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Pharmazie in Unserer Zeit最新文献

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[Molecular copies of off-patent biologics that have become biosimilars: a new group recombinant products]. [已成为生物仿制药的非专利生物制剂的分子复制品:一组新的重组产品]。
Pharmazie in Unserer Zeit Pub Date : 2012-11-01 DOI: 10.1002/pauz.201200490
Theo Dingermann, Ilse Zündorf
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引用次数: 3
["Freedom to Operate". Patent Legal Aspects in the preparation of biosimilars]. “操作自由”。生物仿制药制备中的专利法律问题[j]。
Pharmazie in Unserer Zeit Pub Date : 2012-11-01 DOI: 10.1002/pauz.201200495
Andrea Sommer
{"title":"[\"Freedom to Operate\". Patent Legal Aspects in the preparation of biosimilars].","authors":"Andrea Sommer","doi":"10.1002/pauz.201200495","DOIUrl":"https://doi.org/10.1002/pauz.201200495","url":null,"abstract":"Biosimilars sind Nachfolgeprodukte biotechnologischer Arzneimittel (Biopharmazeutika), deren Patentschutz abgelaufen ist. In der EU-Gesetzgebung wurde der Begriff “einem biologischen Referenzarzneimittel ahnliches biologisches Arzneimittel” (Biosimilar) gepragt, da ein biopharmazeutisches Nachahmerpraparat nur ahnlich (similar), aber nicht identisch mit dem Originalpraparat sein kann.","PeriodicalId":19878,"journal":{"name":"Pharmazie in Unserer Zeit","volume":"41 6","pages":"481-4"},"PeriodicalIF":0.0,"publicationDate":"2012-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1002/pauz.201200495","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31198236","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Arzneimittel in der Palliativmedizin. Von Constanze Rémi und Thomas Hagen 镇定类药物从康Ré弥和托马斯•哈根
Pharmazie in Unserer Zeit Pub Date : 2012-11-01 DOI: 10.1002/PAUZ.201290112
Christian Redmann
{"title":"Arzneimittel in der Palliativmedizin. Von Constanze Rémi und Thomas Hagen","authors":"Christian Redmann","doi":"10.1002/PAUZ.201290112","DOIUrl":"https://doi.org/10.1002/PAUZ.201290112","url":null,"abstract":"","PeriodicalId":19878,"journal":{"name":"Pharmazie in Unserer Zeit","volume":"37 1","pages":"503-504"},"PeriodicalIF":0.0,"publicationDate":"2012-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81481748","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Coming soon: the pill for men?]. [即将推出:男性避孕药?]
Pharmazie in Unserer Zeit Pub Date : 2012-11-01 DOI: 10.1002/pauz.201290098
Ilse Zündorf, Theo Dingermann
{"title":"[Coming soon: the pill for men?].","authors":"Ilse Zündorf, Theo Dingermann","doi":"10.1002/pauz.201290098","DOIUrl":"https://doi.org/10.1002/pauz.201290098","url":null,"abstract":"","PeriodicalId":19878,"journal":{"name":"Pharmazie in Unserer Zeit","volume":"41 6","pages":"442-3"},"PeriodicalIF":0.0,"publicationDate":"2012-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1002/pauz.201290098","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31198228","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
35 Jahre Resistenzen gegen Antibiotika 35年的抗药性
Pharmazie in Unserer Zeit Pub Date : 2012-09-01 DOI: 10.1002/PAUZ.201290081
U. Holzgrabe
{"title":"35 Jahre Resistenzen gegen Antibiotika","authors":"U. Holzgrabe","doi":"10.1002/PAUZ.201290081","DOIUrl":"https://doi.org/10.1002/PAUZ.201290081","url":null,"abstract":"So titelte “Nature Reviews Microbiology” im Juni 2012. Anlass war eine Studie, die mittels Sequenzierung ganzer Genome belegen konnte, wie Resistenzen vom Menschen auf Tiere ubertragen werden konnen und umgekehrt.","PeriodicalId":19878,"journal":{"name":"Pharmazie in Unserer Zeit","volume":"57 1","pages":"374-375"},"PeriodicalIF":0.0,"publicationDate":"2012-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87051804","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Antikörper bei Hypercholesterinämie 这是高胆固醇的抗体
Pharmazie in Unserer Zeit Pub Date : 2012-09-01 DOI: 10.1002/PAUZ.201290083
David Brunn, Benjamin Kühn, Verena Schaub, Ramona Sitzler, I. Zündorf, T. Dingermann
{"title":"Antikörper bei Hypercholesterinämie","authors":"David Brunn, Benjamin Kühn, Verena Schaub, Ramona Sitzler, I. Zündorf, T. Dingermann","doi":"10.1002/PAUZ.201290083","DOIUrl":"https://doi.org/10.1002/PAUZ.201290083","url":null,"abstract":"Es mag etwas merkwurdig klingen, dass nun auch bei Hypercholesterinamie Antikorper zum Einsatz kommen sollen. Aber es gibt eben durchaus Patienten, deren Lipidspiegel mit der bisher verfugbaren Standardtherapie nicht ausreichend gesenkt werden konnen. Hier konnten eventuell Antikorper helfen.","PeriodicalId":19878,"journal":{"name":"Pharmazie in Unserer Zeit","volume":"6 1","pages":"376-377"},"PeriodicalIF":0.0,"publicationDate":"2012-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84790877","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Lys05 – ein neuer Ansatz zur Tumortherapie? Lys05——癌症治疗的新方法?
Pharmazie in Unserer Zeit Pub Date : 2012-09-01 DOI: 10.1002/PAUZ.201290082
Ines Schmidt, U. Holzgrabe
{"title":"Lys05 – ein neuer Ansatz zur Tumortherapie?","authors":"Ines Schmidt, U. Holzgrabe","doi":"10.1002/PAUZ.201290082","DOIUrl":"https://doi.org/10.1002/PAUZ.201290082","url":null,"abstract":"Auch wenn es in den letzten Jahrzehnten Fortschritte in der Tumortherapie gegeben hat, so fehlt es an innovativen Ansatzen. Die Arbeitsgruppe um R. K. Amaravadi an der University of Sciences, Philadelphia, USA, untersuchte Inhibitoren der Autophagie, durch deren Einsatz die bisherige Chemotherapie erganzt werden kann.","PeriodicalId":19878,"journal":{"name":"Pharmazie in Unserer Zeit","volume":"1 1","pages":"375-376"},"PeriodicalIF":0.0,"publicationDate":"2012-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82082454","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Tumortherapie mit SMAC-Mimetika? 用抗生素治疗?
Pharmazie in Unserer Zeit Pub Date : 2012-09-01 DOI: 10.1002/PAUZ.201290084
Sebastian Lobentanzer, T. Gebel, H. Kaminski, Tanja Lohnherr, Stephan Oksas, I. Zündorf, T. Dingermann
{"title":"Tumortherapie mit SMAC-Mimetika?","authors":"Sebastian Lobentanzer, T. Gebel, H. Kaminski, Tanja Lohnherr, Stephan Oksas, I. Zündorf, T. Dingermann","doi":"10.1002/PAUZ.201290084","DOIUrl":"https://doi.org/10.1002/PAUZ.201290084","url":null,"abstract":"TL32711, inzwischen unter dem Namen Birinapant von TetraLogic Pharmaceuticals entwickelt, konnte eine neue Klasse unspezifischer Zytostatika – die SMAC-Mimetika – begrunden. Es befindet sich momentan in klinischen Studien der Phase II als Monotherapeutikum und als Add-On bei soliden Tumoren und in Phase I/II als Monotherapeutikum bei akuter myeloischer Leukamie.","PeriodicalId":19878,"journal":{"name":"Pharmazie in Unserer Zeit","volume":"105 1","pages":"377-378"},"PeriodicalIF":0.0,"publicationDate":"2012-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72590303","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Schilddrüsenerkrankungen in der Schwangerschaft: Beratung in der Apotheke 怀孕甲状腺疾病药房的咨询
Pharmazie in Unserer Zeit Pub Date : 2012-09-01 DOI: 10.1002/PAUZ.201200488
Miriam Ude, Ramona Steri
{"title":"Schilddrüsenerkrankungen in der Schwangerschaft: Beratung in der Apotheke","authors":"Miriam Ude, Ramona Steri","doi":"10.1002/PAUZ.201200488","DOIUrl":"https://doi.org/10.1002/PAUZ.201200488","url":null,"abstract":"Eine Schilddrusenfehlfunktion kann negative Auswirkungen auf das ungeborene Kind haben. Fehlgeburten, Fruhgeburten oder Wachstumsretardierungen konnen die Folge sein. Es konnen sowohl Hypo- wie auch Hyperthyreosen auftreten. Wahrend der Schwangerschaft ist daher eine bestehende Schilddrusenerkrankung zu behandeln und engmaschig zu kontrollieren. Auch die Iodsupplementierung sollte in ausreichendem Mas erfolgen. In der Apotheke ist die Kenntnis der unterschiedlichen Schilddrusenproblematiken bei Kinderwunsch, in der Schwangerschaft sowie in der Stillzeit von immenser Bedeutung. Auch die jeweils einzusetzende Medikation mit moglichen Kontraindikationen und Wechselwirkungen muss fur eine adaquate Beratung der betroffenen Patientin beherrscht werden.","PeriodicalId":19878,"journal":{"name":"Pharmazie in Unserer Zeit","volume":"74 1","pages":"409-415"},"PeriodicalIF":0.0,"publicationDate":"2012-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83970997","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Die Ambrosie – Geschenk oder Fluch der Götter?
Pharmazie in Unserer Zeit Pub Date : 2012-09-01 DOI: 10.1002/PAUZ.201290090
T. Junghans
{"title":"Die Ambrosie – Geschenk oder Fluch der Götter?","authors":"T. Junghans","doi":"10.1002/PAUZ.201290090","DOIUrl":"https://doi.org/10.1002/PAUZ.201290090","url":null,"abstract":"","PeriodicalId":19878,"journal":{"name":"Pharmazie in Unserer Zeit","volume":"1 1","pages":"429-430"},"PeriodicalIF":0.0,"publicationDate":"2012-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72985318","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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