{"title":"Protective Effect of Melaleuca alternifolia Essential Oil on Broiler Growth Performance, Intestinal Morphology, Gut Microflora, and Gut Redox Status: An Alternative Growth Promoter to Antibiotics","authors":", , and, Xiaofeng Zhang, Lihua Huang, Haiyan Ling, Liping Zhou","doi":"10.17582/journal.pjz/20240516020220","DOIUrl":"https://doi.org/10.17582/journal.pjz/20240516020220","url":null,"abstract":"This study aimed to investigate the impact of brewer's yeast supplementation on the productive performance, rumen fermentation, and serum antioxidant capacity of Simmental Charolais crossbred beef cattle. Forty healthy beef cattle with same body weights (201 6 kg) were randomly assigned to either a control group (CON) or a brewer's yeast (100 g/head/day) supplementation group (SC), each consisting of 20 animals. The experimental period spanned 120 days. Results revealed significant improvements in the SC group compared to the CON group. Specifically, the final body weight (P=0.043) and average daily gain (P=0.027) of the beef cattle in the SC group significantly increased, while the feed conversion ratio demonstrated a significant reduction (P=0.003). Furthermore, the rumen fermentation profile of the SC group indicated noteworthy alterations, with significantly higher concentrations of acetic acid (P<0.001), total volatile fatty acids (P<0.001), and an increased acetic acid/propionic acid ratio (P=0.021), coupled with a significant decrease in ammonia peptide nitrogen content (P<0.001). In terms of serum antioxidant capacity, the SC group exhibited significantly greater concentrations of total antioxidant capacity, total superoxide dismutase, and glutathione peroxidase compared to the control group (P<0.05). Conversely, malondialdehyde levels were significantly lower in the SC group (P<0.001). In conclusion, the incorporation of brewer's yeast into the diet of beef cattle yielded substantial improvements in growth performance, rumen fermentation characteristics, and antioxidant levels. These findings underscore the potential of brewer's yeast supplementation as a beneficial dietary strategy in enhancing the overall health and productivity of Simmental Charolais crossbred beef cattle.","PeriodicalId":19975,"journal":{"name":"Pakistan Journal of Zoology","volume":"58 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://researcherslinks.com/uploads/articles/1735908675_PJZ_MH20240110151005-R1_Jiang et al.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147891493","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Preservation of Hairtail (Trichiurus lepturus) Using Water Soluble Chitosan Based Coatings Combined with Tea Polyphenols","authors":"Yunqian He, Yu Liu, Xiang Li, Shengjun Wu","doi":"10.17582/journal.pjz/20240601234442","DOIUrl":"https://doi.org/10.17582/journal.pjz/20240601234442","url":null,"abstract":"","PeriodicalId":19975,"journal":{"name":"Pakistan Journal of Zoology","volume":"57 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147878700","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effect of Quercetin on Cadmium-Induced PERK-CHOP Apoptosis Pathway in Rat Testis","authors":"Bingzhao Yan, Guiping Chen, Lulu Ding, Ruxue Huang, Wenjing Yu, Jicang Wang","doi":"10.17582/journal.pjz/20230912030836","DOIUrl":"https://doi.org/10.17582/journal.pjz/20230912030836","url":null,"abstract":"Water birds are considered to be important biological indicators for measuring the quality and significance of wetlands.We conducted field surveys at the six wetlands from each September to March 2017-2022.Data were collected using point count methods at one to fifteen vantage points in each sub-lake using binoculars, monocular, and Nikon D7200 (150-600 lens).A community-based survey including questionnaires and interviews with local hunters, shepherds, farmers, shopkeepers, and students at local schools, colleges, and universities.A total of 450 questionnaires were filled.Exclusively, 73 water birds from 11 orders were observed.Results showed the species composition of Charadriiformes exceptionally high (20 spp., 27.39%), while the lowest order was Accipitriformes (1 spp., 1.36%).Population trends for 73 water bird species, 16 (11.19%)birds species exhibited an increasing trend, 27 species (36.98%) declined, 6 species (8.21%) remained stable, while population trends for 24 species (32.87%) were unknown.13 species (17.8% of the total) have been listed as threatened species, including 8 species (10.95%) listed as near threatened, 2 species (2.73%) vulnerable, and 2 species (2.73%), while the remaining 61 (83.56%) species listed as least concern.Major threats for water birds were hunting, habitat loss, degradation, climate change, use of pesticides, pollution, human disturbance, trading, and agricultural development.Out of 73 species, 14 (56.16%) were pollution, 34 (46.57%) were human disturbance, 31 species (42.46%) were hunting, 30 species (41.09%) pollution, 22 species (30.13%) trading, 20 species of waterbirds are affected by pesticides (27.39%), 17 species (23.28%) climate change, 12 species (16.43%) agricultural development.The most hunted group is Anseriformes (43%), while the least is Suliformes (2%).The recommendation was suggested to conserve the water birds in the study area.","PeriodicalId":19975,"journal":{"name":"Pakistan Journal of Zoology","volume":"56 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147882026","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comparative Transcriptomic and Proteomic Analyses Provide Insights into the Key Genes Involved in Fat Deposition in Diqing Tibetan Pig","authors":"Jingru Nie","doi":"10.17582/journal.pjz/20230817034610","DOIUrl":"https://doi.org/10.17582/journal.pjz/20230817034610","url":null,"abstract":"","PeriodicalId":19975,"journal":{"name":"Pakistan Journal of Zoology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147904542","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Carvacrol Induces Doxorubicin-Resistant Breast Cancer Cell Apoptosis via Inhibition of the PI3K/Akt Pathway","authors":"Hu-Hu Chen, Jiao-han Zhou, Siat Yee Fong","doi":"10.17582/journal.pjz/20220421100442","DOIUrl":"https://doi.org/10.17582/journal.pjz/20220421100442","url":null,"abstract":"Key wordsOral squamous cell carcinoma, Snail/ Slug, YAP Oral squamous cell carcinoma (OSCC) is the most common malignancy of the oral cavity.Currently, no specific treatment is utilized to prevent the progression of OSCC.This study aimed to clarify whether Snail/Slug promoted OSCC cell proliferation by regulating yes-associated protein 1 (YAP).In this cell culture study, an OSCC cell model was constructed, followed by transfection with Snail-inhibitor.The OSCC HSC-3 cells were treated, and their apoptosis and viability were evaluated.Finally, Western blot, flow cytometry assay, Transwell assay, and scratch assay were used to explore the molecular mechanisms by which Snail/Slug promoted OSCC cell proliferation by regulating YAP.The activation of the Snail/ Slug pathway promoted the progression of OSCC.The Snail/Slug regulated the OSCC process via targeting YAP.Inhibition of the Snail/Slug pathway, however, reversed the effect of YAP on OSCC.These findings suggest that the Snail/Slug pathway promoted OSCC progression by targeting YAP.","PeriodicalId":19975,"journal":{"name":"Pakistan Journal of Zoology","volume":"56 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147891504","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abrar Ul Haq, Shusheng Yin, Amara Maryam, Muhammad Noman Khan, Hafiz Abdullah Shakir, Muhammad Akhtar Ali, Muhammad Irfan, Muhammad Faisal Maqbool, Yongming Li
{"title":"Lathyrol Binds with STAT3 DNA Binding Domain and Induces Apoptosis in Multiple Human Cancer Cells","authors":"Abrar Ul Haq, Shusheng Yin, Amara Maryam, Muhammad Noman Khan, Hafiz Abdullah Shakir, Muhammad Akhtar Ali, Muhammad Irfan, Muhammad Faisal Maqbool, Yongming Li","doi":"10.17582/journal.pjz/20230526090501","DOIUrl":"https://doi.org/10.17582/journal.pjz/20230526090501","url":null,"abstract":"","PeriodicalId":19975,"journal":{"name":"Pakistan Journal of Zoology","volume":"56 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147920577","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"An Experimental Study of Acupuncture to Rat Model of Obesity: Involvement of SIRT1 Signaling Pathway","authors":"Muzhi Pan, Pengli Si, Ping Zheng, Bingwei Ai","doi":"10.17582/journal.pjz/20231122060150","DOIUrl":"https://doi.org/10.17582/journal.pjz/20231122060150","url":null,"abstract":"","PeriodicalId":19975,"journal":{"name":"Pakistan Journal of Zoology","volume":"56 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147888733","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Suanyuan Zhang, Qing Ji, Xinglong Wu, Jinjing Wang, Jin Yao, Chengfang Li, Xiaorong Yang, Na Tan, Jing Yang, Hong Zheng
{"title":"Ginsenoside Rh2 Reduces Inflammation of Ulcerative Colitis via Elevating microRNA-30a-5p","authors":"Suanyuan Zhang, Qing Ji, Xinglong Wu, Jinjing Wang, Jin Yao, Chengfang Li, Xiaorong Yang, Na Tan, Jing Yang, Hong Zheng","doi":"10.17582/journal.pjz/20220217080248","DOIUrl":"https://doi.org/10.17582/journal.pjz/20220217080248","url":null,"abstract":"Malaria is a big challenge in endemic areas, especially in developing countries throughout the world.Rapidly changing climatic conditions have brought about a major shift in the prevalence and spread of vector-borne diseases.Khyber Pakhtunkhwa province is known for seasonal outbreaks of malaria and shares borders with several malaria-endemic countries.The phylogeny of Plasmodium vivax is limited and poorly explored in this region.Therefore, this study was designed to address the limitation of the poorly explored phylogeny of P. vivax in three districts of Khyber Pakhtunkhwa.Blood samples were collected for seven months in 2018 from individuals who visited the district headquarters (DHQ) hospitals.The samples were successfully amplified with a band size of 945 bp for the merozoite surface protein-1 (pvmsp-1) gene.The phylogenetic analysis grouped P. vivax into two major clades with different subclades in each clade.The retrieved sequences from other countries were distributed in the subclades.The first clade was split up further into three subclades comprising isolates from China, India, Turkey, Azerbaijan, Iran, Myanmar, Afghanistan, South Korea, New Papua Guinea, and Pakistan.The second clade was comprised of isolates from D. I. Khan, Peshawar, and Kohat of Pakistan, Turkey, Bangladesh, Thailand, Korea, the UK, Australia, and Sal-I and Belem of Brazil.The phylogenetics of P. vivax represented a close relationship with the P. vivax population of Turkey, Bangladesh, Thailand, and Korea among others, suggesting a possible introduction of distinct variants in Khyber Pakhtunkhwa.Further studies with larger datasets and broader geographical settings should be carried out to better understand the phylogeny of P. vivax.","PeriodicalId":19975,"journal":{"name":"Pakistan Journal of Zoology","volume":"56 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147900476","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effect of a Tibetan Medicine Rinqingchangjue on Gastric Hypomotility in Rats","authors":"NorBu Zhan-Dui","doi":"10.17582/journal.pjz/20230908085346","DOIUrl":"https://doi.org/10.17582/journal.pjz/20230908085346","url":null,"abstract":"conducted statistical analysis, and drafted the manuscript.HX, NZ, HR, D Dongzhi and D Drolma designed experiments.HX and NZ executed experiments.HR, D Dongzhi and D","PeriodicalId":19975,"journal":{"name":"Pakistan Journal of Zoology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147884399","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}