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Pharmacological research communications最新文献

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Prolactin affects central dopamine receptor function: The behavioral model of aged rats 催乳素影响老年大鼠中枢多巴胺受体功能的行为模型
Pharmacological research communications Pub Date : 1988-12-01 Epub Date: 2007-09-04 DOI: 10.1016/S0031-6989(88)80746-X
Filippo Drago, Francesco Spadaro, Umberto Scapagnini
{"title":"Prolactin affects central dopamine receptor function: The behavioral model of aged rats","authors":"Filippo Drago, Francesco Spadaro, Umberto Scapagnini","doi":"10.1016/S0031-6989(88)80746-X","DOIUrl":"10.1016/S0031-6989(88)80746-X","url":null,"abstract":"","PeriodicalId":19810,"journal":{"name":"Pharmacological research communications","volume":"20 12","pages":"Pages 1101-1102"},"PeriodicalIF":0.0,"publicationDate":"1988-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0031-6989(88)80746-X","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14341179","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Serotonin release and metabolism in rat cortex as studied by transcerebral dialysis 经脑透析研究大鼠皮层血清素释放及代谢
Pharmacological research communications Pub Date : 1988-12-01 Epub Date: 2007-09-04 DOI: 10.1016/S0031-6989(88)80751-3
L. Perezzani, E. Carboni, D. Belelli, G. Di Chiara
{"title":"Serotonin release and metabolism in rat cortex as studied by transcerebral dialysis","authors":"L. Perezzani, E. Carboni, D. Belelli, G. Di Chiara","doi":"10.1016/S0031-6989(88)80751-3","DOIUrl":"10.1016/S0031-6989(88)80751-3","url":null,"abstract":"","PeriodicalId":19810,"journal":{"name":"Pharmacological research communications","volume":"20 12","pages":"Pages 1111-1112"},"PeriodicalIF":0.0,"publicationDate":"1988-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0031-6989(88)80751-3","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13608259","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Dihydroergocristine improves behavioral deficits of aged rats 二氢麦角新碱改善老年大鼠的行为缺陷
Pharmacological research communications Pub Date : 1988-12-01 Epub Date: 2007-09-04 DOI: 10.1016/S0031-6989(88)80755-0
Velia D'Agata, Francesco Spadaro, Filippo Drago
{"title":"Dihydroergocristine improves behavioral deficits of aged rats","authors":"Velia D'Agata, Francesco Spadaro, Filippo Drago","doi":"10.1016/S0031-6989(88)80755-0","DOIUrl":"10.1016/S0031-6989(88)80755-0","url":null,"abstract":"","PeriodicalId":19810,"journal":{"name":"Pharmacological research communications","volume":"20 12","pages":"Pages 1119-1120"},"PeriodicalIF":0.0,"publicationDate":"1988-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0031-6989(88)80755-0","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14277025","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Effect of cadmium on germination, growth and active principle contents of Achillea Millefolium L. 镉对水蛭萌发、生长及活性成分含量的影响。
Pharmacological research communications Pub Date : 1988-12-01 Epub Date: 2009-02-19 DOI: 10.1016/S0031-6989(88)80860-9
R. De Pasquale , S. Ragusa , L. Iauk , R. Barbera , E.M. Galati
{"title":"Effect of cadmium on germination, growth and active principle contents of Achillea Millefolium L.","authors":"R. De Pasquale ,&nbsp;S. Ragusa ,&nbsp;L. Iauk ,&nbsp;R. Barbera ,&nbsp;E.M. Galati","doi":"10.1016/S0031-6989(88)80860-9","DOIUrl":"10.1016/S0031-6989(88)80860-9","url":null,"abstract":"<div><p>Effects on germination, growth and active principle contents of Achillea millefolium L. of an increase of cadmium concentration in soil and in atmosphere were investigated. Soil pollution reduced germination and growth. No significant differences were found in GLC analysis of all plants extracts.</p></div>","PeriodicalId":19810,"journal":{"name":"Pharmacological research communications","volume":"20 ","pages":"Pages 145-149"},"PeriodicalIF":0.0,"publicationDate":"1988-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0031-6989(88)80860-9","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14376277","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 6
Effect of cadmium on germination, growth and active principle contents of Matricaria recutita L. 镉对苦荬菜萌发、生长及活性成分含量的影响。
Pharmacological research communications Pub Date : 1988-12-01 Epub Date: 2009-02-19 DOI: 10.1016/S0031-6989(88)80861-0
R. De Pasquale , S. Ragusa , L. Iauk , R. Barbera , E.M. Galati
{"title":"Effect of cadmium on germination, growth and active principle contents of Matricaria recutita L.","authors":"R. De Pasquale ,&nbsp;S. Ragusa ,&nbsp;L. Iauk ,&nbsp;R. Barbera ,&nbsp;E.M. Galati","doi":"10.1016/S0031-6989(88)80861-0","DOIUrl":"10.1016/S0031-6989(88)80861-0","url":null,"abstract":"<div><p>The effects on Matricaria recutita L. of an increase of cadmium concentration in soil and in atmosphere were investigated. Data on germination, survival, growth and dry weight were collected and methilenic extracts of the drugs were analyzed. Cd pollution affects Matricaria germination and growth and GLC analysis of extracts shows a significant difference in active principles between the plants subject undergone different treatments.</p></div>","PeriodicalId":19810,"journal":{"name":"Pharmacological research communications","volume":"20 ","pages":"Pages 151-154"},"PeriodicalIF":0.0,"publicationDate":"1988-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0031-6989(88)80861-0","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14376278","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 8
Anti-inflammatory activity of Echinacea angustifolia fractions separated on the basis of molecular weight 基于分子量分离的紫锥菊提取物的抗炎活性
Pharmacological research communications Pub Date : 1988-12-01 Epub Date: 2009-02-19 DOI: 10.1016/S0031-6989(88)80848-8
E. Tragni , C.L. Galli , A. Tubaro , P. Del Negro , R. Della Loggia
{"title":"Anti-inflammatory activity of Echinacea angustifolia fractions separated on the basis of molecular weight","authors":"E. Tragni ,&nbsp;C.L. Galli ,&nbsp;A. Tubaro ,&nbsp;P. Del Negro ,&nbsp;R. Della Loggia","doi":"10.1016/S0031-6989(88)80848-8","DOIUrl":"10.1016/S0031-6989(88)80848-8","url":null,"abstract":"<div><p>Five fractions of an aqueous extract obtained from the roots of <u>Echinacea angustifolia</u> were separated on the basis of molecular weight. The topical anti-inflammatory activity of the fractions has been evaluated in mice using the Croton oil ear test. The fraction with a molecular weight between 30,000 and 100,000 was the most active in inhibiting the oedema; it also reduced the infiltration of inflammatory cells. The activity of this fraction was comparable with that of a raw polysaccharidic extract obtained from <u>E. angustifolia</u> roots by differential solubility. The high-molecular weigth polysaccharides are therefore proposed as the anti-inflammatory principles of the plant.</p></div>","PeriodicalId":19810,"journal":{"name":"Pharmacological research communications","volume":"20 ","pages":"Pages 87-90"},"PeriodicalIF":0.0,"publicationDate":"1988-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0031-6989(88)80848-8","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14376292","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 38
Interference of flunoxaprofen, a non-steroidal anti-inflammatory agent, on the antihypertensive activity of etozoline 非甾体抗炎药氟诺卡洛芬对依托唑啉降压活性的干扰
Pharmacological research communications Pub Date : 1988-12-01 Epub Date: 2007-09-04 DOI: 10.1016/S0031-6989(88)80758-6
M. Lisa, C. Losasso, G.F. Conte, A. Loffreda, V. de Novellis, N. Carapella
{"title":"Interference of flunoxaprofen, a non-steroidal anti-inflammatory agent, on the antihypertensive activity of etozoline","authors":"M. Lisa,&nbsp;C. Losasso,&nbsp;G.F. Conte,&nbsp;A. Loffreda,&nbsp;V. de Novellis,&nbsp;N. Carapella","doi":"10.1016/S0031-6989(88)80758-6","DOIUrl":"10.1016/S0031-6989(88)80758-6","url":null,"abstract":"","PeriodicalId":19810,"journal":{"name":"Pharmacological research communications","volume":"20 12","pages":"Pages 1125-1126"},"PeriodicalIF":0.0,"publicationDate":"1988-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0031-6989(88)80758-6","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14341183","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Neuro-endocrine changes as new targets in the drug treatment of congestive heart failure 充血性心力衰竭药物治疗的新靶点:神经内分泌变化
Pharmacological research communications Pub Date : 1988-12-01 Epub Date: 2007-09-04 DOI: 10.1016/S0031-6989(88)80723-9
P.A. van Zwieten MD PhD
{"title":"Neuro-endocrine changes as new targets in the drug treatment of congestive heart failure","authors":"P.A. van Zwieten MD PhD","doi":"10.1016/S0031-6989(88)80723-9","DOIUrl":"10.1016/S0031-6989(88)80723-9","url":null,"abstract":"<div><p>The classical therapy of congestive heart failure (CHF) with inotropic agents (digitalis and newer inotropics) and diuretic agents remains unsatisfactory in many cases. More recently it is recognized, that some of the neuro-endocrine compensatory processes associated with CHF are detrimental in the long run, and therefore potentially targets for drug treatment. This holds for the following neuro-endocrine mechanisms:<span>o<ol><li><span>1)</span><span><p>increased activity of the sympathetic nervous system and high plasma catecholamines, accompanied by down-regulation of β<sub>1</sub>- but not β<sub>2</sub>-receptors in the heart:</p></span></li><li><span>2)</span><span><p>stimulation of the renin-angiotensin-aldosterone system (RAAS), causing higher levels of renin, A II and aldosterone.</p></span></li></ol></span></p><p>The detrimental sequelae of both processes are even enhanced by their complex mutual interactions. Drug treatment aiming to reduce or suppress these processes and their negative results is potentially offered by: vasodilators, counteracting vasoconstriction, low dose selective β<sub>1</sub>-adrenoceptor blockers, which will not only impair tachycardia but also upregulate cardiac β<sub>1</sub>-recep-</p></div>","PeriodicalId":19810,"journal":{"name":"Pharmacological research communications","volume":"20 12","pages":"Pages 1017-1023"},"PeriodicalIF":0.0,"publicationDate":"1988-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0031-6989(88)80723-9","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14042078","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Voltage-dependent Ca2+ channels in primary cultures of cerebellar granule cells: Modulatory action by an endogenous ligand 小脑颗粒细胞原代培养中电压依赖性Ca2+通道:内源性配体的调节作用
Pharmacological research communications Pub Date : 1988-12-01 Epub Date: 2007-09-04 DOI: 10.1016/S0031-6989(88)80738-0
E. Sanna , I. Hanbauer
{"title":"Voltage-dependent Ca2+ channels in primary cultures of cerebellar granule cells: Modulatory action by an endogenous ligand","authors":"E. Sanna ,&nbsp;I. Hanbauer","doi":"10.1016/S0031-6989(88)80738-0","DOIUrl":"10.1016/S0031-6989(88)80738-0","url":null,"abstract":"","PeriodicalId":19810,"journal":{"name":"Pharmacological research communications","volume":"20 12","pages":"Pages 1085-1086"},"PeriodicalIF":0.0,"publicationDate":"1988-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0031-6989(88)80738-0","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13986585","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Chronic SCH 23390 produces tolerance to morphine extrapiramidal effects 慢性SCH 23390对吗啡产生耐受性
Pharmacological research communications Pub Date : 1988-12-01 Epub Date: 2007-09-04 DOI: 10.1016/S0031-6989(88)80753-7
M.G. De Montis, P. Devoto, P. Saba, A. Porcella, D. Meloni, A. Tagliamonte
{"title":"Chronic SCH 23390 produces tolerance to morphine extrapiramidal effects","authors":"M.G. De Montis,&nbsp;P. Devoto,&nbsp;P. Saba,&nbsp;A. Porcella,&nbsp;D. Meloni,&nbsp;A. Tagliamonte","doi":"10.1016/S0031-6989(88)80753-7","DOIUrl":"10.1016/S0031-6989(88)80753-7","url":null,"abstract":"","PeriodicalId":19810,"journal":{"name":"Pharmacological research communications","volume":"20 12","pages":"Pages 1115-1116"},"PeriodicalIF":0.0,"publicationDate":"1988-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0031-6989(88)80753-7","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13986587","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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