Origins of Life and Evolution of Biospheres最新文献_第4页

A Cofactor-Based Mechanism for the Origin of the Genetic Code. 基于协因子的遗传密码起源机制。

IF 2 4区物理与天体物理

Origins of Life and Evolution of Biospheres Pub Date : 2022-09-01 Epub Date: 2022-09-08 DOI: 10.1007/s11084-022-09628-5

Juan A Martínez Giménez, Rafael Tabares Seisdedos

{"title":"A Cofactor-Based Mechanism for the Origin of the Genetic Code.","authors":"Juan A Martínez Giménez, Rafael Tabares Seisdedos","doi":"10.1007/s11084-022-09628-5","DOIUrl":"https://doi.org/10.1007/s11084-022-09628-5","url":null,"abstract":"The origin of the genetic code is probably the central problem of the studies on the origin of life. The key question to answer is the molecular mechanism that allows the association of the amino acids with their triplet codons. We proposed that the codon-anticodon duplex located in the acceptor stem of primitive tRNAs would facilitate the chemical reactions required to synthesize cognate amino acids from simple amino acids (glycine, valine, and aspartic acid) linked to the 3' acceptor end. In our view, various nucleotide-A-derived cofactors (with reactive chemical groups) may be attached to the codon-anticodon duplex, which allows group-transferring reactions from cofactors to simple amino acids, thereby producing the final amino acid. The nucleotide-A-derived cofactors could be incorporated into the RNA duplex (helix) by docking Adenosine (cofactor) into the minor groove via an interaction similar to the A-minor motif, forming a base triple between Adenosine and one complementary base pair of the duplex. Furthermore, we propose that this codon-anticodon duplex could initially catalyze a self-aminoacylation reaction with a simple amino acid. Therefore, the sequence of bases in the codon-anticodon duplex would determine the reactions that occurred during the formation of new amino acids for selective binding of nucleotide-A-derived cofactors.","PeriodicalId":19614,"journal":{"name":"Origins of Life and Evolution of Biospheres","volume":null,"pages":null},"PeriodicalIF":2.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33447361","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Asymmetric Autocatalysis as an Efficient Link Between the Origin of Homochirality and Highly Enantioenriched Compounds. 不对称自催化是同手性和高对映体富集化合物的有效联系。

IF 2 4区物理与天体物理

Origins of Life and Evolution of Biospheres Pub Date : 2022-09-01 Epub Date: 2022-08-12 DOI: 10.1007/s11084-022-09626-7

Kenso Soai, Tsuneomi Kawasaki, Arimasa Matsumoto

引用次数: 0

Introduction to Origins of Biological Homochirality. 生物同手性起源导论。

IF 2 4区物理与天体物理

Origins of Life and Evolution of Biospheres Pub Date : 2022-09-01 DOI: 10.1007/s11084-022-09629-4

Axel Brandenburg, David Hochberg

引用次数: 1

Competitive interaction of Mn(II) and Fe(II) cations with the high-affinity Mn-binding site of the photosystem II: evolutionary aspect. Mn(II)和Fe(II)阳离子与光系统II高亲和力Mn结合位点的竞争相互作用:进化方面的研究。

IF 2 4区物理与天体物理

Origins of Life and Evolution of Biospheres Pub Date : 2022-09-01 Epub Date: 2022-07-07 DOI: 10.1007/s11084-022-09625-8

E R Lovyagina, B К Semin

{"title":"Competitive interaction of Mn(II) and Fe(II) cations with the high-affinity Mn-binding site of the photosystem II: evolutionary aspect.","authors":"E R Lovyagina, B К Semin","doi":"10.1007/s11084-022-09625-8","DOIUrl":"https://doi.org/10.1007/s11084-022-09625-8","url":null,"abstract":"The evolutionary origin of the oxygen-evolving complex (OEC) in the photosystem II (PSII) is still unclear, as is the nature of electron source for the photosystem before the OEC had appeared. Johnson et al. (in PNAS 110:11238, 2013) speculated that Mn(II) cations were the source of electrons for transitional photosystems. However, Archean oceans also contained Fe(II) cations at concentrations comparable or higher than that of Mn(II). Fe(II) cations can bind to the high-affinity (НА) Mn-binding site in the OEC (Semin et al. in Biochemistry 41:5854, 2002). Now we have investigated the competitive interaction of Mn(II) and Fe(II) cations with the HA site in the Mn-depleted PSII membranes (PSII[-Mn]). Fe cations, oxidized under illumination, bind strongly to the HA site and, thus, prevent the interaction of Mn(II) with this site. If the Mn(II) and Fe(II) cations, at relatively equal concentration, are simultaneously present in the buffer, together with PSII(-Mn) membranes, there is competition between these two cations for the binding site, which manifests itself in partial inhibition of the Mn(II) oxidation and the blocking of the HA site by Fe(II) cations. If the concentration of Fe(II) cations is several times higher than the concentration of Mn(II), the HA site is completely blocked and the oxidation of Mn(II) cations is inhibited; under saturating light, the effectiveness of this inhibitory effect increases. This may be due to the generation of H2O2 on the acceptor side of the photosystem, which significantly accelerates the rate of the turnover reaction of Mn(II) on the HA site.","PeriodicalId":19614,"journal":{"name":"Origins of Life and Evolution of Biospheres","volume":null,"pages":null},"PeriodicalIF":2.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40567042","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Frontiers in Prebiotic Chemistry and Early Earth Environments. 生命前化学与早期地球环境的前沿。

IF 2 4区物理与天体物理

Origins of Life and Evolution of Biospheres Pub Date : 2022-09-01 Epub Date: 2022-07-07 DOI: 10.1007/s11084-022-09622-x

Ulrich F Müller, Jamie Elsila, Dustin Trail, Saurja DasGupta, Claudia-Corina Giese, Craig R Walton, Zachary R Cohen, Tomislav Stolar, Ramanarayanan Krishnamurthy, Timothy W Lyons, Karyn L Rogers, Loren Dean Williams

{"title":"Frontiers in Prebiotic Chemistry and Early Earth Environments.","authors":"Ulrich F Müller, Jamie Elsila, Dustin Trail, Saurja DasGupta, Claudia-Corina Giese, Craig R Walton, Zachary R Cohen, Tomislav Stolar, Ramanarayanan Krishnamurthy, Timothy W Lyons, Karyn L Rogers, Loren Dean Williams","doi":"10.1007/s11084-022-09622-x","DOIUrl":"https://doi.org/10.1007/s11084-022-09622-x","url":null,"abstract":"The Prebiotic Chemistry and Early Earth Environments (PCE3) Consortium is a community of researchers seeking to understand the origins of life on Earth and in the universe. PCE3 is one of five Research Coordination Networks (RCNs) within NASA's Astrobiology Program. Here we report on the inaugural PCE3 workshop, intended to cross-pollinate, transfer information, promote cooperation, break down disciplinary barriers, identify new directions, and foster collaborations. This workshop, entitled, \"Building a New Foundation\", was designed to propagate current knowledge, identify possibilities for multidisciplinary collaboration, and ultimately define paths for future collaborations. Presentations addressed the likely conditions on early Earth in ways that could be incorporated into prebiotic chemistry experiments and conceptual models to improve their plausibility and accuracy. Additionally, the discussions that followed among workshop participants helped to identify within each subdiscipline particularly impactful new research directions. At its core, the foundational knowledge base presented in this workshop should underpin future workshops and enable collaborations that bridge the many disciplines that are part of PCE3.","PeriodicalId":19614,"journal":{"name":"Origins of Life and Evolution of Biospheres","volume":null,"pages":null},"PeriodicalIF":2.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9261198/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40567043","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

On the Origin of Sugar Handedness: Facts, Hypotheses and Missing Links-A Review. 论糖手的起源：事实、假设和缺失的环节——综述。

IF 2 4区物理与天体物理

Origins of Life and Evolution of Biospheres Pub Date : 2022-09-01 Epub Date: 2022-07-07 DOI: 10.1007/s11084-022-09624-9

R Fernando Martínez, Louis A Cuccia, Cristóbal Viedma, Pedro Cintas

{"title":"On the Origin of Sugar Handedness: Facts, Hypotheses and Missing Links-A Review.","authors":"R Fernando Martínez, Louis A Cuccia, Cristóbal Viedma, Pedro Cintas","doi":"10.1007/s11084-022-09624-9","DOIUrl":"https://doi.org/10.1007/s11084-022-09624-9","url":null,"abstract":"By paraphrasing one of Kipling's most amazing short stories (How the Leopard Got His Spots), this article could be entitled \"How Sugars Became Homochiral\". Obviously, we have no answer to this still unsolved mystery, and this perspective simply brings recent models, experiments and hypotheses into the homochiral homogeneity of sugars on earth. We shall revisit the past and current understanding of sugar chirality in the context of prebiotic chemistry, with attention to recent developments and insights. Different scenarios and pathways will be discussed, from the widely known formose-type processes to less familiar ones, often viewed as unorthodox chemical routes. In particular, problems associated with the spontaneous generation of enantiomeric imbalances and the transfer of chirality will be tackled. As carbohydrates are essential components of all cellular systems, astrochemical and terrestrial observations suggest that saccharides originated from environmentally available feedstocks. Such substances would have been capable of sustaining autotrophic and heterotrophic mechanisms integrating nutrients, metabolism and the genome after compartmentalization. Recent findings likewise indicate that sugars' enantiomeric bias may have emerged by a transfer of chirality mechanisms, rather than by deracemization of sugar backbones, yet providing an evolutionary advantage that fueled the cellular machinery.","PeriodicalId":19614,"journal":{"name":"Origins of Life and Evolution of Biospheres","volume":null,"pages":null},"PeriodicalIF":2.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40569061","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Spontaneous Emergence of Transient Chirality in Closed, Reversible Frank-like Deterministic Models 封闭可逆类弗兰克确定性模型中瞬态手性的自发出现

IF 2 4区物理与天体物理

Origins of Life and Evolution of Biospheres Pub Date : 2022-06-10 DOI: 10.1007/s11084-022-09621-y

T. Buhse, J. Micheau

引用次数: 2

Molecular Self-Assembly as a Trigger of Life Origin and Development 分子自组装:生命起源与发展的触发器

IF 2 4区物理与天体物理

Origins of Life and Evolution of Biospheres Pub Date : 2022-04-20 DOI: 10.1007/s11084-022-09620-z

D. Zlenko, A. M. Zanin, S. Stovbun

引用次数: 2

Gaia as Solaris: An Alternative Default Evolutionary Trajectory 盖亚作为索拉里斯:另一种默认进化轨迹

IF 2 4区物理与天体物理

Origins of Life and Evolution of Biospheres Pub Date : 2022-01-05 DOI: 10.1007/s11084-022-09619-6

S. Janković, Ana Katić, M. 'Cirkovi'c

引用次数: 3

Computational Study of the Stability of Natural Amino Acid isomers. 天然氨基酸异构体稳定性的计算研究。

IF 2 4区物理与天体物理

Origins of Life and Evolution of Biospheres Pub Date : 2021-12-01 Epub Date: 2021-11-05 DOI: 10.1007/s11084-021-09615-2

Stefano Crespi, Dhanalakshmi Vadivel, Alfredo Bellisario, Daniele Dondi

引用次数: 2