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Organic Chemistry: An Indian Journal最新文献

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Synthesis and Anti Convulsant Activity of Novel Oxadiazole Substituted Phenothiazine Derivatives 新型恶二唑取代吩噻嗪衍生物的合成及其抗惊厥活性
Organic Chemistry: An Indian Journal Pub Date : 2021-05-05 DOI: 10.9734/BPI/CACB/V4/1783F
Dighe Ns, Bankar Aa, DS Musmade, S. Nirmal
{"title":"Synthesis and Anti Convulsant Activity of Novel Oxadiazole Substituted Phenothiazine Derivatives","authors":"Dighe Ns, Bankar Aa, DS Musmade, S. Nirmal","doi":"10.9734/BPI/CACB/V4/1783F","DOIUrl":"https://doi.org/10.9734/BPI/CACB/V4/1783F","url":null,"abstract":"The research is directed towards the synthesis and evaluation of novel agents for the treatment of various neurological disorders. The phenothiazine nucleus has been well explored for the various biological activities in past. The oxadiazole substituted phenothiazine have been of keen interest as a drug candidate for the treatment of various neurological disorders. In view of these an attempt has been made to synthesize substituted phenothiazine and explore them for promising anti convulsant activity. The anti-convulsant activity of synthesized compounds had been done by using Strychnine induced and 4-amino pyridine induced models.","PeriodicalId":19541,"journal":{"name":"Organic Chemistry: An Indian Journal","volume":"140 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80285964","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Polymeric Composite Materials Based on Silicate: I-Synthesis, Characterization and Formation Mechanism 硅酸盐高分子复合材料的合成、表征及形成机理
Organic Chemistry: An Indian Journal Pub Date : 2018-01-23 DOI: 10.26671/IJIRG.2017.3.6.102
A. Mm, M. Abass, A. B. Ibrahim, E. S. Zakaria, A. Hassan
{"title":"Polymeric Composite Materials Based on Silicate: I-Synthesis, Characterization and Formation Mechanism","authors":"A. Mm, M. Abass, A. B. Ibrahim, E. S. Zakaria, A. Hassan","doi":"10.26671/IJIRG.2017.3.6.102","DOIUrl":"https://doi.org/10.26671/IJIRG.2017.3.6.102","url":null,"abstract":"Magneso-silicate has been synthesized by precipitation technique. Polyacrylamide acrylic acid and polyacrylamide acrylonitrile impregnated with inorganic ion exchanger, magneso-silicate, have been synthesized by subjected co-monomers to gamma radiation initiated polymerization at radiation doses 25, 65 and 90 KGy. The structure features of composites were investigated by sequential x-ray fluorescence spectrometer, x-ray diffraction, differential thermal- thermogravimetric analyses and infrared spectroscopy. Formation mechanism for these composites was conducted and the results obtained showed that the polymerization process was carried out in the hydrocarbon chain by addition polymerization whereas impregnation of magneso-silicate into the polymeric composites was carried out by condensation polymerization.","PeriodicalId":19541,"journal":{"name":"Organic Chemistry: An Indian Journal","volume":"99 1","pages":"121"},"PeriodicalIF":0.0,"publicationDate":"2018-01-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77573299","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Synthesis of C-glycosides from 1,6-Diamino-4-Phenylpyridine Derivatives 1,6-二氨基-4-苯基吡啶衍生物合成c -糖苷
Organic Chemistry: An Indian Journal Pub Date : 2014-01-01 DOI: 10.13189/UJC.2014.020503
A. Amer, A. Ghoneim, Mohamed H.Sherif, W. Farouk
{"title":"Synthesis of C-glycosides from 1,6-Diamino-4-Phenylpyridine Derivatives","authors":"A. Amer, A. Ghoneim, Mohamed H.Sherif, W. Farouk","doi":"10.13189/UJC.2014.020503","DOIUrl":"https://doi.org/10.13189/UJC.2014.020503","url":null,"abstract":"Diamino 3a and 3b derivatives which obtained by Michael reaction were coupled with aldoses in the presence of acetic acid and I2 with stirring at roomtemperature gave 4, 5 and 6 respectively.Acetylation of compound 4 and 5 gave compound 7 and 8 respectively. Coupling of fructose with 3a and 3b in the presence or not of Con HCl gave compound 9 and 11 respectively. Acetylation of compound 9 with acetic anhydride and Pyridine gave compound 10. Some of the synthesized compounds have been screened as antibacterial and antifungal. The structures of the synthesized compounds have been deduced from their elemental analysis and spectral (IR, 1HNMR) data.","PeriodicalId":19541,"journal":{"name":"Organic Chemistry: An Indian Journal","volume":"103 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2014-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86429261","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Starch sulfuric acid: An alternative, eco-friendly catalyst for Biginelli reaction 淀粉硫酸:一种替代的、环保的比基内利反应催化剂
Organic Chemistry: An Indian Journal Pub Date : 2013-12-01 DOI: 10.19261/CJM.2013.08(2).13
R. Rezaei, M. Farjam, Sara Malek, M. Sheikhi
{"title":"Starch sulfuric acid: An alternative, eco-friendly catalyst for Biginelli reaction","authors":"R. Rezaei, M. Farjam, Sara Malek, M. Sheikhi","doi":"10.19261/CJM.2013.08(2).13","DOIUrl":"https://doi.org/10.19261/CJM.2013.08(2).13","url":null,"abstract":"The one-pot multicomponent synthesis of 3,4-dihydropyrimidinone derivativesusingstarch sulfuric acid as an environmentallyfriendly biopolymerbased solid acid catalyst from aldehydes, â-keto esters and urea/thiourea without solvent is described. Compared with classical Biginelli reaction conditions, this new methodhas the advantage of minimizing the cost operational hazards and environmental pollution, good yields, shorter reaction times and simplework-up.","PeriodicalId":19541,"journal":{"name":"Organic Chemistry: An Indian Journal","volume":"113 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2013-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81715813","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Topological descriptors based quantitative structure activity relationship study of aromatic amines 基于拓扑描述符的芳香胺定量构效关系研究
Organic Chemistry: An Indian Journal Pub Date : 2008-01-01 DOI: 10.24214/jcbps.a.8.3.39299
P.P.Singh, A. Prajapati
{"title":"Topological descriptors based quantitative structure activity relationship study of aromatic amines","authors":"P.P.Singh, A. Prajapati","doi":"10.24214/jcbps.a.8.3.39299","DOIUrl":"https://doi.org/10.24214/jcbps.a.8.3.39299","url":null,"abstract":"QSAR study of 29 aniline derivatives whose carcinogenic activities are reported in terms of log P has been made. QSAR models have been developed with the help of descriptors,connectivity index,valence connectivity index,shape index,molecularweight,accessibility surface area andmolar refractivity. Thirty-eight models have been found to have high degree of predictive power with regression coefficient above 0.9 and 12models above 0.9597. The combination of descriptors providing the best model is log P,valence connectivity index,shape index and molecular weight.","PeriodicalId":19541,"journal":{"name":"Organic Chemistry: An Indian Journal","volume":"35 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2008-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78023617","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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