Origins of Life and Evolution of Biospheres最新文献_第7页

Unexpected Thiocyanate Adsorption onto Ferrihydrite Under Prebiotic Chemistry Conditions. 在益生元化学条件下硫氰酸盐在水合铁上的意外吸附。

IF 2 4区物理与天体物理

Origins of Life and Evolution of Biospheres Pub Date : 2020-06-01 Epub Date: 2020-04-07 DOI: 10.1007/s11084-020-09594-w

Dimas A M Zaia, Paulo C G de Carvalho, Rafael B Samulewski, Rodrigo de Carvalho Pereira, Cássia Thaïs B V Zaia

{"title":"Unexpected Thiocyanate Adsorption onto Ferrihydrite Under Prebiotic Chemistry Conditions.","authors":"Dimas A M Zaia, Paulo C G de Carvalho, Rafael B Samulewski, Rodrigo de Carvalho Pereira, Cássia Thaïs B V Zaia","doi":"10.1007/s11084-020-09594-w","DOIUrl":"https://doi.org/10.1007/s11084-020-09594-w","url":null,"abstract":"The most crucial role played by minerals was in the preconcentration of biomolecules or precursors of biomolecules in prebiotic seas. If this step had not occurred, molecular evolution would not have occurred. Thiocyanate is an important molecule in the formation of biomolecules as well as a catalyst for prebiotic reactions. The adsorption of thiocyanate onto ferrihydrite was carried out under pH and ion composition conditions in seawater that resembled those of prebiotic Earth. The seawater used in this work had high Mg2+, Ca2+ and SO42- concentrations. The most important result of this work was that ferrihydrite adsorbed thiocyanateata pH value (7.2 ± 0.2) that usually does not adsorb thiocyanate. The high adsorptivity of Mg2+, Ca2+ and SO42-onto ferrihydrite showed that seawater ions can act as carriers of thiocyanate to the ferrihydrite surface, creating a huge outer-sphere complex. Kinetic adsorption and isotherm experiments showed the best fit for the pseudo-second-order model and an activation energy of 23.8 kJ mol-1forthe Langmuir-Freundlich model, respectively. Thermodynamic data showed positive ΔG values, which apparently contradict the adsorption isotherm data and kinetic data that was obtained. The adsorption of thiocyanate onto ferrihydrite could be explained by coupling with the exergonic SO42- adsorption onto ferrihydrite. The FTIR spectra showed no difference between the C≡N stretching peaks of adsorbed thiocyanate and free thiocyanate, corroborating the formation of an outer-sphere complex. All the results demonstrated the importance of the artificial seawater composition for the adsorption of thiocyanate and for understanding prebiotic chemistry.","PeriodicalId":19614,"journal":{"name":"Origins of Life and Evolution of Biospheres","volume":"50 1-2","pages":"57-76"},"PeriodicalIF":2.0,"publicationDate":"2020-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s11084-020-09594-w","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37815208","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 10

The Prebiotic Provenance of Semi-Aqueous Solvents. 半水溶剂的益生元来源。

IF 2 4区物理与天体物理

Origins of Life and Evolution of Biospheres Pub Date : 2020-06-01 Epub Date: 2020-05-09 DOI: 10.1007/s11084-020-09595-9

Jennifer L Lago, Bradley T Burcar, Nicholas V Hud, Rio Febrian, Christopher Mehta, Paul J Bracher, Zachary D Atlas, Matthew A Pasek

{"title":"The Prebiotic Provenance of Semi-Aqueous Solvents.","authors":"Jennifer L Lago, Bradley T Burcar, Nicholas V Hud, Rio Febrian, Christopher Mehta, Paul J Bracher, Zachary D Atlas, Matthew A Pasek","doi":"10.1007/s11084-020-09595-9","DOIUrl":"https://doi.org/10.1007/s11084-020-09595-9","url":null,"abstract":"The numerous and varied roles of phosphorylated organic molecules in biochemistry suggest they may have been important to the origin of life. The prominence of phosphorylated molecules presents a conundrum given that phosphorylation is a thermodynamically unfavorable, endergonic process in water, and most natural sources of phosphate are poorly soluble. We recently demonstrated that a semi-aqueous solvent consisting of urea, ammonium formate, and water (UAFW) supports the dissolution of phosphate and the phosphorylation of nucleosides. However, the prebiotic feasibility and robustness of the UAFW system are unclear. Here, we study the UAFW system as a medium in which phosphate minerals are potentially solubilized. Specifically, we conduct a series of chemical experiments alongside thermodynamic models that simulate the formation of ammonium formate from the hydrolysis of hydrogen cyanide, and demonstrate the stability of formamide in such solvents (as an aqueous mixture). The dissolution of hydroxylapatite requires a liquid medium, and we investigate whether a UAFW system is solid or liquid over varied conditions, finding that this characteristic is controlled by the molar ratios of the three components. For liquid UAFW mixtures, we also find the solubility of phosphate is higher when the quantity of ammonium formate is greater than urea. We suggest the urea within the system can lower the activity of water, help create a stable and persistent solution, and may act as a condensing agent/catalyst to improve nucleoside phosphorylation yields.","PeriodicalId":19614,"journal":{"name":"Origins of Life and Evolution of Biospheres","volume":"50 1-2","pages":"1-14"},"PeriodicalIF":2.0,"publicationDate":"2020-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s11084-020-09595-9","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37918690","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 9

Chirality Driven Twisting as a Driving Force of Primitive Folding in Binary Mixtures. 手性驱动扭转作为二元混合物原始折叠的驱动力。

IF 2 4区物理与天体物理

Origins of Life and Evolution of Biospheres Pub Date : 2020-06-01 Epub Date: 2020-04-30 DOI: 10.1007/s11084-020-09596-8

Dmitry V Zlenko, Aleksey A Skoblin, Alexander S Vedenkin, Mariya G Mikhaleva, Anatoly M Zanin, Vsevolod A Tverdislov, Sergey V Stovbun

{"title":"Chirality Driven Twisting as a Driving Force of Primitive Folding in Binary Mixtures.","authors":"Dmitry V Zlenko, Aleksey A Skoblin, Alexander S Vedenkin, Mariya G Mikhaleva, Anatoly M Zanin, Vsevolod A Tverdislov, Sergey V Stovbun","doi":"10.1007/s11084-020-09596-8","DOIUrl":"https://doi.org/10.1007/s11084-020-09596-8","url":null,"abstract":"The N-trifluoroacetylated α-aminoalcohols (TFAAAs) are able to form quasi-one-dimensional supramolecular fibers (strings) when chirally pure, and isometric precipitates in the racemate. The strings' formation leads to the reversible gelation of the solution. The fresh gels occupy all the available volume, however during the incubation, they contract and concentrate in the central region of the tube. The microscopic observations revealed the growth of the strings' diameter and their rotation in the course of the incubation at the hour time-scale. The rotation provides for the hairpins forming that serve as hooks on the rotating string, which provides for coiling of the strings, which was observed as gel contraction. The morphology of the twisted strings resembles the structures observed in modern proteins, which allows drawing an analogy between the folding of biopolymers and the formation of the clew of strings. In addition, the rotation found in the TFAAA gels is an example of a simple system converting the energy of intermolecular agglutination to the rotational movement, so they could be considered as molecular motors.","PeriodicalId":19614,"journal":{"name":"Origins of Life and Evolution of Biospheres","volume":"50 1-2","pages":"77-86"},"PeriodicalIF":2.0,"publicationDate":"2020-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s11084-020-09596-8","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37885617","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Alteration and Stability of Complex Macromolecular Amino Acid Precursors in Hydrothermal Environments. 水热环境中复杂大分子氨基酸前体的改变和稳定性。

IF 2 4区物理与天体物理

Origins of Life and Evolution of Biospheres Pub Date : 2020-06-01 Epub Date: 2020-04-20 DOI: 10.1007/s11084-020-09593-x

Walaa Elmasry, Yoko Kebukawa, Takeo Kaneko, Yumiko Obayashi, Hitoshi Fukuda, Yoshiyuki Oguri, Kensei Kobayashi

{"title":"Alteration and Stability of Complex Macromolecular Amino Acid Precursors in Hydrothermal Environments.","authors":"Walaa Elmasry, Yoko Kebukawa, Takeo Kaneko, Yumiko Obayashi, Hitoshi Fukuda, Yoshiyuki Oguri, Kensei Kobayashi","doi":"10.1007/s11084-020-09593-x","DOIUrl":"https://doi.org/10.1007/s11084-020-09593-x","url":null,"abstract":"The early Solar System comprised a broad area of abiotically created organic compounds, including interstellar organics which were integrated into planetesimals and parent bodies of meteorites, and eventually delivered to the early Earth. In this study, we simulated interstellar complex organic compounds synthesized by proton irradiation of a gas mixture of CO, NH3, and H2O, which are known to release amino acids after acid hydrolysis on the basis of Kobayashi et al. (1999) who reported that at the first stage of chemical evolution, the main compounds formed abiotically are complex organic compounds with high molecular weights. We examined their possible hydrothermal alteration and stabilities as amino acid precursors under high temperature and pressure conditions simulating parent bodies of meteorites by using an autoclave. We reported that all samples treated at 200-300 °C predominantly released glycine and alanine, followed by α-aminobutyric acid, and serine. After heating, amino acid concentrations decreased in general; however, the recovery ratios of γ-aminobutyric acid increased with temperature. The interstellar complex organic analog could maintain as amino acid precursors after being treated at high temperature (200-300 °C) and pressure (8-14 MPa). However, the molecular structures were altered during heating to form organic compounds that are more stable and can survive in elevated hydrothermal conditions.","PeriodicalId":19614,"journal":{"name":"Origins of Life and Evolution of Biospheres","volume":"50 1-2","pages":"15-33"},"PeriodicalIF":2.0,"publicationDate":"2020-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s11084-020-09593-x","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37854089","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

On A Hypothetical Mechanism of Interstellar Life Transfer Trough Nomadic Objects. 星际生命通过游牧天体转移的假设机制。

IF 2 4区物理与天体物理

Origins of Life and Evolution of Biospheres Pub Date : 2020-06-01 Epub Date: 2020-02-07 DOI: 10.1007/s11084-020-09591-z

Grzegorz Sadlok

引用次数: 6

Reactivity of Metabolic Intermediates and Cofactor Stability under Model Early Earth Conditions. 模型早期地球条件下代谢中间体的反应性和辅因子稳定性。

IF 2 4区物理与天体物理

Origins of Life and Evolution of Biospheres Pub Date : 2020-06-01 Epub Date: 2020-01-25 DOI: 10.1007/s11084-019-09590-9

Thora R Maltais, David VanderVelde, Douglas E LaRowe, Aaron D Goldman, Laura M Barge

{"title":"Reactivity of Metabolic Intermediates and Cofactor Stability under Model Early Earth Conditions.","authors":"Thora R Maltais, David VanderVelde, Douglas E LaRowe, Aaron D Goldman, Laura M Barge","doi":"10.1007/s11084-019-09590-9","DOIUrl":"https://doi.org/10.1007/s11084-019-09590-9","url":null,"abstract":"Understanding the emergence of metabolic pathways is key to unraveling the factors that promoted the origin of life. One popular view is that protein cofactors acted as catalysts prior to the evolution of the protein enzymes with which they are now associated. We investigated the stability of acetyl coenzyme A (Acetyl Co-A, the group transfer cofactor in citric acid synthesis in the TCA cycle) under early Earth conditions, as well as whether Acetyl Co-A or its small molecule analogs thioacetate or acetate can catalyze the transfer of an acetyl group onto oxaloacetate in the absence of the citrate synthase enzyme. Several different temperatures, pH ranges, and compositions of aqueous environments were tested to simulate the Earth's early ocean and its possible components; the effect of these variables on oxaloacetate and cofactor chemistry were assessed under ambient and anoxic conditions. The cofactors tested are chemically stable under early Earth conditions, but none of the three compounds (Acetyl Co-A, thioacetate, or acetate) promoted synthesis of citric acid from oxaloacetate under the conditions tested. Oxaloacetate reacted with itself and/or decomposed to form a sequence of other products under ambient conditions, and under anoxic conditions was more stable; under ambient conditions the specific chemical pathways observed depended on the environmental conditions such as pH and presence/absence of bicarbonate or salt ions in early Earth ocean simulants. This work demonstrates the stability of these metabolic intermediates under anoxic conditions. However, even though free cofactors may be stable in a geological environmental setting, an enzyme or other mechanism to promote reaction specificity would likely be necessary for at least this particular reaction to proceed.","PeriodicalId":19614,"journal":{"name":"Origins of Life and Evolution of Biospheres","volume":"50 1-2","pages":"35-55"},"PeriodicalIF":2.0,"publicationDate":"2020-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s11084-019-09590-9","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37578965","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 7

Symphony in C: Carbon and the Evolution of (Almost) Everything by Robert M. Hazen, W.W. Norton & Company, 2019 《C调交响曲:碳与(几乎)万物的进化》，罗伯特·m·哈森著，W.W.诺顿公司，2019年

IF 2 4区物理与天体物理

Origins of Life and Evolution of Biospheres Pub Date : 2020-02-13 DOI: 10.1007/s11084-020-09592-y

P. Bahn

引用次数: 3

Membranes Composed of Lipopeptides and Liponucleobases Inspired Protolife Evolution. 由脂肽和脂核酸组成的薄膜启发了原生生物进化

IF 2 4区物理与天体物理

Origins of Life and Evolution of Biospheres Pub Date : 2019-12-01 Epub Date: 2019-12-27 DOI: 10.1007/s11084-019-09587-4

Gordon D Sproul

{"title":"Membranes Composed of Lipopeptides and Liponucleobases Inspired Protolife Evolution.","authors":"Gordon D Sproul","doi":"10.1007/s11084-019-09587-4","DOIUrl":"10.1007/s11084-019-09587-4","url":null,"abstract":"Amino acids and peptides have been demonstrated to form lipoamino acids and lipopeptides under presumed prebiotic conditions, and readily form liposomes. Of the common nucleobases, adenine forms a liponucleobase even below 100 °C. Adenine as well as other nucleobases can also be derivatized with ethylene carbonate (and likely other similar compounds) onto which fatty acids can be attached. The fatty acid tails along with appropriately functionalized nucleobases provide some solubility of liponucleobases in membranes. Such membranes would provide a structure in which three of biology's major components are closely associated and available for chemical interactions. Nucleobase-to-nucleobase interactions would ensure that the liponucleobases would have a uniquely different head-group relationship than other amphiphiles within a membrane, likely forming rafts due their π-π interactions and providing surface discontinuities that could serve as catalytic sites. The π-π bond distance in aromatic compounds is typically 0.34 nm, commensurate with that of the amine to carboxylate distance in alpha amino acids. This would have provided opportunity for hydrogen bonding between amino acids and the distal primary amines or tautomeric carbonyl/hydroxyl groups of two π-bonded nucleobases. Such bonding would weaken the covalent linkages within the amino acids, making them susceptible to forming peptide bonds with an adjacent amino acid, likely a lipoamino acid or lipopeptide. Were this second lipoamino acid bound to a third π-bonded nucleobase, it could result in orientation, destabilization and peptide formation. The stacked triplet of nucleobases might constitute the primordial codon triplet from which peptides were synthesized: primordial translation.","PeriodicalId":19614,"journal":{"name":"Origins of Life and Evolution of Biospheres","volume":"49 4","pages":"241-254"},"PeriodicalIF":2.0,"publicationDate":"2019-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s11084-019-09587-4","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37496477","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Carbonyl Sulfide as a Prebiotic Activation Agent for Stereo- and Sequence-Selective, Amyloid-Templated Peptide Elongation. 羰基硫化物作为立体和序列选择性淀粉样蛋白诱导肽延伸的前生物活化剂。

IF 2 4区物理与天体物理

Origins of Life and Evolution of Biospheres Pub Date : 2019-12-01 Epub Date: 2019-12-16 DOI: 10.1007/s11084-019-09586-5

Radoslaw Bomba, Saroj K Rout, Matthias Bütikofer, Witek Kwiatkowski, Roland Riek, Jason Greenwald

引用次数: 2

ASTROBIOLOGY AND HUMANISM: Conversations on Science, Philosophy and Theology by Julian Chela-Flores, Cambridge Scholars Publishing, 2019 天体生物学与人文主义:科学、哲学和神学对话，朱利安·切拉-弗洛雷斯著，剑桥学者出版社，2019年

IF 2 4区物理与天体物理

Origins of Life and Evolution of Biospheres Pub Date : 2019-08-08 DOI: 10.1007/s11084-019-09584-7

P. Bahn

引用次数: 1