Open Access Library Journal最新文献_第2页

Book Review on Comenius’s School of Infancy 夸美纽斯的婴儿学派书评

Open Access Library Journal Pub Date : 2021-06-11 DOI: 10.4236/OALIB.1107491

Zhao Nian

引用次数: 1

Searching if SARS-CoV-2 Subsists Following the Disinfection of Potable Water 搜索饮用水消毒后是否存在SARS-CoV-2

Open Access Library Journal Pub Date : 2021-06-08 DOI: 10.4236/OALIB.1107505

D. Ghernaout, N. Elboughdiri

引用次数: 2

The Relationship between the Conflicts and the Conflict Management Styles of Police Officers in the Philippines 菲律宾警察冲突与冲突管理方式之关系

Open Access Library Journal Pub Date : 2021-06-01 DOI: 10.4236/OALIB.1107540

Xyra Rose A. Galman, Sheena Mai A. Galman, Jocelyn B. Cruz, Mercedes D. Santos

引用次数: 1

Movement for the “Emancipation of the Niger Delta” (MEND) Constitutes a Threat to the U.S. National Security “尼日尔三角洲解放运动”(MEND)对美国国家安全构成威胁

Open Access Library Journal Pub Date : 2021-06-01 DOI: 10.4236/OALIB.1107465

Mustapha Kulungu

引用次数: 0

The Significance of Particle’s Density in Quantum Field Theory 粒子密度在量子场论中的意义

Open Access Library Journal Pub Date : 2021-05-26 DOI: 10.4236/OALIB.1107384

E. Comay

引用次数: 0

Probing of Interaction between Alogliptin Benzoate and Human Serum Albumin Using Multi-Spectral Methods and Molecule Docking Technique 应用多光谱法和分子对接技术探讨阿格列汀与人血清白蛋白的相互作用

Open Access Library Journal Pub Date : 2021-05-06 DOI: 10.4236/OALIB.1107283

N. Zhang, Jianbo Chen, Zhuowei Han

{"title":"Probing of Interaction between Alogliptin Benzoate and Human Serum Albumin Using Multi-Spectral Methods and Molecule Docking Technique","authors":"N. Zhang, Jianbo Chen, Zhuowei Han","doi":"10.4236/OALIB.1107283","DOIUrl":"https://doi.org/10.4236/OALIB.1107283","url":null,"abstract":"The interaction of alogliptin benzoate with human serum albumin had been characterized under physiological conditions using multi-spectral methods and molecular docking technique. The work presented in this paper focused on the interaction mechanism, the conformational changes of HSA and the binding sites of alogliptin benzoate with human serum albumin. The binding distance, binding constants, the number of binding sites and the binding forces had been investigated through fluorescence and spectral overlaps. Results indicated the presence of static quenching between alogliptin benzoate and human serum albumin. Moreover, the van der Waals forces and hydrogen bonding drove the binding process. The analysis results of UV–vis absorption spectroscopy, synchronous fluorescence spectrometry, circular dichroism spectroscopy and three-dimensional fluorescence spectroscopy revealed that alogliptin benzoate changed the conformation of human serum albumin. In addition, molecule docking and competitive experimental results suggested the binding sites located at IIA subdomain of human serum albumin. This research is vital to providing reference for studying the pharmacodynamics and pharmacokinetics mechanisms of alogliptin benzoate.","PeriodicalId":19593,"journal":{"name":"Open Access Library Journal","volume":"84 1","pages":"1-16"},"PeriodicalIF":0.0,"publicationDate":"2021-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84749204","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Study on Guidance and Incentive Measures for Undergraduate Entrepreneurship 大学生创业的引导与激励措施研究

Open Access Library Journal Pub Date : 2021-05-06 DOI: 10.4236/OALIB.1107422

Junjie Zhao, Xiao-rong Zhao

引用次数: 5

Sustainable Development Goals (SDG) Target 6.2 in Ethiopia: Challenges and Opportunities 埃塞俄比亚的可持续发展目标6.2:挑战与机遇

Open Access Library Journal Pub Date : 2021-05-06 DOI: 10.4236/OALIB.1107458

Desale Baye

{"title":"Sustainable Development Goals (SDG) Target 6.2 in Ethiopia: Challenges and Opportunities","authors":"Desale Baye","doi":"10.4236/OALIB.1107458","DOIUrl":"https://doi.org/10.4236/OALIB.1107458","url":null,"abstract":"Sanitation is deemed to be a human right. Improved sanitation service access is essential for every community’s socio-economic well-being and sustainable development. However, there has been limited research that has evaluated many current sanitation practices across various areas in Ethiopia. Therefore, the purpose of this paper was to assess the Sustainable Development Goals (SDGs) 6.2 in Ethiopia, concerning major challenges and opportunities available towards achieving SDG targets. The data used to evaluate this review was obtained from WHO/UNICEF Joint Monitoring Programme (JMP) report, Ethiopian Demographic Health Survey (EDHS) data, and scientific journal publications stemming mostly from the last decade, to show the research results on water and sanitation, particularly SDGs 6.2 prospects and challenges to provide a general outlook for policymakers in Ethiopia. As a result, this paper analyzed that even though Ethiopia had substantial progress in improving sanitation facilities in the past decades; its coverage is still one of the lowest throughout the globe. Currently, nearly 70 million people (out of about 115 million people) are using unimproved sanitation facilities in Ethiopia. The main reasons for this lowest achievement are as follows: Firstly, sanitation doesn’t have a specific organizational “home,” implying that roles are disseminated across many sectors. Secondly, the amount of money allocated to the sector is low, and liquid waste disposal facilities are almost non-existent. Thirdly, the sanitation strategy’s implementation is not straightforward. Given the existing state of knowledge, the most important strategies needed to tackle the multilateral problem in Ethiopia will be defining specifically identified institutional accountability, capacity building and awareness creation, clear sanitation resource allocation and sustainable sanitation approach concerned with the protection of the environment. The analysis of challenges and opportunities for sanitation services in Ethiopia might be useful for the improvement of SDG 6.2 in other developing countries.","PeriodicalId":19593,"journal":{"name":"Open Access Library Journal","volume":"72 1","pages":"1-28"},"PeriodicalIF":0.0,"publicationDate":"2021-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80903320","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

Dose Load during Angiographic Procedures RCA Stenting 血管造影过程中的剂量负荷

Open Access Library Journal Pub Date : 2021-05-06 DOI: 10.4236/OALIB.1107409

Javor Ivanov

{"title":"Dose Load during Angiographic Procedures RCA Stenting","authors":"Javor Ivanov","doi":"10.4236/OALIB.1107409","DOIUrl":"https://doi.org/10.4236/OALIB.1107409","url":null,"abstract":"This article is a continuation of the study of the dose load received by an interventional cardiologist during angiographic procedures and particularly during RCA stenting. To calculate the dose load, dosimetric measurements of the effective dose were carried out while working with a Philips Allura Xper FD10 angiographic system in the invasive department of the Special Hospital for Active Treatment in Cardiology, Varna, Bulgaria. The measurements were carried out for the two operating modes of the angiographic system—radio- graphy and pulse fluoroscopy. In order to obtain a clear assessment of the received dose of the principal cardiologist, the measurements were carried out for three positions of the patient table—zero, lowest and highest position, as well as for three control points: “Head”, “Gonads”, “Feet”. In this procedure following projections are used: LAO-cranial—as first basic projection, RAO- cranial—as second basic and Pure Сranial—as third basic projection. For this reason, calculations have been made for each of these projections. The results convincingly show maximum dose load when radiography is used, although the duration of radiography is significantly shorter than the duration of pulse fluoroscopy. A concluded that the position of the patient table is important during the work of the principal cardiologist and the use of individual radiation protection equipment is not only recommended, but should be mandatory, as indicated in both Bulgarian and international legislation.","PeriodicalId":19593,"journal":{"name":"Open Access Library Journal","volume":"93 1","pages":"1-12"},"PeriodicalIF":0.0,"publicationDate":"2021-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90738380","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Scan Features of Brain Damage during Trauma in Kinshasa, Democratic Republic of Congo: A Case Series Study 刚果民主共和国金沙萨创伤期间脑损伤的扫描特征:一个案例系列研究

Open Access Library Journal Pub Date : 2021-05-06 DOI: 10.4236/OALIB.1107426

Samuel Bula Mbaki, A. Nkodila, M. Lelo, B. Longo

{"title":"Scan Features of Brain Damage during Trauma in Kinshasa, Democratic Republic of Congo: A Case Series Study","authors":"Samuel Bula Mbaki, A. Nkodila, M. Lelo, B. Longo","doi":"10.4236/OALIB.1107426","DOIUrl":"https://doi.org/10.4236/OALIB.1107426","url":null,"abstract":"Background and aim: Brain trauma and various neurological disorders represent a significant cause of morbidity and mortality throughout the world. But data relating to this in sub-Saharan Africa is scarce. The aim of the study is to identify traumatic pathologies by CT scan in patients followed in hospitals in Kinshasa, Democratic Republic of Congo. Methods: descriptive cross-sectional study of data from the medical records of patients having performed a brain CT scan covering a period of 24 months at the University Clinics of Kinshasa and at the Biamba Marie Mutombo Hospital. There are three types of study parameters, those relating to socio-demographic data (age, sex, date of the CT scan); those relating to the clinical data and the indications for the examination and the CT data. Results: 746 presented trauma assessment against 2433 patients for a non-traumatic indication. The mean age was 47.1 ± 20.9 years. There was a statistically significant and unequal distribution of the proportions of indications for brain scan according to age groups: the age group < 40 years coinciding exclusively in the traumatic assessment against non-traumatic indications for patients ≥ 60 years of age. Of the many traumatic injuries seen on a brain scan, bone fractures, intracranial hematomas and brain contusions were the most common injuries. Conclusion: traumatic lesions on CT are frequent in Kinshasa; they are characterized by the presence of bone fractures, intracranial hematomas and cerebral contusions.","PeriodicalId":19593,"journal":{"name":"Open Access Library Journal","volume":"103 1","pages":"1-8"},"PeriodicalIF":0.0,"publicationDate":"2021-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87983235","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0