PielPub Date : 2026-10-01Epub Date: 2026-07-17DOI: 10.1016/j.piel.2026.03.015
Andrea Valentina Bernal Quintero, Juan Sebastián Aguilera Donado, Joseph Armando González Pardo, Heribt Saadak Sanchez De Los Reyes
{"title":"Escalas de gravedad en la unidad de cuidados intensivos y sistemas de puntuación específicos de la enfermedad como predictores de mortalidad en adultos con infecciones necrosantes de tejidos blandos. Revisión sistemática y metaanálisis","authors":"Andrea Valentina Bernal Quintero, Juan Sebastián Aguilera Donado, Joseph Armando González Pardo, Heribt Saadak Sanchez De Los Reyes","doi":"10.1016/j.piel.2026.03.015","DOIUrl":"10.1016/j.piel.2026.03.015","url":null,"abstract":"<div><h3>Introduction</h3><div>Necrotizing soft tissue infections are uncommon dermatologic and surgical emergencies, but they are associated with high mortality. In critically ill patients, uncertainty remains regarding which early prognostic scores best predict mortality.</div></div><div><h3>Methods</h3><div>A systematic review and meta-analysis was conducted in accordance with PRISMA 2020. The protocol was registered in PROSPERO (CRD420251272457). Studies including adults with necrotizing soft tissue infections admitted to the intensive care unit that evaluated clinical scores measured at admission or within the first 24 h were included. The search was performed in PubMed/MEDLINE, Web of Science, and Scopus. Risk of bias was assessed using ROBINS-E, and certainty of the evidence was evaluated with GRADE.</div></div><div><h3>Results</h3><div>Twelve observational studies were included, and mortality ranged from 13.8% to 43.8%. Older age (MD 13.95 years; 95% CI: 10.80–17.10), APACHE II (MD 7.74 points; 95% CI: 5.57–9.91), SAPS II (effect per point 0.04; 95% CI: 0.03–0.06), and shock/hypotension (OR 4.15; 95% CI: 2.41–7.14) were associated with higher mortality, whereas LRINEC did not show a statistically significant association (MD 1.14 points; 95% CI: −<!--> <!-->0.12 to 2.41).</div></div><div><h3>Conclusions</h3><div>In adults with necrotizing soft tissue infections admitted to intensive care, mortality is primarily associated with organ dysfunction and early hemodynamic instability rather than with scores based mainly on laboratory parameters, such as LRINEC. In this context, APACHE II and SAPS II appear to be the most useful tools for initial risk stratification, whereas older age and shock constitute markers of greater severity.</div></div>","PeriodicalId":20182,"journal":{"name":"Piel","volume":"41 8","pages":"Pages 738-752"},"PeriodicalIF":0.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149095665","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
PielPub Date : 2026-10-01Epub Date: 2026-07-14DOI: 10.1016/j.piel.2026.03.017
Manuel Gahona Naranjo, Juan Sebastián Rodríguez Safi, Paula Andrea Ramos Chaparro, Paula Andrea Hernández Arias, Paola Gahona Naranjo
{"title":"Aplicaciones clínicas de la administración de fármacos asistida por láser","authors":"Manuel Gahona Naranjo, Juan Sebastián Rodríguez Safi, Paula Andrea Ramos Chaparro, Paula Andrea Hernández Arias, Paola Gahona Naranjo","doi":"10.1016/j.piel.2026.03.017","DOIUrl":"10.1016/j.piel.2026.03.017","url":null,"abstract":"","PeriodicalId":20182,"journal":{"name":"Piel","volume":"41 8","pages":"Pages 819-826"},"PeriodicalIF":0.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149094033","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
PielPub Date : 2026-10-01Epub Date: 2026-08-10DOI: 10.1016/j.piel.2026.02.027
Aina Estany-Bécares, Ariadna Casamitjana-Casabó, Berta Ferrer-Fábrega, Carla Ferrándiz-Pulido
{"title":"Una pápula rosada de nueva aparición en el tronco","authors":"Aina Estany-Bécares, Ariadna Casamitjana-Casabó, Berta Ferrer-Fábrega, Carla Ferrándiz-Pulido","doi":"10.1016/j.piel.2026.02.027","DOIUrl":"10.1016/j.piel.2026.02.027","url":null,"abstract":"","PeriodicalId":20182,"journal":{"name":"Piel","volume":"41 8","pages":"Pages 787-788"},"PeriodicalIF":0.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149094148","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
PielPub Date : 2026-10-01Epub Date: 2026-05-26DOI: 10.1016/j.piel.2026.03.009
Paula Blázquez Pérez, Pablo Recalde Puig, Javier Moreno-Manzanaro García-Calvillo, María Cotarelo Hernández, Obdulia Agustina García Olmedo, Blas Alexis Gómez Dorado
PielPub Date : 2026-10-01Epub Date: 2026-10-08DOI: 10.1016/j.piel.2026.07.001
Ana M. Varela-Baena, Jennifer P. Rueda-Gómez, Jaqueline Cifuentes-Burbano
{"title":"Nódulo blanquecino de larga evolución en el cuarto dedo. Diagnóstico y comentario","authors":"Ana M. Varela-Baena, Jennifer P. Rueda-Gómez, Jaqueline Cifuentes-Burbano","doi":"10.1016/j.piel.2026.07.001","DOIUrl":"10.1016/j.piel.2026.07.001","url":null,"abstract":"","PeriodicalId":20182,"journal":{"name":"Piel","volume":"41 8","pages":"Pages 800-802"},"PeriodicalIF":0.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149095556","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
PielPub Date : 2026-10-01Epub Date: 2026-08-06DOI: 10.1016/j.piel.2026.06.004
Miquel Ribera Pibernat, Santiago Alfonso Zamora, Maria del Mar Ballester Torrens, Sandra Ros Abarca, Francisca Moreno Fernández, Elena Violeta Iborra
{"title":"Adherencia al tratamiento tópico en pacientes con psoriasis en España: resultados de una encuesta nacional","authors":"Miquel Ribera Pibernat, Santiago Alfonso Zamora, Maria del Mar Ballester Torrens, Sandra Ros Abarca, Francisca Moreno Fernández, Elena Violeta Iborra","doi":"10.1016/j.piel.2026.06.004","DOIUrl":"10.1016/j.piel.2026.06.004","url":null,"abstract":"<div><h3>Introduction</h3><div>Adherence to topical treatment for psoriasis is a key determinant of therapeutic effectiveness in real-world clinical practice. However, it is often suboptimal and influenced by multiple patient- and treatment-related factors. The aim of this study was to analyze adherence, perceptions, and needs associated with topical treatment in patients with psoriasis in Spain.</div></div><div><h3>Material and method</h3><div>An observational, descriptive, cross-sectional study was conducted based on a survey of adult patients living in Spain (<em>n</em> = 963). Information was collected on treatment habits and adherence, evaluation of topical treatment, and disease monitoring. Adherence was assessed using two variables: compliance with medical instructions and frequency of missed applications. A comparative analysis of adherence was performed according to age, perceived improvement, number of topical treatments used, receipt of specific information, and fear of corticosteroid use.</div></div><div><h3>Results</h3><div>A total of 73.9% of patients reported applying topical treatment for psoriasis according to medical instructions, and 53.9% stated they never or almost never forgot to apply it. Additionally, 43.5% acknowledged discontinuing treatment when they felt well. Clinical improvement since treatment initiation was reported by 46.0% of participants. Dissatisfaction with treatment outcomes and certain cosmetic characteristics were the most common barriers to adherence. Furthermore, 52.3% of respondents expressed fear of topical corticosteroids, and 74.9% had not participated in choosing the treatment texture. Adherence was higher among patients over 60 years of age, those who perceived improvement with topical treatment, and those who had received specific information about its application.</div></div><div><h3>Conclusions</h3><div>Adherence to topical treatment for psoriasis remains a significant clinical challenge. There are discrepancies between self-perceived adherence and certain patterns of use. Strengthening communication between healthcare professionals and patients, improving therapeutic education, and promoting shared decision-making may help optimize adherence and, consequently, improve clinical outcomes.</div></div>","PeriodicalId":20182,"journal":{"name":"Piel","volume":"41 8","pages":"Pages 697-707"},"PeriodicalIF":0.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149095649","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}