Open Access Journal of Microbiology & Biotechnology最新文献_第2页

A Review of Emerging Health Risks with 3-MCPD Processing Contaminant in Refined Edible Oils 精制食用油中3-MCPD加工污染物的健康风险研究进展

Open Access Journal of Microbiology & Biotechnology Pub Date : 2021-01-01 DOI: 10.23880/oajmb-16000202

Rania IM Almoselh, Rania I.M. Almoselhy

{"title":"A Review of Emerging Health Risks with 3-MCPD Processing Contaminant in Refined Edible Oils","authors":"Rania IM Almoselh, Rania I.M. Almoselhy","doi":"10.23880/oajmb-16000202","DOIUrl":"https://doi.org/10.23880/oajmb-16000202","url":null,"abstract":"Processing contaminants are chemical substances that have not been intentionally added to edible oils or food. These substances may be present in edible oils and food as a result of the various stages of its production, processing, transport or environmental contamination and may pose a risk to animal and human health. Processing methods include fermentation, smoking, drying, refining and high-temperature cooking. Many foods must be cooked to actually be edible and digestible. It also makes them tastier. However, baking, frying, grilling or barbecuing, either at home or in manufacturing, can have undesired consequences. Besides the loss of some nutrients like vitamins, potentially harmful by-products can develop too. 3-Monochloropropanediol (3-MCPD) is an organic chemical compound, one of the heat- and process-induced food contaminants, belonging to a group called chloropropanols and is considered as the most toxic processing contaminant emerging during thermal treatments in refining of edible oils. The aim of this review was to provide an overview of current knowledge regarding 3-MCPD in edible oils for further research, in order to reduce its contents in consumed foodstuffs.","PeriodicalId":19559,"journal":{"name":"Open Access Journal of Microbiology & Biotechnology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75827225","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Nanoparticles: Characterization, Biological Synthesis and Applications 纳米粒子:表征、生物合成及其应用

Open Access Journal of Microbiology & Biotechnology Pub Date : 2021-01-01 DOI: 10.23880/oajmb-16000196

Elkhateeb Wa

引用次数: 0

Potentially Beneficial Comamonas Testosteroni Bacteria for Plants Growing in HCB-Polluted Soil 在hcb污染的土壤中生长的植物的潜在有益的睾酮单胞菌

Open Access Journal of Microbiology & Biotechnology Pub Date : 2021-01-01 DOI: 10.23880/oajmb-16000208

D. M.

引用次数: 0

Short Note on Biotechnological Application of Halophilic Enzymes 嗜盐酶生物技术应用综述

Open Access Journal of Microbiology & Biotechnology Pub Date : 2021-01-01 DOI: 10.23880/oajmb-16000200

J. H.

引用次数: 1

Refractory Multi-inflammatory Syndrome in a two weeks old neonate with COVID-19 Treated Successfully with Intravenous Immunoglobulin, Steroids and Anakinra 静脉注射免疫球蛋白、类固醇和阿那白成功治疗两周大新生儿COVID-19难治性多重炎症综合征

Open Access Journal of Microbiology & Biotechnology Pub Date : 2020-08-24 DOI: 10.21203/rs.3.rs-60510/v1

S. Magboul, Ahmed Khalil, Ahmad Alshami, Mohamed Alaido, Abdulla Alhothi, Khaled Ellithy, Mohamed Al Amri, Manasik Hassan

{"title":"Refractory Multi-inflammatory Syndrome in a two weeks old neonate with COVID-19 Treated Successfully with Intravenous Immunoglobulin, Steroids and Anakinra","authors":"S. Magboul, Ahmed Khalil, Ahmad Alshami, Mohamed Alaido, Abdulla Alhothi, Khaled Ellithy, Mohamed Al Amri, Manasik Hassan","doi":"10.21203/rs.3.rs-60510/v1","DOIUrl":"https://doi.org/10.21203/rs.3.rs-60510/v1","url":null,"abstract":"\u0000 Background: World Health Organization (WHO) and other Health officials alert clinicians about a rare but severe inflammatory condition seen in children and linked to Corona Virus Disease 2019(COVID-19). The WHO is describing the condition as a multisystem inflammatory syndrome in children (MIS-C) and is recommending clinicians to report those cases to get a better understanding of the disease and clinicians can learn more.Case presentation: We are reporting the clinical course of the youngest case of COVID-19 related MIS-c; a two-week-old term neonate with COVID-19 infection and features suggestive of MIS-C , managed with intravenous immunoglobulin (IVIG), pulse steroid, and interleukin-1 inhibitor (Anakinra).By reviewing the literature, our baby is the first neonatal case who has been diagnosed with MIS-C.Conclusion: COVID-19 infection in pediatrics are likely to present with a mild course; however, some may develop a hyper-inflammatory syndrome. Pediatricians should be aware of such presentation, the clinical course, the management modalities, and inform parents and caregivers about common signs and symptoms. Anakinra may consider as effective second agent in (IVIG and steroid-refractory pediatric cases).","PeriodicalId":19559,"journal":{"name":"Open Access Journal of Microbiology & Biotechnology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88855639","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

HER2 Receptor Overexpression in Gastric Adenocarcinoma A Study about a Sampling of 50 Cases in Dakar HER2受体在胃腺癌中的过表达——来自达喀尔50例样本的研究

Open Access Journal of Microbiology & Biotechnology Pub Date : 2019-01-01 DOI: 10.23880/oajmb-16000151

Bentefouet Tl

{"title":"HER2 Receptor Overexpression in Gastric Adenocarcinoma A Study about a Sampling of 50 Cases in Dakar","authors":"Bentefouet Tl","doi":"10.23880/oajmb-16000151","DOIUrl":"https://doi.org/10.23880/oajmb-16000151","url":null,"abstract":"ntroduction: HER2 receptor overexpression in gastric or gastroesophageal junction (GOJ) adenocarcinoma is a factor of poor prognosis detected in 7 to 34% of gastric and GOJ adenocarcinomas. The objective of this study was to evaluate the overexpression of the HER2 receptor in gastric adenocarcinomas in Dakar, and to investigate the correlation between HER2 overexpression and clinicopathological parameters. Patients and method: This is a retrospective, descriptive and analytical study that was conducted over a one - year period; from 1 January 2016 to 31 December 2017. It involves 50 cases of gastric or GOJ adenocarcinomas histologically confirmed on biopsy samplings, collected within pathological anatomy and cytology services in Dakar (HALD a nd HOGGY). The study of HER2 receptor overexpression was performed on tumor samples put in buffered formalin and embedded in paraffin using the immunohistochemical method. Results: The average age was 58.18 ± 14.6 years. A male predominance was observed, w ith a gender ratio of 1.27. Tumors were ulcero budding in 76% of cases. They were found at the gastric level in 92% of the surveyed cases, and at the gastroesophageal junction in 8% of them. Adenocarcinomas were of tubulous type in 76% of cases, and they w ere markedly differentiated in 54% of cases. At immunohistochemical study, the positivity rate of the HER2 was 8% out of the 50 cases that were tested. There was no correlation between HER2 overexpression and those clinicopathological parameters . Con clusion: HER2 is a factor of poor prognosis but it is also a therapeutic response factor to anti - HER2s. Assessment of the HER2 status should be systematic in all cases of gastric adenocarcinoma; and it requires a multidisciplinary approach.","PeriodicalId":19559,"journal":{"name":"Open Access Journal of Microbiology & Biotechnology","volume":"17 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84258558","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Novel Member of the Subtilisin - Like Protease Family from Bacillus pumilus 7Р: Properties and Applications 矮芽孢杆菌类枯草杆菌蛋白酶家族的新成员7Р:性质和应用

Open Access Journal of Microbiology & Biotechnology Pub Date : 2019-01-01 DOI: 10.23880/oajmb-16000152

S. M.

引用次数: 0

Synthesis, Antibacterial and Antifungal Properties of Cyclohexane Tosyloxyimine Derivative 环己烷Tosyloxyimine衍生物的合成及其抑菌抑菌性能

Open Access Journal of Microbiology & Biotechnology Pub Date : 2019-01-01 DOI: 10.23880/oajmb-16000150

M. Shoaib

引用次数: 2

An Assessment of Alternative Therapeutic Options for the Treatment of Prolonged Zoonotic Fungal Infections in Companion Animals 伴侣动物长期人畜共患真菌感染的替代治疗方案评估

Open Access Journal of Microbiology & Biotechnology Pub Date : 2019-01-01 DOI: 10.23880/oajmb-16000149

Garvey M

{"title":"An Assessment of Alternative Therapeutic Options for the Treatment of Prolonged Zoonotic Fungal Infections in Companion Animals","authors":"Garvey M","doi":"10.23880/oajmb-16000149","DOIUrl":"https://doi.org/10.23880/oajmb-16000149","url":null,"abstract":"Zoonotic disease is an ongoing issue, becoming more prominent as more microbial species display antimicrobial resistance. The role of companion animals in society is also increasing as therapy dogs become the mainstay for many special needs persons. In order to ensure public health safety, it is essent ial to determine the extent of resistance amongst zoonotic pathogens and where possible to suggest novel treatment options to counteract such resistance. Fungal species are increasingly recognised as the causative agent in numerous incidents of canine morb idity. Therefore, the development of new, safe and effective chemotherapeutic agents is essential to prevent and control mycotic disease. Chronic incidents of cutaneous candidiasis as diagnosed in the cases used for this study are particularly high risk fo r zoonotic transmission. Studies described herein evaluate the resistance of these canine isolates of Candida species to common antifungal agents and identify levels of resistance using recognised in vitro methods. Results show high levels of resistance to amphotericin B, fluconazole and caspofungin for Candida albicans and Candida krusei isolates. This clinical resistance was more prominent in isolated species compared to control species. Novel compounds namely phendione and Roussin Black salts show promis ing antifungal activity with minimum inhibitory concentrations determined.","PeriodicalId":19559,"journal":{"name":"Open Access Journal of Microbiology & Biotechnology","volume":"124 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78118802","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Fusarium Wilt Disease of Banana: Current Development of Fusarium Resistant Banana 香蕉枯萎病:香蕉抗枯萎病研究进展

Open Access Journal of Microbiology & Biotechnology Pub Date : 2019-01-01 DOI: 10.23880/OAJMB-16000134

C. Teo

引用次数: 1