Plastic Surgery International最新文献_第5页

FAMM Flap in Reconstructing Postsurgical Nasopharyngeal Airway Stenosis. FAMM皮瓣重建术后鼻咽气道狭窄。

Plastic Surgery International Pub Date : 2014-01-01 Epub Date: 2014-09-21 DOI: 10.1155/2014/276058

Ferdinand Wanjala Nangole, Stanley Ominde Khainga

{"title":"FAMM Flap in Reconstructing Postsurgical Nasopharyngeal Airway Stenosis.","authors":"Ferdinand Wanjala Nangole, Stanley Ominde Khainga","doi":"10.1155/2014/276058","DOIUrl":"https://doi.org/10.1155/2014/276058","url":null,"abstract":"Introduction. Postsurgical nasopharyngeal airway stenosis can be a challenge to manage. The stenosis could be as a result of any surgical procedure in the nasopharyngeal region that heals extensive scarring and fibrosis. Objective. To evaluate patients with nasopharyngeal stenosis managed with FAMM flap. Study Design. Prospective study of patients with nasopharyngeal stenosis at the Kenyatta National Hospital between 2010 and 2013 managed with FAMM flap. Materials and Methods. Patients with severe nasopharyngeal airway stenosis were reviewed and managed with FAMM flaps at the Kenyatta National Hospital. Postoperatively they were assessed for symptomatic improvement in respiratory distress, patency of the nasopharyngeal airway, and donor site morbidity. Results. A total of 8 patients were managed by the authors in a duration of 4 years with nasopharyngeal stenosis. Five patients were managed with unilateral FAMM flaps in a two-staged surgical procedure. Four patients had complete relieve of the airway obstruction with a patent airway created. One patient had a patent airway created though with only mild improvement in airway obstruction. Conclusion. FAMM flap provides an alternative in the management of postsurgical severe nasopharyngeal stenosis. It is a reliable flap that is easy to raise and could provide adequate epithelium for the stenosed pharynx. ","PeriodicalId":20105,"journal":{"name":"Plastic Surgery International","volume":"2014 ","pages":"276058"},"PeriodicalIF":0.0,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2014/276058","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32757949","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 9

One-stop outpatient management of accessory auricle in children with titanium clip. 钛夹儿童副耳廓一站式门诊管理。

Plastic Surgery International Pub Date : 2014-01-01 Epub Date: 2014-04-01 DOI: 10.1155/2014/780394

Phui Yee Wong, Tereze Laing, Catherine Milroy

{"title":"One-stop outpatient management of accessory auricle in children with titanium clip.","authors":"Phui Yee Wong, Tereze Laing, Catherine Milroy","doi":"10.1155/2014/780394","DOIUrl":"https://doi.org/10.1155/2014/780394","url":null,"abstract":"Introduction. Literature on ideal management of accessory auricles is limited. Traditionally, accessory auricles are managed by paediatricians with suture ligation at the base of the accessory auricle to induce ischaemic necrosis (Mehmi et al, 2007). This method can be associated with complications and poor cosmesis thus leading to the vogue of surgical excision ( Frieden et al, 1995; Sebben, 1989). We present our experience in managing these lesions in children with the application of a titanium clip in a one-stop outpatient setting. Methods. Data was collected retrospectively through review of patient records and telephone questionnaire identifying outcomes from the parents' perspective. Results. Of 42 patients, 24 (57.1%) responded. Eleven (26.2%) underwent surgical excision, 6 (14.3%) had no intervention, and 1 (2.4%) was not contactable. All parents were happy with the outcome and would recommend this management to other parents. Twenty-three (96%) had no complications apart from a tiny residual nubbin, which was considered cosmetically acceptable. One child had a residual nubbin that grew in size requiring surgical excision at later stage. Conclusion. Management of accessory auricles by the application of a titanium clip in one-stop outpatient setting is safe, simple, quick, and well tolerated with no need for admission, anaesthesia, or followup due to the low complication rate. ","PeriodicalId":20105,"journal":{"name":"Plastic Surgery International","volume":"2014 ","pages":"780394"},"PeriodicalIF":0.0,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2014/780394","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32318076","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Clinical Outcomes for Breast Cancer Patients Undergoing Mastectomy and Reconstruction with Use of DermACELL, a Sterile, Room Temperature Acellular Dermal Matrix. 使用DermACELL(一种无菌的室温脱细胞真皮基质)进行乳房切除术和乳房重建的乳腺癌患者的临床结果

Plastic Surgery International Pub Date : 2014-01-01 Epub Date: 2014-03-11 DOI: 10.1155/2014/704323

Christopher Vashi

{"title":"Clinical Outcomes for Breast Cancer Patients Undergoing Mastectomy and Reconstruction with Use of DermACELL, a Sterile, Room Temperature Acellular Dermal Matrix.","authors":"Christopher Vashi","doi":"10.1155/2014/704323","DOIUrl":"https://doi.org/10.1155/2014/704323","url":null,"abstract":"Background. Decellularized human skin has been used in a variety of medical applications, primarily involving soft tissue reconstruction, wound healing, and tendon augmentation. Theoretically, decellularization removes potentially immunogenic material and provides a clean scaffold for cellular and vascular in growth. The use of acellular dermal matrix in two-stage postmastectomy breast reconstruction is described. Methods. Ten consecutive breast cancer patients were treated with mastectomies and immediate reconstruction from August to November 2011. There were 8 bilateral and 1 unilateral mastectomies for a total of 17 breasts, with one exclusion for chronic tobacco use. Reconstruction included the use of a new 6 × 16 cm sterile, room temperature acellular dermal matrix patch (DermACELL) soaked in a cefazolin bath. Results. Of the 17 breasts, 15 reconstructions were completed; 14 of them with expander to implant sequence and acellular dermal matrix. Histological analysis of biopsies obtained during trimming of the matrix at the second stage appeared nonremarkable with evidence of normal healing, cellularity, and vascular infiltration. Conclusion. Postoperative observations showed that this cellular dermal matrix appears to be an appropriate adjunct to reconstruction with expanders. This acellular dermal matrix appeared to work well with all patients, even those receiving postoperative chemotherapy, postoperative radiation, prednisone, or warfarin sodium. ","PeriodicalId":20105,"journal":{"name":"Plastic Surgery International","volume":"2014 ","pages":"704323"},"PeriodicalIF":0.0,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2014/704323","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32266117","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 20

Skin sparing mastectomy with preservation of nipple areola complex and immediate breast reconstruction in patients with breast cancer: a single centre prospective study. 乳腺癌患者保留皮肤乳房切除术保留乳头乳晕复体和立即乳房重建:一项单中心前瞻性研究。

Plastic Surgery International Pub Date : 2014-01-01 Epub Date: 2014-11-11 DOI: 10.1155/2014/589068

Debarati Chattopadhyay, Souradip Gupta, Prabir Kumar Jash, Marang Buru Murmu, Sandipan Gupta

{"title":"Skin sparing mastectomy with preservation of nipple areola complex and immediate breast reconstruction in patients with breast cancer: a single centre prospective study.","authors":"Debarati Chattopadhyay, Souradip Gupta, Prabir Kumar Jash, Marang Buru Murmu, Sandipan Gupta","doi":"10.1155/2014/589068","DOIUrl":"https://doi.org/10.1155/2014/589068","url":null,"abstract":"Background. Skin and nipple areola sparing mastectomy (NASM) has recently gained popularity as the management of breast cancer. This study aims to evaluate the aesthetic outcome, patient satisfaction, and oncological safety of NASM. Methods. The study prospectively analyzes the results of NASM and immediate breast reconstruction in 34 women with breast cancer. The criteria for inclusion were core biopsy-proven, peripherally located breast cancer of any tumor size and with any \"N\" status, with documented negative intraoperative frozen section biopsy of retroareolar tissue, and distance from the nipple to tumor margin >2 cm on mammography. Results. The median age of the patients was 45 years. The majority had either stage II or stage III breast cancer. The median mammographic distance of tumor from nipple areola complex (NAC) was 3.8 cm. The overall operative morbidity was minimal. The NAC could be preserved in all the patients. There was no local recurrence of tumor at median follow-up of 28.5 months. The aesthetic outcomes were satisfactory. Conclusion. NASM and immediate breast reconstruction can be successfully achieved with minimal morbidity and very low risk of local recurrence in appropriately selected breast cancer patients, with acceptable aesthetic results and good patient satisfaction. ","PeriodicalId":20105,"journal":{"name":"Plastic Surgery International","volume":"2014 ","pages":"589068"},"PeriodicalIF":0.0,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2014/589068","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32882667","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 21

Risk factors and surgical refinements of postresective mandibular reconstruction: a retrospective study. 危险因素和术后下颌骨重建的外科改进:一项回顾性研究。

Plastic Surgery International Pub Date : 2014-01-01 Epub Date: 2014-08-06 DOI: 10.1155/2014/893746

Akiko Sakakibara, Kazunobu Hashikawa, Satoshi Yokoo, Shunsuke Sakakibara, Takahide Komori, Shinya Tahara

{"title":"Risk factors and surgical refinements of postresective mandibular reconstruction: a retrospective study.","authors":"Akiko Sakakibara, Kazunobu Hashikawa, Satoshi Yokoo, Shunsuke Sakakibara, Takahide Komori, Shinya Tahara","doi":"10.1155/2014/893746","DOIUrl":"https://doi.org/10.1155/2014/893746","url":null,"abstract":"Background. Postresective mandibular reconstruction is common in cases of oral and mandibular tumors. However, complications such as infection, plate exposure, or plate fracture can occur. We identified several significant risk factors of complications after reconstructive surgery and compared the effectiveness of different surgical techniques for reducing the incidence of complications. Methods. This study is a retrospective analysis of 28 oromandibular cancer cases that required reconstructive surgery between January 1999 and December 2011 at Kobe University Graduate School of Medicine in Japan. All cases were classified using Hashikawa's CAT and Eichner's classification methods. Then, we determined whether these classifications and different treatment or surgical methods were significantly related to complications. Results. Complications after mandibular reconstruction occurred in 10/28 patients (36%). Specifically, five patients had plate fractures, four had plate exposures, and one had an infection. Radiation therapy and closure without any flaps were significantly related to infection or plate exposure. The wrap-around technique of securing reconstruction plates was used in 14 cases, whereas the run-through technique was used in two cases. Conclusions. The success of mandibular reconstruction depends on both mechanical and biological factors, such as the location of defects, presence of occlusions, and the amount of vascularization of the flap. ","PeriodicalId":20105,"journal":{"name":"Plastic Surgery International","volume":"2014 ","pages":"893746"},"PeriodicalIF":0.0,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2014/893746","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32674755","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 20

The effectiveness of modified cottle maneuver in predicting outcomes in functional rhinoplasty. 改良鼻翼手法预测功能性鼻整形预后的有效性。

Plastic Surgery International Pub Date : 2014-01-01 Epub Date: 2014-08-25 DOI: 10.1155/2014/618313

Elaine Fung, Paul Hong, Corey Moore, S Mark Taylor

{"title":"The effectiveness of modified cottle maneuver in predicting outcomes in functional rhinoplasty.","authors":"Elaine Fung, Paul Hong, Corey Moore, S Mark Taylor","doi":"10.1155/2014/618313","DOIUrl":"https://doi.org/10.1155/2014/618313","url":null,"abstract":"Objective. To assess the outcomes of functional rhinoplasty for nasal valve incompetence and to evaluate an in-office test used to select appropriate surgical techniques. Methods. Patients with nasal obstruction due to nasal valve incompetence were enrolled. The modified Cottle maneuver was used to assess the internal and external nasal valves to help select the appropriate surgical method. The rhinoplasty outcomes evaluation (ROE) form and a 10-point visual analog scale (VAS) of nasal breathing were used to compare preoperative and postoperative symptoms. Results. Forty-nine patients underwent functional rhinoplasty evaluation. Of those, 35 isolated batten or spreader grafts were inserted without additional procedures. Overall mean ROE score increased significantly (P < 0.0001) from 41.9 ± 2.4 to 81.7 ± 2.5 after surgery. Subjective improvement in nasal breathing was also observed with the VAS (mean improvement of 4.5 (95% CI 3.8-5.2) from baseline (P = 0.000)). Spearman rank correlation between predicted outcomes using the modified Cottle maneuver and postoperative outcomes was strong for the internal nasal valve (Rho = 0.80; P = 0.0029) and moderate for the external nasal valve (Rho = 0.50; P = 0.013). Conclusion. Functional rhinoplasty improved subjective nasal airflow in our population. The modified Cottle maneuver was effective in predicting positive surgical outcomes. ","PeriodicalId":20105,"journal":{"name":"Plastic Surgery International","volume":"2014 ","pages":"618313"},"PeriodicalIF":0.0,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2014/618313","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32685832","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 46

Treatment of early-stage pressure ulcers by using autologous adipose tissue grafts. 自体脂肪组织移植治疗早期压疮。

Plastic Surgery International Pub Date : 2014-01-01 Epub Date: 2014-04-10 DOI: 10.1155/2014/817283

Giovanni Francesco Marangi, Tiziano Pallara, Barbara Cagli, Emiliano Schena, Francesco Giurazza, Elio Faiella, Bruno Beomonte Zobel, Paolo Persichetti

{"title":"Treatment of early-stage pressure ulcers by using autologous adipose tissue grafts.","authors":"Giovanni Francesco Marangi, Tiziano Pallara, Barbara Cagli, Emiliano Schena, Francesco Giurazza, Elio Faiella, Bruno Beomonte Zobel, Paolo Persichetti","doi":"10.1155/2014/817283","DOIUrl":"https://doi.org/10.1155/2014/817283","url":null,"abstract":"Assessing pressure ulcers (PUs) in early stages allows patients to receive safer treatment. Up to now, in addition to clinical evaluation, ultrasonography seems to be the most suitable technique to achieve this goal. Several treatments are applied to prevent ulcer progression but none of them is totally effective. Furthermore, the in-depth knowledge of fat regenerative properties has led to a wide use of it. With this study the authors aim at introducing a new approach to cure and prevent the worsening of early-stage PUs by using fat grafts. The authors selected 42 patients who showed clinical and ultrasonographic evidence of early-stage PUs. Values of skin thickness, fascial integrity, and subcutaneous vascularity were recorded both on the PU area and the healthy trochanteric one, used as control region. Fat grafting was performed on all patients. At three months, abnormal ultrasonographic findings, such as reduction of cutaneous and subcutaneous thickness, discontinuous fascia, and decrease in subcutaneous vascularity, all were modified with respect to almost all the corresponding parameters of the control region. Results highlight that the use of fat grafts proved to be an effective treatment for early-stage PUs, especially in the care of neurological and chronic bedridden patients. ","PeriodicalId":20105,"journal":{"name":"Plastic Surgery International","volume":"2014 ","pages":"817283"},"PeriodicalIF":0.0,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2014/817283","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32333201","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 25

Outcome of split thickness skin grafting and multiple z-plasties in postburn contractures of groin and perineum: a 15-year experience. 分厚皮移植和多次z形成形术治疗烧伤后腹股沟和会阴挛缩的疗效:15年的经验。

Plastic Surgery International Pub Date : 2014-01-01 Epub Date: 2014-05-21 DOI: 10.1155/2014/358526

Wani Sajad, Raashid Hamid

{"title":"Outcome of split thickness skin grafting and multiple z-plasties in postburn contractures of groin and perineum: a 15-year experience.","authors":"Wani Sajad, Raashid Hamid","doi":"10.1155/2014/358526","DOIUrl":"https://doi.org/10.1155/2014/358526","url":null,"abstract":"Background. Groin and perineal burn contracture is a rare postburn sequel. Such postburn contractures causes distressing symptoms to the patients and in the management of these contractures, both functional and cosmetic appearance should be the primary concern. Aims. To study the outcome of surgical treatment (STSG and multiple Z-plasties) in postburn contractures of groin and perineum. Material and Methods. We conducted a study of 49 patients, with postburn groin and perineal contractures. Release of contracture with split thickness skin grafting (STSG) was done in 44 (89.79%) patients and release of contracture and closure by multiple Z-plasties was done in 5 (10.21%) patients. Results. Satisfactory functional and cosmetic outcome was seen in 44 (89.79%) patients. Minor secondary contractures of the graft were seen in 3 (6.81%) patients who were managed by physiotherapy and partial recurrence of the contracture in 4 (8.16%) patients required secondary surgery. Conclusion. We conclude that postburn contractures of the groin and perineum can be successfully treated with release of contracture followed by STSG with satisfactory functional and cosmetic results. Long term measures like regular physiotherapy, use of pressure garments, and messaging with emollient creams should not be neglected and should be instituted postoperatively to prevent secondary contractures of the graft and recurrence of the contracture. ","PeriodicalId":20105,"journal":{"name":"Plastic Surgery International","volume":"2014 ","pages":"358526"},"PeriodicalIF":0.0,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2014/358526","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32456957","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Catastrophic Outcomes in Free Tissue Transfer: A Six-Year Review of the NSQIP Database. 游离组织移植的灾难性结果：NSQIP 数据库六年回顾。

Plastic Surgery International Pub Date : 2014-01-01 Epub Date: 2014-11-16 DOI: 10.1155/2014/704206

David W Grant, Alexei Mlodinow, Jon P Ver Halen, John Y S Kim

{"title":"Catastrophic Outcomes in Free Tissue Transfer: A Six-Year Review of the NSQIP Database.","authors":"David W Grant, Alexei Mlodinow, Jon P Ver Halen, John Y S Kim","doi":"10.1155/2014/704206","DOIUrl":"10.1155/2014/704206","url":null,"abstract":"Background. No studies report robust data on the national incidence and risk factors associated with catastrophic medical outcomes following free tissue transfer. Methods. The American College of Surgeons (ACS) multicenter, prospective National Surgical Quality Improvement Program (NSQIP) database was used to identify patients who underwent free tissue transfer between 2006 and 2011. Multivariable logistic regression was used for statistical analysis. Results. Over the 6-year study period 2,349 patients in the NSQIP database underwent a free tissue transfer procedure. One hundred and twenty-two patients had at least one catastrophic medical outcome (5.2%). These 122 patients had 151 catastrophic medical outcomes, including 93 postoperative respiratory failure events (4.0%), 14 pulmonary emboli (0.6%), 13 septic shock events (0.5%), 12 myocardial infarctions (0.5%), 6 cardiac arrests (0.3%), 4 strokes (0.2%), 1 coma (0.0%), and 8 deaths (0.3%). Total length of hospital stay was on average 14.7 days longer for patients who suffered a catastrophic medical complication (P < 0.001). Independent risk factors were identified. Conclusions. Free tissue transfer is a proven and safe technique. Catastrophic medical complications were infrequent but added significantly to length of hospital stay and patient morbidity. ","PeriodicalId":20105,"journal":{"name":"Plastic Surgery International","volume":"2014 ","pages":"704206"},"PeriodicalIF":0.0,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4248358/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32882668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The effect of different topical agents (silver sulfadiazine, povidone-iodine, and sodium chloride 0.9%) on burn injuries in rats. 不同外用药物（磺胺嘧啶银、聚维酮碘和 0.9%氯化钠）对大鼠烧伤的影响。

Plastic Surgery International Pub Date : 2014-01-01 Epub Date: 2014-09-29 DOI: 10.1155/2014/907082

Emir Burak Yüksel, Alpagan Mustafa Yıldırım, Ali Bal, Tuncay Kuloglu

{"title":"The effect of different topical agents (silver sulfadiazine, povidone-iodine, and sodium chloride 0.9%) on burn injuries in rats.","authors":"Emir Burak Yüksel, Alpagan Mustafa Yıldırım, Ali Bal, Tuncay Kuloglu","doi":"10.1155/2014/907082","DOIUrl":"10.1155/2014/907082","url":null,"abstract":"It was aimed to comparatively evaluate the effects of dressing methods with silver sulfadiazine, povidone-iodine, and saline which have a common use in routine practices for burn injuries. Twenty-eight Sprague Dawley adult female rats were used in this study. All the rats were divided into 4 groups: the control group, the povidone-iodine group, the saline group, and the silver sulfadiazine group. On each rat, a second degree burn which covered less than 10% of the body surface area was created under general anesthesia by a metal comb including four probes with 2 × 1 cm area. The control group did not have any treatment during the experiment. Povidone-iodine, saline, and silver sulfadiazine administrations were performed under ether anesthesia every day. On 0, 7th, 14th, and 21st days of the study, tissue samples were taken for histological analyses. The sections taken from the paraffin blocks were stained and avidin-biotin-peroxidase method was used for collagen immune-reactivity. In the light microscope analyses, number of inflammatory cells, vascularization, fibroblast proliferation, collagen formation and epithelialization were evaluated histologically in all groups and analysed statistically. The agents that we used for injury healing in the treatment groups did not show any significant better results in comparison with the control group. In conclusion, further studies with the use of sodium chloride, silver sulfadiazine, and povidone-iodine by creating deeper and/or larger burn injury models are needed in order to accept these agents in routine treatment. ","PeriodicalId":20105,"journal":{"name":"Plastic Surgery International","volume":"2014 ","pages":"907082"},"PeriodicalIF":0.0,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4195403/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32758387","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0