Particle & Particle Systems Characterization最新文献

Theranostic Nanoparticles for Fluorosensitive Visualization and Inhibition of Amyloid Beta-Induced Neuroinflammation. 用于淀粉样蛋白诱导的神经炎症的荧光敏感可视化和抑制的治疗纳米颗粒。

IF 2.7 4区材料科学

Particle & Particle Systems Characterization Pub Date : 2026-02-01 Epub Date: 2026-02-19 DOI: 10.1002/ppsc.202500220

Umme Tamima, Hoda M Gebril, Md Ragib Hasan, Miguel A Quintero, Aravind Aryasomayajula, Diya Chengappa, Imran Attarwala, Bradley L Truong, Prabhas V Moghe, Kathryn E Uhrich

{"title":"Theranostic Nanoparticles for Fluorosensitive Visualization and Inhibition of Amyloid Beta-Induced Neuroinflammation.","authors":"Umme Tamima, Hoda M Gebril, Md Ragib Hasan, Miguel A Quintero, Aravind Aryasomayajula, Diya Chengappa, Imran Attarwala, Bradley L Truong, Prabhas V Moghe, Kathryn E Uhrich","doi":"10.1002/ppsc.202500220","DOIUrl":"10.1002/ppsc.202500220","url":null,"abstract":"<p><p>The emerging field of microglial therapies has significant potential to alleviate fibrillar amyloid beta (fAβ)-associated neuroinflammation, which exacerbates neurodegeneration in Alzheimer's disease (AD). New therapeutic strategies integrate with diagnostic capabilities to robustly elucidate the mechanisms and consequences of intervention. Amphiphilic macromolecules (AMs), comprising a hydrophilic sugar backbone, hydrophobic aliphatic side chains, and poly(ethylene glycol) (PEG) segments for enhanced stability, exhibit significant potential for biomedical applications due to their biocompatibility and self-assembled nanoscale structures. This study presents rhodamine B-tagged (Rh) AMs (Rh-AMs) that create stable nanoparticles (Rh-AM-NPs) with potential neurotherapeutic and diagnostic applications. Rh-AMs were successfully synthesized and validated using NMR, FTIR, UV-vis, and fluorescent spectroscopy. The ratio of labeled to unlabeled AMs necessary for Rh-AM-NPs formation was optimized via flash nanoprecipitation to confirm the minimum quantity required for direct visualization within cells. Using an in vitro BV2 microglial model, we demonstrated that Rh-AM-NPs exhibit multifunctional properties, suppressing the microglial inflammatory response and reducing microglial uptake of fAβ within a low-toxicity range, while simultaneously enabling in situ tracking of cellular interactions. This work validates a novel nanoplatform for combined AD therapy and diagnostics.</p>","PeriodicalId":19903,"journal":{"name":"Particle & Particle Systems Characterization","volume":"43 2","pages":"e00220"},"PeriodicalIF":2.7,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13173615/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147964411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Gold Nanorods Coated with Palladium‐Platinum Alloy Shell Superstructures for Enhanced Plasmon‐Driven Photocatalysis 包覆钯-铂合金外壳超结构的金纳米棒用于增强等离子体驱动光催化

4区材料科学

Particle & Particle Systems Characterization Pub Date : 2025-11-26 DOI: 10.1002/ppsc.202500121

Zhen‐Ming Shen, Jie Liu, Qi Zhang, Er‐Ji Zhang, Xiaoyu Zhao, Yiqiang Gao, Zhigang Zhou, Tian‐Song Deng

{"title":"Gold Nanorods Coated with Palladium‐Platinum Alloy Shell Superstructures for Enhanced Plasmon‐Driven Photocatalysis","authors":"Zhen‐Ming Shen, Jie Liu, Qi Zhang, Er‐Ji Zhang, Xiaoyu Zhao, Yiqiang Gao, Zhigang Zhou, Tian‐Song Deng","doi":"10.1002/ppsc.202500121","DOIUrl":"https://doi.org/10.1002/ppsc.202500121","url":null,"abstract":"ABSTRACT Bimetallic and trimetallic nanostructures offer unique physicochemical properties for enhancing photocatalytic performance. In this work, a facile and reproducible method of preparing palladium‐platinum (PdPt) alloy shell on gold nanorods (AuNRs) is designed for enhancing the catalytic reactions under light irradiation. Specifically, Pd and Pt shells are sequentially deposited on the surface of AuNRs, forming well‐defined core‐shell Au@PdPt superstructures (Au@PdPt SSs). Photocatalytic activity is evaluated through the NaBH 4 ‐mediated reduction of methyl blue (MB), demonstrating that Au@PdPt SSs exhibit significantly enhanced photocatalytic performance under light irradiation compared to bimetallic counterparts or single‐component analogs. Finite‐difference time‐domain simulations reveal that the spatial distribution of the enhanced electric field closely correlates with the structural characteristics of the Au@PdPt SSs, confirming the influence of morphology on plasmonic behavior. The localized surface plasmon resonance (LSPR) of Au promotes hot electron generation and transfer to the catalytic PdPt alloy shell surface. The results highlight the synergistic interaction between plasmonic Au core and catalytic PdPt shells, where plasmon‐induced charge separation and migration play a pivotal role. This work provides a rational design strategy for constructing high‐efficiency plasmon‐mediated photocatalysts based on multi‐metallic nanostructures, with potential applications in green chemistry and environmental remediation.","PeriodicalId":19903,"journal":{"name":"Particle & Particle Systems Characterization","volume":"43 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147897071","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Preparation and Regulation of a Platinum Nanoparticle Embedded Titanium Dioxide Material 纳米铂包埋二氧化钛材料的制备与调控

4区材料科学

Particle & Particle Systems Characterization Pub Date : 2025-11-14 DOI: 10.1002/ppsc.202500170

Mingjun Xiao, Huizhen Sun, Hong Zhang, Haibin Tang

引用次数: 0

Synthesis of Gold Nanorod@AuAg Hollow Shell Nanostructures with Enhanced Refractive Index Sensitivity and SERS Activity 具有增强折射率灵敏度和SERS活性的金Nanorod@AuAg空心壳纳米结构的合成

4区材料科学

Particle & Particle Systems Characterization Pub Date : 2025-08-28 DOI: 10.1002/ppsc.202500110

Zexiang Shen, Jie Liu, Kun‐Peng Wang, Xuefeng Zhang, Lan Chen, Zhigang Zhou, Tian‐Song Deng

{"title":"Synthesis of Gold Nanorod@AuAg Hollow Shell Nanostructures with Enhanced Refractive Index Sensitivity and SERS Activity","authors":"Zexiang Shen, Jie Liu, Kun‐Peng Wang, Xuefeng Zhang, Lan Chen, Zhigang Zhou, Tian‐Song Deng","doi":"10.1002/ppsc.202500110","DOIUrl":"https://doi.org/10.1002/ppsc.202500110","url":null,"abstract":"Abstract Hollow core‐shell noble metallic nanoparticles have garnered significant attention due to their plasmonic properties, which are markedly enhanced by the hollow structure. However, precisely controlling the size and shape of the shell and cavity in such structures remains a challenge. Here, a novel strategy is reported that eliminates the need for etchants, utilizing monodispersed gold nanorods (AuNRs) as templates to synthesize hollow Au@AuAg core‐shell nanostructures. By precisely regulating the CTAB/CTAC and Au/Ag ratios during the co‐deposition of Au and Ag atoms onto the AuNRs, uniform bimetallic hollow shells are achieved without the use of corrosive etching agents. High‐resolution TEM and EDS characterizations confirm the formation of crystalline AuAg alloy shells surrounding the AuNRs cores, with well‐defined cavities. Compared to pure silver shells, the AuAg alloy shells exhibit superior stability. Furthermore, the resulting Au@AuAg nanostructures with hollow shells demonstrate significantly enhanced refractive index sensitivity and surface‐enhanced Raman scattering (SERS) activity relative to pristine AuNRs, making them highly promising for biomedical applications such as biosensing and bioimaging.","PeriodicalId":19903,"journal":{"name":"Particle & Particle Systems Characterization","volume":"42 12","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147332243","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Oxygen Defects Enriched Cerium Oxide Nanozyme for Sensitive Colorimetric Detection of Tannic Acid 氧缺陷富集氧化铈纳米酶灵敏比色法检测单宁酸

4区材料科学

Particle & Particle Systems Characterization Pub Date : 2025-02-21 DOI: 10.1002/ppsc.202400249

Xuke Fan, Haifeng Yu, M. -X. Zhang, Zitong Zhou, Yanling Yang, Yijun Pang

{"title":"Oxygen Defects Enriched Cerium Oxide Nanozyme for Sensitive Colorimetric Detection of Tannic Acid","authors":"Xuke Fan, Haifeng Yu, M. -X. Zhang, Zitong Zhou, Yanling Yang, Yijun Pang","doi":"10.1002/ppsc.202400249","DOIUrl":"https://doi.org/10.1002/ppsc.202400249","url":null,"abstract":"Abstract Although the application of nanozymes is widely studied, it is still a huge challenge to develop a facile strategy to improve enzyme activity. Herein, a novel nanozyme construction strategy is proposed that involves the modulation of surface defects on CeO 2 through controlled atmosphere under mild condition. The CeO 2 prepared in this study is subjected to thermal treatment under various atmospheres, such as H 2 ‐Ar and air, resulting in the formation of tunable oxygen vacancies, as confirmed by high‐resolution transmission electron microscopy (HRTEM), X‐ray photoelectron spectroscopy (XPS), X‐ray diffraction (XRD), and UV–vis spectroscopy characterizations. The Cb‐H demonstrates peroxidase‐mimicking activity and achieves excellent catalytic performance due to the advantageous nanozyme preparation process, which results in the highest fraction of oxygen vacancies. Therefore, a colorimetric sensor is constructed for the fast and sensitive quantitative analysis of TA with good linearity in the range of 0–2.5 µ m . This work offers strategies for optimizing the catalytic activity of defect‐engineered nanozymes and highlights the practical potential of Cb‐H in the colorimetric detection of tannic acid (TA).","PeriodicalId":19903,"journal":{"name":"Particle & Particle Systems Characterization","volume":"42 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/ppsc.202400249","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147917524","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

One‐Pot Polyol Syntheses of Ag Right Bipyramids and Nanocubes, and their Surface‐Enhanced Raman Scattering Properties 银右双锥体和纳米立方的一锅多元醇合成及其表面增强拉曼散射性能

4区材料科学

Particle & Particle Systems Characterization Pub Date : 2024-11-21 DOI: 10.1002/ppsc.202400211

Zhaoxi Zhu, Xiaolu Wang, Dan Li, Chung‐Jen Ou, Ruochen Liu, Taifeng Lin, Fu Guo

{"title":"One‐Pot Polyol Syntheses of Ag Right Bipyramids and Nanocubes, and their Surface‐Enhanced Raman Scattering Properties","authors":"Zhaoxi Zhu, Xiaolu Wang, Dan Li, Chung‐Jen Ou, Ruochen Liu, Taifeng Lin, Fu Guo","doi":"10.1002/ppsc.202400211","DOIUrl":"https://doi.org/10.1002/ppsc.202400211","url":null,"abstract":"Abstract Camphorquinone (CQ)‐mediated one‐pot polyol methods are developed to synthesize silver right bipyramids and nanocubes. Morphology control between silver right bipyramids and nanocubes is conducted by adjusting FeCl 3 concentration. Silver right bipyramids with an average size of 170 nm and a yield of 87% are obtained with 0.11 m m FeCl 3 , while silver nanocubes with an average size of 120 nm and a yield of 70% are obtained with 0.04 m m FeCl 3 . The as‐synthesized Ag right bipyramids and nanocubes fabricate Surface‐enhanced Raman scattering (SERS) substrates with good signal reproducibility to detect the Rhodamine 6G with concentrations down to 10 −12 m . The SERS performance of silver right bipyramids larger than 100 nm is experimentally investigated. A comparison of the Raman enhancement effect between Ag right bipyramid and nanocube is conducted by comparing the enhancement factors of as‐fabricated Ag right bipyramid and nanocube SERS substrates. The Ag right bipyramid and nanocube SERS substrates are obtained at the same experimental condition, and their enhancement factors are calculated to be 3.11 × 10 4 and 2.37 × 10 4 , respectively. The fabricated sensitive SERS substrates can potentially be used for ultrasensitive detection of analytes in applications such as food safety and environmental monitoring.","PeriodicalId":19903,"journal":{"name":"Particle & Particle Systems Characterization","volume":"42 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147880369","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Morphology Regulation of Organophosphate Crystals by Micro‐Jetting Technique 微喷射技术对有机磷酸酯晶体形态的调控

4区材料科学

Particle & Particle Systems Characterization Pub Date : 2024-09-30 DOI: 10.1002/ppsc.202400173

Qian Yang, Wenbo Yang, Zhaoyan Guo, Yumeng Zhou, Yue Ru, Guicun Qi, Dali Gao, Shengyang Tao

{"title":"Morphology Regulation of Organophosphate Crystals by Micro‐Jetting Technique","authors":"Qian Yang, Wenbo Yang, Zhaoyan Guo, Yumeng Zhou, Yue Ru, Guicun Qi, Dali Gao, Shengyang Tao","doi":"10.1002/ppsc.202400173","DOIUrl":"https://doi.org/10.1002/ppsc.202400173","url":null,"abstract":"Abstract Organophosphates nucleating agents are widely used in the plastics industry. Nucleating agents with different morphologies have various effects on the resin materials. The micro‐jetting technique is shown to be a promising tool for the controlled preparation of micro‐and nano‐sized particles. Therefore, in this paper, controllable preparation of sodium 2,2'‐methylene‐bis‐(4,6‐di‐tert‐butylphenyl) phosphate (NA11) is achieved by the micro‐jetting technique. The study focused on the impact of various parameters on its shape and size. Hexagonal, rhombic, rod‐shaped, and needle‐shaped micro‐sized NA11 crystals are prepared. The results show that the decrease in the polarity of the organic solvents added in the antisolvent water led to the transformation of NA11 from bulk hexagon to plate‐like rhombus and finally to needle‐shaped crystals. The addition of surfactants can regulate the crystal growth rates and orientations, thereby facilitating the formation of rod‐shaped crystals. Based on rod‐shaped crystals, the crystal size is studied. Crystals with average particle sizes in the range of 40–100 µm can be obtained with coefficients of variation as low as 4% by varying the relevant experimental parameters such as the supersaturation, the solution homogeneity in the crystal growth environment, and the mixing intensity. This study provides references for designing functional materials.","PeriodicalId":19903,"journal":{"name":"Particle & Particle Systems Characterization","volume":"42 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147898126","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Seed‐Mediated Synthesis of Gold Nanobipyramids at Low CTAB Concentration Using Binary Surfactants 用二元表面活性剂在低CTAB浓度下种子介导合成金纳米金字塔

4区材料科学

Particle & Particle Systems Characterization Pub Date : 2024-09-25 DOI: 10.1002/ppsc.202400190

Er‐Ji Zhang, Tian‐Song Deng, Zhuo Chen, Liyong Liu, Guilin Wu, Yu‐Chun Cheng, Jia‐Fei Gao, Kun‐Peng Wang, Jie Liu

{"title":"Seed‐Mediated Synthesis of Gold Nanobipyramids at Low CTAB Concentration Using Binary Surfactants","authors":"Er‐Ji Zhang, Tian‐Song Deng, Zhuo Chen, Liyong Liu, Guilin Wu, Yu‐Chun Cheng, Jia‐Fei Gao, Kun‐Peng Wang, Jie Liu","doi":"10.1002/ppsc.202400190","DOIUrl":"https://doi.org/10.1002/ppsc.202400190","url":null,"abstract":"Abstract The conventional method for synthesizing gold nanobipyramids (AuNBPs) is well established. However, the cytotoxicity resulting from the conjugates between hexadecyltrimethylammonium bromide (CTAB) and gold limits their biomedical applications. This study introduces a dual surfactant approach with CTAB and sodium oleate (NaOL) in the seed‐mediated synthesis of the AuNBPs, which can significantly reduce the CTAB concentration to 10 m M . Additionally, optimal growth conditions are achieved by varying the volumes of seed solution, AgNO 3 , and HCl. Under low CTAB concentrations, AuNBPs with tunable sizes and localized surface plasmon resonances between 600 and 1200 nm are successfully synthesized, as characterized by UV–vis‐NIR spectroscopy, transmission electron microscopy (TEM), and finite‐difference time‐domain (FDTD) simulations. This work demonstrates a method for synthesizing AuNBPs at low CTAB concentrations using binary surfactants and provides a framework applicable to the synthesis of other metallic nanomaterials.","PeriodicalId":19903,"journal":{"name":"Particle & Particle Systems Characterization","volume":"41 11","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/ppsc.202400190","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147899407","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Titania Doped CDs as Effective CT‐DNA Binders: A Novel Fluorescent Probe via Green Synthesis 掺杂二氧化钛的 CD 作为有效的 CT-DNA 粘合剂：通过绿色合成的新型荧光探针

IF 2.7 4区材料科学

Particle & Particle Systems Characterization Pub Date : 2024-09-10 DOI: 10.1002/ppsc.202400127

Namrata W. N, Neethu Joseph, Nikita Varghese, Meera Varghese, Sreehari K. S, Francis Joy, Yamuna Nair, Manoj B

{"title":"Titania Doped CDs as Effective CT‐DNA Binders: A Novel Fluorescent Probe via Green Synthesis","authors":"Namrata W. N, Neethu Joseph, Nikita Varghese, Meera Varghese, Sreehari K. S, Francis Joy, Yamuna Nair, Manoj B","doi":"10.1002/ppsc.202400127","DOIUrl":"https://doi.org/10.1002/ppsc.202400127","url":null,"abstract":"Carbon dots (CDs), which belong to the class of zero‐dimensional carbon‐based nanomaterials, have garnered significant interest owing to their wide array of applications spanning from the electronics industry to the healthcare sector. This work employs a facile, inexpensive approach to synthesize green luminescent carbon dots (J‐10) from a potential medicinal plant named Justicia Wynaadensis by the one‐step hydrothermal method. A nanocomposite (JT‐10) of the CDs is prepared by adding TiO2 nanoparticles derived from green synthesis of Lavandula leaves. The J‐10 and JT‐10 are further characterized by X‐ray Diffraction spectroscopy (XRD), Transmission Electron Microscopy (TEM), Raman analysis X‐ray Photoelectron Spectroscopy (XPS), and Fourier transform infrared techniques (FTIR), UV–vis spectroscopy, Photoluminescence (PL), and Fluorescence or PL lifetime analysis. The average size of synthesized CDs is 1.85 nm and exhibits an excitation‐dependent fluorescence nature at 320 nm. PL lifetime analysis of J‐10 and JT‐10 is calculated to be 5.80 and 2.84 ns respectively. Offering these unique optical properties and biocompatibility, the synthesised material is suitable for investigating their binding affinity and interaction mechanisms with DNA. The use of JT‐10 in DNA binding studies contributes to the development of sustainable and efficient nanomaterials for applications in biosensors, drug delivery, and gene therapy.","PeriodicalId":19903,"journal":{"name":"Particle & Particle Systems Characterization","volume":"20 1","pages":""},"PeriodicalIF":2.7,"publicationDate":"2024-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142223458","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Physical Crosslinking of Aqueous Polymer Dispersions: A Perspective 水性聚合物分散体的物理交联：透视

IF 2.7 4区材料科学

Particle & Particle Systems Characterization Pub Date : 2024-09-10 DOI: 10.1002/ppsc.202400103

Nicholas Ballard, Nerea Jimenez, José M. Asua

引用次数: 0