Pharmacy & Pharmacology International Journal最新文献_第8页

An unexpected, revolutionary property of Artemisia infusions: immunoglobulins in the skin lead to a longlasting prophylaxis 一种意想不到的、革命性的青蒿输注特性:皮肤中的免疫球蛋白可以产生持久的预防作用

Pharmacy & Pharmacology International Journal Pub Date : 2020-02-13 DOI: 10.15406/ppij.2020.08.00280

P. Lutgen, Jérôme Munyangi, Pascal Gisenya, P. Ogwang

引用次数: 2

Study of the electrical activity of limbic brain structures after the destruction of the dorsal amygdalofugal pathway 杏仁核背侧通路破坏后脑边缘结构电活动的研究

Pharmacy & Pharmacology International Journal Pub Date : 2020-02-11 DOI: 10.15406/PPIJ.2020.08.00279

R. Baghirova

引用次数: 0

Bleomycin: An effective drug for intralesional injection treatment of vascular anomalies 博来霉素:局部注射治疗血管异常的有效药物

Pharmacy & Pharmacology International Journal Pub Date : 2020-02-10 DOI: 10.15406/PPIJ.2020.08.00278

A. Churojana

引用次数: 2

Cupriavius pauculus causing a respiratory tract infection in a post-kidney-transplant patient: A firstly described rare clinical case 1例肾移植后患者因包囊铜病毒引起呼吸道感染:首次报道的罕见临床病例

Pharmacy & Pharmacology International Journal Pub Date : 2020-02-07 DOI: 10.15406/PPIJ.2020.08.00277

D. Fiel, Rita Calça, Eunice Cacheira, Nuno Rombo, S. Querido, C. Nascimento, C. Jorge, A. Weigert, R. Birne, Belarmino Clemente, A. Martinho, C. Toscano, M. Bruges, Beatriz Malvar, D. Machado

{"title":"Cupriavius pauculus causing a respiratory tract infection in a post-kidney-transplant patient: A firstly described rare clinical case","authors":"D. Fiel, Rita Calça, Eunice Cacheira, Nuno Rombo, S. Querido, C. Nascimento, C. Jorge, A. Weigert, R. Birne, Belarmino Clemente, A. Martinho, C. Toscano, M. Bruges, Beatriz Malvar, D. Machado","doi":"10.15406/PPIJ.2020.08.00277","DOIUrl":"https://doi.org/10.15406/PPIJ.2020.08.00277","url":null,"abstract":"Cupriavidus pauculus is a gram-negative aerobic bacillus usually isolated from bottled mineral water, water from ultrafiltration systems in hospital setting and medical devices. Infections in humans are rare but usually severe, with most described cases of bacteremia, pneumonia, meningitis and sepsis. We describe a rare case of a Cupriavidus pauculus infection in a post-kidney-transplant context. A 60-year-old man, with Chronic Kidney Disease due to chronic glomerulonephritis, initiated hemodialysis in 1991 and received a cadaveric-donor kidney transplant in 1997. The graft functioned until 2008, when he returned to hemodialysis. After 2 years, he transited to Peritoneal Dialysis because of vascular access failure. He remained on PD for 7 years and received a new kidney transplant in 2018 after Encapsulating Peritoneal Sclerosis (EPS). The graft never gained function, so he remained peritoneal-dialysis-dependent. A few days after transplantation, peritonitis ensued ( Enteroccocus faecium , Serratia marcescens ). Even after Tenckhoff catheter removal, the clinical condition deteriorated, with need for continuous hemodiafiltration. The diagnose of a cecum perforation was made followed by hemicolectomy. Due to persisting respiratory and abdominal infections despite antibiotic regimens, and no kidney graft function, nephrectomy of the graft was performed, suspending immunosuppressive drugs. Later, a Cupriavidus pauculus was isolated in sputum, confirmed in two samples. Bacterial examination of the dialysis unit water system and equipment as well as of the ventilator used by the patient was negative. To our knowledge, this is the first case of a respiratory tract infection associated with Cupriavidus pauculus described in a post-kidney-transplant patient.","PeriodicalId":19839,"journal":{"name":"Pharmacy & Pharmacology International Journal","volume":"43 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76679350","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Evaluation of antioxidant properties of angiotensinconverting enzyme inhibitors-interactions with free radicals model examined by EPR spectroscopy 血管紧张素转换酶抑制剂抗氧化性能的评价——EPR光谱研究与自由基的相互作用模型

Pharmacy & Pharmacology International Journal Pub Date : 2020-01-30 DOI: 10.15406/PPIJ.2020.08.00276

A. Juszczak, P. Ramos, Wojciech Szczolko, B. Pilawa, B. Stanisz

引用次数: 0

Estimation of B-vitamins (B1, B2, B3 and B6) by HPLC in vegetables including ethnic selected varieties of Bangladesh HPLC法测定孟加拉国少数民族蔬菜中b族维生素(B1、B2、B3和B6)含量

Pharmacy & Pharmacology International Journal Pub Date : 2020-01-28 DOI: 10.15406/PPIJ.2020.08.00275

F. Zohora, Sneha Sarwar, Ontora Khatun, Praveen Begum, M. Khatun, M. Ahsan, S. N. Islam

引用次数: 3

Risk management model in patients receiving therapy with biotechnological medications for rheumatoid arthritis in a medical center in Barranquilla, Colombia 哥伦比亚巴兰基亚某医疗中心接受类风湿性关节炎生物技术药物治疗的患者风险管理模型

Pharmacy & Pharmacology International Journal Pub Date : 2020-01-09 DOI: 10.15406/PPIJ.2020.08.00274

Julia Aracelly Gonzalez Puertas, M. Duran, J. Durán, E. Manrique, B. Palácio, I. Pereira, E. Caballero, E Cabas

{"title":"Risk management model in patients receiving therapy with biotechnological medications for rheumatoid arthritis in a medical center in Barranquilla, Colombia","authors":"Julia Aracelly Gonzalez Puertas, M. Duran, J. Durán, E. Manrique, B. Palácio, I. Pereira, E. Caballero, E Cabas","doi":"10.15406/PPIJ.2020.08.00274","DOIUrl":"https://doi.org/10.15406/PPIJ.2020.08.00274","url":null,"abstract":"Rheumatoid arthritis (RA) is a condition of multifactorial origin, characterized by inflammation and hyperplasia of the synovial membrane of the diarthrodial joints, predominantly of the hands and feet, in which there is production of autoantibodies, destruction of cartilage and subchondral bone, and it is usually accompanied by systemic manifestations such as nodules, cardiovascular disease and pulmonary involvement. Proper and early management improves the evolution and prognosis of the disease.1 The therapy comprises synthetic and biological disease modifying drugs which have serious side effects and, in the case of biological therapy, represents a potential risk of developing infectious diseases and other effects, associated with their mechanism of action.2 The main objective of this study is the identification of the drug-related problems (DRP) and classification of negative clinical outcome (NCO) according to their Necessity, Effectiveness and Safety of pharmacological therapy, through the implementation of a risk management program that prevents or minimizes these adverse health outcomes of patients with rheumatoid arthritis.","PeriodicalId":19839,"journal":{"name":"Pharmacy & Pharmacology International Journal","volume":"68 1","pages":"11-14"},"PeriodicalIF":0.0,"publicationDate":"2020-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85027105","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pharmacological treatment of fibromyalgia 纤维肌痛的药物治疗

Pharmacy & Pharmacology International Journal Pub Date : 2020-01-07 DOI: 10.15406/PPIJ.2020.08.00273

Diana Yisenia Pinzon Fajardo, José Julián López Gutiérrez, Jorge Mario Camacho Carvajal

{"title":"Pharmacological treatment of fibromyalgia","authors":"Diana Yisenia Pinzon Fajardo, José Julián López Gutiérrez, Jorge Mario Camacho Carvajal","doi":"10.15406/PPIJ.2020.08.00273","DOIUrl":"https://doi.org/10.15406/PPIJ.2020.08.00273","url":null,"abstract":"Fibromyalgia (FM) is a complex and little known disease, health professionals face a pathology with a difficult diagnosis, without a therapeutic target, which causes a high burden of morbidity and costs.1–4 There is no single treatment that has proven effective. Several attempts have been made to elucidate the best ways to diagnose and treat FM, but so far no objective evidence has been found to allow the diagnosis to be made or ruled out.1,5–7 Functional magnetic resonance imaging and biochemical marker tests are not useful because they indicate the existence of pain, but not its cause.8,9 This leads to the diagnosis being controversial because it is based only on subjective criteria, which can cause a misdiagnosis of the disease, since each doctor can give a different interpretation has shown that not all doctors know the criteria from the American College of Rheumatology (ACR) to establish a diagnosis.10–12 This is sometimes because many doctors do not accept FM as a pathology, and consider it as a poor adaptive response to stress or depression, increasing patient frustration and generating poor adherence to medical management, which leads to rupture of the doctor-patient relationship. One of the contradictors of the FM is Dr. Frederick Wolfe, director of the National Data Bank for Rheumatic Diseases and lead author of the 1990 article that first defined the diagnostic guidelines for FM, who considers that it is not a disease if not a physical response to stress, depression and economic and social anxiety. Wolfe said that “some of us in those days thought that we had actually identified a disease, which clearly is not,” “Making people sick, making them sick, was something wrong.” Therefore, FM is considered not It requires no pharmacological treatment and that this has only been driven by the profits produced by the sale and commercialization of some medications as without being clear about how it reduces pain.5,11","PeriodicalId":19839,"journal":{"name":"Pharmacy & Pharmacology International Journal","volume":"54 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83200483","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The surplus value of Azorean Camellia sinensis flowers as an important contributor affecting the nutraceutical benefits of green tea quality 亚速尔山茶花的剩余价值是影响绿茶品质营养效益的重要因素

Pharmacy & Pharmacology International Journal Pub Date : 2019-12-23 DOI: 10.15406/ppij.2019.07.00272

J. Baptista, Lisete S. Paiva, E. Lima, Madalena Motta

引用次数: 2

Paraspinal extramedullary hematopoiesis in alpha-thalassemia with concurrent monoclonal gammopathy of undetermined significance: an uncommon case report α -地中海贫血并发单克隆伽玛病的椎旁髓外造血:一罕见病例报告

Pharmacy & Pharmacology International Journal Pub Date : 2019-12-12 DOI: 10.15406/ppij.2019.07.00270

Angeliki Tsifi, Ioannis Tsifis, Anatol Vieru, M. Triantafyllou, D. Theodoridis, Stavroula-Panagiota Lontou, M. Mantzourani

{"title":"Paraspinal extramedullary hematopoiesis in alpha-thalassemia with concurrent monoclonal gammopathy of undetermined significance: an uncommon case report","authors":"Angeliki Tsifi, Ioannis Tsifis, Anatol Vieru, M. Triantafyllou, D. Theodoridis, Stavroula-Panagiota Lontou, M. Mantzourani","doi":"10.15406/ppij.2019.07.00270","DOIUrl":"https://doi.org/10.15406/ppij.2019.07.00270","url":null,"abstract":"Extramedullary hematopoiesis (EMH) functions as a compensatory phenomenon in cases of insufficient bone marrow function and refers to the hematopoiesis that takes place outside the medulla of the bone. It is usually associated with various hematologic disorders, including thalassemia.1–4 Hemoglobin H disease is a type of a-thalassemia consisting of the loss of 3 genes (--/-a) and is often manifested as a mild anemia with thalassemic morphological changes and the existence of erythrocyte inclusions. Hemoglobin H is a tetramer composed of four beta globin chains and a great decrease in alpha chain availability.5 In this hemolytic disorder, splenomegaly may occur, as well as mandibular and bone marrow hyperplasia and pathological fractures. Reported herein is the case of a 64-year-old male who suddenly developed a mild anemia, splenomegaly, monoclonal hypergammaglobulinemia and a paraspinal mass and was admitted to our hospital for further investigation. The patient was eventually diagnosed with hemoglobin H disease with concurrent MGUS. The present case report discusses the diagnostic methods, problems and treatment strategies that were applied and seeks to further examine this uncommon clinical manifestation. Case presentation","PeriodicalId":19839,"journal":{"name":"Pharmacy & Pharmacology International Journal","volume":"16 1","pages":"315-317"},"PeriodicalIF":0.0,"publicationDate":"2019-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75727850","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0