{"title":"Recent Developments in Search of Effective Herbal Medicine for The Treatment of Leukemia","authors":"G. Shergill","doi":"10.33552/ojcam.2022.07.000659","DOIUrl":"https://doi.org/10.33552/ojcam.2022.07.000659","url":null,"abstract":"Leukemia is a group of malignant disorders characterized by abnormal leukocytes proliferation and development in the bone marrow and lymphatic system. It is the most prevalent hematologic cancer in adults above 55 years and the most common cancer in the pediatric population, accounting for nearly one-third of the cases. The five-year relative survival rates have enhanced over the years to 65.0% (2011-2017) through the application of therapeutic methodologies of standard chemotherapy. However, the prognosis of leukemia in geriatrics remains poor, with overall survival being only 5–10% in Acute Myeloid Leukemia (AML). Despite introducing new chemotherapeutic medications and hematopoietic stem cell transplantation, the events of cancer relapse, multi-drug resistance, suboptimal response, and severe adverse effects remain significant events for some patients. Thus, it is critical to investigate alternative treatment options with improved efficacy, reduced toxicity, and multitarget combinations of chemotherapeutic medications, maybe with distinct mechanisms involved, to optimize the outcome of leukemia patients. This review discusses the recently studied herbal medicines exhibiting potential apoptosis and anti-cancer effect on the leukemia cell lines. After using PubMed’s Advanced Search features with keywords such as “Herbal Medicine,” “Acute myeloid leukemia,” “Acute lymphocytic leukemia,” “Chronic myeloid leukemia,” “Chronic lymphocytic leukemia,” we refined our search with the publication date range from 2017-2021 and entered articles into this review. Study selection was made based on Cochrane library guidelines to arrive at 13 final articles selection, comprising nine different herbs. The study details underlying mechanisms governing their anti-cancer effects, and corresponding biological effects.","PeriodicalId":19661,"journal":{"name":"Online Journal of Complementary & Alternative Medicine","volume":"166 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80452166","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Evaluating the Effectiveness of Nutritional Therapy in the McClelland Teaching Clinic at the University of Worcester","authors":"Miranda D Harris","doi":"10.33552/ojcam.2021.06.000637","DOIUrl":"https://doi.org/10.33552/ojcam.2021.06.000637","url":null,"abstract":"Introduction: NT is an evidence-based complementary therapy, which applies nutrition and lifestyle science to underlying pathophysiology, resulting in personalized health improvement advice. Efficacy depends on establishing a quality relationship between therapist and client. The aim of the pilot study was to measure the effectiveness of NT at the UoW teaching clinic using the Working Alliance Inventory-Short Revised (WAI-SR) and a symptom-specific outcome measure, Measure Yourself Medical Outcome Profile 2 (MYMOP2). Methods: The interventional, before-and-after, within group pilot study used MYMOP2 to evaluate client symptoms, activity and wellbeing, and WAI-SR to evaluate therapist and client working relationship. Fifty-five clients and 22 students participated. Measures were taken at initial and follow-up consultation. Twenty completed measures were statistically analyzed using non-parametric tests. Clients presented with a range of symptoms, particularly digestive issues (27.3%) and low energy (20%). A statistically significant improvement was seen in Symptom 1 (z=-3.69, p<.001, r=.82), Symptom 2 (z=-3.32, p<.001, r=.74), Activity (z=-2.07, p<.001, r=.7), WAI-SRT (z=3.18, p<.05, r=.7) and WAI-SRC (z=2.19, p<.001, r=.5) with large effect sizes, and no significant improvement in Wellbeing. Strong, positive relationships were found between combined Symptom 1 and Activity, and Wellbeing at initial (r=.5, n=20, p<.05) and follow-up (r=.6, n=20, p<.05). A strong therapist and client working alliance was evident at initial and follow-up consultation. Conclusion: Preliminary results suggest NT practice is effective in reducing client symptoms and improving health and activity. This may be facilitated by a strong therapist and client working alliance. Further larger-scaled research would support findings with more robust analysis.","PeriodicalId":19661,"journal":{"name":"Online Journal of Complementary & Alternative Medicine","volume":"11 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82272549","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Case Report on Acupuncture Treating Wilson Disease","authors":"F. Liang","doi":"10.33552/ojcam.2021.05.000624","DOIUrl":"https://doi.org/10.33552/ojcam.2021.05.000624","url":null,"abstract":"Wilson disease (WD), an autosomal recessive disease with abnormal copper metabolism, is caused by mutations in the ATP7B gene. It is characterized by liver, nervous system, and ocular manifestations related to the deposition of copper in the liver, lens nucleus, and cornea. The case reported in this article was a 30-year-old woman with high muscle tension, unable to stand or walk, low voice, and short-term memory loss. Brain MRI showed patchy T1, long T2 signals, and high FLAIR showed signals in the basal ganglia thalamus area, subcortex, and brain stem. Low signal shadows were presented in magnetically sensitive bilateral basal ganglia region, callus, and cerebellar dentate nucleus. Ceruloplasmin was significantly reduced. With conventional treatment by western medicine, the symptoms were not alleviated. However, after the application of acupuncture-assisted treatment, the patient is capable with self-care ability, thus a desired effect was achieved. It is therefore suggested that acupuncture shall be applied to assist treatment of WD to relieve symptoms and help patients return to the society.","PeriodicalId":19661,"journal":{"name":"Online Journal of Complementary & Alternative Medicine","volume":"16 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-02-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84984833","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Need for a Deeper Notion of Holism in Complementary and Alternative Medicine","authors":"Hans A Baer","doi":"10.33552/ojcam.2021.05.000625","DOIUrl":"https://doi.org/10.33552/ojcam.2021.05.000625","url":null,"abstract":"I am writing this opinion piece from my perspective as a critical health and ecological anthropologist who has grappled since around 1980 with various CAM systems, particularly osteopathy, chiropractic, naturopathy, Chinese medicine, in the US, UK, and Australia, and more recently since 2005 with anthropogenic climate change. Both CAM and critical health anthropology are committed to the notion of holistic health and perhaps even planetary health, albeit in different ways. In reality, CAM is an amorphous category created by progressive biomedical physicians responding to the growing popularity of a wide array of alternative or heterodox health medical systems which found common cause under the umbrella of the holistic health movement in the 1970s [1]. Integrative medicine also arose as a biomedical construction to supposedly blend the best elements of biomedicine and CAM and also adopted the notion of holism, but some would argue to co-opt various CAM systems [2,3]. What is desperately needed is an examination of how the various CAM systems define holistic health and health care. Nevertheless, my sense in having examined various CAM systems and medical pluralism for four decades is that CAM practitioners tend to view holism in terms of making mind-body-spirit connections, but often tend to either neglect or downplay the role of political, economic, and social structural, and environmental factors in disease etiology. Needless to say, there are exceptions to his observations. For example, the School of Natural and Complementary Medicine at Southern Cross University in Australia developed a Basic Model of (W)holistic Medicine in 1999 which recognises six elements in whole-person care: (1) physical, (2) mental, (3), spiritual, (4) family, (5) community, and (6) environment [4].","PeriodicalId":19661,"journal":{"name":"Online Journal of Complementary & Alternative Medicine","volume":"24 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-02-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90103355","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Experience of Integrative Medicine in the Hospice Ward of the University Hospital San Martino in Genoa, Italy","authors":"N. Traverso","doi":"10.33552/ojcam.2021.05.000623","DOIUrl":"https://doi.org/10.33552/ojcam.2021.05.000623","url":null,"abstract":"Nicola Traverso1*, Stefano Bartoldi2, Davide Ferrari3, Cristina Bazzan4 and Michele Gallucci5 1Associate Professor in Clinical Pathology, University of Genova, Italy 2Thesis Student, Degree Course in Medicine and Surgery, University of Genova, Italy 3Music Therapist, IRCCS University Hospital San Martino, Genova, Italy 4Art Therapist, IRCCS University Hospital San Martino, Genova, Italy 5Head Physician of the Hospice Ward, IRCCS University Hospital San Martino, Genova, Italy ISSN: 2644-2957 DOI: 10.33552/OJCAM.2021.05.000623","PeriodicalId":19661,"journal":{"name":"Online Journal of Complementary & Alternative Medicine","volume":"275 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-02-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76382251","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comprehensive Role of Otorhinolaryngologists in the Management of Headache: A Prospective Tertiary Care Centre Based Study","authors":"Rajwant Kaur Kamal","doi":"10.33552/ojcam.2021.05.000622","DOIUrl":"https://doi.org/10.33552/ojcam.2021.05.000622","url":null,"abstract":"","PeriodicalId":19661,"journal":{"name":"Online Journal of Complementary & Alternative Medicine","volume":"8 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81712572","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Medicinal Uses of Juniper Tree Cones","authors":"L. El-Juhany","doi":"10.33552/ojcam.2021.05.000621","DOIUrl":"https://doi.org/10.33552/ojcam.2021.05.000621","url":null,"abstract":"","PeriodicalId":19661,"journal":{"name":"Online Journal of Complementary & Alternative Medicine","volume":"31 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74422411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"From Evidence to Practice: Importance of Developing Guidelines for Clinical Practice in Migraine Prophylaxis with Acupuncture","authors":"Yemeng Chen","doi":"10.33552/OJCAM.2021.05.000619","DOIUrl":"https://doi.org/10.33552/OJCAM.2021.05.000619","url":null,"abstract":"In acupuncture practice, emphasis was focused on episodic migraine treatment, but the evidence-based practice revealed that acupuncture in migraine prophylaxis is superior to conventional medicine which is significant to clinical practice. Body constitution, syndrome differentiation, acupoints selection, needle techniques, stimulation modality, and treatment plan are the factors to be considered for developing guidelines of clinical practice for acupuncture in migraine prophylaxis.","PeriodicalId":19661,"journal":{"name":"Online Journal of Complementary & Alternative Medicine","volume":"26 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84989888","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Perspective: Has Masking, Hand Washing, Distancing and Sheltering in Place for the COVID-19 Pandemic Adequately Addressed Immunity?","authors":"N. Byl","doi":"10.33552/OJCAM.2021.05.000617","DOIUrl":"https://doi.org/10.33552/OJCAM.2021.05.000617","url":null,"abstract":"Around the world, 2020 will be remembered as the year challenged by the coronavirus. Some people continue to ask: “Is the coronavirus really that serious?” If casinos, theaters and churches are closed, heaven and hell have apparently agreed on the same thing: the coronavirus is serious! Despite the early warnings in China in December of 2019, the United States was not successful in reducing the incidence, prevalence or fatalities due to COVID 19. Guidelines to wear masks, maintain 6-foot distancing, hand washing to sheltering in place did not stop the spread of the coronavirus, minimize the fatality rate nor decrease the demand on our Intensive Care Units [1-4]. Further the guidelines have not directly addressed immunity nor provided insight to distinguish those who would suffer severe disease, sustain fatal effects or survive with minimal or severe impairments [5-7].","PeriodicalId":19661,"journal":{"name":"Online Journal of Complementary & Alternative Medicine","volume":"43 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77141053","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Fearing the Future: A Call to Teach Hope","authors":"K. Richards","doi":"10.33552/OJCAM.2021.05.000616","DOIUrl":"https://doi.org/10.33552/OJCAM.2021.05.000616","url":null,"abstract":"Evaluation of the level of hope in interprofessional students, before the COVID-19 pandemic hit, included: temporality and future; positive readiness and expectancy; and interconnectedness with self and others as well as an overall score of hope. With a total possible score of 48, indicating the maximum level of hope, scores ranged from 30-41. This study identified that while 85% of the participants indicated that had both short and long-term goals, 39% of the participants still felt all alone. Schools cannot neglect the vital component of hope. All higher education healthcare professionals can deviate to developing interventions and curriculum to address hope, specifically the fear of the future and lack of inner strength among our students.","PeriodicalId":19661,"journal":{"name":"Online Journal of Complementary & Alternative Medicine","volume":"120 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90573403","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}