{"title":"CATECHOL-O-METHYLTRANSFERASE (COMT) ENZYME LEVELS IN PATIENTS WITH PREOPERATIVE ANXIETY","authors":"Akhyar Hamongan Nasution, A. Lelo","doi":"10.55047/comorbid.v1i1.37","DOIUrl":"https://doi.org/10.55047/comorbid.v1i1.37","url":null,"abstract":"\u0000The preoperative anxiety’s incidence is very high and mostly preoperative patients have anxiety. It was found that low COMT levels indicate a tendency to develop anxiety. Hence, this study aims to investigate COMT enzyme levels in patients with preoperative anxiety. This research is a purely experimental research with a pretest-posttest control group design and double-blind. Measurement of COMT enzyme levels was executed by utilizing ELISA technique. Blood samples were taken from preoperative anxiety patients who were assessed with the Amsterdam Preoperative Anxiety Information Scale (APAIS). The research was carried out at Haji Adam Malik General Hospital and Regional General Hospital dr. Pirngadi Medan, and Integrated Laboratory of the Faculty of Medicine, University of North Sumatra. The were 64 samples involved in this research that fit the inclusion and exclusion criteria. The findings show that COMT levels in the anxiety and control groups had differences with p values = 0.014. In addition, COMT levels in the preoperative anxiety group were lower when compared to those without the preoperative anxiety group, where in the anxiety group had COMT enzyme levels of 0,14 ± 0,08 ng/dl, while in the control group had higher COMT levels 0,96 ± 1,11 ng/dl. The results showed that patients with preoperative anxiety had lower levels of the COMT enzyme compared to patients without preoperative anxiety. Researchers suspect there is a role for the COMT enzyme in causing preoperative anxiety. \u0000 \u0000 \u0000 \u0000 \u0000 \u0000 \u0000 \u0000 \u0000 \u0000","PeriodicalId":19772,"journal":{"name":"PHARMACOLOGY, MEDICAL REPORTS, ORTHOPEDIC, AND ILLNESS DETAILS (COMORBID)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75451471","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"CLEAN AND HEALTHY LIVING BEHAVIOR IN THE FAMILY ENVIRONMENT AS A PREVENTION OF COVID-19 IN SERANG CITY","authors":"Stevany Afrizal, Inez Athallaisya Adinda","doi":"10.55047/comorbid.v1i1.35","DOIUrl":"https://doi.org/10.55047/comorbid.v1i1.35","url":null,"abstract":"\u0000The rapid spread of the COVID-19 virus throughout the world has come as a complete shock, and it is causing serious concerns. The COVID-19 virus can be prevented with the help of a simple yet highly successful method called \"clean and healthy living behavior\" (PHBS). The health of family members is expected to improve as a result of the implementation of clean and healthy living behavior (PHBS) in the family environment, which includes adhering to health protocols, staying at home for those who do not have to leave the house, and allowing workers or employees to work from home (Work From Home/WFH). Family participation in PHBS is essential in order to prevent COVID-19 from spreading, as demonstrated by the emergence of COVID-19. The objective of this paper is to educate the community and families about PHBS, as well as to ensure that it is properly implemented. Descriptive qualitative interviews and scientific references are employed to perform the research. The researcher chose this title because he wants to break the chain of the COVID-19 virus's transmission in order to establish a family environment that is mindful of health and enhancing a healthy and clean family environment, so that people do not get sick as easily as before. A healthy family environment can increase productivity, so that family members will get used to implementing PHBS and children can grow up healthy and have adequate nutrition. \u0000 \u0000 \u0000 \u0000 \u0000 \u0000 \u0000 \u0000 \u0000 \u0000","PeriodicalId":19772,"journal":{"name":"PHARMACOLOGY, MEDICAL REPORTS, ORTHOPEDIC, AND ILLNESS DETAILS (COMORBID)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90654560","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}