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Pharmacological research communications最新文献

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Computerized tridimensional reconstruction of vegetable structures 蔬菜结构的计算机三维重建
Pharmacological research communications Pub Date : 1988-12-01 DOI: 10.1016/S0031-6989(88)80859-2
Buffo G. , Princi P. , Tumino G. , De Pasquale A.
{"title":"Computerized tridimensional reconstruction of vegetable structures","authors":"Buffo G. ,&nbsp;Princi P. ,&nbsp;Tumino G. ,&nbsp;De Pasquale A.","doi":"10.1016/S0031-6989(88)80859-2","DOIUrl":"10.1016/S0031-6989(88)80859-2","url":null,"abstract":"<div><p>By means of a “Personal Computer”, a technique has been worked out for the acquisition and processing of data, for the tridimensional reconstruction of vegetable structures starting out from information, in the form of photographic images, obtained by optical or electronic microscope.</p><p>Examples fo the application of this program to vegetable drugs (corolla of Lavandula anqustifolia Mill. flowers) are given.</p></div>","PeriodicalId":19810,"journal":{"name":"Pharmacological research communications","volume":"20 ","pages":"Pages 139-144"},"PeriodicalIF":0.0,"publicationDate":"1988-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0031-6989(88)80859-2","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14377597","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Antibacterial activity of some African medicinal plants 一些非洲药用植物的抗菌活性
Pharmacological research communications Pub Date : 1988-12-01 DOI: 10.1016/S0031-6989(88)80835-X
Forestieri A.M., Pizzimenti F.C., Monforte M.T., Bisignano G.
{"title":"Antibacterial activity of some African medicinal plants","authors":"Forestieri A.M.,&nbsp;Pizzimenti F.C.,&nbsp;Monforte M.T.,&nbsp;Bisignano G.","doi":"10.1016/S0031-6989(88)80835-X","DOIUrl":"10.1016/S0031-6989(88)80835-X","url":null,"abstract":"<div><p>The antimicrobial activity of some drugs utilized in traditional African medicine and selected on the basis of medicinal folklore reports, have been studied, within a screening program. The distribution of the antimicrobial activity among gram-positive, gram-negative bacteria, yeasts and mycoplasma is reported.</p></div>","PeriodicalId":19810,"journal":{"name":"Pharmacological research communications","volume":"20 ","pages":"Pages 33-36"},"PeriodicalIF":0.0,"publicationDate":"1988-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0031-6989(88)80835-X","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14376281","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 16
Effects of Trema guineense decoction on some metabolic activities in the rat 鼠耳汤对大鼠某些代谢活动的影响
Pharmacological research communications Pub Date : 1988-12-01 DOI: 10.1016/S0031-6989(88)80842-7
A. Trovato, A.M. Forestieri, R. Barbera, E.M. Galati
{"title":"Effects of Trema guineense decoction on some metabolic activities in the rat","authors":"A. Trovato,&nbsp;A.M. Forestieri,&nbsp;R. Barbera,&nbsp;E.M. Galati","doi":"10.1016/S0031-6989(88)80842-7","DOIUrl":"10.1016/S0031-6989(88)80842-7","url":null,"abstract":"<div><p>Summary</p><p>The present study was undertaken to define the effects of <u>Trema guineense</u> (Schum. and Thonn.) Ficalho (Ulmaceae) on some metabolic activity in the rat. A decoction of leaves, administered by gastric intubation, lowers haematic uric acid levels and increases urinary elimination of the same acid. No changes in the blood glucose and cholesterol levels were observed.</p></div>","PeriodicalId":19810,"journal":{"name":"Pharmacological research communications","volume":"20 ","pages":"Pages 63-65"},"PeriodicalIF":0.0,"publicationDate":"1988-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0031-6989(88)80842-7","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14376288","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Voltage-dependent Ca2+ channels in primary cultures of cerebellar granule cells: Modulatory action by an endogenous ligand 小脑颗粒细胞原代培养中电压依赖性Ca2+通道:内源性配体的调节作用
Pharmacological research communications Pub Date : 1988-12-01 DOI: 10.1016/S0031-6989(88)80738-0
E. Sanna , I. Hanbauer
{"title":"Voltage-dependent Ca2+ channels in primary cultures of cerebellar granule cells: Modulatory action by an endogenous ligand","authors":"E. Sanna ,&nbsp;I. Hanbauer","doi":"10.1016/S0031-6989(88)80738-0","DOIUrl":"10.1016/S0031-6989(88)80738-0","url":null,"abstract":"","PeriodicalId":19810,"journal":{"name":"Pharmacological research communications","volume":"20 12","pages":"Pages 1085-1086"},"PeriodicalIF":0.0,"publicationDate":"1988-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0031-6989(88)80738-0","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13986585","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Chronic SCH 23390 produces tolerance to morphine extrapiramidal effects 慢性SCH 23390对吗啡产生耐受性
Pharmacological research communications Pub Date : 1988-12-01 DOI: 10.1016/S0031-6989(88)80753-7
M.G. De Montis, P. Devoto, P. Saba, A. Porcella, D. Meloni, A. Tagliamonte
{"title":"Chronic SCH 23390 produces tolerance to morphine extrapiramidal effects","authors":"M.G. De Montis,&nbsp;P. Devoto,&nbsp;P. Saba,&nbsp;A. Porcella,&nbsp;D. Meloni,&nbsp;A. Tagliamonte","doi":"10.1016/S0031-6989(88)80753-7","DOIUrl":"10.1016/S0031-6989(88)80753-7","url":null,"abstract":"","PeriodicalId":19810,"journal":{"name":"Pharmacological research communications","volume":"20 12","pages":"Pages 1115-1116"},"PeriodicalIF":0.0,"publicationDate":"1988-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0031-6989(88)80753-7","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13986587","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Oxytocin-induced penile erection and yawning: Structure-activity relationship studies 催产素诱导的阴茎勃起和打哈欠:构效关系研究
Pharmacological research communications Pub Date : 1988-12-01 DOI: 10.1016/S0031-6989(88)80754-9
M.R. Melis, A. Argiolas, R. Stancampino, G.L. Gessa
{"title":"Oxytocin-induced penile erection and yawning: Structure-activity relationship studies","authors":"M.R. Melis,&nbsp;A. Argiolas,&nbsp;R. Stancampino,&nbsp;G.L. Gessa","doi":"10.1016/S0031-6989(88)80754-9","DOIUrl":"10.1016/S0031-6989(88)80754-9","url":null,"abstract":"","PeriodicalId":19810,"journal":{"name":"Pharmacological research communications","volume":"20 12","pages":"Pages 1117-1118"},"PeriodicalIF":0.0,"publicationDate":"1988-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0031-6989(88)80754-9","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13986588","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Neuro-endocrine changes as new targets in the drug treatment of congestive heart failure 充血性心力衰竭药物治疗的新靶点:神经内分泌变化
Pharmacological research communications Pub Date : 1988-12-01 DOI: 10.1016/S0031-6989(88)80723-9
P.A. van Zwieten MD PhD
{"title":"Neuro-endocrine changes as new targets in the drug treatment of congestive heart failure","authors":"P.A. van Zwieten MD PhD","doi":"10.1016/S0031-6989(88)80723-9","DOIUrl":"10.1016/S0031-6989(88)80723-9","url":null,"abstract":"<div><p>The classical therapy of congestive heart failure (CHF) with inotropic agents (digitalis and newer inotropics) and diuretic agents remains unsatisfactory in many cases. More recently it is recognized, that some of the neuro-endocrine compensatory processes associated with CHF are detrimental in the long run, and therefore potentially targets for drug treatment. This holds for the following neuro-endocrine mechanisms:<span>o<ol><li><span>1)</span><span><p>increased activity of the sympathetic nervous system and high plasma catecholamines, accompanied by down-regulation of β<sub>1</sub>- but not β<sub>2</sub>-receptors in the heart:</p></span></li><li><span>2)</span><span><p>stimulation of the renin-angiotensin-aldosterone system (RAAS), causing higher levels of renin, A II and aldosterone.</p></span></li></ol></span></p><p>The detrimental sequelae of both processes are even enhanced by their complex mutual interactions. Drug treatment aiming to reduce or suppress these processes and their negative results is potentially offered by: vasodilators, counteracting vasoconstriction, low dose selective β<sub>1</sub>-adrenoceptor blockers, which will not only impair tachycardia but also upregulate cardiac β<sub>1</sub>-recep-</p></div>","PeriodicalId":19810,"journal":{"name":"Pharmacological research communications","volume":"20 12","pages":"Pages 1017-1023"},"PeriodicalIF":0.0,"publicationDate":"1988-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0031-6989(88)80723-9","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14042078","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Interference of flunoxaprofen, a non-steroidal anti-inflammatory agent, on the antihypertensive activity of etozoline 非甾体抗炎药氟诺卡洛芬对依托唑啉降压活性的干扰
Pharmacological research communications Pub Date : 1988-12-01 DOI: 10.1016/S0031-6989(88)80758-6
M. Lisa, C. Losasso, G.F. Conte, A. Loffreda, V. de Novellis, N. Carapella
{"title":"Interference of flunoxaprofen, a non-steroidal anti-inflammatory agent, on the antihypertensive activity of etozoline","authors":"M. Lisa,&nbsp;C. Losasso,&nbsp;G.F. Conte,&nbsp;A. Loffreda,&nbsp;V. de Novellis,&nbsp;N. Carapella","doi":"10.1016/S0031-6989(88)80758-6","DOIUrl":"10.1016/S0031-6989(88)80758-6","url":null,"abstract":"","PeriodicalId":19810,"journal":{"name":"Pharmacological research communications","volume":"20 12","pages":"Pages 1125-1126"},"PeriodicalIF":0.0,"publicationDate":"1988-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0031-6989(88)80758-6","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14341183","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of cadmium on germination, growth and active principle contents of Achillea Millefolium L. 镉对水蛭萌发、生长及活性成分含量的影响。
Pharmacological research communications Pub Date : 1988-12-01 DOI: 10.1016/S0031-6989(88)80860-9
R. De Pasquale , S. Ragusa , L. Iauk , R. Barbera , E.M. Galati
{"title":"Effect of cadmium on germination, growth and active principle contents of Achillea Millefolium L.","authors":"R. De Pasquale ,&nbsp;S. Ragusa ,&nbsp;L. Iauk ,&nbsp;R. Barbera ,&nbsp;E.M. Galati","doi":"10.1016/S0031-6989(88)80860-9","DOIUrl":"10.1016/S0031-6989(88)80860-9","url":null,"abstract":"<div><p>Effects on germination, growth and active principle contents of Achillea millefolium L. of an increase of cadmium concentration in soil and in atmosphere were investigated. Soil pollution reduced germination and growth. No significant differences were found in GLC analysis of all plants extracts.</p></div>","PeriodicalId":19810,"journal":{"name":"Pharmacological research communications","volume":"20 ","pages":"Pages 145-149"},"PeriodicalIF":0.0,"publicationDate":"1988-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0031-6989(88)80860-9","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14376277","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 6
Effect of cadmium on germination, growth and active principle contents of Matricaria recutita L. 镉对苦荬菜萌发、生长及活性成分含量的影响。
Pharmacological research communications Pub Date : 1988-12-01 DOI: 10.1016/S0031-6989(88)80861-0
R. De Pasquale , S. Ragusa , L. Iauk , R. Barbera , E.M. Galati
{"title":"Effect of cadmium on germination, growth and active principle contents of Matricaria recutita L.","authors":"R. De Pasquale ,&nbsp;S. Ragusa ,&nbsp;L. Iauk ,&nbsp;R. Barbera ,&nbsp;E.M. Galati","doi":"10.1016/S0031-6989(88)80861-0","DOIUrl":"10.1016/S0031-6989(88)80861-0","url":null,"abstract":"<div><p>The effects on Matricaria recutita L. of an increase of cadmium concentration in soil and in atmosphere were investigated. Data on germination, survival, growth and dry weight were collected and methilenic extracts of the drugs were analyzed. Cd pollution affects Matricaria germination and growth and GLC analysis of extracts shows a significant difference in active principles between the plants subject undergone different treatments.</p></div>","PeriodicalId":19810,"journal":{"name":"Pharmacological research communications","volume":"20 ","pages":"Pages 151-154"},"PeriodicalIF":0.0,"publicationDate":"1988-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0031-6989(88)80861-0","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14376278","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 8
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