Oral abstractsPub Date : 2021-11-01DOI: 10.1136/ijgc-2021-igcs.2
V. Makker, N. Colombo, A. Casado Herráez, A. Santin, E. Colomba, D. Miller, K. Fujiwara, S. Pignata, Sri Banerjee, B. Monk, K. Ushijima, R. Penson, R. Kristeleit, M. Fabbro, M. Orlando, H. Mackay, M. Ren, R. Orlowski, L. Dutta, D. Lorusso
{"title":"O002/#43 Randomized phase 3 study of lenvatinib plus pembrolizumab for advanced endometrial cancer (aec): subgroup analysis of patients with DNA mismatch repair deficient (DMMR) tumors","authors":"V. Makker, N. Colombo, A. Casado Herráez, A. Santin, E. Colomba, D. Miller, K. Fujiwara, S. Pignata, Sri Banerjee, B. Monk, K. Ushijima, R. Penson, R. Kristeleit, M. Fabbro, M. Orlando, H. Mackay, M. Ren, R. Orlowski, L. Dutta, D. Lorusso","doi":"10.1136/ijgc-2021-igcs.2","DOIUrl":"https://doi.org/10.1136/ijgc-2021-igcs.2","url":null,"abstract":"","PeriodicalId":19692,"journal":{"name":"Oral abstracts","volume":"12 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78985034","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Oral abstractsPub Date : 2021-11-01DOI: 10.1136/ijgc-2021-igcs.17
Y. Gao, X. Wu, J. Zhu, R. Yin, J. Yang, J. Liu, J. Wang, L. Wu, Z. Liu, D. Wang, G. Lou, Hang Yang, Q. Zhou, B. Kong, Y. Huang, L. Chen, G. Li, R. An, T. Tan, J. Dong
{"title":"O017/#15 Efficacy and safety of niraparib maintenance treatment in platinum-sensitive recurrent ovarian cancer after shorter or longer chemotherapy: a post hoc subgroup analysis","authors":"Y. Gao, X. Wu, J. Zhu, R. Yin, J. Yang, J. Liu, J. Wang, L. Wu, Z. Liu, D. Wang, G. Lou, Hang Yang, Q. Zhou, B. Kong, Y. Huang, L. Chen, G. Li, R. An, T. Tan, J. Dong","doi":"10.1136/ijgc-2021-igcs.17","DOIUrl":"https://doi.org/10.1136/ijgc-2021-igcs.17","url":null,"abstract":"","PeriodicalId":19692,"journal":{"name":"Oral abstracts","volume":"26 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81195979","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Oral abstractsPub Date : 2021-11-01DOI: 10.1136/ijgc-2021-igcs.1
K. Tewari, B. Monk, I. Vergote, A. Miller, A. de Melo, H. Kim, Y. Kim, A. Lisyanskaya, V. Samouélian, D. Lorusso, F. Damian, C-L. Chang, E. Gotovkin, Shin-ichiro Takahashi, D. Ramone, J. Pikiel, J. Li, M. Mathias, M. Fury, A. Oaknin
{"title":"O001/#331 Empower-cervical 1/GOG-3016/ENGOT-CX9: results of phase 3 trial of cemiplimab vs investigator’s choice chemotherapy in recurrent/metastatic cervical carcinoma","authors":"K. Tewari, B. Monk, I. Vergote, A. Miller, A. de Melo, H. Kim, Y. Kim, A. Lisyanskaya, V. Samouélian, D. Lorusso, F. Damian, C-L. Chang, E. Gotovkin, Shin-ichiro Takahashi, D. Ramone, J. Pikiel, J. Li, M. Mathias, M. Fury, A. Oaknin","doi":"10.1136/ijgc-2021-igcs.1","DOIUrl":"https://doi.org/10.1136/ijgc-2021-igcs.1","url":null,"abstract":"","PeriodicalId":19692,"journal":{"name":"Oral abstracts","volume":"31 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76692310","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Oral abstractsPub Date : 2021-11-01DOI: 10.1136/ijgc-2021-igcs.4
P. Zola, G. Ciccone, R. Angioli, C. Terranova, E. Piovano, L. Fuso, D. di Cuonzo, E. Peirano, A. Perrone, V. Mandato, L. Zavallone, F. Chiudinelli, R. Berretta, S. Loda, S. Greggi, M. Adorni, E. Busato, G. Comerci, M. Fambrini, A. Ferrero
{"title":"O004/#393 Does intensive follow-up improve overall survivalin endometrial cancer patients? Results from the totem randomized controlled trial","authors":"P. Zola, G. Ciccone, R. Angioli, C. Terranova, E. Piovano, L. Fuso, D. di Cuonzo, E. Peirano, A. Perrone, V. Mandato, L. Zavallone, F. Chiudinelli, R. Berretta, S. Loda, S. Greggi, M. Adorni, E. Busato, G. Comerci, M. Fambrini, A. Ferrero","doi":"10.1136/ijgc-2021-igcs.4","DOIUrl":"https://doi.org/10.1136/ijgc-2021-igcs.4","url":null,"abstract":"","PeriodicalId":19692,"journal":{"name":"Oral abstracts","volume":"71 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91472932","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Oral abstractsPub Date : 2021-11-01DOI: 10.1136/ijgc-2021-igcs.13
B. Monk, T. Van Gorp, D. Lorusso, R. Eilish O’Cearbhaill, A. Westermann, Sri Banerjee, D. Collins, J. Klat, K. Madsen, J. Baurain, A. Jackson, I. Boere, S. Pignata, E. Gort, J. Moroney, I. Soumaoro, CM Andreassen, L. Nicacio, C. Gennigens, I. Vergote
{"title":"O013/#573 Tisotumab vedotin (TV) + bevacizumab or pembrolizumab or carboplatin in recurrent/metastatic cervical cancer (R/MCC): phase 1B/2 engot-CX8/GOG-3024/innovaTV 205 study dose-escalation results","authors":"B. Monk, T. Van Gorp, D. Lorusso, R. Eilish O’Cearbhaill, A. Westermann, Sri Banerjee, D. Collins, J. Klat, K. Madsen, J. Baurain, A. Jackson, I. Boere, S. Pignata, E. Gort, J. Moroney, I. Soumaoro, CM Andreassen, L. Nicacio, C. Gennigens, I. Vergote","doi":"10.1136/ijgc-2021-igcs.13","DOIUrl":"https://doi.org/10.1136/ijgc-2021-igcs.13","url":null,"abstract":"","PeriodicalId":19692,"journal":{"name":"Oral abstracts","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89542097","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Oral abstractsPub Date : 2021-10-01DOI: 10.1136/heartjnl-2021-ics.12
HM Sulaiman, P. Brennan, H. Connolly, J. McOsker, T. Jardine, A. Miur
{"title":"12 Comparison of slow vs. rapid ajmaline infusion protocol for the diagnosis of brugada syndrome (BrS): ten year experience of the Northern Ireland inherited cardiac conditions service (NI ICC)","authors":"HM Sulaiman, P. Brennan, H. Connolly, J. McOsker, T. Jardine, A. Miur","doi":"10.1136/heartjnl-2021-ics.12","DOIUrl":"https://doi.org/10.1136/heartjnl-2021-ics.12","url":null,"abstract":"12 Table 1 Demographics of patients by ajmaline challenge protocol Group A: Slow protocol (1mg/kg over 10 minutes) Group B: Rapid protocol (1mg/kg over 5 minutes) p-value No of tests, n (%) 251 (61%) 163 (39%) p=0.61 (ns) Age (mean ± sd) years 40 ± 16 43 ± 15 p=0.09 (ns) Gender (male: female) 136 : 115 75 : 88 p=0.10 (ns) Indications: a) Family History of BrS b) Family history of SADS/SUD c) History of OOHCA d) ECG abnormality e) Unexplained syncope 105 78 17","PeriodicalId":19692,"journal":{"name":"Oral abstracts","volume":"6 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75328949","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Oral abstractsPub Date : 2021-10-01DOI: 10.1136/heartjnl-2021-ics.13
N. Starr, S. Esmonde, N. McKEAG, E. Chew
{"title":"13 Long-term safety outcomes of patients implanted with subcutaneous implantable cardioverter defibrillators","authors":"N. Starr, S. Esmonde, N. McKEAG, E. Chew","doi":"10.1136/heartjnl-2021-ics.13","DOIUrl":"https://doi.org/10.1136/heartjnl-2021-ics.13","url":null,"abstract":"","PeriodicalId":19692,"journal":{"name":"Oral abstracts","volume":"111 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79311839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Oral abstractsPub Date : 2021-10-01DOI: 10.1136/heartjnl-2021-ics.8
H. Rai, F. Harzer, T. Otsuka, Y. Abdelwahed, P. Antuña, F. Blachutzik, T. Koppara, L. Räber, D. Leistner, F. Alfonso, H. Nef, M. Seguchi, A. Aytekin, E. Xhepa, S. Kufner, S. Cassese, K. Laugwitz, R. Byrne, A. Kastrati, M. Joner
{"title":"8 Stent optimization using optical coherence tomography and its prognostic implications after percutaneous coronary intervention","authors":"H. Rai, F. Harzer, T. Otsuka, Y. Abdelwahed, P. Antuña, F. Blachutzik, T. Koppara, L. Räber, D. Leistner, F. Alfonso, H. Nef, M. Seguchi, A. Aytekin, E. Xhepa, S. Kufner, S. Cassese, K. Laugwitz, R. Byrne, A. Kastrati, M. Joner","doi":"10.1136/heartjnl-2021-ics.8","DOIUrl":"https://doi.org/10.1136/heartjnl-2021-ics.8","url":null,"abstract":"","PeriodicalId":19692,"journal":{"name":"Oral abstracts","volume":"36 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89960562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Oral abstractsPub Date : 2021-10-01DOI: 10.1136/heartjnl-2021-ics.5
S. Saluja, H. Contractor, F. Mannan, Jadav Sarma, S. Garg, S. Anderson
{"title":"5 Comparison of next generation P2Y12 inhibitors to clopidogrel in patients with acute coronary syndrome: an analysis from the British cardiovascular intervention society database of 382,361 ‘real-world’ patients","authors":"S. Saluja, H. Contractor, F. Mannan, Jadav Sarma, S. Garg, S. Anderson","doi":"10.1136/heartjnl-2021-ics.5","DOIUrl":"https://doi.org/10.1136/heartjnl-2021-ics.5","url":null,"abstract":"genes DSG2, DSC2 and JUP. Conclusion Predictive testing has potentially allowed up to 789 genotype-negative individuals (and their offspring) to be reassured and discharged from long term cardiac follow-up. Our data suggests adult females are more forthcoming for predictive testing than their male counterparts. The absence of testing for several cardiomyopathy genes suggests low frequency or low penetrance of these variants in the Irish population. The large size of families in our cohort represents an opportunity to develop gene penetrance and genotype-phenotype correlation data to assist in clinical management of genotype-positive individuals.","PeriodicalId":19692,"journal":{"name":"Oral abstracts","volume":"25 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77566833","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Oral abstractsPub Date : 2021-10-01DOI: 10.1136/heartjnl-2021-ics.21
G. Keehan, A. Vainorius, A. White, A. Soo
{"title":"21 Surgical aortic valve replacement: earlier vs newer generation bioprosthetic valves – a comparison of early hemodynamic performance","authors":"G. Keehan, A. Vainorius, A. White, A. Soo","doi":"10.1136/heartjnl-2021-ics.21","DOIUrl":"https://doi.org/10.1136/heartjnl-2021-ics.21","url":null,"abstract":"","PeriodicalId":19692,"journal":{"name":"Oral abstracts","volume":"32 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78832437","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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