-19 (<2 weeks of symptom onset) at seven university-affiliated hospitals were retrospectively reviewed. Children with a previous history of COVID-19 or vaccination were excluded. The clinical characteristics of the included children during the Delta (1 August 2021 to 15 January 2022) and Omicron (16 January to 30 June 2022) periods were compared.</p><p><strong>Results: </strong>Among the 515 children included in the study, 36 (7.0%) and 479 (93.0%) were diagnosed with COVID-19 during the Delta and Omicron periods, respectively. A total of 142 (27.6%) were hospitalized, and the hospitalization rate was higher during the Delta period than the Omicron period (91.7% vs. 22.8%, <i>p</i> < 0.001). The incidence of fever (<i>p</i> = 0.009), vomiting (<i>p</i> = 0.031), and seizures (<i>p</i> = 0.007) was higher during the Omicron period, whereas the incidence of rhinorrhea (<i>p</i> = 0.027) was higher during the Delta period. Clinical severity and outcomes were comparable between the two periods. During the Omicron period, 6.4% of the hospitalized children received oxygen therapy and 1.8% received intensive care.</p><p><strong>Conclusion: </strong>The incidence of fever and seizures was higher during the Omicron period in pediatric patients without a history of vaccination or previous COVID-19. However, the clinical severity was similar during both periods.</p>","PeriodicalId":20329,"journal":{"name":"Postgraduate Medicine","volume":" ","pages":"727-733"},"PeriodicalIF":4.2,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10028421","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Postgraduate MedicinePub Date : 2023-09-01Epub Date: 2023-09-11DOI: 10.1080/00325481.2023.2256209
Eden Miller, Dominic Raj, Matthew A Cavender, Sherif Mehanna, Tarlan Namvar, Reese Ochsner
{"title":"Cardiorenal care coordination: holistic patient care opportunities in the primary care setting for patients with chronic kidney disease and atherosclerotic cardiovascular disease.","authors":"Eden Miller, Dominic Raj, Matthew A Cavender, Sherif Mehanna, Tarlan Namvar, Reese Ochsner","doi":"10.1080/00325481.2023.2256209","DOIUrl":"10.1080/00325481.2023.2256209","url":null,"abstract":"<p><strong>Objectives: </strong>Chronic kidney disease (CKD) and atherosclerotic cardiovascular disease (ASCVD) are closely linked conditions, and the presence of each condition promotes incidence and progression of the other. In this study, we sought to better understand the medical journey of patients with CKD and ASCVD and to uncover patients' and healthcare providers' (HCPs) perceptions and attitudes toward CKD and ASCVD diagnosis, treatment, and care coordination.</p><p><strong>Methods: </strong>Cross-sectional, US-population-based online surveys were conducted between May 18, 2021, and June 17, 2021, among 239 HCPs (70 of whom were primary care physicians, or PCPs) and 195 patients with CKD and ASCVD.</p><p><strong>Results: </strong>PCPs reported personally diagnosing CKD in 78% and ASVD in 64% of their patients, respectively. PCPs reported they are more likely to serve as the overall coordinator of their patient's care (89%), while slightly more than half of PCPs self-identified as a patient's coordinator of care specifically for CKD (54%) or ASCVD (59%). In contrast, patients viewed their PCP as their coordinator of care for CKD (25%) or ASCVD (9%). PCPs who personally treated patients with CKD and ASCVD most often recalled primarily prescribing or recommending pharmacologic treatments for CKD and ASCVD; however, patients reported that lifestyle modification was the most common treatment modality they had ever used to manage CKD and ASCVD.</p><p><strong>Conclusion: </strong>CKD and ASCVD are interrelated cardiometabolic conditions with underlying risk factors that can be managed in a primary care setting. However, few patients in our study considered their PCP to be the coordinator of their care for CKD or ASCVD. PCPs can and should take a more active role in educating patients and coordinating care for those with CKD and ASCVD.</p>","PeriodicalId":20329,"journal":{"name":"Postgraduate Medicine","volume":" ","pages":"708-716"},"PeriodicalIF":4.2,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10554330","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}