Pain PracticePub Date : 2024-07-01Epub Date: 2024-03-26DOI: 10.1111/papr.13368
Taif Mukhdomi, Bennett Andrassy, Junaid Mukhdomi
{"title":"Intrathecal drug delivery systems for cancer pain: Considerations for device type and indication.","authors":"Taif Mukhdomi, Bennett Andrassy, Junaid Mukhdomi","doi":"10.1111/papr.13368","DOIUrl":"10.1111/papr.13368","url":null,"abstract":"","PeriodicalId":19974,"journal":{"name":"Pain Practice","volume":" ","pages":"873-874"},"PeriodicalIF":2.5,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140288753","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pain PracticePub Date : 2024-07-01Epub Date: 2024-03-09DOI: 10.1111/papr.13361
I-Wen Chen, Chia-Li Kao, Kuo-Chuan Hung
{"title":"Comment on \"Pregabalin in patients with post-traumatic peripheral neuropathic pain: A meta-analysis of randomized controlled trials\".","authors":"I-Wen Chen, Chia-Li Kao, Kuo-Chuan Hung","doi":"10.1111/papr.13361","DOIUrl":"10.1111/papr.13361","url":null,"abstract":"","PeriodicalId":19974,"journal":{"name":"Pain Practice","volume":" ","pages":"869-870"},"PeriodicalIF":2.5,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140065667","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pain PracticePub Date : 2024-06-01Epub Date: 2024-01-22DOI: 10.1111/papr.13346
Heiko Pohl, Maria Susanne Neumeier, Martin Hänsel, Susanne Wegener
{"title":"The prevalence of head and face pain decreased from 1997 to 2017 in Switzerland.","authors":"Heiko Pohl, Maria Susanne Neumeier, Martin Hänsel, Susanne Wegener","doi":"10.1111/papr.13346","DOIUrl":"10.1111/papr.13346","url":null,"abstract":"<p><strong>Background: </strong>Pain in the head and the face is highly prevalent but may have changed during the past years. This study aimed to analyze changes in the prevalence of pain in the head and the face in Switzerland from 1997 to 2017.</p><p><strong>Methods: </strong>This is a secondary analysis of data collected in the Swiss Health Surveys of 1997-2017. Included persons were 15 years and older. Besides studying demographic data, we analyze the item assessing the presence of \"headache, pressure in the head, or facial pain\" during the past 4 weeks. Percentages with their Wilson confidence intervals are reported for each response option of categorical variables. Moreover, we calculate the age-standardized number of persons affected by the pain.</p><p><strong>Results: </strong>While 41% reported head and face pain in 1997, the proportion dropped to 31% in 2017. There was a decrease of 19.5% in women and 29.4% in men; after age standardization, the decrease was 16.5% in women and 25.4% in men. The most considerable numerical changes in the percentages of women with pain occurred in those aged 55-69 and 85 and above. In men, the changes were not limited to specific age groups.</p><p><strong>Conclusions: </strong>The proportion of people reporting headaches, pressure in the head, or facial pain has dropped in Switzerland from 1997 to 2017. However, in women, the prevalence diminished more strongly and consistently in the middle-aged and the elderly than in the young.</p>","PeriodicalId":19974,"journal":{"name":"Pain Practice","volume":" ","pages":"709-716"},"PeriodicalIF":2.6,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139513427","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pain PracticePub Date : 2024-06-01Epub Date: 2024-01-22DOI: 10.1111/papr.13350
Mario Fajardo Pérez, Ece Yamak-Altinpulluk, Rodrigo Díez Tafur, Carlos H Salazar-Zamorano, Karla Espinosa Morales, Pablo Oliver-Fornies, Andrés Rocha-Romero, Ricardo Aguilar Ureña, Angel Juarez-Lemus, Felice Galluccio, Alaa Abd-Elsayed
{"title":"Novel ultrasound-guided supraclavicular stellate ganglion block.","authors":"Mario Fajardo Pérez, Ece Yamak-Altinpulluk, Rodrigo Díez Tafur, Carlos H Salazar-Zamorano, Karla Espinosa Morales, Pablo Oliver-Fornies, Andrés Rocha-Romero, Ricardo Aguilar Ureña, Angel Juarez-Lemus, Felice Galluccio, Alaa Abd-Elsayed","doi":"10.1111/papr.13350","DOIUrl":"10.1111/papr.13350","url":null,"abstract":"<p><strong>Introduction: </strong>Stellate ganglion block (SGB) provides diagnostic and therapeutic benefits in pain syndromes in the head, neck, and upper extremity, including complex regional pain syndrome Types I and II, Raynaud's disease, hyperhidrosis, arterial embolism in the region of the arm.</p><p><strong>Methods: </strong>We present a novel ultrasound-guided supraclavicular stellate ganglion block. Considering the existing anatomical structures of the targeted area.</p><p><strong>Results and conclusions: </strong>We hope that we can provide fewer complications and additional benefits with this new approach.</p>","PeriodicalId":19974,"journal":{"name":"Pain Practice","volume":" ","pages":"808-814"},"PeriodicalIF":2.6,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139513424","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pain PracticePub Date : 2024-06-01Epub Date: 2024-01-18DOI: 10.1111/papr.13349
Alaa Abd-Elsayed, Robert Moghim, Noora Reffat
{"title":"Dorsal root ganglion stimulation (DRG-s) for potential resolution of restless leg syndrome symptoms and increased cost savings for patients: A case study.","authors":"Alaa Abd-Elsayed, Robert Moghim, Noora Reffat","doi":"10.1111/papr.13349","DOIUrl":"10.1111/papr.13349","url":null,"abstract":"<p><strong>Introduction: </strong>We report successful use of dorsal root ganglion stimulation (DRG-s) to treat a patient with persistent symptoms of restless leg syndrome (RLS).</p><p><strong>Methods: </strong>The treatment involved the placement of a small device millimeters away from the patient's DRG, which are nerves near the spinal cord that carry sensory information from the periphery of the body to the brain. The device automatically delivers electrical impulse to the DRG to alter and decrease pain perception in the brain.</p><p><strong>Results: </strong>Our case report elucidates the use of this procedure as a targeted therapy for RLS, with a nearly 90% reduction in reported symptoms in our patient, thus potentially reducing morbidity associated with this condition. Furthermore, we report a 10-year cost savings of nearly $90,000 following DRG-s for our patient.</p><p><strong>Conclusion: </strong>This case study aims to demonstrate the effectiveness of DRG-s neuromodulation in managing RLS, a condition that is often difficult and costly to treat.</p>","PeriodicalId":19974,"journal":{"name":"Pain Practice","volume":" ","pages":"805-807"},"PeriodicalIF":2.6,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139491868","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pain PracticePub Date : 2024-06-01Epub Date: 2024-02-13DOI: 10.1111/papr.13353
Inaeh de Paula Oliveira, Victória Regina da Silva Oliveira, Heloísa Alonso-Matielo, Beatriz Magalhães Eng, Daniel Ciampi de Andrade, Manoel Jacobsen Teixeira, Milena Cristina Dias Calsaverini, Fernando de Quadros Ribeiro, José Deney Alves Araújo, Helder Takashi Imoto Nakaya, José Pinhata Otoch, Camila Squarzoni Dale
{"title":"Phenotypical characterization of exteroceptive sensation and pain symptoms on diabetic patients.","authors":"Inaeh de Paula Oliveira, Victória Regina da Silva Oliveira, Heloísa Alonso-Matielo, Beatriz Magalhães Eng, Daniel Ciampi de Andrade, Manoel Jacobsen Teixeira, Milena Cristina Dias Calsaverini, Fernando de Quadros Ribeiro, José Deney Alves Araújo, Helder Takashi Imoto Nakaya, José Pinhata Otoch, Camila Squarzoni Dale","doi":"10.1111/papr.13353","DOIUrl":"10.1111/papr.13353","url":null,"abstract":"<p><strong>Backgroud: </strong>Diabetic neuropathy (DN) is one of the most common complications of diabetes, affecting about half of individuals with the disease. Among the various symptoms of DN, the development of chronic pain stands out and manifests as exacerbated responses to sensorial stimuli. The conventional clinical treatments used for general neuropathy and associated painful symptoms, still brings uncomplete and unsatisfactory pain relief. Patients with neuropathic pain syndromes are heterogeneous. They present with a variety of sensory symptoms and pain qualities which difficult the correct diagnosis of sensory comorbidities and consequently, the appropriate chronic pain management.</p><p><strong>Aims: </strong>Herein, we aimed to demonstrate the existence of different sensory profiles on diabetic patients by investigating epidemiological and clinical data on the symptomatology of a group of patients with DN.</p><p><strong>Methods: </strong>This is a longitudinal and observational study, with a sample of 57 volunteers diagnosed with diabetes from outpatient day clinic of Hospital Universitário of the University of São Paulo-Brazil. After being invited and signed the Informed Consent Form (ICF), patients were submitted to clinical evaluation and filled out pain and quality of life questionnaires. They also performed quantitative sensory test (QST) and underwent skin biopsy for correlation with cutaneous neuropathology.</p><p><strong>Results: </strong>Data demonstrate that 70% of the studied sample presented some type of pain, manifesting in a neuropathic or nociceptive way, what has a negative impact on the life of patients with DM. We also demonstrated a positive association between pain and anxiety and depression, in addition to pain catastrophic thoughts. Three distinct profiles were identified in the sample, separated according to the symptoms of pain: (i) subjects without pain; (ii) with mild or moderate pain; (iii) subjects with severe pain. We also identified through skin biopsy that diabetic patients presented advanced sensory impairment, as a consequence of the degeneration of the myelinated and unmyelinated peripheral fibers. This study characterized the painful symptoms and exteroceptive sensation profile in these diabetic patients, associated to a considerable level of sensory degeneration, indicating, and reinforcing the importance of the long-term clinical monitoring of individuals diagnosed with DM, regarding their symptom profiles and exteroceptive sensitivity.</p>","PeriodicalId":19974,"journal":{"name":"Pain Practice","volume":" ","pages":"724-738"},"PeriodicalIF":2.5,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139723548","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pain PracticePub Date : 2024-06-01Epub Date: 2024-01-24DOI: 10.1111/papr.13347
Obiyo Osuchukwu, James Gagnon, Janelle Richard, Wendy Craig, Aurora Quaye
{"title":"Liposomal bupivacaine in transversus abdominis plane blocks for lower abdominal surgery.","authors":"Obiyo Osuchukwu, James Gagnon, Janelle Richard, Wendy Craig, Aurora Quaye","doi":"10.1111/papr.13347","DOIUrl":"10.1111/papr.13347","url":null,"abstract":"<p><strong>Background: </strong>Transversus abdominis plane blocks are an established method of postoperative analgesia for abdominopelvic surgeries. Liposomal bupivacaine is an extended-release formulation of bupivacaine providing up to 72 h of analgesia. This study aims to determine if transversus abdominis plane blocks performed with liposomal bupivacaine are associated with reduced opioid consumption and level of pain intensity compared to conventional bupivacaine in patients undergoing lower abdominal surgery.</p><p><strong>Methods: </strong>This retrospective cohort study was conducted at a single institution between December 2020 and December 2021. After institutional review board approval, we identified patients who underwent lower abdominopelvic surgery with transversus abdominis plane blocks done with liposomal or conventional bupivacaine and collected demographic, clinical, and procedural information for analysis. We compared total opioid consumption over 72-h postoperatively in milligram morphine equivalents (MME), frequency of opioid utilization, and average level of pain intensity between groups. These outcomes were also evaluated after adjusting for covariates. Data were presented as mean ± SD, median [IQR] or frequency (%), as appropriate; p < 0.05 was accepted as significant.</p><p><strong>Results: </strong>A total of 178 patients met inclusion criteria, with 79 patients receiving an admixture of liposomal bupivacaine and conventional bupivacaine and 99 patients receiving conventional bupivacaine. The liposomal bupivacaine group had a median opioid consumption 72-h postoperatively of 47.5 [18-91.8] MME compared to 88 [43.8-160] MME in the conventional bupivacaine group, p = 0.045. Differences in opioid consumption between the groups did not reach statistical significance after adjustment for demographic and clinical characteristics, p = 0.11. There was no significant difference in frequency of opioid use or average pain intensity.</p><p><strong>Conclusion: </strong>Transversus abdominis plane blocks using an admixture of liposomal bupivacaine conventional bupivacaine are not associated with decreased opioid consumption or reduced pain up to 72 h following elective abdominopelvic surgery.</p>","PeriodicalId":19974,"journal":{"name":"Pain Practice","volume":" ","pages":"717-723"},"PeriodicalIF":2.6,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11178472/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139542868","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pain PracticePub Date : 2024-06-01Epub Date: 2024-01-31DOI: 10.1111/papr.13351
Soyoon Park, Ji-Hoon Park, Jae Ni Jang, Su-Il Choi, Yumin Song, Young Uk Kim, Sukhee Park
{"title":"Pulsed radiofrequency of lumbar dorsal root ganglion for lumbar radicular pain: A systematic review and meta-analysis.","authors":"Soyoon Park, Ji-Hoon Park, Jae Ni Jang, Su-Il Choi, Yumin Song, Young Uk Kim, Sukhee Park","doi":"10.1111/papr.13351","DOIUrl":"10.1111/papr.13351","url":null,"abstract":"<p><strong>Background: </strong>Pulsed radiofrequency (PRF) of the lumbar dorsal root ganglion (DRG) has been widely used as a method to relieve lumbar radicular pain (LRP). However, the value of PRF application in LRP patients remains uncertain. This systematic review aimed to compare the effects of PRF of lumbar DRG and LEI in patients with LRP.</p><p><strong>Methods: </strong>A literature search was performed using well-known databases for articles published up to May 2023. We included randomized controlled trials (RCTs) that evaluated the effects of PRF compared to LEI with or without steroids. We screened articles, extracted data, and assessed risk of bias in duplicate. The pain scores and Oswestry Disability Index (ODI) scores at 1, 3, and 6 months after procedures were obtained. A random-effects meta-analysis model was applied for outcomes. We evaluated evidence certainty for each outcome using the GRADE scoring system. This review was registered in the PROSPERO (ID: CRD42021253628).</p><p><strong>Results: </strong>A total of 10 RCTs were included and data of 613 patients were retrieved. We assessed the overall quality of the evidence as very low to moderate. PRF showed no difference in pain scores at 1 (mean difference [MD] -0.80, 95% confidence interval [CI] -1.59 to 0.00, low certainty) and 6 months (MD -2.37, 95% CI -4.79 to 0.05, very low certainty), and significantly improved pain scores at 3 months (MD -1.31, 95% CI -2.29 to -0.33, low certainty). There was no significant difference in ODI score at any interval (very low to low certainty). In the subgroup who underwent a diagnostic block, did not use steroids, and PRF duration greater than 360 s, PRF significantly reduced pain scores at 3 months after procedures.</p><p><strong>Conclusions: </strong>We found low quality of the evidence supporting adjuvant PRF to the lumbar DRG has a greater analgesic effect at 3 months after procedures in patients with LRP than LEI. We identified no convincing evidence to show that this treatment improves function. High-quality evidence is lacking, and data were largely derived from short-term effects. Given these limitations, high-quality trials with data on long-term effects are needed.</p>","PeriodicalId":19974,"journal":{"name":"Pain Practice","volume":" ","pages":"772-785"},"PeriodicalIF":2.6,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139642689","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}