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The piroxicam enigma. 吡罗西康之谜。
Photo-dermatology Pub Date : 1989-08-01
B Ljunggren
{"title":"The piroxicam enigma.","authors":"B Ljunggren","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":20061,"journal":{"name":"Photo-dermatology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1989-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13675486","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Testing the efficacy of sunscreens: effect of choice of source and spectral power distribution of ultraviolet radiation, and choice of endpoint. 测试防晒霜的功效:紫外线辐射源的选择和光谱功率分布的影响，以及终点的选择。
Photo-dermatology Pub Date : 1989-08-01
F Urbach
{"title":"Testing the efficacy of sunscreens: effect of choice of source and spectral power distribution of ultraviolet radiation, and choice of endpoint.","authors":"F Urbach","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The problems inherent in testing the protective efficacy of sunscreens are reviewed. Of primary importance are: the spectral power distribution of the test light source, which should simulate the ultraviolet radiation of midlatitude, midsummer sunlight; definition of minimal erythema of skin, and equilibration of light source and filters prior to testing.</p>","PeriodicalId":20061,"journal":{"name":"Photo-dermatology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1989-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13729092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Dynamics of systemic quinidine photoallergy in the mouse. 小鼠全身奎尼丁光过敏动力学。
Photo-dermatology Pub Date : 1989-08-01
B Ljunggren, L E Wirestrand
{"title":"Dynamics of systemic quinidine photoallergy in the mouse.","authors":"B Ljunggren,&nbsp;L E Wirestrand","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Photoallergy to systemically administered quinidine was induced in the mouse, and the minimal time for sensitization as well as the duration of the allergy were studied. When groups of female albino mice, pretreated with cyclophosphamide, were exposed to quinidine 100 mg/kg i.p. followed by 0.1 J/cm2 UVB and 5.0 J/cm2 UVA, a positive challenge reaction, measured as ear edema, could be registered as early as the third day after induction and peaked on days 5-12. When animals photosensitized as above were photochallenged after 7 days, and again after 2 and 8 months, strong reactions were obtained on all 3 occasions, suggesting a duration of systemically induced photoallery to quinidine of more than 8 months. In the absence of quinidine, no photosensitivity could be demonstrated with UVA only. Phototoxicity controls were negative. These results suggest that photoallergy induced by systemic administration behaves similarly to contact and photocontact allergy.</p>","PeriodicalId":20061,"journal":{"name":"Photo-dermatology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1989-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13675488","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Extracorporeal photochemotherapy: indications, methodology, safety aspects, side effects and long-term results. 体外光化学疗法:适应症，方法，安全性，副作用和长期结果。
Photo-dermatology Pub Date : 1989-08-01
P Heald, M Perez, G McKiernan, I Christiensen, R Edelson
{"title":"Extracorporeal photochemotherapy: indications, methodology, safety aspects, side effects and long-term results.","authors":"P Heald,&nbsp;M Perez,&nbsp;G McKiernan,&nbsp;I Christiensen,&nbsp;R Edelson","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":20061,"journal":{"name":"Photo-dermatology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1989-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13675489","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Photoallergic reaction induced by piroxicam. 吡罗西康致光过敏反应。
Photo-dermatology Pub Date : 1989-08-01
A Sunohara, N Mizuno, Y Kawabe, S Sakakibara
{"title":"Photoallergic reaction induced by piroxicam.","authors":"A Sunohara,&nbsp;N Mizuno,&nbsp;Y Kawabe,&nbsp;S Sakakibara","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":20061,"journal":{"name":"Photo-dermatology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1989-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13675491","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Antiviral properties of photosensitizers used in dermatology: recent advances and alternative interpretations. 皮肤病学中使用的光敏剂的抗病毒特性:最新进展和替代解释。
Photo-dermatology Pub Date : 1989-08-01
J B Hudson
{"title":"Antiviral properties of photosensitizers used in dermatology: recent advances and alternative interpretations.","authors":"J B Hudson","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":20061,"journal":{"name":"Photo-dermatology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1989-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13826099","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Drug fever caused by 8-methoxypsoralen. 8-甲氧基补骨脂素引起的药热。
Photo-dermatology Pub Date : 1989-06-01
M Berg
{"title":"Drug fever caused by 8-methoxypsoralen.","authors":"M Berg","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":20061,"journal":{"name":"Photo-dermatology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1989-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13902227","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Haemodialysis photosensitivity. 血液透析光敏性。
Photo-dermatology Pub Date : 1989-06-01
C D Anderson
{"title":"Haemodialysis photosensitivity.","authors":"C D Anderson","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":20061,"journal":{"name":"Photo-dermatology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1989-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13810092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ultraviolet radiation at high latitudes and the risk of skin cancer. 高纬度地区的紫外线辐射和患皮肤癌的风险。
Photo-dermatology Pub Date : 1989-06-01
K Henriksen, K Stamnes, G Volden, E S Falk
{"title":"Ultraviolet radiation at high latitudes and the risk of skin cancer.","authors":"K Henriksen,&nbsp;K Stamnes,&nbsp;G Volden,&nbsp;E S Falk","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Solar irradiance in the spectral region 280 to 800 nm was measured with a double monochromator at 2 locations in Norway, Tromsø (69.7 degrees N) and Longyearbyen (78.2 degrees N). During the observational (midnight sun) period in Longyearbyen, the maximum UVB irradiance recorded was less than 0.3 W/m2, and no radiation was detected for wavelengths below 300 nm. Such low levels are believed to be a consequence of the low solar elevation angle and the high ozone content of the Arctic ozone layer, which absorbs the incident UV light. With levels between 280 and 350 DU over the period of study, Tromsø and Longyearbyen recorded only one-ninth of the calculated UVB radiation at the equator. There is therefore a considerably higher risk of radiation damage to the skin in equatorial regions (controlling for skin type), a finding that agrees with the statistical evidence for a 7-8 times higher rate of skin cancer in the white population of equatorial countries.</p>","PeriodicalId":20061,"journal":{"name":"Photo-dermatology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1989-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13900722","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sunscreen testing using the mouse ear model. 使用小鼠耳模型进行防晒测试。
Photo-dermatology Pub Date : 1989-06-01
C A Cole, P D Forbes, K Ludwigsen
{"title":"Sunscreen testing using the mouse ear model.","authors":"C A Cole,&nbsp;P D Forbes,&nbsp;K Ludwigsen","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>During the developmental stages of sunscreen formulation it is desirable to have a simple, accurate and inexpensive biological model to test product effectiveness. Another desirable attribute is a quantitative, unbiased response endpoint for evaluation. We have developed such a test system based upon the ear swelling response of hairless albino mice. With this system, irradiation times are greatly reduced; furthermore, the response parameter is metric and can be determined noninvasively with an inexpensive micrometer. Protection factors determined with the mouse ear model show high correlation with the sun protection factors as determined on human subjects (r = 0.92) and were linearly related over a wide range of values. This new method affords a simple, accurate and inexpensive system for evaluation of efficacy and safety of new products.</p>","PeriodicalId":20061,"journal":{"name":"Photo-dermatology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1989-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13902220","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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