Pharmatherapeutica最新文献_第2页

Acute psychotic disorders treated with 5% zuclopenthixol acetate in 'Viscoleo' ('Cisordinol-Acutard'), a global assessment of the clinical effect: an open multi-centre study. 在“Viscoleo”(“Cisordinol-Acutard”)中使用5%醋酸zuclopenthixol治疗急性精神病，这是一项临床效果的全球评估:一项开放的多中心研究。

Pharmatherapeutica Pub Date : 1989-01-01

A C Løwert, E M Rasmussen, R Holm, F Almbjerg, H Calberg, A Joensen, M Nimb, H Baden, E Andersen, T Westergård

引用次数: 0

[Effectiveness and tolerance of amoxicillin/clavulanic acid ("Augmentin") in intravenous injections in adults]. [成人静脉注射阿莫西林/克拉维酸(Augmentin)的有效性和耐受性]。

Pharmatherapeutica Pub Date : 1989-01-01

K M el Filali, N el M'Daghri, H el Kabli, M Hajji, M Benbachir, H Himmich

引用次数: 0

Flupenthixol and fluvoxamine in mild to moderate depression: a comparison in general practice. 氟苯噻醇和氟伏沙明治疗轻至中度抑郁症的比较

Pharmatherapeutica Pub Date : 1989-01-01

B A Hamilton, P G Jones, A N Hoda, P M Keane, I Majid, S I Zaidi

引用次数: 0

Treatment of patients with chronic airways obstruction: a controlled study with bamyphylline. bamyphyline治疗慢性气道阻塞的对照研究。

Pharmatherapeutica Pub Date : 1989-01-01

E Pulido, F Pupita, C Battistoni

引用次数: 0

Cefetamet pivoxil in paediatric patients suffering from lower respiratory tract infections. 头孢他美酯在小儿下呼吸道感染患者中的应用。

Pharmatherapeutica Pub Date : 1989-01-01

M Gatzola-Karaveli, N Vogiatzis, I Rousso, S Sklavuno-Tsurutsoglu, G Germano, M Kissling

引用次数: 0

Dose-effect relationship of terbutaline using a multi-dose powder inhalation system ('Turbuhaler') and salbutamol administered by powder inhalation ('Rotahaler') in asthmatics. 哮喘患者多剂量特布他林粉末吸入系统(“Turbuhaler”)与沙丁胺醇粉末吸入系统(“Rotahaler”)的剂量效应关系。

Pharmatherapeutica Pub Date : 1989-01-01

J M Bogaard, R Slingerland, A F Verbraak

{"title":"Dose-effect relationship of terbutaline using a multi-dose powder inhalation system ('Turbuhaler') and salbutamol administered by powder inhalation ('Rotahaler') in asthmatics.","authors":"J M Bogaard, R Slingerland, A F Verbraak","doi":"","DOIUrl":"","url":null,"abstract":"A study was carried out in 8 patients with chronic stable bronchial asthma to compare the bronchodilator response with terbutaline, administered by a recently developed powder inhalation system ('Turbuhaler') and equipotent doses of salbutamol administered by a widely used powder inhaler ('Rotahaler'). Dose-effect relationships with usually applied clinical doses of the bronchodilators were estimated by maximal expiratory flow-volume analysis and airway resistance estimates from body plethysmography. There was no significant difference in clinical response using either inhaler. The equal and opposite changes in forced vital capacity and residual volume with increasing dose indicate an improvement in peripheral airway resistance and, therefore, adequate peripheral powder deposition of the bronchodilators. Only at the highest dose was a mild increase noted in pulse frequency and tremor score with both systems. It is suggested that, because of the multi-dose character, absence of additives, easy handling (no capsule loading) and low inspiratory flow needed for actuation, the 'Turbuhaler' system may be considered preferable for the application of a bronchodilator in children and severely obstructed adults.","PeriodicalId":19862,"journal":{"name":"Pharmatherapeutica","volume":"5 6","pages":"400-6"},"PeriodicalIF":0.0,"publicationDate":"1989-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13738758","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Treatment and surgery of abdominal septic states: comparison of two antibiotic therapies]. [腹部脓毒症的治疗与手术:两种抗生素治疗的比较]。

Pharmatherapeutica Pub Date : 1989-01-01

D Levi, P Lemba, K Amery

引用次数: 0

Rapid infusion amphotericin B: effective and well-tolerated therapy for neutropenic fever. 快速输注两性霉素B:中性粒细胞减少热的有效且耐受性良好的治疗方法。

Pharmatherapeutica Pub Date : 1989-01-01

T R Spitzer, R J Creger, R M Fox, H M Lazarus

{"title":"Rapid infusion amphotericin B: effective and well-tolerated therapy for neutropenic fever.","authors":"T R Spitzer, R J Creger, R M Fox, H M Lazarus","doi":"","DOIUrl":"","url":null,"abstract":"A retrospective analysis was carried out of the results of 115 intensively-treated cancer inpatients receiving 91 treatment courses of amphotericin B given in an empirical fashion. Amphotericin B was administered over 1.5 to 2 hours at a dose of 0.6 to 0.7 mg/kg/day. Median duration of neutropenic fever before amphotericin B administration was 5 days (range 1 to 32 days) and median total amphotericin B dose was 480 mg (range 10 to 2450 mg). In 56 (61%) of 91 amphotericin B courses, neutropenic fevers resolved; this occurred a median of 3 days (range 1 to 15 days) after amphotericin B was begun and at a median dose of 120 mg (range 10 to 850 mg). Response to amphotericin was independent of positive cultures for fungus or sites of positive culture. Adverse reactions to amphotericin B included rigors (89% of courses), fever (23%), bronchospasm (9%), and transient hypotension (9%). Median increase above baseline serum creatinine in patients given amphotericin B was 0.5 mg/dl (range 0 to 2.6 mg/dl) compared to a median of 0.1 mg/dl (range 0 to 2.9 mg/dl) in a similar group of intensively-treated cancer patients who did not receive amphotericin B. Amphotericin B was well tolerated when given by rapid infusion and was associated with prompt resolution of neutropenic fever in the majority of patients.","PeriodicalId":19862,"journal":{"name":"Pharmatherapeutica","volume":"5 5","pages":"305-11"},"PeriodicalIF":0.0,"publicationDate":"1989-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13888608","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Prostaglandin E2 gel compared to oxytocin for medically-indicated labour induction at term: a controlled clinical trial. 前列腺素E2凝胶与催产素在足月引产中的比较:一项对照临床试验

Pharmatherapeutica Pub Date : 1988-01-01

A Silva-Cruz, F Godinho, J M Pinto, L Andrade, D Simões

{"title":"Prostaglandin E2 gel compared to oxytocin for medically-indicated labour induction at term: a controlled clinical trial.","authors":"A Silva-Cruz, F Godinho, J M Pinto, L Andrade, D Simões","doi":"","DOIUrl":"","url":null,"abstract":"A clinical trial was carried out to compare the efficacy and tolerance of two modes of induction of labour: vaginally administered prostaglandin E2 gel vs intravenous perfusion of synthetic oxytocin. Fifty women with pregnancy at or near term in whom prompt vaginal delivery was clinically indicated were divided at random into sub-groups of 25 each. Initial dose of PGE2 gel was 1 mg followed by another application of 1 mg or 2 mg 6 hours later in case active labour stage has not been reached. Progressive oxytocin perfusion began with 1 mU/min., being increased gradually every 20 minutes until efficacious uterine dynamics were attained. Data were recorded on entry of age, parity, gestation age, cervical dilatation, Bishop score, indication for induction. Continuous materno-foetal monitoring was carried out during the induction period. Results were evaluated from induction/delivery time, type of delivery, maternal and foetal condition, and any side-effects which developed. Apart from a higher number of instrumental deliveries in the PGE2 gel series, which was not related to the induction method, there was no significant difference between any of the variables evaluated, both methods producing active labour in approximately 70% of the patients within 12 hours. The authors stress, however, the convenience, both for patients and hospital staff, of the administration of an intravaginal induction agent over a systemic therapeutic method of induction.","PeriodicalId":19862,"journal":{"name":"Pharmatherapeutica","volume":"5 4","pages":"228-32"},"PeriodicalIF":0.0,"publicationDate":"1988-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14183685","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Comparative double-blind evaluation of a new topical antibacterial agent, mupirocin, compared with placebo in the treatment of skin and soft tissue infections]. [一种新的局部抗菌剂莫匹罗星与安慰剂治疗皮肤和软组织感染的比较双盲评价]。

Pharmatherapeutica Pub Date : 1988-01-01

M Colin, P Avon

引用次数: 0