Onkologie最新文献

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Effect of immunotherapy and radiotherapy in the treatment of Merkel cell carcinoma in a patient with myelodysplastic syndrome 免疫治疗和放射治疗默克尔细胞癌合并骨髓增生异常综合征的疗效
4区 医学
Onkologie Pub Date : 2023-10-05 DOI: 10.36290/xon.2023.055
Miroslav Důra, Ivana Krajsová, Jolana Mertová
{"title":"Effect of immunotherapy and radiotherapy in the treatment of Merkel cell carcinoma in a patient with myelodysplastic syndrome","authors":"Miroslav Důra, Ivana Krajsová, Jolana Mertová","doi":"10.36290/xon.2023.055","DOIUrl":"https://doi.org/10.36290/xon.2023.055","url":null,"abstract":"","PeriodicalId":19684,"journal":{"name":"Onkologie","volume":"37 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135548394","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Brentuximab vedotin consolidation therapy after autologous stem cell transplantation in relapsed/refractory classic Hodgkin lymphoma patients in the Czech Republic Brentuximab vedotin在捷克共和国复发/难治性经典霍奇金淋巴瘤患者自体干细胞移植后的巩固治疗
4区 医学
Onkologie Pub Date : 2023-10-05 DOI: 10.36290/xon.2023.051
Jozef Michalka, Zdeněk Král, Jana Marková, Ľubica Gahérová, Mária Maco, Vít Procházka, Andrea Janíková, Jan Kořen, Alice Sýkorová, Pavla Štěpánková, Kateřina Steinerová, Lekaa Mohammad, Juraj Ďuraš, Barbora Velacková, Tomáš Doležal, Kateřina Benešová, Marie Lukášová, Heidi Móciková
{"title":"Brentuximab vedotin consolidation therapy after autologous stem cell transplantation in relapsed/refractory classic Hodgkin lymphoma patients in the Czech Republic","authors":"Jozef Michalka, Zdeněk Král, Jana Marková, Ľubica Gahérová, Mária Maco, Vít Procházka, Andrea Janíková, Jan Kořen, Alice Sýkorová, Pavla Štěpánková, Kateřina Steinerová, Lekaa Mohammad, Juraj Ďuraš, Barbora Velacková, Tomáš Doležal, Kateřina Benešová, Marie Lukášová, Heidi Móciková","doi":"10.36290/xon.2023.051","DOIUrl":"https://doi.org/10.36290/xon.2023.051","url":null,"abstract":"","PeriodicalId":19684,"journal":{"name":"Onkologie","volume":"302 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135548399","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The use of immunotherapy and targeted therapy in Richter's transformation 免疫治疗和靶向治疗在里希特氏变性中的应用
4区 医学
Onkologie Pub Date : 2023-10-05 DOI: 10.36290/xon.2023.053
Tereza Líkařová, Martin Špaček
{"title":"The use of immunotherapy and targeted therapy in Richter's transformation","authors":"Tereza Líkařová, Martin Špaček","doi":"10.36290/xon.2023.053","DOIUrl":"https://doi.org/10.36290/xon.2023.053","url":null,"abstract":"","PeriodicalId":19684,"journal":{"name":"Onkologie","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135548405","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Treatment of BRAF V600E-mutated metastatic colorectal cancer BRAF v600e突变的转移性结直肠癌的治疗
4区 医学
Onkologie Pub Date : 2023-10-05 DOI: 10.36290/xon.2023.044
Jiří Tomášek
{"title":"Treatment of BRAF V600E-mutated metastatic colorectal cancer","authors":"Jiří Tomášek","doi":"10.36290/xon.2023.044","DOIUrl":"https://doi.org/10.36290/xon.2023.044","url":null,"abstract":"","PeriodicalId":19684,"journal":{"name":"Onkologie","volume":"100 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135548417","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Options and rationale for reinstituting anti-EGFR therapy in pretreated RAS wild-type advanced colorectal carcinomas 在预先治疗的RAS野生型晚期结直肠癌中恢复抗egfr治疗的选择和理由
4区 医学
Onkologie Pub Date : 2023-10-05 DOI: 10.36290/xon.2023.045
Zdeněk Linke
{"title":"Options and rationale for reinstituting anti-EGFR therapy in pretreated RAS wild-type advanced colorectal carcinomas","authors":"Zdeněk Linke","doi":"10.36290/xon.2023.045","DOIUrl":"https://doi.org/10.36290/xon.2023.045","url":null,"abstract":"","PeriodicalId":19684,"journal":{"name":"Onkologie","volume":"7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135548393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Role of ruxolitinib in treatment of polycythemia vera 鲁索利替尼治疗真性红细胞增多症的作用
4区 医学
Onkologie Pub Date : 2023-10-05 DOI: 10.36290/xon.2023.048
Natália Podstavková
{"title":"Role of ruxolitinib in treatment of polycythemia vera","authors":"Natália Podstavková","doi":"10.36290/xon.2023.048","DOIUrl":"https://doi.org/10.36290/xon.2023.048","url":null,"abstract":"","PeriodicalId":19684,"journal":{"name":"Onkologie","volume":"25 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135548410","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Treatment of metastatic colorectal carcinoma - 3<sup>rd</sup> line and above 转移性结直肠癌的治疗- 3&lt;直线及以上
4区 医学
Onkologie Pub Date : 2023-10-05 DOI: 10.36290/xon.2023.046
Pavel Pacas, Adam Lukáč
{"title":"Treatment of metastatic colorectal carcinoma - 3&lt;sup&gt;rd&lt;/sup&gt; line and above","authors":"Pavel Pacas, Adam Lukáč","doi":"10.36290/xon.2023.046","DOIUrl":"https://doi.org/10.36290/xon.2023.046","url":null,"abstract":"","PeriodicalId":19684,"journal":{"name":"Onkologie","volume":"31 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135548420","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Targeted therapy: old and new possibilities]. [靶向治疗:新旧可能性]。
IF 0.3 4区 医学
Onkologie Pub Date : 2013-01-01 Epub Date: 2013-07-01 DOI: 10.1159/000351997
Andreas Hochhaus, Diana Lüftner, Andreas Mackensen
{"title":"[Targeted therapy: old and new possibilities].","authors":"Andreas Hochhaus,&nbsp;Diana Lüftner,&nbsp;Andreas Mackensen","doi":"10.1159/000351997","DOIUrl":"https://doi.org/10.1159/000351997","url":null,"abstract":"","PeriodicalId":19684,"journal":{"name":"Onkologie","volume":"36 Suppl 5 ","pages":"2-11"},"PeriodicalIF":0.3,"publicationDate":"2013-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000351997","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31638186","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Cancer patients and advance directives: a survey of patients in a hematology and oncology outpatient clinic. 癌症患者和预先指示:血液学和肿瘤学门诊患者的调查。
IF 0.3 4区 医学
Onkologie Pub Date : 2013-01-01 Epub Date: 2013-07-08 DOI: 10.1159/000353604
Elisabeth Hubert, Nadine Schulte, Sebastian Belle, Axel Gerhardt, Kirsten Merx, Wolf-Karsten Hofmann, Alexander Stein, Iris Burkholder, Ralf-Dieter Hofheinz, Melanie Kripp
{"title":"Cancer patients and advance directives: a survey of patients in a hematology and oncology outpatient clinic.","authors":"Elisabeth Hubert,&nbsp;Nadine Schulte,&nbsp;Sebastian Belle,&nbsp;Axel Gerhardt,&nbsp;Kirsten Merx,&nbsp;Wolf-Karsten Hofmann,&nbsp;Alexander Stein,&nbsp;Iris Burkholder,&nbsp;Ralf-Dieter Hofheinz,&nbsp;Melanie Kripp","doi":"10.1159/000353604","DOIUrl":"https://doi.org/10.1159/000353604","url":null,"abstract":"<p><strong>Background: </strong>In 2009, Germany enacted a new law supporting advance directives that led to heated discussions in the media and the public. 3 years after the law passed, we surveyed patients with malignant diseases with regards to their views on advance directives.</p><p><strong>Patients and methods: </strong>Between September 2011 and July 2012 an anonymous survey on advance directives was conducted among 617 patients at the hematology and oncology outpatient department of the University Hospital Mannheim, using a standardized questionnaire developed for this investigation.</p><p><strong>Results: </strong>Of the 503 patients who returned the questionnaire, 31% (n = 157) indicated having an advance directive. Of these 157, 54% (n = 85) completed the advance directive after 2009. 56% (282 out of 503) desired more information on advance directives. Of these, 71% (201 out of 282) wanted their general physician and 45% (128 out of 282) their specialist, to provide more information about this issue. Of the 339 patients without an advance directive, 47% (n = 158) stated that they had 'not worried about that yet'.</p><p><strong>Conclusion: </strong>Although the percentage of patients with advance directives has increased since the legislative amendment, more information is still required by patients. It is recommended that physicians should discuss advance directives more frequently with their patients.</p>","PeriodicalId":19684,"journal":{"name":"Onkologie","volume":"36 7-8","pages":"398-402"},"PeriodicalIF":0.3,"publicationDate":"2013-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000353604","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31638490","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 30
Concomitant chemoradiotherapy and antiretroviral therapy for HIV-infected patients with locoregionally advanced non-small cell lung cancer: benefit and tolerability of treatment in 2 cases. 联合放化疗和抗逆转录病毒治疗局部区域晚期非小细胞肺癌患者:2例治疗的获益和耐受性
IF 0.3 4区 医学
Onkologie Pub Date : 2013-01-01 Epub Date: 2013-09-17 DOI: 10.1159/000355162
Yusuke Okuma, Naoki Yanagisawa, Yukio Hosomi, Akifumi Imamura, Tatsuru Okamura, Kan Kato, Kyota Negishi
{"title":"Concomitant chemoradiotherapy and antiretroviral therapy for HIV-infected patients with locoregionally advanced non-small cell lung cancer: benefit and tolerability of treatment in 2 cases.","authors":"Yusuke Okuma,&nbsp;Naoki Yanagisawa,&nbsp;Yukio Hosomi,&nbsp;Akifumi Imamura,&nbsp;Tatsuru Okamura,&nbsp;Kan Kato,&nbsp;Kyota Negishi","doi":"10.1159/000355162","DOIUrl":"https://doi.org/10.1159/000355162","url":null,"abstract":"<p><strong>Background: </strong>Human immunodeficiency virus (HIV)-infected patients are surviving longer since the advent of antiretroviral therapy. Therefore, more patients are developing non-AIDS-defining cancers which increasingly determine mortality.</p><p><strong>Case reports: </strong>Here we present 2 cases of locally advanced non-small cell lung cancer treated initially with concomitant chemoradiotherapy and antiretroviral therapy. Both patients were male, ages 69 and 66, with known HIV infection and immunologically stable on antiretroviral therapy. Presenting symptoms included superior sulcus tumor with left arm immobility and sensory disturbance in case 1 and right lower bronchus constriction in case 2. Symptoms were controlled by chemoradiotherapy.</p><p><strong>Conclusion: </strong>These cases illustrate that intensive anticancer therapy administered to the HIV-infected population can be tolerated even though these patients seem to be too fragile for both chemotherapy and radiotherapy, especially since the potential benefit remains uncertain. Recent improvements in chemoradiotherapy and supportive care have enhanced tolerance for such therapy.</p>","PeriodicalId":19684,"journal":{"name":"Onkologie","volume":"36 10","pages":"586-90"},"PeriodicalIF":0.3,"publicationDate":"2013-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000355162","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31792073","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
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